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Directly wireless communication of human minds via non-invasive brain-computer-metasurface platform

eLight 2022年第1期2卷 132-142页

作者： Qian Ma wei Gao Qiang Xiao Lingsong Ding Tianyi Gao Yajun Zhou Xinxin Gao Tao Yan Che Liu Ze Gu Xianghong Kong Qammer hAbbasi Lianlin Li Cheng‑wei Qiu Yuanqing Li Tie Jun Cui Institute of Electromagnetic Space Southeast UniversityNanjing 210096China School of Automation Science and Engineering South China University of TechnologyGuangzhou 510641China State Key Laboratory of Millimeter wave Southeast UniversityNanjing 210096China Center of Intelligent Metamaterials Pazhou Laboratory Guangzhou 510330China Research Center for Brain-Computer Interface Pazhou LabGuangzhou 510330China Department of Electrical and Computer Engineering National University of SingaporeSingaporeSingapore University of Glasgow James Watt School of EngineeringGlasgow G128QQUK State Key Laboratory of Advanced Optical Communication Systems and Networks Department of ElectronicsPeking UniversityBeijing 100871China

Brain-computer interfaces(BCIs),invasive or non-invasive,have projected unparalleled vision and promise for assisting patients in need to better their interaction with the *** by the BCI-based rehabilitation technologies for nerve-system impairments and amputation,we propose an electromagnetic brain-computer-metasurface(EBCM)paradigm,regulated by human’s cognition by brain signals directly and *** experimentally show that our EBCM platform can translate human’s mind from evoked potentials of P300-based electroencephalography to digital coding information in the electromagnetic domain non-invasively,which can be further processed and transported by an information metasurface in automated and wireless *** wireless communications of the human minds are performed between two EBCM operators with accurate text ***,several other proof-of-concept mind-control schemes are presented using the same EBCM platform,exhibiting flexibly-customized capabilities of information processing and synthesis like visual-beam scanning,wave modulations,and pattern encoding.

关键词： communication computer surface

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1,3-二氧环辛烷-2-羧酸类三环化合物的合成及其除草活性

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浙江化工 2000年第C期31卷 26-26页

作者：李斌满瀛张宗俭 Colin M Tice Lori A.Spangler james Gallagher Lois M. Bryman howard C. Smith Manuel V. Nunez 沈阳化工研究院沈阳110021 Rohm and haas Company Spring house Rohm

12h－Dibenzo d,g 1,3 dioxocin－6－carboxylic acid is a patented herbicide (US4976770)with good pre－and post－emergence activity on dicot weeds and sedges． Structure activity studies were initiated with the goal of discovering more synthetically accessible analogs with improved unit activity and crop－weed *** improved procedure to prepare the lead compound was *** were prepared in which both the tricyclic core and the carboxylic acid function were *** synthesis and screening results of these analogs will be presented．

关键词：二氧环辛烷羧酸类三环化合物除草活性除草剂

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家族性渗出性玻璃体视网膜病遗传异质性的进一步证据:在一个常染色体显性遗传大家系中排除EVR1,EVR3,EVR4

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世界核心医学期刊文摘（眼科学分册） 2005年第6期1卷 29-29页

作者： Toomes C. Downey L.M. Bottomley h.M. 王海燕 MolecularMedicineUnit Clinical Sciences Building St. James' s University Hospital Leeds LS9 7TF United Kingdom

Background/aims: Familial exudative vitreoretinopathy (FEVR) is an inherited blinding condition characterised by abnormal development of the retinal vasculature. The aim of this study was to perform linkage analysis in a large family affected with FEVR to determine whether the mutation involved was in one of the three known autosomal dominant FEVR loci or in another as yet unidentified gene. Methods: Genomic DNA samples from family members were polymerase chain reaction (PCR) amplified with fluorescently tagged microsatellite markers spanning the EVR1/EVR4 locus (11q13- 14) and the EVR3 locus (11p12- 13). The resulting PCR products were resolved using an automated DNA sequencer and the alleles sized. These data were used to construct haplotypes across each locus and linkage analysis was performed to prove or exclude linkage. Results: The clinical evaluation in this family suggested features typical of FEVR, with deficient peripheral retinal vascularisation being the common phenotype in all affected individuals. however, linkage analysis proved that this family has a form of FEVR genetically distinct from the EVR1, EVR3 and EVR4 loci. Conclusion: The exclusion of linkage in this family to any of the known FEVR loci proves the existence of a fourth locus for autosomal dominant FEVR and shows that this rare disorder is far more heterogeneous than previously thought.

关键词：玻璃体视网膜 EVR1,EVR3,EVR4 渗出性族性视网膜血管遗传异质性连锁分析聚合酶链反应基因位点测序仪

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肝脏纤毛性前肠囊肿

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世界核心医学期刊文摘（儿科学分册） 2006年第11期2卷 50-50页

作者： Stringer M.D. Jones M.O. woodley h. wyatt J. 刘凯 Children's Liver Unit St. James's University Hospital LS9 7TF Leeds United Kingdom

A male infant was found to have a large congenital hepatic cyst,first noted in late gestation by prenatal ultrasound scan. The cyst communicated with the biliary tree and was eventually removed completely by an extended right hepatectomy. histopathologic examination showed a thick-walled, unilocular cyst lined predominantly by ciliated, stratified squamous epithelium with an outer wall composed of smooth muscle cells and fibrous *** features are diagnostic of a ciliated hepatic foregut cyst,a rare congenital malformation with histologic similarities to bronchogenic cysts. The young age of our patient, prenatal detection, large size of the cyst, and a clear communication with the biliary tree have not been previously described with ciliated hepatic foregut cysts.

关键词：肠囊肿胆管系统肝右叶扩大切除术产前超声检查单房性支气管囊肿先天性畸形交通支复层扁平

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Decline in subarachnoid haemorrhage volumes associated with the first wave of the COVID- 19 pandemic

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Stroke & Vascular Neurology 2021年第4期6卷 542-552,I0026-I0032页

作者： Thanh N Nguyen Diogo C haussen Muhammad M Qureshi hiroshi Yamagami Toshiyuki Fujinaka Ossama Y Mansour Mohamad Abdalkader Michael Frankel Zhongming Qiu Allan Taylor Pedro Lylyk Omer F Eker Laura Mechtouff Michel Piotin Fabricio Oliveira Lima Francisco Mont'Alverne wazim Izzath Nobuyuki Sakai Mahmoud Mohammaden Alhamza R Al-Bayati Leonardo Renieri Salvatore Mangiafico David Ozretic Vanessa Chalumeau Saima Ahmad Umair Rashid Syed Irteza hussain Seby John Emma Griffin John Thornton Jose Antonio Fiorot Rodrigo Rivera Nadia hammami Anna M Cervantes-Arslanian hormuzdiyar h Dasenbrock huynh Le Vu Viet Quy Nguyen Steven hetts Romain Bourcier Romain Guile Melanie walker Malveeka Sharma Don Frei Pascal Jabbour Nabeel herial Fawaz Al-Mufti Atilla Ozcan Ozdemir Ozlem Aykac Dheeraj Gandhi Chandril Chugh Charles Matouk Pascale Lavoie Randall Edgell Andre Beer-Furlan Michael Chen Monika Killer-Oberpfalzer Vitor Mendes Pereira Patrick Nicholson Vikram huded Nobuyuki Ohara Daisuke watanabe Dong hun Shin Pedro SC Magalhaes Raghid Kikano Santiago Ortega-Gutierrez Mudassir Farooqui Amal Abou-hamden Tatsuo Amano Ryoo Yamamoto Adrienne weeks Elena A Cora Rotem Sivan-hoffmann Roberto Crosa Markus Möhlenbruch Simon Nagel hosam Al-Jehani Sunil A Sheth Victor S Lopez Rivera james E Siegler Achmad Fidaus Sani Ajit S Puri Anna Luisa Kuhn Gianmarco Bernava Paolo Machi Daniel G Abud Octavio M Pontes-Neto Ajay K wakhloo Barbara Voetsch Eytan Raz Shadi Yaghi Brijesh P Mehta Naoto Kimura Mamoru Murakami Jin Soo Lee Ji Man hong Robert Fahed Gregory walker Eiji hagashi Steve M Cordina hong Gee Roh Ken wong Juan F Arenillas Mario Martinez-Galdamez Jordi Blasco Alejandro Rodriguez Vasquez Luisa Fonseca M Luis Silva Teddy Y wu Simon John Alex Brehm Marios Psychogios william J Mack Matthew Tenser Tatemi Todaka Miki Fujimura Roberta Novakovic Jun Deguchi Yuri Sugiura hiroshi Tokimura Rakesh Khatri Michael Kelly Lissa Peeling Yuichi Murayama hugh Stephen winters Johnny wong Mohamed Teleb Jeremy Payne hiroki Fukuda Kosuke Miyake Junsuke Shimbo Yusuke Sug Neurology RadiologyBoston Medical CenterBostonMassachusettsUSA Neurology Marcus Stroke&Neuroscience CenterGrady Memorial HospitalEmory University School of MedicineAtlantaGAUSA Radiology Radiation OncologyBoston University School of MedicineBostonMassachusettsUSA Neurology National Hospital Organization Osaka National HospitalOsakaJapan Neurosurgery National Hospital Organization Osaka National HospitalOsakaJapan Neurology Alexandria UniversityAlexandriaEgypt Radiology Boston Medical CenterBostonMassachusettsUSA Department of Neurology Xinqiao HospitalChongqingChina Neurosurgery University of Cape TownRondeboschWestern CapeSouth Africa Neurosurgery Interventional NeuroradiologyClinica La Sagrada FamiliaBuenos AiresArgentina Neuroradiologie Neurologie VasculaireHospices Civils de LyonLyonAuvergne-Rhône AlpesFrance Neurologie Vasculaire Hospices Civils de LyonLyonAuvergne-Rhône AlpesFrance Interventional Neuroradiology Fondation Ophtalmologique Adolphe de RothschildParisÎle-de FranceFrance Neurology Hospital Geral de FortalezaFortalezaBrazil Interventional Neuroradiology Hospital Geral de FortalezaFortalezaBrazil Neuroradiology Nottingham University Hospitals NHS TrustNottinghamUK Department of Neurosurgery Kobe City Medical Center General HospitalKobeHyogoJapan Interventional Neurovascular Unit University Hospital CareggiFirenzeToscanaItaly Neuroradiology University Hospital Centre ZagrebZagrebCroatia Interventional Neuroradiology Hopital BicetreLe Kremlin-BicetreFrance Stroke and Interventional Neuroradiology Lahore General HospitalLahorePakistan Neurological Institute Cleveland Clinic Abu DhabiAbu DhabiUAE Department of Radiology Beaumont HospitalDublinIreland Neurology Stroke UnitHospital-Estadual CentralVitoriaBrazil Neuroradiology Instituto de Neurocirugia Dr AsengoSantiagoChile Interventional Neuroradiology Institut National de NeurologieTunisTunisia Neurology Boston Medical CenterBostonMassachusettsUSA Neurosurgery Boston Medical Center

Background During the COVID-19 pandemic,decreased volumes of stroke admissions and mechanical thrombectomy were *** study’s objective was to examine whether subarachnoid haemorrhage(SAh)hospitalisations and ruptured aneurysm coiling interventions demonstrated similar *** we conducted a cross-sectional,retrospective,observational study across 6 continents,37 countries and 140 comprehensive stroke *** with the diagnosis of SAh,aneurysmal SAh,ruptured aneurysm coiling interventions and COVID-19 were identified by prospective aneurysm databases or by International Classification of Diseases,10th Revision,*** 3-month cumulative volume,monthly volumes for SAh hospitalisations and ruptured aneurysm coiling procedures were compared for the period before(1 year and immediately before)and during the pandemic,defined as 1 March-31 May *** prior 1-year control period(1 March-31 May 2019)was obtained to account for seasonal *** There was a significant decline in SAh hospitalisations,with 2044 admissions in the 3 months immediately before and 1585 admissions during the pandemic,representing a relative decline of 22.5%(95%CI−24.3%to−20.7%,pwith 1170-1035 procedures,respectively,representing an 11.5%(95%CI−13.5%to−9.8%,p=0.002)relative *** analysis was noted for aneurysmal SAh hospitalisation decline from 834 to 626 hospitalisations,a 24.9%relative decline(95%CI−28.0%to−22.1%,pwas noted in low coiling volume hospitals of 41.1%(95%CI 32.3%to 50.6%,p=0.008)despite a decrease in SAh admissions in this *** There was a relative decrease in the volume of SAh hospitalisations,aneurysmal SAh hospitalisations and ruptured aneurysm embolisations during the COVID-19 *** findings in SAh are consistent with a decrease in other emergencies,such as stroke and myocardial infarction.

关键词： diagnosis representing subarachnoid

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卒中一级预防指南美国心脏协会／美国卒中协会对医疗专业人员的声明

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国际脑血管病杂志 2015年第7期23卷 403-439页

作者： james F. Meschia Cheryl Bushnell Bernadette Boden-Albala Lynne T. Braun Dawn M. Bravata Seemant Chaturvedi Mark A. Creager Robert h. Eckel Mitchell S.V. Elkind Myriam Fornage Larry B Goldstein Steven M. Greenberg Susanna E. horvath Costantino Iadecola Edward C. Jauch wesley S. Moore John A. wilson 李迪高一鹭陈政弘霍晓川孙海欣孙冬玲茹小娟江滨代表美国心脏协会卒中委员会、心血管和卒中护理委员会、临床心脏病学委员会、功能基因组学和生物转化委员会以及高血压委员会北京市神经外科研究所首都医科大学首都医科大学附属北京天坛医院临床流行病学北京市重点实验室 100050

这份更新版指南旨在为既往无卒中或短暂性脑缺血发作史的人群提供适时的综合性卒中预防循证建议，包括危险因素控制、头颈部动脉粥样硬化性疾病的干预方法以及预防血栓形成和血栓栓塞性卒中的抗栓治疗。此外，本指南还提供了针对遗传和... 详细信息

这份更新版指南旨在为既往无卒中或短暂性脑缺血发作史的人群提供适时的综合性卒中预防循证建议，包括危险因素控制、头颈部动脉粥样硬化性疾病的干预方法以及预防血栓形成和血栓栓塞性卒中的抗栓治疗。此外，本指南还提供了针对遗传和药理学检测以及在其他特殊情况下（包括镰状细胞疾病和卵圆孔未闭）进行卒中预防的建议。

关键词： AhA/ASA科学声明 AF 糖尿病高脂血症高血压颅内动脉瘤缺血预防与控制吸烟卒中

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靶向微泡成像显示肿瘤新生血管:微型PET动态扫描评估小鼠体内的生物学分布

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国际医学放射学杂志 2008年第A6期31卷 502-502页

作者： J.K.willmann C.Davis A.M.Lutz M.L.Schipper C.h.Nielsen 向贤宏 Molecular Imaging Program at Stanford Department of Radiology and Bio-X Program Stanford University School of Medicine James H. Clark Center 318 Campus Dr East Wing 1st Floor Stanford CA 94305-5427 USA.

目的通过微型PET对活体小鼠的动态扫描来评价肿瘤血管内皮生成因子受体2(VEGFR2)相关的微泡靶向肿瘤新生血管在小鼠体内的分布。材料与方法

关键词：动态扫描 PET 靶向微泡 VEGFR 生成因子成像显示标记抗体摄取比放射性标记

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从小动物到大动物的人间质干细胞基因表达成像

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国际医学放射学杂志 2009年第5期32卷 486-486页

作者： J.K.willmann R.Paulmurugan M.Rodriguez-Porcel w.Stein T.J.Brinton A.J.Connolly 郭雪梅 Molecular Imaging Program at Stanford Department of Radiology and Bio-X ProgramStanford University School of MedicineJames H.Clark Center

目的采用临床PET／CT扫描，评价植入猪心肌内的人间质干细胞（MSCs）报告基因成像的可行性。材料与方法动物实验方案经实验动物保护学术委员会批准。采用不同剂量的含有巨细胞病毒（CMV）启动子的腺病毒进行人MSCs的转导，CMV启动子诱... 详细信息

目的采用临床PET／CT扫描，评价植入猪心肌内的人间质干细胞（MSCs）报告基因成像的可行性。材料与方法动物实验方案经实验动物保护学术委员会批准。采用不同剂量的含有巨细胞病毒（CMV）启动子的腺病毒进行人MSCs的转导，CMV启动子诱导变异的1型单纯疱疹病毒胸腺嘧啶脱氧核苷激酶的报告基因（Ad—CMV—hSV1-sr39tk）在细胞培养中确定其特征。

关键词：人间质干细胞基因表达成像大动物小动物 1型单纯疱疹病毒实验方案学术委员会巨细胞病毒

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变异组分析揭示番茄的育种历史

变异组分析揭示番茄的育种历史

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中国园艺学会2014年学术年会

作者：林涛祝光涛张俊红徐向阳余庆辉郑峥张忠华伦尧尧李帅王孝宣黄泽军李君明张春芝王涛涛张余洋王傲雪张艳聪林魁李传友熊国胜薛勇彪 Andrea Mazzucato Mathilde Causse Zhangjun Fei james J.Giovannoni Roger T.Chetelat Dani Zamir Thomas Stdler 李景富叶志彪杜永臣黄三文中国农业科学院蔬菜花卉研究所中国农业科学院农业基因组研究所华中农业大学东北农业大学新疆农业科学院园艺研究所北京师范大学中国科学院遗传发育研究所中国科学院北京基因组所 Department of Agriculture ForestsNatureand Energy(DAFNE)University of TusciaVia San Camillo de Lellis sncViterbo01100Italy Institut National de la Recherche Agronomique(INRA) Unite de Genetique et Amelioration des Fruits et LegumesDomaine Saint-MauriceMontfavet CedexF-84143France Boyce Thompson Institute for Plant Research U.S.Department of Agriculture(USDA) Robert W.Holley Centre for Agriculture and HealthIthacaCornell UniversityNew York14853USA C.M.Rick Tomato Genetics Resource Center Department of Plant SciencesUniversity of CaliforniaDavisCalifornia95616USA Robert h.Smith of Plant Sciences and Genetics Faculty of AgricultureThe Hebrew University of JerusalemRehovot76100Israel Plant Ecological Genetics Institute of Integrative BiologyETH ZurichZurich CH-8092Switzerland

植物基因组的变化能够充分体现人类对其驯化的历史过程。番茄是植物生物学和果实发育研究的重要模式物种之一,但是人类长期驯化对番茄基因组的影响仍是未知的。本研究通过对收集于世界各地360份番茄变异组的深入分析,鉴定了1160多万个S... 详细信息

植物基因组的变化能够充分体现人类对其驯化的历史过程。番茄是植物生物学和果实发育研究的重要模式物种之一,但是人类长期驯化对番茄基因组的影响仍是未知的。本研究通过对收集于世界各地360份番茄变异组的深入分析,鉴定了1160多万个SNPs变异位点,获得了该作物最全面的遗传变异图谱。基于番茄系统发生树的构建和群体结构分析,发现番茄群体分为3个亚群,即醋栗番茄、樱桃番茄和普通栽培番茄,提出了醋栗番茄经过樱桃番茄最终驯化为大果栽培番茄的两步驯化(Domestication and Improvement)理论。通过番茄遗传多样性分析,发现了5个单果质量QTL属于驯化阶段选择基因,1 3个单果质量QTL属于改良阶段选择基因。通过加工番茄和鲜食番茄的群体分化分析,发现了含有控制可溶性固形物和果实硬度的QTLs位点。利用全基因组关联分析(GwAS),鉴定了控制番茄果皮颜色的关键变异位点,为番茄品质育种提供了基因组数据支撑。现代育种中野生抗病基因被广泛应用到栽培番茄中,研究发现R基因的利用导致了大片段的外源渗入(例如:Tm-2,Chr.9,≈50 Mb),导致了严重的连锁累赘。全面分析了番茄的群体结构、遗传多样性、基因组进化历程和群体分化等最基本的生物学命题,提出栽培番茄是经过驯化和改良两个历史过程形成,为番茄生物学研究、基因克隆及遗传改良等提供理论指导。

关键词：番茄基因组驯化改良群体遗传

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欧洲中央银行（ECB）

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城市环境设计 2020年第4期 162-173页

作者：沃尔夫·狄·普瑞克斯 Magdalena Baczkowska Markus Baumann Michael Beckert Johannes Behrens hilde Benda Marcelo Bernardi Nico Boyer Jan Brosch Timo Carl Anna Rita Cedroni Jasmin Dieterle Sabrina Dlugosch Jan Ruben Fischer Brigitte Fuchs Sergio Gonzales Gesine G?rlich Martin Gruber Guthu hallstein Sebastian haffner Simone hainz Sascha hempel Rob henderson Emanuele Iacono Martin Jelinek Rashmi Krishna Jois Ivana Jug Frank Pascal Kaul Matt Kirkham Daniela Kr?hnert Bernward Krone Christian Labud Anke Lammert Monika Lyzyczka Steven M Christian Maeder Dimitra Mamou Ariane Marx Christoph Maurer Matthias Niemeyer Martin Oberascher Ross Olson Renate Ott Gerhard Pfeiler Ellen Pietrzyk james Pike Robert Pippan Jakob Przybylo Anna Ptaszynska Stephanie Rathgeber Carmen Renz Salome Reves Donna Riedel Akvile Rimantaite Pete Rose Penelope Rüttimann Stefan Rutzinger Oliver Sachse Kristina Schinegger Benjamin Schmidt Marita Schnepper Thomas Siegl Ebru Simsek-Lenk Denise Sokolowski Augustin Solorzano Anja Sorger Andrea St?llenwerk Ernst Stockinger Crystal K.h Tang Jürgen Tiltmann Markus Tritthart Josef Tr?ster Günther weber Andreas weissenbach Clemens werb Judith werkh?user Markus wings Eva wolf Barbara Zeleny Thomas Zengger Zeyneb Badur Fabien Barthelemey Oliver Cassik Alejandro Corena Alexander Daxb?ck Mario Dign?ss helmut Fr?tscher Annegret haider Christian halm Gregor Kassl Gernot K?fer Alexander Laber Anita Lischka Rangel Malinov Oliver Martinz Philipp Munz Barbara Roller Nicole Rumpler wolfgang Ruthensteiner Stefan Salchinger Stefan Schadenb?ck Thomas Schwed hannes Schwed Eckart Schwerdtfeger Sylvia Spernbauer Christoph Treberspurg Johannes weigl Paul Raftery European Central Bank/RobertMetsch Markus Pillhofer

项目大事记/ChRONOLOGY竞赛/Competition:第一阶段/Phase 1:2003;第二阶段/Phase 2:2003-2004;修改阶段/Revision Phase:2004;优化阶段/Optimization Phase:2005规划设计起始时间/Start of Planning:2005前期工程/Preliminary Site works:2008主体施工/Main Construction works:2010竣工/Completion:2014项目参数/PROJECT DATA用地面积/Site Area:120 000m2建筑毛面积/Gross Floor Area:185 000m2

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