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Composition analysis and antimicrobial activity of essential oil from leaves of Laurus nobilis grown in Oman

Journal of Bioresources and Bioproducts 2022年第4期7卷 328-334页

作者： Siham Saleh al-Abri Sadri Abdullah Said Salem Said al Touby Mohammed Amzad Hossain jamal nasser al-sabahi School of Pharmacy College of Pharmacy and NursingUniversity of NizwaPB 33PO 616NizwaNizwa 616Oman School of Nursing College of Pharmacy and NursingUniversity of NizwaNizwa 616Oman Central Instrument Laboratory College of Agriculture and Marine SciencesSultan Qaboos UniversityMuscat 123Oman

Traditionally,Laurus nobilis is used for the treatment of earaches and skin rashes as well as *** most common technique to isolate the oil is hydro-distillation and *** investigation presented in this paper was aimed to unravel the antimicrobial activity and chemical composition of essential oil in the leaves of *** grown in *** essential oil was extracted from the leave of the selected plant species by hydro distillation using Clevenger type *** antimicrobial assay was done by disc diffusion methods against three bac-terial strains,Staphylococcus aureus,Pseudomonas aeruginosa and Escherichia coli,and one fungal strain:Candida *** isolated essential oil was analyzed by gas chromatography-mass spectrometry(GC-MS).The percentage yield of the essential oil was 0.064%(w/w).The essen-tial oil was found actively against the applied bacterial and fungal *** highest activity was found against *** and the lowest was against ***,and the order was ***>***>*** essential oil was also active against the fungus *** range of inhibition zones was 6-14 *** results of GC-MS analysis showed(E)-𝛽-caryophyllene to be the major component about 59.62%.Other major components included𝛼-selinene(14.03%),𝛼-humulene(8.65%),𝛽-selinene(4.99%),and𝛼-pinene(4.98%).In addition,several minor com-ponents were found in the essential oil of *** on the experimental results,it showed that the plant species that grown in Oman were a potential source of therapeutic *** con-clusion,the essential oil and the plant could be used as natural and potential therapeutic agents to treat earaches,skin rashes,and rheumatism.

关键词： Laurus nobilis Clevenger apparatus Essential oil Antimicrobial activity Gas chromatography-mass spectrometry(GC-MS)

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Gas chromatography-mass spectrometry analysis of different organic crude extracts from the local medicinal plant of Thymus vulgaris L

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Asian Pacific Journal of Tropical Biomedicine 2013年第1期3卷 69-73页

作者： Laila Salim al Hashmi Mohammad Amzad Hossain Afaf Mohammed Weli Qasim al-Riyami jamal nasser al-sabahi School of Pharmacy College of Pharmacy and NursingUniversity of NizwaP.0.Box 33Postal Code 616NizwaSultanate of Oman Central Instrument Laboratory College of Agriculture and Marine SciencesSultan Qaboos UniversitySultanate of Oman

Objective:To isolate and analyze the chemical composition in different crude extracts of from the leaves of locally grown of Thymus vulgaris L(***)by gas chromatography-mass spectrometry(GC-MS).Methods:The shade dried leaves powder was extracted with methanol by using Soxhlet *** crude extracts of *** and the derived fractions of hexane,chloroform,ethyl acetate and butanol were ***:Qualitative analyses of various organic crude extracts of *** by using GC-MS showed that there were different types of high and low molecular weight *** of the isolated and identified compounds by GC-MS in the crude extracts are basically biologically ***,the *** leaf possessed certain characteristics that can be ascribed to cultivation on a domestic *** crude extracts were prepared from the powder leaves of *** for respective compounds can be chosen on the basis of above GC-MS ***:all the major compounds were identified and characterized by spectroscopic method in different organic crude extracts of *** are biologically active *** the identification of a good number of compounds in various crude extracts of *** might have some ecological role.

关键词： Thymus vulgaris L Preparation crude extracts Soxhlet extractor GC-MS analyses

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Chemical composition of essential oils and in vitro antioxidant activity of fresh and dry leaves crude extracts of medicinal plant of Lactuca Sativa *** to sultanate of Oman

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Asian Pacific Journal of Tropical Biomedicine 2013年第5期3卷 353-357页

作者： Rahma Said Salim al Nomaani Mohammad Amzad Hossain Afaf Mohammed Weli Qasim al-Riyami jamal nasser al-sabahi School of Pharmacy College of Pharmacy and NursingUniversity of Nizwa Central Instrument Laboratory College of Agriculture and Marine SciencesSultan Qaboos University

Objective:To isolate and analyse the chemical composition in the essential oils and free radical scavenging activity of different crude extracts from the fresh and dry leaves of vegetable plants of Lactuca sativa L.(***).Methods:The essential oils and volatile chemical constituents were isolated from the fresh and dry leaves of ***(lettuce)grown in Sultanate of Oman by hydro distillation *** antioxidant activity of the crude extracts was carried out by well established free radical scavenging activity(DPPH)***:About 20 chemical compounds of different concentration representing 83.07%and 79.88%respectively were isolated and identified by gas chromatography-mass spectroscopy in the essential oils isolated from the fresh and dry leaves asα-pinene(5.11%and 4.05%).γ-cymene(2.07%and 1.92%),thymol(11.55%and 10.73%),durenol(52.00%and 49.79%),α-terpinene(1.66%and 1.34%),thymol acetate(0.99%and 0.67%),caryophyllene(2.11%and 1.98%),spathulenol(3.09%and 2.98%).camphene(4.11%and3.65%),limonene(1.28%and 1.11%)representing these major chemical ***,some other minor chemical constituents were also isolated and identified from the essential oil of lettuce including p-pinene,α-terpinolene,linalool,4-terpineol,α-terpineol,o-methylthymol,L-alloaromadendrene and ***:The chemical consliluents in the essential oils from the locally grown lettuce were identified in the following classes or groups of chemical compounds such as monoterpenes,sesquiterpenes volatile organic compounds and their oxygenated ***,the essential oils and the crude extracts from Omani vegetable species of lettuce are active candidates which would be used as antioxidant,antifungal or antimicrobial agents in new drugs preparation for therapy of infectious diseases.

关键词： Lactuca saliva Omani lettuce Clevenger apparatus Essential oil Durenol Thymol Soxhlet extractor Organic crude extracts Antioxidant activity GC-MS analyses

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Studies on free-radical scavenging activity and identification of active ingredients of different plant crude extracts of Mentha piperita collected from Sur,Sultanate of Oman

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Journal of Coastal Life Medicine 2014年第10期 805-810页

作者： Mohammad Amzad Hossain Aqeela Said Hamed al Orimi Afaf Mohammed Weli Qasim al-Riyami jamal nasser al-sabahi School of Pharmacy College of Pharmacy and NursingUniversity of NizwaP.O.Box 33Postal Code 616NizwaSultanate of Oman Central Instrument Laboratory College of Agricultural and Marine SciencesSultan Qaboos UniversitySultanate of Oman

Objective:To determine free radical scavenging activity and active chemical ingredients of different plant crude extracts of Mentha piperita(***).Methods:The dried powder leaves of *** were extracted with polar organic solvent by Soxhlet *** crude extract and its fractions of hexane,chloroform,ethyl acetate and butanol crude extracts were *** antioxidant activity of different crude extracts from *** was carried out by DPPH method with minor modification,and the active chemical ingredients of different plant crude extracts of *** were analyzed by gas chromatography-mass spectrometry(GC-MS).Results:Qualitative analysis of different polarities crude extracts by GC-MS found different types of active organic *** antioxidant activity of different crude extracts were found to be in the order of chloroform extract>butanol extract>ethyl acetate extract>hexane extract>methanol *** identified compounds in the plant crude extracts by GC-MS were biologically ***:Therefore,the isolation,purification,identification and characterization of bioactive compounds from various crude extracts of *** might have ecological significance.

关键词： Mentha piperita Lamiaceae Crude extracts Antioxidant activity DPPH Gas chromatography-mass spectrometry analysis

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Efficiency of combining pomegranate juice with low-doses of cisplatin and taxotere on A549 human lung adenocarcinoma cells

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Asian Pacific Journal of Tropical Biomedicine 2018年第1期8卷 19-24页

作者： nasser Mohamad Hijazi Akram Sayed Ahmad Bouchra jamal Eddine Zeinab Ibrahim Sajida Rammal Hassan al Rekaby Abd-El-Ameer nasser Mouhamad Doctoral School of Science and Technology Research Platform for Environmental Science (PRASE) Lebanese University Université Fédérale de Toulouse Midi-Pyrénées INP-ENSIACET Laboratoire de Chimie Agro-industrielle al Mustansiriya University College of Science Department of Biology American University of Beirut

Objective: To test the coalescence effect of two chemotherapy drugs at low effective dose(cisplatin and taxotere) combined with pomegranate juice on A549 cancer cells. Methods: Infrared spectroscopy method is a qualitative test that was performed to ensure the existence of the phytochemicals providing the antioxidant activity through the presence of the hydroxyl group(-OH). The viability of A549 cell line and normal MCs was tested using the neutral red uptake, Clonogenic survival, XTT and Cell migration assays. Results: Our results showed that this combination firstly led to a greater decrease in the viability of cells comparing to those treated with chemotherapy drugs alone, and secondly led to a significant reduction in cell migration. Conclusions: These data suggest a synergistic effect between the pomegranate and cisplatin which makes probably this combination a powerful option for treating lung adenocarcinoma and in parallel minimizing the systemic side effects.

关键词： Lung cancer Chemotherapy Cisplatin Taxotere Pomegranate A549 cells

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Experimental Investigation of Drilling Fluid Performance as Nanoparticles

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World Journal of Nano Science and Engineering 2013年第3期3卷 57-61页

作者： jamal nasser Anna Jesil Tariq Mohiuddin Majid al Ruqeshi Geetha Devi Shahjahan Mohataram Mechanical & Industrial Engineering Department Caledonian College of Engineering Muscat Oman Sultan Qaboos University Al khoudh Oman

In this work, a drilling fluid recipe has been developed by using nanoparticles, to increase the efficiency of drilling operations for maximum accessibility to new & matured oil reserves and suited to various drilling conditions. The solution to severe drilling problems like pipe sticking, lost circulation, formation damage, erosion of borehole, thermal instability of drilling fluids and insufficient gel properties of the drilling fluids, lies in controlling and optimizing the rheology of the drilling fluid. The inefficiency of the drilling fluid in performing certain functions is mainly due to a lack in a particular rheological property. The performance of the clay composites water-based bentonite drilling mud in terms of its rheological behavior in drilling systems was investigated at various pressures and temperatures. It was found that temperature had a detrimental effect on the rheological properties. The behavior was investigated using synthesized nano bentonite water based drilling fluid. The fluid retained all the desired rheological properties at elevated temperatures and pressures, thus enhanced the possibility of its application in deep wells, where elevated temperatures and pressures were quite common.

关键词： Drilling Fluid Nanoparticles Mud Viscosity Density

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Characteristics of common solid liver lesions and recommendations for diagnostic workup

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World Journal of Gastroenterology 2009年第26期15卷 3217-3227页

作者： Nimer Assy Gattas nasser Agness Djibre Zaza Beniashvili Saad Elias jamal Zidan Liver Unit Ziv Medical Center Faculty of Medicine Technion Institute of Technology Department of Medicine Western Galilee Hospital Department of Medicine Ziv Medical Center Institute of Oncology Ziv Medical Center

Due to the widespread clinical use of imaging modalities such as ultrasonography,computed tomography and magnetic resonance imaging (MRI),previously unsuspected liver masses are increasingly being found in asymptomatic *** review discusses the various characteristics of the most common solid liver lesions and recommends a practical approach for diagnostic *** diagnoses include hepatocellular carcinoma (the most likely;a solid liver lesion in a cirrhotic liver) and hemangioma (generally presenting as a mass in a non-cirrhotic liver).Focal nodular hyperplasia and hepatic adenoma should be ruled out in young *** 70% of cases,MRI with gadolinium differentiates between these *** needle core biopsy or aspiration,or both,might be required in doubtful *** uncertainty persists as to the nature of the lesion,surgical resection is *** the patient is known to have a primary malignancy and the lesion was found at tumor staging or follow up,histology is required only when the nature of the liver lesion is doubtful.

关键词： Liver mass Hepatic nodule Tumor Lesion Cirrhosis Hepatocellular carcinoma Magnetic resonance imaging Ultrasonography Computed tomography Fineneedle aspiration Biopsy

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The Clinical Presentations and Patterns of Management of Bowel Obstruction in Northern Saudi Arabia

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Surgical Science 2018年第5期9卷 174-181页

作者： Abdullah Fahad al Gharbi Muhannad Saud A. al Shammari jamal Ahmed A. al Marshadi Muteb nasser al Awad Abdulkarim ali al Qufayi Hamoud Khalid al Shaya Hussain Gadelkarim Ahmed College of Medicine University of Hail Hail Saudi Arabia

Background: The prompt management of patients with bowel obstruction is essential and requires initial rapid diagnosis and therapeutic intervention. Therefore, the objective of the present study was to explore the clinical presentation and pattern of management of bowel obstruction in Northern Saudi Arabia. Methodology: About 92 files referring to patients presented with obstructive bowel conditions during the period from 2013 to 2017 were retrieved from department of surgery at King Khalid Hospital, Hail, Northern Saudi Arabia. Results: Most of cases of bowel obstruction were found in 2014, followed by 2013, 2016, 2015, and 2017 constituting 22, 20, 20, 15, and 15 cases, respectively. About 76, 52, 69, 58, 13, and 28 of the patients presented with pain, constipation, vomiting, abdominal distention, bowel sound and accompanied disease, respectively. Conclusion: Laparotomy was the most common methods of bowel obstruction management in Northern Saudi Arabia. Many patients with bowel obstruction symptoms can improve without surgical intervention.

关键词： Bowel Obstruction Saudi Arabia Laparotomy

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