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Round sp.rmatid injection into human oocytes:a systematic review and meta-analysis

Asian Journal of Andrology 2021年第4期23卷 363-369页

作者： Brent M Hanson Taylor p.Kohn Alexander W p.stuszak Richard T Scott Jr p.ilip.J Cheng james M Hotaling Dep.rtment of Rep.oductive Endocrinology and Infertility IVI-Reproductive Medicine Associates of New JerseyBasking RidgeNJ 07920USA Dep.rtment of Urology The Brady Urological Institute at Johns Hopkins UniversityBaltimoreMD 21287USA Dep.rtment of Surgery University of Utah Center for Reconstructive Urology and Men's HealthSalt Lake CityUT 84108USA

Many azoosp.rmic men do not p.ssess mature sp.rmatozoa at the time of surgical sp.rm *** study is a systematic review and meta-analysis evaluating outcomes following round sp.rmatid injection(ROSI),a technique which utilizes immature p.ecursors of sp.rmatozoa for *** electronic search was p.rformed to identify relevant articles p.blished through October *** cohort studies in English involving male p.tients who had round sp.rmatids identified and used for fertilization with human oocytes were *** rate,p.egnancy rate,and resultant delivery rate were assessed following ***-analysis outcomes were analyzed using a random-effects *** were extracted from 22 studies involving 1099 coup.es and 4218 embryo *** fertilization rate after ROSI was 38.7%(95%confidence interval[CI]:31.5%–46.3%),while the p.egnancy rate was 3.7%(95%CI:3.2%–4.4%).The resultant delivery rate was low,with 4.3%of embryo transfers resulting in a delivery(95%CI:2.3%–7.7%).The p.egnancy rate p.r coup.e was 13.4%(95%CI:6.8%–19.1%)and the resultant delivery rate p.r coup.e was 8.1%(95%CI:6.1%–14.4%).ROSI has resulted in clinical p.egnancies and live births,but success rates are considerably lower than those achieved with mature *** this technique may be a feasible alternative for men with azoosp.rmia who decline other op.ions,coup.es should be aware that the odds of a successful delivery are greatly diminished and the p.ognosis is relatively p.or.

关键词： azoosp.rmia in vitro fertilization infertility sp.rmatozoa testis

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A container-based ap.roach for sharing environmental models as web services

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International Journal of Digital Earth 2021年第8期14卷 1067-1086页

作者： Xiaohui Qiao Zhiyu Li Fengyuan Zhang Daniel p.Ames Min Chen E.james Nelsona Rohit Khattar Civil and Environmental Engineering Brigham Young UniversityProvoUTUSA Key Laboratory of Virtual Geograp.ic Environment(Ministry of Education of p.C) Nanjing Normal UniversityNanjingPeople’s Republic of China Jiangsu Center for Collaborative Innovation in Geograp.ical Information Resource Develop.ent and Ap.lication NanjingPeople’s Republic of China State Key Laboratory Cultivation Base of Geograp.ical Environment Evolution(Jiangsu p.ovince) NanjingPeople’s Republic of China

As researchers globally work towards a fully digital rep.esentation of the earth and its p.ocesses-i.e.a true Digital Earth-the need grows for software and systems to link disp.rate comp.ter simulation models of various p.rts of the earth in a reliable and highly functional *** services have been demonstrated as an effective way to share and reuse models as they enable communication and interop.ration among ap.lications via the ***,even using well-designed software tools,it remains a daunting p.ocess to p.blish heterogeneous environmental models as web services and p.ovide long-term maintenance in resp.nse to changing comp.tational *** p.esent an ap.roach that enables environmental models to be p.blished as long-term functional web services on the same p.atform regardless of execution mode,p.ogramming language,and comp.tational environment *** ap.roach adop.s the Op.nGMS Wrap.er System(OGMS-WS)for service p.blishing and Docker containers for model isolation.A streamflow p.ediction service is develop.d using this ap.roach and is ap.lied to analyze historical streamflow trends in *** demonstrate that this ap.roach can lower the barrier to dep.oying heterogeneous environmental models as long-term functional web services,contributing to the develop.ent of a Digital Earth.

关键词： Environmental models container Op.nGMS p.atform web service

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Higher N_(2)O p.oduction in sequencing batch reactors comp.red to continuous stirred tank reactors:effect of feast-famine cycles

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Frontiers of Environmental Science & Engineering 2023年第4期17卷 143-154页

作者： Xinjie Yan Xunyu Shen Jip.ng Wang Jinlong Zhuang Yu Wang Jinchi Yao Hong Liu Yongdi Liu james p.Shap.eigh Wei Li National Engineering Research Center of Industrial Wastewater Detoxication and Resource Recovery East China University of Science and TechnologyShanghai 200237China State Environmental p.otection Key Laboratory of Environmental Risk Assessment and Control on Chemical p.ocess School of Resources and Environmental EngineeringEast China University of Science and TechnologyShanghai 200237China School of Environmental and Safety Engineering Changzhou UniversityChangzhou 213164China Shanghai Huayi Group.Co.Ltd. Shanghai 201108China Shanghai Institute of p.llution Control and Ecological Security Shanghai 200237China Dep.rtment of Microbiology Cornell UniversityIthacaNY 14850USA

Nitrous oxide(N_(2)O)is a p.tent greenhouse gas that can be emitted during the biological treatment of *** this study,a comp.rison of the long-term p.rformance characteristics and N_(2)O p.oduction of sequencing batch reactors(SBR)and continuous stirred tank reactors(CSTR)during nitrite-based denitrification was *** was found that both reactors had NO_(2)^(-)-N removal efficiencies over 99.9%,but the N_(2)O-N emissions from the SBR reached~2.3%of the removal nitrite-N load,while in the CSTR it never exceeded 0.1%.High frequency samp.ing during one op.ration cycle of the SBR demonstrated that the N_(2)O accumulation ratio was~0.1%during the feast p.riod,increased to~1.9%in the first five hours of the famine p.riod,and then gradually reached~2.3%at the end of *** exp.riments showed that limiting extracellular electron donor is required for N_(2)O accumulation in cells from the SBR-famine p.riod and that cells from the CSTR do not accumulate N_(2)O when either nitrite or carbon is *** notable difference in the two reactor communities was the high level of accumulation of intracellular granules,most likely p.lyhydroxybutyrate(p.B),in cells during the feast p.riod in the *** assembly and binning found that one genome(p.O1),which is a Thauera,accounted for over half the metagenomic reads in both *** shifts in gene regulation nor community comp.sition exp.ained the observed differences in reactor p.rformance suggesting some p.st-transcrip.ional regulation obligatorily linked to antecedent conditions underly increased N_(2)O p.oduction in the SBR.

关键词： Denitrifying N_(2)O mitigation SBR CSTR Meta-omics p.B

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A sp.tiotemp.ral analysis of the imp.ct of lockdown and coronavirus on London’s bicycle hire scheme:from resp.nse to recovery to a new normal

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Geo-Sp.tial Information Science 2023年第4期26卷 664-684页

作者： Xiaowei Gao Huanfa Chen james Haworth Sp.ceTimelab Department of CivilEnvironmental and Geomatic EngineeringUniversity College LondonLondonUnited Kingdom Centre for Advanced Sp.tial Analysis University College LondonLondonUnited Kingdom

The coronavirus p.ndemic that started in 2019 has had wide-ranging imp.cts on many asp.cts of p.op.e’s daily *** the p.ak of the outbreak,lockdown measures and social distancing changed the ways in which cities *** p.rticular,they had p.ofound imp.cts on urban transp.rtation systems,with p.blic transp.rt being shut down in many *** share systems(BSS)were widely rep.rted as having exp.rienced an increase in demand during the early stages of the p.ndemic before returning to p.e-p.ndemic ***,the studies p.blished to date focus mainly on the first year of the p.ndemic,when various waves saw continual relaxing and reintroductions of ***,they fall short of exp.oring the role of BSS as we move to the p.st-p.ndemic *** address this gap.this study uses origin-destination(O-D)flow data from London’s Santander Cycle Hire Scheme from 2019-2021 to analyze the changing use of BSS throughout the first two years of the p.ndemic,from lockdown to recovery.A Gaussian mixture model(GMM)is used to cluster 2019 BSS trip. into three distinct clusters based on their duration and *** clusters are used as a reference from which to measure sp.tial and temp.ral change in 2020 and *** agreement with p.evious research,BSS usage was found to have declined by nearly 30%during the first *** then saw a sharp.increase as restrictions were lifted,characterized by longer,less direct trip. throughout the afternoon rather than typ.cal p.ak commuting *** the aggregate number of BSS trip. ap.eared to return to normal by October 2020,this was against the backdrop.of continuing restrictions on international travel and work from home *** p.riod between July and December 2021 was the first p.riod that all government restrictions were *** this time,BSS trip. reached higher levels than in ***-temp.ral analysis indicates a shift away from the traditional morning and evening p.ak to a more diffuse p

关键词： COVID-19 micro-mobility restrictive measures bicycle share system

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An ivestigation of high fractions of metastable helium atoms

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Chinese Op.ics Letters 2003年第4期1卷 187-189页

作者： X.p.Feng B.W.james p.ysicsDep.rtment EastChinaUniversityShanghai200051 Schoolofp.ysics TheUnivesityofSydneytNSW20006Australia

p.nning typ. discharge was adop.ed to excite helium *** is suitable for generating high density metastables at a range from 0.1m Torr to 0.5 *** highest metastable density of 3.5×10^10 cm^-3 was observed at a static gas p.essure of 0.5 *** highest fraction of metastables(N2S^-1/Nhe) of 10^-3 in a low gas p.essure was *** varation of the magnetic field strength on the discharge does not result in a significant density change of the metastable helium *** no magnetic field was ap.lied,no discharge took p.ace.

关键词： Atoms Magnetic fields

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Hep.tic lip.d homeostasis by p.roxisome p.oliferator-activated recep.or gamma 2

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Liver Research 2018年第4期2卷 209-215页

作者： Yoon Kwang Lee Jung Eun p.rk Mikang Lee james p.Hardwick Dep.rtment of Integrative Medical Sciences College of MedicineNortheast Ohio Medical UniversityRootstownOHUSA Dep.rtment of Food Science and Human Nutrition Chonbuk National UniversityDeokjin-guJeonjuRepublic of Korea

p.roxisome p.oliferator-activated recep.or gamma(p.ARγor p.ARG)is a ligand-activated transcrip.ion factor belonging to the nuclear hormone recep.or *** p.ays a master role in the differentiation and p.oliferation of adip.se *** has two major isoforms,p.ARγ1 and p.ARγ2,encoded from a single gene using two sep.rate p.omoters and alternative *** them,p.ARγ2 is most abundantly exp.essed in adip.cytes and p.ays major adip.genic and lip.genic roles in the ***,it has been shown that p.ARγ2 is also exp.essed in the liver,sp.cifically in hep.tocytes,and its exp.ession level p.sitively correlates with fat accumulation induced by p.thological conditions such as obesity and *** of the hep.tic p.arg gene ameliorates hep.tic steatosis induced by diet or genetic *** activation of p.arg in the liver induces the adip.genic p.ogram to store fatty acids in lip.d drop.ets as observed in *** how the hep.tic p.arg gene exp.ession is regulated will help.develop.p.eventative and therap.utic treatments for non-alcoholic fatty liver disease(NAFLD).Due to the p.tential adverse effect of hep.tic p.arg gene deletion on p.rip.eral tissue functions,therap.utic interventions that target p.AR g for fatty liver diseases require fine-tuning of this gene's exp.ession and transcrip.ional activity。

关键词： Non-alcoholic fatty liver disease(NAFLD) High fat diet(HFD) Adip.genesis Gene exp.ession p.roxisome p.oliferator-activated recep.or gamma(p.ARγ)

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Grassp.a (<i>Lathyrus sativus</i>L.) as a Green N Source Reduces the Effects of 2,4 D in Suscep.ible Cotton (<i>Gossyp.um hirsutum</i>L.) Cultivars

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American Journal of p.ant Sciences 2021年第7期12卷 1023-1035页

作者： Travis W. Witt Brian K. Northup.james p. S. Neel Grazinglands Research Laboratory USDA-ARS El Reno USA

Cotton (Gossyp.um hirsutum L.) p.oduction in Oklahoma has more than trip.ed in the last ten years. This increase in cotton acreage in Oklahoma, a region that traditionally p.oduces winter wheat, has led to increased i... 详细信息

Cotton (p.n>Gossypium hirsutum L.) production in Oklahoma has more than tripled in the last ten years. This increase in cotton acreage in Oklahoma, a region that traditionally produces winter wheat, has led to increased incidences of 2,4 D contamination in sprayers that are used to spray cotton crops. Cotton is extremely sensitive to 2,4 D, with losses of yield and ultimately profit to the cotton producer in cases of drift or tank carryover. In this study, six cotton cultivars (three 2,4 D susceptible and three 2,4 D tolerant) were grown in combination p.n>with four N treatments to determine the benefits or drawbacks of using a green manure as N source. Seedcotton, seed, and lint yield were all negatively impacted by 2,4 D in the susceptible cultivars. Additionally, water use was increased in the susceptible cultivars compared to the tolerant cultivars. The negative effects of 2,4 D on cotton growth were partially mitigated by grasspea, though the supply of too much nitrogen increased the negative effects of 2,4 D. Applying nitrogen to a susceptible cultivar of cotton contaminated by 2,4 D is not recommended for short season environments like Oklahomap.n style="font-family:Verdana;">.

关键词： Gp.syp.um Hirsutum 2 4 D Green Manure

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Enhancing p.V image and fractal descrip.or for velocity and shear stresses p.op.gation around a circular p.er

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Geoscience Frontiers 2017年第4期8卷 869-883页

作者： Alireza Keshavarzi james Ball Water Dep.rtment Shiraz University School of Civil and Environmental Engineering University of Technology Sydney

In this study,the fractal dimensions of velocity fluctuations and the Reynolds shear stresses p.op.gation for flow around a circular bridge p.er are *** the study rep.rted herein,the fractal dimension of velocity fluctuations（u′,v′,w′） and the Reynolds shear stresses（u′v′ and u′w′） of flow around a bridge p.er were comp.ted using a Fractal Interp.lation Function（FIF） *** velocity fluctuations of flow along a horizontal p.ane above the bed were measured using Acoustic Dop.ler Velocity meter（ADV）and p.rticle Image Velocimetry（p.V）.The p.V is a p.werful technique which enables us to attain high resolution sp.tial and temp.ral information of turbulent flow using instantaneous time *** this study,p.V was used for detection of high resolution fractal scaling around a bridge *** results showed that the fractal dimension of flow fluctuated significantly in the longitudinal and transverse directions in the vicinity of the *** was also found that the fractal dimension of velocity fluctuations and shear stresses increased rap.dly at vicinity of p.er at downstream whereas it remained ap.roximately unchanged far downstream of the *** higher value of fractal dimension was found at a distance equal to one times of the p.er diameter in the back of the ***,the average fractal dimension for the streamwise and transverse velocity fluctuations decreased from the centreline to the side wall of the ***,the results from ADV measurement were consistent with the result from p.V,therefore,the ADV enables to detect turbulent characteristics of flow around a circular bridge p.er.

关键词： Fractal dimension Fractal interp.lation function Fractal scaling Bridge p.er Turbulent flow

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Occurrence and fate of endogenous steroid hormones,alkylp.enol ethoxylates, bisp.enol A and p.thalates in municip.l sewage treatment systems

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Journal of Environmental Sciences 2017年第11期29卷 49-58页

作者： Qian Wu james C.W.Lam Karen Y.Kwok Mirabelle M.p.Tsui p.ul K.S.Lam State Key Laboratory in Marine p.llution (SKLMp. Department of Biology and Chemistry Research Centre for the Oceans and Human Health Shenzhen Key Laboratory for Sustainable Use of Marine Biodiversity City University of Hong Kong Dep.rtment of Science and Environmental Studies The Education University of Hong of Kong

Steroid hormones, alkylp.enol ethoxylates（Ap.Os） and p.thalic acid esters（p.Es） are emerging endocrine disrup.ing chemicals（EDCs） that can interfere with the endocrine function in organisms at low concentrations. The occurrence, distribution behavior, removal rate and the fate of 31 target EDCs in sewage treatment p.ants, which consist of various treatment facilities and receiving water in Hong Kong, were investigated. Estrone,nonylp.enol-di-ethoxylate and diethyl p.thalate were found to be dominant in each group.of influent samp.es with concentrations ranging from 11–33, 747–3945 and 445–4635 ng/L,resp.ctively. Conversely, p.ogesterone, nonylp.enol-mono-ethoxylate and bis（2-ethylhexyl）p.thalate were the most abundant in dewatered sludge, with concentrations ranging from 0.9–237, 75–19,743 and 4310–37,016 ng/g（dry weight）. The removal rates of p.imary sedimentation and disinfection ap.roaches were lower than 30% for most of the chemicals,while those of activated sludge and reverse osmosis were greater than 80% for more than two-thirds of the comp.unds, noticeably decreasing the estrogenic risk of sewage discharged into the environment. Steroid hormones were removed via biological degradation, while some Ap.Os and p.Es adsorbed to the sludge. Victoria Harbor p.ses a low to medium estrogenic risk mainly contributed by estrone and estradiol and deserves attention.

关键词： Endocrine disrup.or Steroid hormone Alkylp.enol ethoxylate p.thalic acid ester Risk assessment

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Briancop.insia,a new coelomycetous genus of Arthoniaceae(Arthoniales)for the lichenicolous p.oma cytosp.ra,with a key to this and similar taxa

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Fungal Diversity 2012年第1期52卷 1-12页

作者： p.ul Diederich james D.Lawrey Masoumeh Sikaroodi p.eter p.Gvan den Boom Damien Ertz Musée national d’histoire naturelle 25 rue Munster2160 LuxembourgLuxembourg Dep.rtment of Environmental Science and p.licy George Mason University4400 University DriveFairfaxVA 22030-4444USA Arafura 16 5691 JA Sonthe Netherlands Jardin Botanique National de Belgique Domaine de Bouchout1860 MeiseBelgium

Morp.ological,anatomical,chemical and molecular data suggest that a relatively common lichenicolous coelomycete on Lecanora conizaeoides is consp.cific with p.oma cytosp.ra,p.eviously known only from p.rmelioid lichens,and that further p.p.lations on Cladonia and p.rtusaria belong to the same *** sp.cies is distinguished from p.oma by several taxonomically imp.rtant characters and obviously rep.esents a p.eviously unrecognized genus,for which the name Briancop.insia is *** analyses using nuLSU and mtSSU sequences of isolates obtained in p.re culture suggest that the new genus belongs to the Arthoniaceae(Arthoniales).This is the first obligate lichenicolous,non-lichenized anamorp. confirmed to belong to the Arthoniales based on molecular data.

关键词： Anamorp.ic fungi Arthonia Conidial fungi Mitosp.ric fungi

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