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Weak mismatch epitaxy and structural feedback in graphene growth on copper foil

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Nano Research 2013年第2期6卷 99-112页

作者： Neil R. Wilson alexander J. Marsden Mohammed Saghir Catherine J. Bromley Renald Schaub Giovanni Costantini Thomas W. White Cerianne Partridge Alexei Barinov Pavel Dudin Ana M. Sanchez james J. Mudd Marc Walker Gavin R. Bell Department of Physics University of Warwick Coventry CV4 7AL UK EaStCHEM School of Chemistry University of St Andrews St Andrews KY16 9ST UK Department of Chemistry University of Warwick Coventry CV4 7AL UK Sincrotrone Trieste S.Cp.A. Area Science Park 1-34012 Basovizza Trieste Italy

Graphene growth by low-pressure chemical vapor deposition on low cost copper foils shows great promise for large scale applications. It is known that the local crystallography of the foil influences the graphene growth rate. Here we find an epitaxial relationship between graphene and copper foil. Interfacial restructuring between graphene and copper drives the formation of （nl0） facets on what is otherwise a mostly Cu（100） surface, and the facets in turn influence the graphene orientations from the onset of growth. Angle resolved photoemission shows that the electronic structure of the graphene is decoupled from the copper indicating a weak interaction between them. Despite this, two preferred orientations of graphene are found, ±8° from the Cu[010] direction, creating a non-uniform distribution of graphene grain boundary misorientation angles. Comparison with the model system of graphene growth on single crystal Cu（110） indicates that this orientational alignment is due to mismatch epitaxy. Despite the differences in symmetry the orientation of the graphene is defined by that of the copper. We expect these observations to not only have importance for controlling and understanding the growth process for graphene on copper, but also to have wider implications for the growth of two-dimensional materials on low cost metal substrates.

关键词： graphene chemical vapordeposition mismatch epitaxy structural feedback low energy electrondiffraction angle resolvedphoto-emissionspectroscopy (ARPES)

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遇见下一个晴天

现代装饰（家居） 2014年第5期 36-43页

作者： Claro Pascoe alexander james 肖俊英国Pascoe Interiors

本案是位于伦敦离樱草山不远的奎克斯伍德街的一幢建于20世纪60年代的排屋。作为乌克兰外交官的业主和他的家人已在此居住多年。现在这栋住宅急待进行一次全面翻新和现代化改造，以提升空间整体的采光效果和空间感。在设计师Clare Pasco... 详细信息

本案是位于伦敦离樱草山不远的奎克斯伍德街的一幢建于20世纪60年代的排屋。作为乌克兰外交官的业主和他的家人已在此居住多年。现在这栋住宅急待进行一次全面翻新和现代化改造，以提升空间整体的采光效果和空间感。在设计师Clare Pascoe承担本案的室内设计之前，建筑设计团队AR Architecture首先对房屋的建筑结构进行了再设计，他们通过拆除多余的内墙，展现室内的错层式结构，一方面提升了内部空间的流动性，另一方面也使得住宅的朝北面的采光效果得到了进一步改善。

关键词：采光效果室内设计现代化改造建筑设计建筑结构层式结构内部空间空间感

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从天然提取物或分离部位中以碳酸酐酶II为靶点的抗骨质疏松活性筛选(英文)

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云南植物研究 2003年第6期25卷 724-729页

作者：付祥谭宁华姜立花贾锐锐嵇长久 LANDRO james FEKETE alexander MUELLER Hartwig HENKEL Thomas 中国科学院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室云南昆明650204 Bayer Corporation IRT Bayer AG PH-R-EU

目的是以碳酸酐酶II (CAII)为靶点筛选其抑制剂 ,以期寻找抗骨质疏松活性样品。实验是在 96孔酶标板上对来源于 1 78个科、 60 8个属、 1 0 2 0种动植物 2 91 9个提取物或分离部位样品在CA II模型上进行了批量筛选。结果表明在 1 0 μg... 详细信息

目的是以碳酸酐酶II (CAII)为靶点筛选其抑制剂 ,以期寻找抗骨质疏松活性样品。实验是在 96孔酶标板上对来源于 1 78个科、 60 8个属、 1 0 2 0种动植物 2 91 9个提取物或分离部位样品在CA II模型上进行了批量筛选。结果表明在 1 0 μg ml浓度下发现了来源于 40个科、61个属、72个种的 1 0 0个样品有活性 ,其中 5个样品的IC50 小于 2 50 μg ml,2 2个样品的IC50 在 2 51～ 5 0 0 μg ml范围 ,73个样品的IC50 在 5 0 1～1 0 0 0 μg ml范围。通过以上工作我们认为以碳酸酐酶II为分子靶点的体外筛选方法稳定、方便、快速、微量、有效 ,特别适用于天然产物的抗骨质疏松活性筛选。

关键词：抗骨质疏松活性筛选碳酸酐酶Ⅱ 天然产物提取物分离部位

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Robustness Evaluation of a Novel Proton Beam Geometry for Head and Neck Patients Treated with Pencil Beam Scanning Therapy

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International Journal of Medical Physics, Clinical Engineering and Radiation Oncology 2018年第3期7卷 308-322页

作者： Sheng Huang Haoyang Liu Jiajian Shen Huifang Zhai Maura Kirk Brett Hartl alexander Lin james McDonough Stefan Both Haibo Lin Department of Radiation Oncology University of Pennsylvania Philadelphia PA USA New York Proton Center New York NY USA New Jersey Proton Therapy Center Somerset NJ USA Mayo Clinic Phoenix AZ USA University Medical Center Groningen Groningen The Netherlands

Background: To evaluate the robustness of head and neck treatment using proton pencil beam scanning (PBS) technique with respect to range uncertainty (RU) and setup errors (SE), and to establish a robust PBS planning strategy for future treatment. Methods and Materials: Ten consecutive patients were planned with a novel proton field geometry (combination of two posterior oblique fields and one anterior field with gradient dose match) using single-field uniform dose (SFUD) planning technique and the proton plans were dosimetrically compared to two coplanar arc VMAT plans. Robustness of the plans, with respect to range uncertainties (RU = ± 3% for proton) and setup errors (SE = 2.25 mm for proton and VMAT), in terms of deviations to target coverage (CTV D98%) and OAR doses (max/mean), were evaluated and compared for each patient under worst case scenarios. Results: Dosimetrically, PBS plans provided better sparing to larynx (p = 0.005), oral cavity (p < 0.001) and contralateral parotid (p = 0.004) when compared to VMAT. CTV D98% variations were higher from SE than from RU for proton plans (-1.1% ± 1.3 % vs -0.4% ± 0.7% for nodal CTV and -1.4% ± 1.2 vs -0.4% ± 0.5% % for boost CTV). Overall, the magnitudes of variation of CTV D98% to combined SE and RU were found to be similar to the impact of the SE on the VMAT plans (-1.6% ± 1.9% vs -1.7% ± 1.4% for nodal CTV and -1.9% ± 1.6% vs -1.3% ± 1.5% for boost CTV). Compared to VMAT, a larger range of relative dose deviations were found for OARs in proton plans, but safe doses were maintained for cord (41.8 ± 3.6 Gy for PBS and 41.7 ± 3.9 Gy for VMAT) and brainstem (35.2 ± 8.4 Gy for PBS and 36.2 ± 5.1 Gy for VMAT) in worst case scenarios. Conclusions: Compared to VMAT, proton plans containing three SFUD fields with superior-inferior gradient dose matching had improved sparing to larynx, contralateral parotid and oral cavity, while providing similar robustness of target coverage. Evaluation of OAR dose robustness showed highe

关键词： Head and Neck Robustness Proton Therapy Pencil Beam Scanning

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碳在湿型砂中的作用

铸造 2010年第1期59卷 84-89页

作者： alexander Brown 刘金城 james Durrans Group based at Penistone

论述了原材料控制对于湿型砂铸件生产的重要性,阐述了碳质添加剂对铸件质量的影响,为了保证型砂质量的稳定,必须深入了解和控制型砂粒度、总碳量、挥发分和灼烧减量的关系。考察了各种预测和控制方法。强调了各种添加剂的性能及其作用... 详细信息

论述了原材料控制对于湿型砂铸件生产的重要性,阐述了碳质添加剂对铸件质量的影响,为了保证型砂质量的稳定,必须深入了解和控制型砂粒度、总碳量、挥发分和灼烧减量的关系。考察了各种预测和控制方法。强调了各种添加剂的性能及其作用以及它们的相互影响。对来料控制检测方法和加入混砂机的添加剂进行了讨论。对检测结果、控制操作和用湿型砂获得性能稳定,质量高的铸件需要采取的措施做了评述,强调要了解和控制碳质添加剂对铸件性能的影响。

关键词：煤粉膨润土湿型砂总碳挥发分

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Molecular Biology of the Gene 5th ed.

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2004年

作者： james D. Watson Tania A. Baker Stephen P. Bell alexander Gann Michael Levine Richard Losick

ISBN: (纸本)9780805346350

Every student package automatically includes a CD-ROM and access to a website containing tutorials, molecular models, and *** long-awaited Fifth Edition of james D. Watson's classic text, Molecular Biology of the Gene, has been thoroughly revised and is published to coincide with the 50th anniversary of Watson and Crick's paper on the structure of the DNA double- *** being completely updated, the new edition retains the distinctive character of earlier editions that made it the most widely used book in molecular biology. Twenty-one concise chapters, co-authored by five highly respected molecular biologists, provide current, authoritative coverage of a fast-changing discipline. The completely new art is printed in full colour for the first *** into four parts, the first (Genetics and Chemistry) begins with an overview of molecular biology, placing the discipline in historical context and introducing the basic chemical concepts that underpin our description of molecular biology today. The second part (Central Dogma) forms the heart of the book, describing in detail the basic mechanisms of molecular biology. The third part of the book (Regulation) deals with how gene expression is regulated - from the examination of basic mechanisms that regulate gene expression in bacterial and eukaryotic systems, to a description of how regulation of gene expression lies at the heart of the process of development. Recent findings from sequencing whole genomes of several animals have revealed that they all share essentially the same genes. The last chapter in the regulation section looks at how changes in gene regulation can account for how different animals can be made from the same genes. The final part of the book (Methods) deals with the techniques and methods used in molecular biology.[Contents]I. CHEMISTRY AND GENETICS.1. The Mendelian View of the World.2. Nucleic Acids Convey Genetic Information.3. The Importance of Weak Chemical Interactions.4. The Impo

关键词： Molecular biology.

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过筛煤粉在铸铁件湿型砂铸造生产中的作用

铸造 2011年第6期60卷 610-613页

作者： alexander Brown 向青春(译) james Durrans ＆ Sons Ltd Phoenix WorksPenistoneSheffieldEngland S369QU 不详

正确选择煤粉,其性能要求同时具有低灰分、高挥发分和高膨胀指数,以及具有合适的筛分粒度这一关键因素,以确保所生产的铸件没有机械粘砂缺陷和表面质量问题。通过仔细选择、安全操作和加工处理,煤粉仍然是一个优良的、简易的、经济的有... 详细信息

正确选择煤粉,其性能要求同时具有低灰分、高挥发分和高膨胀指数,以及具有合适的筛分粒度这一关键因素,以确保所生产的铸件没有机械粘砂缺陷和表面质量问题。通过仔细选择、安全操作和加工处理,煤粉仍然是一个优良的、简易的、经济的有效解决方案。煤粉在储存、加工和运输过程中易于调节,然后经过进一步的安全处理,最终被铸造厂使用。尽管煤粉有诸多不足之处,对于最终用户来说,它仍然是经济合算的。而且现代加工和筛分方法确保它在最佳条件下使用。

关键词：过筛煤粉铸铁件湿型砂生产

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Physical Characteristics Explain Ball-Carrying Capability in Sub-Elite Rugby Union Players

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Journal of Science in Sport and Exercise 2023年第3期5卷 244-253页

作者： alexander S.Hart Robert M.Erskine Tom J.Mclaughlin David R.Clark School of Sport and Exercise Science Liverpool John Moores UniversityL33AF LiverpoolUK Ealing Trailfinders Rugby Club LondonUK Institute of Sport Exercise and HealthUniversity College LondonLondonUK

Purpose The aims of the present study were two-fold:(i)to investigate the relationship between physical characteristics and the game statistics associated with ball-carrying capability amongst sub-elite rugby union players,and(ii)to predict the level of change in these physical characteristics required to improve the associated game statistic via regression *** Thirty-eight senior professional players(forwards,n=22;backs,n=16)were assessed for body mass(BM),back squat(BS)single-repetition maximum(1RM)normalised to BM(1RM/BM),10 m sprint velocity(S10),10 m sprint momentum(SM10),and the game statistics from 22 games within the 2019/20 RFU Championship *** relationship between these measures and the predicted level of change in a physical measure required to improve the total number of the associated game statistic by one were assessed by pearson’s correlation coefficient and simple regression *** In forwards,an~11.5%reduction in BM,an~11.8%improvement in BS 1RM/BM,or an~11.5%increase in S10 was required to improve the game statistics associated with ball-carrying *** backs,a~19.3%increase in BM or a~15.6%improvement in SM10 was *** These findings demonstrate that improvements in lower-body relative strength,acceleration performance,and position-specific alterations in body mass are required to maximise the ball-carrying capability and therefore match outcome of sub-elite rugby union players.

关键词： Speed Acceleration Momentum Strength Body mass

Is Anticoagulation Warranted after Left Atrial Appendage Ligation in Patients at Risk for Stroke after Cardiac Surgery?

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World Journal of Cardiovascular Surgery 2023年第2期13卷 26-43页

作者： alexander P. Kossar Yaagnik D. Kosuri Samantha Nemeth Brigitte E. Kazzi Yuming Ning james Doolittle Denise McLaughlin Paul Kurlansky Isaac George Division of Cardiothoracic Surgery New-York Presbyterian Hospital/Columbia University Irving Medical Center New York USA Columbia HeartSource Center for Innovation and Outcomes Research Columbia University Irving Medical Center New York USA

Objectives: Left atrial appendage ligation (LAAL) may constitute alternative stroke prophylaxis in patients with atrial fibrillation (AF). Herein we describe the 30-day post discharge outcomes of cardiac surgery patients with elevated stroke risk with or without anticoagulation (AC) following epicardial LAAL. Methods: Data were reviewed for 479 consecutive adult patients who underwent epicardial LAAL from 2014-2019 (median CHA2DS2-VASc score = 4.0). There were 251 and 228 patients discharged with and without AC, respectively, who were followed for 30 days. Patients were matched via 1:1 Propensity Score Matching (PSM;n = 115 per group). Post-discharge outcomes included stroke, bleeding, readmission for cardiac re-intervention, mortality, and a composite endpoint comprised of the aforementioned outcomes. Results: There was no difference in post-discharge stroke incidence regardless of AC (adjusted cumulative incidence (ACI) 0.009 CI [0.001 - 0.043] with AC vs 0.009 CI [0.001 - 0.43] without AC;p = 0.826), post-discharge bleeding (ACI 0.018 CI [0.003 - 0.057] with AC vs 0.009 CI [0.001 - 0.046] without AC;p = 0.738), readmission for cardiac re-intervention (ACI 0.009 CI [0.009 - 0.009] with AC vs 0 CI [NA] without AC;p = 0.340, post-discharge mortality (ACI 0 CI NA with AC vs 0.009 CI [0.001 - 0.046] without AC;p = 0.123, or in the composite outcome (ACI 0.026 CI [0.007 - 0.069] with AC vs 0.027 CI [0.007 - 0.071] without AC;p = 0.824. Conclusion: Cessation of AC in patients with elevated stroke risk following epicardial LAAL during cardiac surgery does not affect stroke rate, mortality, or bleeding incidence up to 30 days post-discharge in this preliminary analysis.

关键词： Arrhythmias Minimally Invasive Surgery Perioperative Care