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International Journal of Clinical Medicine 2014年第15期5卷 902-909页

作者： Mohammad Shameem Mazhar Alam Shagufta Moin Rakesh Bhargava Zuber Ahmad jamal akhtar Department of Biochemistry Jawaharlal Nehru Medical College Aligarh Muslim University Aligarh India Department of Tuberculosis and Respiratory Diseases Jawaharlal Nehru Medical College Aligarh Muslim University Aligarh UP 202002 India

Pulmonary Tuberculosis (PTB) and Community-Acquired Pneumonia (CAP) are common causes of consolidation patch in chest radiograph. Sputum Z-N staining is positive in 30% to 60% cases only and sputum examination has poor yield in CAP. This study aimed to assess the value of serum Procalcitonin (PCT) levels in patients with Pulmonary Tuberculosis (PTB) and Community-Acquired Pneumonia (CAP). Patients with new opacity in chest radiograph were included in the study. Serum sample were taken at admission and stored. Patient’s diagnosis were confirmed and categorized into pulmonary TB group (32) and community-acquired pneumonia group (23). Their mean PCT level was compared with mean PCT level of 25 controls. Serum procalcitonin levels were found to be significantly elevated in patients of community-acquired pneumonia as compared to patients of pulmonary tuberculosis. In presence of consolidation in x-ray chest, increased level of serum procalcitonin might be used to differentiate pulmonary tuberculosis from community-acquired pneumonia. High level of serum procalcitonin was associated with high mortality rate in community-acquired pneumonia patients.

关键词： Procalcitonin Tuberculosis Community-Acquired Pneumonia

Remote condition monitoring of rail tracks using distributed acoustic sensing(DAS):A deep CNN-LSTM-SW based model

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Green Energy and Intelligent Transportation 2024年第5期3卷 70-85页

作者： Md Arifur Rahman Suhaima jamal Hossein Taheri The Laboratory for Advanced Non-Destructive Testing In-situ Monitoringand Evaluation(LANDTIE)Department of Manufacturing EngineeringGeorgia Southern UniversityStatesboro 30458GAUSA Information Technology Department Georgia Southern UniversityStatesboro 30458GAUSA

Railroad condition monitoring is paramount due to frequent passage through densely populated *** significance arises from the potential consequences of accidents such as train derailments,hazardous materials leaks,or collisions which may have far-reaching impacts on communities and the surrounding *** a solution to this issue,the use of distributed acoustic sensing(DAS)-fiber optic cables along railroads provides a feasible tool for monitoring the health of these extended ***,analyzing DAS data to assess railroad health or detect potential damage is a challenging *** to the large amount of data generated by DAS,as well as the unstructured patterns and substantial noise present,traditional analysis methods are ineffective in interpreting this *** paper introduces a novel approach that harnesses the power of deep learning through a combination of CNNs and LSTMs,augmented by sliding window techniques(CNN-LSTM-SW),to advance the state-of-the-art in the railroad condition monitoring *** well as it presents the potential for DAS and fiber optic sensing technologies to revolutionize the proposed CNN-LSTM-SW model to detect conditions along the rail track *** insights from the data of High tonnage load(HTL)-a 4.16 km fiber optic and DAS setup,we were able to distinguish train position,normal condition,and abnormal conditions along the ***,our investigation demonstrated that the proposed approaches could serve as efficient techniques for processing DAS signals and detecting the condition of railroad infrastructures at any remote distance with DAS-Fiber optic cable ***,in terms of pinpointing the train's position,the CNN-LSTM architecture showcased an impressive 97%detection *** a sliding window,the CNN-LSTM labeled data,the remaining 3%of misclassified labels have been improved dramatically by predicting the exact locations of each type of ***,these prop

关键词： Distributed acoustic sensing(DAS)-Fiber optic cable Railroad condition monitoring and anomaly detection High tonnage load(HTL) Convolutional neural network-long short-term memory-sliding window(CNN-LSTM-SW)

Use of GIS and BIM for the integration of tunnel designand construction process in conventional tunneling

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Underground Space 2024年第3期16卷 261-278页

作者： Mansour Hedayatzadeh jamal Rostami Vasilis Sarhosis Mojtaba Nematollahi Nabiollah Hajiantilaki Abouzar Shafiepour University of Leeds Leeds LS29JTUK Colorado School of Mines GoldenCO 80401USA University of Minho Guimaraes 4800-058Portugal General Mechanic Company Tehran ***Iran Ettehadrah Consulting Engineers Tehran Q83GVWVIran

This paper presents the development of a framework for the parametric design of tunnels using geographic information system (GIS)mapping and building information modelling (BIM). According to the framework, a parametric representation of each system component (e.g., layers of rock mass, size of excavation, topography, fault geometry, primary lining, secondary lining, rock bolts, etc.) can beincorporated in the GIS model with high levels of detail and used for the automatic generation of numerical models for the design oftunnel construction. This parametric evaluation allows the designer to consider several levels of detail for each component, for the effi-cient design and process optimization in conventional tunneling. Information between parametric analysis and numerical simulations canbe freely exchanged with significantly reduced computational effort while results can be exported into BIM. It is anticipated that the proposed framework could lead to a comprehensive, yet efficient analysis of complex conventional tunneling project using parametric evaluations at the early design stages.

关键词： Geographic information system Building information modelling Conventional tunneling Numerical simulations Parametric analysis

A comparative in vitro study on the effect of SGLT2 inhibitors on chemosensitivity to doxorubicin in MCF-7 breast cancer cells

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Oncology Research 2024年第5期32卷 817-830页

作者： SHAHID KARIM ALANOUD NAHER ALGHANMI MAHA jamal HUDA ALKREATHY ALAM jamal HIND A.ALKHATABI MOHAMMED BAZUHAIR AFTAB AHMAD Department of Clinical Pharmacology Faculty of MedicineKing Abdulaziz UniversityJeddahSaudi Arabia Department of Biochemistry Faculty of ScienceKing Abdulaziz UniversityJeddahSaudi Arabia Department of Biochemistry College of ScienceUniversity of JeddahJeddah21959Saudi Arabia Health Information Technology Department The Applied CollegeKing Abdulaziz UniversityJeddahSaudi Arabia Pharmacovigilance and Medication Safety Unit Center of Research Excellence for Drug Research and Pharmaceutical IndustriesKing Abdulaziz UniversityJeddahSaudi Arabia

Cancer frequently develops resistance to the majority of chemotherapy *** study aimed to examine the synergistic cytotoxic and antitumor effects of SGLT2 inhibitors,specifically Canagliflozin(CAN),Dapagliflozin(DAP),Empagliflozin(EMP),and Doxorubicin(DOX),using in vitro *** precise combination of CAN+DOX has been found to greatly enhance the cytotoxic effects of doxorubicin(DOX)in MCF-7 ***,it was shown that cancer cells exhibit an increased demand for glucose and ATP in order to support their ***,when these medications were combined with DOX,there was a considerable inhibition of glucose consumption,as well as reductions in intracellular ATP and lactate ***,this effect was found to be dependent on the dosages of the *** addition to effectively inhibiting the cell cycle,the combination of CAN+DOX induces substantial modifications in both cell cycle and apoptotic gene *** work represents the initial report on the beneficial impact of SGLT2 inhibitor medications,namely CAN,DAP,and EMP,on the responsiveness to the anticancer properties of *** underlying molecular mechanisms potentially involve the suppression of the function of SGLT2.

关键词： SGLT2 Cancer Cytotoxicity ATP Cell cycle

Synergistic enhancement of photocatalytic and antimicrobial efficacy of nitrogen and erbium co-doped ZnO nanoparticles

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Journal of Rare Earths 2024年第5期42卷 859-868,I0002页

作者： Sudipta Mondal Moniruzzaman jamal Sikder Ashikuzzaman Ayon Md Jannatul Ferdous Anik Md Muktadir Billah Department of Materials and Metallurgical Engineering Bangladesh University of Engineering and TechnologyDhaka1000Bangladesh School of Materials Engineering Purdue UniversityWest LafayetteIN47907USA Department of Materials Science and Engineering University of CaliforniaBerkeleyCA94720USA Department of Materials Science and Engineering Northwestern UniversityEvanstonI28USA

Using the chemical co-precipitation approach,a series of nitrogen(N) and erbium(Er) co-doped ZnO nanoparticles(NPs) was effectively synthesized to enhance the photocatalytic and antibacterial *** characterization techniques,including X-ray diffraction(XRD),X-ray photoelectron spectro scopy(XPS),scanning electron microscopy(SEM),UV-vis,and photoluminescence(PL) spectroscopy,were carried out to validate the evaluated photocatalytic and antibacterial *** analysis confirms the pure wurtzite ZnO phase without the presence of any secondary *** analysis confirms the succe ssful incorporation of nitrogen and erbium into the ZnO *** optical bandgap of ZnO calculated from UV-vis spectroscopy shows a redshift after Er-N co-doping,with the lowest bandgap of 3.215 eV calculated for Zn_(0.97)Er_(0.03)N_(0.01)O_(0.99) *** images demonstrate the formation of nanorods after N-Er co-doping,followed by gradually increase d rod diameter and length after N-Er ***,the photocatalytic activities of ZnO samples we re measured by their ability to facilitate the photodegradation of Rhodamine B under UV *** with 1 mol% N doping exhibits 88% photodegradation of RhB under UV light within 360 min,and the photodegradation and antibacterial activity are greatly improved with Er *** fact,3 mol% Er-1 mol% N doped ZnO NPs demonstrate the highest photocatalytic activity,with approximately 96% degradation after 360 min,as well as superior antibacterial activity against Staphylococcus aureus(Gram-positive bacteria) and Pseudomonas aeruginosa(Gram-negative bacteria) with the highest zone of inhibition(ZOI) of 16 nm,due to nanorod formation,increased reactive oxygen species(ROS),and decreased electron-hole recombination,as validated by SEM,XPS,and PL spectroscopy.

关键词： Chemical co-precipitation Co-doping Bandgap Photocatalysis Rare earths Antimicrobial

Platform Evolution in an Oligo-Miocene Back-arc Basin:An Example from the Central Iran Basin

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Acta Geologica Sinica(English Edition) 2024年第1期98卷 185-206页

作者： Masoud SHARIFI-YAZDI Amirhossein ENAYATI jamal SALEHI AGHDAM Mohammad BAHREHVAR Seyed Mustafa REZAEI Department of Geology Faculty of Earth SciencesGeography and AstronomyUniversity of Vienna1090 Vienna.Austria Geology and Geophysics Department Tehran Energy Consultants(TEC Co.)TehranIran School of Geology College of ScienceUniversity of TehranTehranIran Department of Geology Tarbiat Modares UniversityTehranIran

The Qom Formation is the most important hydrocarbon reservoir target in Central *** Qom platform developed in a back-arc basin during the Oligo-Miocene due to the closing of the Tethyan *** formation consists of a variety of carbonate and non-carbonate facies deposited on a platform ranging from supratidal to basin.A combination of tectonic and eustatic events led to some lateral and vertical facies variations in the study *** third-order depositional sequences and related surfaces were identified regarding vertical facies changes in the studied sections of this Oligo-Miocene *** to all results and data,this succession was initially deposited during the Chattian upon a distally steepened ramp of siliciclastic-carbonate composition,including the Bouma ***,from the late Chattian to the Aquitanian,the platform changed into a homoclinal carbonate ramp with a gentle *** respect to tectonic activity,this phase was a calm period during the deposition of the Qom ***,a drowned carbonate platform and a rimmed shelf emerged during the Burdigalian,terminated by the continental deposits of the Upper Red *** all geological characteristics,three main tectono-eustatic evolutionary phases have been recognized in the Qom back-arcbasin.

关键词： carbonate ramp depositional facies submarine fan eustasy basement faults back-arc basin

Correlation of periodontal inflamed surface area with glycated hemoglobin,interleukin-6 and lipoprotein(a)in type 2 diabetes with retinopathy

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World Journal of Diabetes 2024年第4期15卷 686-696页

作者： Nusreen jamal Thazhe Poyil Rosamma Joseph Vadakkekuttical Chandni Radhakrishnan Department of Periodontics Government Dental College(Affiliated to Kerala University of Health Sciences)Calicut 673008KeralaIndia Department of Medicine Government Medical College(Affiliated to Kerala University of Health Sciences)Calicut 673008KeralaIndia

BACKGROUND The two-way relationship between periodontitis and type 2 diabetes mellitus(T2DM)is well *** hyperglycemia contributes to increased periodontal destruction and severe periodontitis,accentuating diabetic *** inflammatory link exists between diabetic retinopathy(DR)and periodontitis,but the studies regarding this association and the role of lipoprotein(a)[Lp(a)]and interleukin-6(IL-6)in these conditions are scarce in the *** To determine the correlation of periodontal inflamed surface area(PISA)with glycated Hb(HbA1c),serum IL-6 and Lp(a)in T2DM subjects with *** This cross-sectional study comprised 40 T2DM subjects with DR and 40 T2DM subjects without *** subjects were assessed for periodontal parameters[bleeding on probing(BOP),probing pocket depth,clinical attachment loss(CAL),oral hygiene index-simplified,plaque index(PI)and PISA],and systemic parameters[HbA1c,fasting plasma glucose and postprandial plasma glucose,fasting lipid profile,serum IL-6 and serum Lp(a)].RESULTS The proportion of periodontitis in T2DM with and without DR was 47.5%and 27.5%*** of periodontitis,CAL,PISA,IL-6 and Lp(a)were higher in T2DM with DR group compared to T2DM without DR *** difference was observed in the mean percentage of sites with BOP between T2DM with DR(69%)and T2DM without DR(41%),but there was no significant difference in PI(P>0.05).HbA1c was positively correlated with CAL(r=0.351,P=0.001),and PISA(r=0.393,P≤0.001)in study subjects.A positive correlation was found between PISA and IL-6(r=0.651,P<0.0001);PISA and Lp(a)(r=0.59,P<0.001);CAL and IL-6(r=0.527,P<0.0001)and CAL and Lp(a)(r=0.631,P<0.001)among study *** Despite both groups having poor glycemic control and comparable plaque scores,the periodontal parameters were higher in DR as compared to T2DM without *** a bidirectional link exists between periodontitis and DM,the presence of DR may have contr

关键词： Type 2 diabetes mellitus Periodontitis Periodontal inflamed surface Area Glycated Hb Diabetic retinopathy

Disease clearance in ulcerative colitis:A new therapeutic target for the future

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World Journal of Gastroenterology 2024年第13期30卷 1801-1809页

作者： Syed Adeel Hassan Neeraj Kapur Fahad Sheikh Anam Fahad Somia jamal Division of Digestive Disease and Nutrition University of KentuckyLexingtonKY 40536United States Department of Pathology and Laboratory Medicine Montefiore Medical CenterAlbert Einstein College of MedicineNew YorkNY 10461United States Division of Primary Care Essen HealthcareNew YorkNY 10457United States Department of Internal Medicine Karachi Medical and Dental CollegeKarachi 74700SindhPakistan

Advancements in murine modeling systems for ulcerative colitis have diversified our understanding of the pathophysiological factors involved in disease onset and *** has fueled the identification of molecular targets,resulting in a rapidly expanding therapeutic ***,management strategies have evolved from symptomatic resolution to well-defined objective endpoints,including clinical remission,endoscopic remission and mucosal *** the incorporation of these assessment modalities has permitted targeted intervention in the context of a natural disease history and the prevention of complications,studies have consistently depicted discrepancies associated with ascertaining disease status through clinical and endoscopic *** recommendations lack consideration of histological *** simultaneous achievement of clinical,endoscopic,and histologic remission has not been fully *** has laid the groundwork for a novel therapeutic outcome termed disease clearance(DC).This article summarizes the concept of DC and its current evidence.

关键词： Inflammatory bowel disease Ulcerative colitis Clinical remission Endoscopic remission Histological remission Mucosal healing Disease clearance

Classifying Modulations in Communication Intelligence Using Deep Learning Networks

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Journal of Systems Science and Information 2024年第3期12卷 379-392页

作者： Yahya BENREMDANE Said jamal Oumaima TAHERI Jawad LAKZIZ Said OUASKIT Department of Physics Faculty of Science Ben M'sikUniversity HassanⅡCasablanca 20100Morocco

The present research employs artificial intelligence to come up with an automatic solution for the modulation's classification of various radio signal *** a result,the work we performed involved selecting the database required for supervised deep learning,evaluating the performance of current techniques on unprocessed communication signals,and suggesting a deep learning networkbased method that would enable the classification of modulation types with the best possible ratio between computation time and *** started by examining the automatic classification models that are currently in *** light of the difficulty of forecasting in low Signal Noise Ratio(SNR)situations,we suggested an ensemble learning strategy based on adjusted Res Net and Transformer Neural Network,which is effective at extracting multi-scale features from the raw I/Q sequence ***,we produced an architecture that is simple to use and apply to communication *** architecture of this solution is strong and optimal,enabling it to determine the type of modulation with up to 95%accuracy automatically.

关键词： automatic modulation classification artificial intelligence deep learning radio frequency electronicwarfare

The Lambert-G Family:Properties,Inference,and Applications

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Computer Modeling in Engineering & Sciences 2024年第7期140卷 513-536页

作者： jamal N.Al Abbasi Ahmed Z.Afify Badr Alnssyan Mustafa S.Shama Accounting Department Ashur UniversityBaghdad10011Iraq Department of Statistics Mathematics and InsuranceBenha UniversityBenha13511Egypt Department of Management Information Systems and Production Management College of Business and EconomicsQassim UniversityBuraydah51452Saudi Arabia Department of Basic Sciences Common First Year(CFY)King Saud UniversityRiyadh11362Saudi Arabia Department of Mathematics and Statistics Osim Higher Institute of Administrative ScienceOsim12961Egypt

This study proposes a new flexible family of distributions called the Lambert-G *** Lambert family is very flexible and exhibits desirable *** three-parameter special sub-models provide all significantmonotonic and non-monotonic failure rates.A special sub-model of the Lambert family called the Lambert-Lomax(LL)distribution is *** expressions for the LL statistical properties are *** of the LL distribution are addressed mathematically based on its hazard *** estimation of the LL parameters is discussed using six estimation *** performance of this estimation method is explored through simulation *** usefulness and flexibility of the LL distribution are demonstrated empirically using two real-life data *** LL model better fits the exponentiated Lomax,inverse power Lomax,Lomax-Rayleigh,power Lomax,and Lomax distributions.

关键词： Lambert function Lomax distribution maximum likelihood hazard function statistical model simulation