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Agmatine ameliorates diabetes type 2-induced nephropathy in rats

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Asian Pacific Journal of Tropical Biomedicine 2024年第1期14卷 8-16页

作者： Fatemah O.Kamel Ohoud Shagroud Mai AAlim A.Sattar Ahmad Gamal S Abd el-Aziz Abdulhadi S.Burzangi Duaa Bakhshwin Maha jamal Shahid Karim Department of Clinical Pharmacology Faculty of MedicineKing Abdulaziz UniversityJeddah 21589Saudi Arabia Department of Anatomy Faculty of MedicineKing Abdulaziz UniversityJeddah 21589Saudi Arabia

Objective:To assess the nephroprotective potential of agmatine in a rat model of streptozotocin-induced diabetic ***:A single dose of streptozotocin(40 mg/kg)coupled with a fructose diet induced diabetes in Wistar ***(40 and 80 mg/kg)was administered to rats for 12 *** body weight and fasting blood glucose were measured *** level,urine output,total protein,albumin,blood urea nitrogen,creatinine,and cystatin-C were also determined at the end of the ***,superoxide dismutase,glutathione,interleukin-1β,interleukin-6,and tumor necrosis factor-alpha were evaluated in kidney *** study was also performed using hematoxylin and eosin ***:Agmatine at both doses significantly increased final body weight,and lowered fasting blood glucose,urine output,insulin,total protein,albumin,blood urea nitrogen,creatinine,and cystatin-C levels compared with the diabetic group(Peliorated by agmatine ***:Agmatine alleviates diabetic nephropathy by improving renal functions and reducing inflammation and oxidative *** molecular mechanisms of its nephroprotective actions need to be investigated in future study.

关键词： Agmatine Type 2 diabetes Nephropathy Oxidative stress Nephroprotection

Optimization of energy exchange in microgrid networks: a coalition formation approach

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Protection and Control of Modern Power Systems 2019年第1期4卷 322-331页

作者： Chaimaa Essayeh Mohammed Raiss el fenni Hamza Dahmouni Department of Communication Systems INPTRabatMadinat Al IrfaneMorocco

In this paper, we elaborate a new strategy based on cooperative game theory models to encourage and manage the interactions in a MicroGrid network. The proposed strategy optimizes the cooperation and the energy exchange in a distributed μGrid network. The strategy consists of a two stage algorithm: Coalition formation algorithm which was specifically created to approximate the optimal set of coalitions that return considerable savings. And the Matching game to manage the energy exchange inside each coalition. The performance of our strategy was verified through simulations. These latter show that the losses can be considerably decreased by the use of the proposed strategy: the rate of the loss reduction can reach up to 20% if the two stages are applied on the network. Moreover, the strategy proved to have a fast convergence which makes it operational for real implemented networks.

关键词： MicroGrid network Energy optimization Cooperative Game theory Matching game Coalition formation

Total versus quantum correlations in a two-mode Gaussian state

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Communications in Theoretical Physics 2021年第5期73卷 38-45页

作者： jamal EI Qars Department of Physics Faculty of Applied SciencesAit-MelloulIbn Zohr UniversityAgadirMorocco EPTHE Department of PhysicsFaculty of SciencesIbn Zohr UniversityAgadirMorocco LPHE-MS Department of PhysicsFaculty of SciencesMohammed V UniversityRabatMorocco

In Li and Luo(2007 ***.A 76032327),the inequality(1/2)T≥Q was identified as a fundamental postulate for a consistent theory of quantum versus classical correlations for arbitrary measures of total T and quantum Q correlations in bipartite quantum ***,Hayden et al(2006 ***.26595)have conjectured that,in some conditions within systems endowed with infinite-dimensional Hilbert spaces,quantum correlations may dominate not only half of total correlations but total correlations ***,in a two-mode Gaussian state,quantifying T and Q respectively by the quantum mutual information I~G and the entanglement of formation(EoF)ε_(F)^(G),we verify thatε_(F)^(G),is always less than(1/2)I_(R)^(G( when I~G andε_(F)^(G) are defined via the Rényi-2 *** via the von Neumann entropy,ε_(F,V)^(G),may even dominate I_(V)^(G) itself,which partly consolidates the Hayden conjecture,and partly,provides strong evidence hinting that the origin of this counterintuitive behavior should intrinsically be related to the von Neumann entropy by which the EoFε_(F,V)^(G),is defined,rather than related to the conceptual definition of the EoFε_(F).The obtained results show that—in the special case of mixed two-mode Gaussian states—quantum entanglement can be faithfully quantified by the Gaussian Rényi-2 EoFε_(F,R)^(G),.

关键词： entanglement von Neumann and Rényi-2 entropies quantum mutual information Gaussian states spontaneous emission laser

Adaptive neural network observer for proton-exchange membrane fuel cell system

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Clean Energy 2023年第5期7卷 1078-1090页

作者： Abdelaziz el Aoumari Hamid Ouadi jamal el-Bakkouri Fouad Giri ERERA National School of Arts and CraftsMohammed V UniversityRabatMorocco LESE Lab ENSEMHassan II UniversityCasablancaMorocco Normandie University UNICAENENSICAENLAC14000 CaenFrance

This paper develops an adaptive neural network(NN)observer for proton-exchange membrane fuel cells(PEMFCs).Indeed,information on the oxygen excess ratio(OER)value is crucial to ensure optimal management of the durability and reliability of the *** OER indicator is computed from the mass of oxygen and nitrogen inside the PEMFC ***,the measurement process of both these masses is difficult and *** solve this problem,the design of a PEMFC state observer is ***,the behaviour of the fuel cell system is highly non-linear and its modelling is *** to this constraint,a multilayer perceptron neural network(MLPNN)-based observer is proposed in this paper to estimate the oxygen and nitrogen *** notable advantage of the suggested MLPNN observer is that it does not require a database to train the ***,the weights of the NN are updated in real time using the output *** addition,the observer parameters,namely the learning rate and the damping factor,are online adapted using the optimization tools of extremum ***,the proposed observer stability analysis is performed using the Lyapunov *** observer performances are validated by simulation under MATLAB®/Simulink®.The supremacy of the proposed adaptive MLPNN observer is highlighted by comparison with a fixed-parameter MLPNN observer and a classical high-gain observer(HGO).The mean rela-tive error value of the excess oxygen rate is considered the performance index,which is equal to 1.01%for an adaptive MLPNN and 3.95%and 9.95%for a fixed MLPNN and HGO,***,a robustness test of the proposed observer with respect to measurement noise is performed.

关键词： fuel cell system(PEMFC) multilayer perceptron neural network(MLPNN)observer optimization extremum seeking(ES) oxygen excess ratio(OER)

electronic and Optical Properties of TiS2 Determined from Generalized Gradient Approximation Study

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Chinese Physics Letters 2015年第9期32卷 96-99页

作者： Hamza el-Kouch Larbi el Farh jamal Sayah Allal Challioui Laboratoire de mecanique & energetique Departement de Physique Faculte des Sciences Universite Mohmnmed Premier Oujda Maroc Laboratoire de chimie organique macromol~culaire et produits naturels Equipe: Photochimie et Chimie Macromoleculaire Faculte des Sciences Universite Mohammed Premier Oujda. Maroc

The electronic and optical properties of TiS2 are studied of density functional theory. A linearized and augmented by using an ab-initio calculation within the frame plane wave basis set with the generalized gradient approximation as proposed by Perdew et al. is used for the energy exchange-correlation determination. The results show a metallic character of TiS2, and the plots of total and partial densities of states of TiS2 show the metallic character of the bonds and a strong hybridization between the states d of Ti and p of S below the Fermi energy. The optical properties of the material such as real and imaginary parts of dielectric constant （ε（w） = ε1（w）＋ iε2（w））, refractive index n（w）, optical reflectivity R（w）, for E / /x and E / /z are performed for the energy range of 0-.14 eV.

关键词： Ti ab electronic and Optical Properties of TiS2 Determined from Generalized Gradient Approximation Study

Advances in telemedicine for the management of the elderly cardiac patient

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Journal of Geriatric Cardiology 2021年第9期18卷 759-767页

作者： Nadim el jamal Bernard Abi-Saleh Hussain Isma’eel Division of Cariology American University of Beirut Faculty of Medicine and Medical CenterBeirutLebanon

Telemedicine is the use of information and communication technology to deliver healthcare at a *** has been resorted to during the COVID-19 pandemic to lessen the need for in-person patient care decreasing the risk of transmission,and it can be of benefit afterward in the management of cardiac *** elderly population has unique challenges concerning the use of telehealth *** thus review the advances in telemedicine technologies in treating elderly cardiac patients including in our discussion only studies with a mean age of participants above *** monitoring of blood pressure,weight,and symptoms,along with home ECG recording has been found to be superior to usual in-clinic follow *** remote monitoring with video conferencing with physicians,patient education websites,and applications is also of *** monitoring of Implantable Cardioverter Defibrillators(ICD)and Cardiac Resynchronization Therapy Defibrillators(CRT-D)is also beneficial but can be at the cost of an increase in both appropriate and inappropriate *** sensing devices compatible with remote monitoring have been developed and have been shown to improve care and *** smartphone software can detect arrhythmias using home ECG recordings and can detect atrial fibrillation using smartphone *** monitoring of implanted pacemakers has shown non-inferiority to in clinic follow *** the other hand,small-scale questionnaire-based studies demonstrated the willingness of the elderly cardiac patients to use such technologies,and their satisfaction with their use and ease of ***-scale studies should further investigate useability in samples more representative of the general elderly population with more diverse socioeconomic and educational ***,it seems that studying integrating multiple technologies into telehealth programs is of great *** efforts should also be put in validating the te

关键词： ECG CRT ICD Advances in telemedicine for the management of the elderly cardiac patient

Filtered High Gain Observer for an electric Vehicle’s electro-hydraulic Brake: Design and Optimization Using Multivariable Newton-based Extremum Seeking

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Chinese Journal of electrical Engineering 2023年第4期9卷 73-87页

作者： jamal el-bakkouri Hamid Ouadi Fouad Giri Mohamed Khafallah ENSEM Hassan II University of CasablancaCasablanca BP 8118Morocco ENSAM Rabat Mohammed V UniversityRabat BP 6207Morocco Department of electrical Engineering University of Caen NormandyCaen 14032France

Designing high-gain observers(HGOs)for the state estimation of an electric vehicle’s electrohydraulic brake(EHB)system is *** type of observer is applicable to model nonlinearities and constant feature ***,they are very sensitive to measurement noise,which is unavoidable in *** first novelty of this study is that it compensates for the measurement noise using a filtered high-gain observer(FHGO)to ensure EHB state *** proposed FHGO provides an estimate of the master cylinder pressure,motor current,and rotor speed from measurements of the rotor *** second novelty is the design of an extremum-seeking(ES)optimization loop to adjust the FHGO gains *** performance of the developed FHGO with ES-based online gain optimization was highlighted in the presence of model uncertainties and output measurement noise using a Matlab/Simulink *** superiority of the FHGO(even with a fixed gain)over a standard high gain observer(SHGO)was also demonstrated.

关键词： electrohydraulic brake filtered HGO measurement noise optimization extremum-seeking Lyapunov theory

Effect of rare earth on physical properties of Na_(0.5)Bi_(0.5)TiO_(3)system:A density functional theory investigation

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Journal of Rare Earths 2022年第3期40卷 473-481,I0005页

作者： Manal Benyoussef Halima Zaari jamal Belhadi Youssef el Amraoui Hamid Ez-Zahraouy Abdelilah Lahmar Mimoun el Marssi Laboratory of Physics of Condensed Matter(LPMC) University of Picardie Jules VerneScientific Pole80039Amiens Cedex 1France Laboratory of Condensed Matter and Indisciplinary Science(LaMCScI) Faculty of ScienceMohammed V UniversityBP 1014RabatMorocco National School of Arts and Crafts Moulay Ismail University50500MeknesMorocco

Na_(0.5)(Bi_(3/4)RE_(1/4))_(0.5)TiO_(3)(RENBT,RE=Nd,Gd,Dy,and Ho)compounds were investigated in the framework of first-principles calculations using the full potential linearized augmented plane wave(FP-LAPW)method based on the spin-polarized density functional theory implemented in the WIEN2k *** charge density distribution and Ti K-edge X-ray absorption spectra reveal that the RENBT compositions with high polarization values are accompanied by a higher TiO_(6)distortion,DyNBT,and NdNBT *** effect of the rare-earth elements on the polarization is confirmed experimentally with the collection of the hysteresis *** investigation of the electronic properties of the compounds highlights the emergence of a magnetization owing to the 4f orbital effect of the rare-earth ***,the investigation of the chemical ordering shows a short-range chemical ordering for the pure composition and an increased A-site disorder for dysprosium doped NBT *** increased disorder may speak for increased relaxor properties in the RE doped compositions.

关键词： Density functional theory Sodium bismuth titanate Rare earths A-site ordering Ferroelectric properties Magnetization

Comparative study of semiconductor power losses between CSI-based STATCOM and VSI-based STATCOM,both used for unbalance compensation

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Protection and Control of Modern Power Systems 2020年第1期5卷 56-69页

作者： Anas Benslimane jamal Bouchnaif Mohammed Essoufi Bekkay Hajji Loukmane el Idrissi Laboratory Renewable energy embedded system and information processingNational School of Applied SciencesUniversity of Mohammed IOujdaMorocco Laboratory of electrical Engineering and Maintenance Higher School of TechnologyUniversity of Mohammed IOujdaMorocco

In this paper,we present a detailed procedure to determine the semiconductor losses for both structures of a shunt STATCOM(Static Compensator),STATCOM based on Current Source Inverter(CSI)and STATCOM based on Voltage Source Inverter(VSI),both used for voltage unbalance *** a first step,we study the VSI-based STATCOM and the CSI-based STATCOM used in high speed railway *** we analyze the design and the sizing of the unbalance compensator in order to obtain an unbalance factor that does not exceed the limits imposed by the standards or by the energy *** that,we compare the performances obtained with both structures VSI-STATCOM and CSI-STATCOM,after calculating the semiconductor power losses in the STATCOM ***,we validate our approach by simulation over real data of unbalance compensation caused by the new high-speed railway in *** use the tools MATLAB/Simulink/Simpowersys for performing our simulations.

关键词： Power losses VSI CSI STATCOM Unbalance compensation Railway