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Effectivity of Thromboprophylxie in Dakar’s medical Areas

Open Journal of Internal medicine 2020年第1期10卷 35-43页

作者： B. Djiba m. Dieng C. m. A. Halim m. sow B. s. Kane m. A. Ndour B. C. Fall N. Diagne A. C. Ndao A. Faye s. Ndongo A. Pouye Department of Internal medicine Aristide Le Dantec Hospital Dakar-Étoile Senegal Department of Internal medicine Dalal Jam Hospital Dakar Senegal

Introduction: Venous thromboembolic disease (VTE) is a real public health problem worldwide. The practice guide produced periodically by the American College of Chest Physicians (ACCP) has become the international standard. However, thromboprophylaxis remains underused. methodology: We carried out a descriptive cross-sectional study. The goals of that study were to evaluate the effectiveness of the practice of thromboprophylaxis in the various medical services of the Dakar Public Hospitals. Our investigation was conducted for two weeks in september 2017. Results: 160 patients were included (81 men and 79 women) in our series, with male predominance: sex ratio of 1.02. The average age was 48. Infectious pathologies were the predominant clinical pictures (35% of cases). The thromboembolic risk factors (RF) mainly found were represented by prolonged bed rest, followed by cardiovascular (RF): age greater than 60 years (31.2%), hypertension (8.8%), obesity (4.4%) and diabetes (3.8%). The thromboembolic RF of patients hospitalized in these medical services has been evaluated empirically. We noted a lack of use of the VTE risk assessment scores. 40.9% (n = 56) of patients received overall VTE prophylaxis, a rate corresponding to almost half of those at risk (51.4%). This result reflects an under-use of thromboprophylaxis in the Dakar medical environment and a low level of adherence by practicians to the guidelines on VTE prophylaxis. Conclusion: It is therefore recommended to develop a national strategy to assess patients at risk for VTE, as well as measures to educate and inform doctors about the appropriate forms of thromboprophylaxis.

关键词： Thromboprophylaxis Anticoagulant Thromboembolic Disease

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Immunosuppressive Treatment of Connective Tissue Disease and Occurrence of Tuberculosis

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Open Journal of Rheumatology and Autoimmune Diseases 2020年第2期10卷 57-63页

作者： m. Dieng B. Djiba B. s. Kane B. C. Fall m. A. Ndour m. sow N. Diagne A. C. Ndao A. Faye s. Ndongo A. Pouye service de médecine Interne hôpital Aristide Le Dantec Dakar-étoile Sénégal service de médecine interne hôpital Dalal Jam Dakar Sénégal

Introduction: The occurrence of tuberculosis (TB) during the follow-up of Connective tissue diseases (CTD) is a particular situation often posing real diagnostic problems. This is an association described in the literature. Patients and methods: We conducted a retrospective and descriptive study at the internal medicine department of Aristide Le Dantec Hospital. The purpose of this study was to determine the treatment that patients followed for CTD and suffering from TB took before the occurrence of this one. Results: During a study period of 11 years and 6 months, 21 cases of TB were diagnosed in 602 cases of CTD (0.03%). The predominance was female with a sex ratio (H/F) of 0.6. The median age was 42 years old. The majority of cases originated from the Dakar region (13 patients or 61.9%) and 85.7% had previous follow-up exclusively in modern medicine and 21 cases (95%) received the CTD’s treatment. This consisted of prednisone (90.5%) combined with methotrexate (52.4%), azathioprine (23.8%) or cyclophosphamide (19.4%). The respective medians doses of these drugs were 12.5 mg per day for prednisone, 13.5 mg per week for methotrexate and 100 mg per day for azathioprine. The median duration of patient follow-up was 36 months. The cumulative dose of prednisone during this period was 23.6 g and that of methotrexate 2.25 g. CTD were dominated by rheumatoid arthritis (RA) (57.1%), and systemic lupus (19%). Isolated cases of systemic scleroderma, primary sjôgren, sHARP syndrom, mixed connective tissue disease, and multiple autoimmune syndrom were noted. TB was localized in 95% of cases, readily bilateral and poorly disseminated. The respective medians diagnostic delays for systemic disease and TB were 21 months and 5 months. Tuberculin intradermal reaction was performed in 16 cases and was positive in 9 cases, sputum bacilli was performed in 19 cases and was positive in 15 cases. Conclusion: The association of TB and CTD was characterized by its rarity, its poorly di

关键词： Tuberculosis Connective Tissue Disease Corticosteroid Immunosuppressive Therapy

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XIAO mI BAND REVIEWED

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城市漫步（全国英文版） 2015年第8期 29-29页

作者： jam mcGuinness 不详

I'm a real sucker for the simple and sleek look.I always find myself shopping in mUJIf for example,and when it comes to tech,Apple is my one-stop ***,both of these brands come with a hefty price tag-and this is where ... 详细信息

关键词： shopping comes beauty

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Tunnel effects on ring road traffic flow based on an urgent-gentle class traffic model

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Theoretical & Applied mechanics Letters 2021年第4期11卷 230-235页

作者： Yongliang Zhang m.N.smirnova Jian ma N.N.smirnov Zuojin Zhu Faculty of Engineering science University of Science and Technology of ChinaHefei 230026China Faculty of mechanics and mathematics Lomonosov Moscow State UniversityMoscow 119992Russian Federation moscow Center for Fundamental and Applied mathematics Moscow 119992Russian Federation scientific Research Institute for system Analysis Russian Academy of SciencesMoscow 119992Russian Federation Naval Architecture and Civil Engineering Jiangsu University of Science and TechnologyZhenjiang 215600China

To explore tunnel effects on ring road traffic flow,a macroscopic urgent-gentle class traffic model is put *** model identifies vehicles with urgent and gentle classes,chooses the tunnel speed limit as free flow speed to express the fundamental diagram in the tunnel,and adopts algebraic expressions to describe traffic pressure and sound *** two speed trajectories at the Kobotoke tunnel in Japan,the model is validated,with good agreement with observed *** results indicate that in the case of having no ramp effects,tunnel mean travel time is almost constant dependent on tunnel *** initial density normalized by jam density is above a threshold of about 0.21,a traffic shock wave originates at the tunnel entrance and propagates *** a threshold drops slightly as a result of on-ramp merging effect,the mean travel time drops as off-ramp diversion effect intensifies *** findings deepen the understanding of tunnel effects on traffic flow in reality.

关键词： Tunnel effects Travel time Density threshold Ramp effects

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7α-O-IA-DPN:特异性碘标记阿片配体的研制和评价

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北京医科大学学报 1998年第3期30卷 210-212页

作者：王荣福魏锦泉北京医科大学第一医院核医学科福建省漳州市医院同位素科

目的：研制和评价新碘标阿片受体显像剂７αＯｉｏｄｏａｌｙｌｄｉｐｒｅｎｏｒｐｈｉｎｅ（７αＯＩＡＤＰＮ）。方法：选用阿片肽拮抗剂ＤＰＮ经碘代锡烷标记法成功地获得了一个原始的碘标阿片肽类似物，并对其进行理化... 详细信息

目的：研制和评价新碘标阿片受体显像剂７αＯｉｏｄｏａｌｙｌｄｉｐｒｅｎｏｒｐｈｉｎｅ（７αＯＩＡＤＰＮ）。方法：选用阿片肽拮抗剂ＤＰＮ经碘代锡烷标记法成功地获得了一个原始的碘标阿片肽类似物，并对其进行理化性能、药理作用和生物学功能评价。结果：体外和体内阿片受体结合分析表明这一新的阿片配体具有非常高的亲和力（Ｋｉ＝４×１０－４μｍｏｌ／Ｌ）。注药后２０ｍｉｎ动物脑内的特异性结合占６３％，且其在脑内滞留时间较长而有利于成像。阿片抑制试验和抗痛活性研究分别反映碘标７αＯＩＡＤＰＮ可能对３种阿片受体（μ，δ，κ）都有亲和力，并保持了原有的药理特性和生物学功能。结论：碘标７αＯＩＡＤＰＮ作为新阿片受体显像剂较适于今后ＳＰＥＣＴ阿片受体研究。

关键词：受体碘标记 IA-DPN 阿片受体

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Chemical, Nutritional and Organoleptical Characteristics of Orange-Based Formulated Low-Calorie jams

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Food and Nutrition sciences 2015年第13期6卷 1229-1244页

作者： Rafeek m. Abolila Hassan Barakat Hassan A. El-Tanahy Hamdy A. El-mansy Food Technology Department Faculty of Agriculture Benha University Banha Egypt

Twelve low-calorie orange-based formulated jams were prepared mainly from orange, pumpkin and papaya, and then sweetened using fructose (F), stevioside (st) and sucralose (su). The nutritional value of formulated jams was estimated after the approximate chemical composition and total soluble solid have been determined. The effect of storage on total phenolic compounds, antioxidant capacity, carotenoids content and vitamin C was investigated. Organoleptical attributes of prepared low-calorie jams were done as well. Results indicated that the nutritive value [kcal 100 g–1 fw] ranged from 88.10 ± 0.60 to 164.34 ± 0.41;total phenol content (TPC, mg GAE 100 g–1 fw] ranged from 188.52 ± 2.45 to 411.79 ± 3.3;the antioxidant capacity (μmol TE g–1 fw) ranged from 14.57 ± 0.86 to 32.39 ± 1.19;total carotenoids [mg 100 g–1 fw] ranged from 115.20 ± 5.66 to 204.33 ± 4.21;vitamin C [mg 100 g fw] ranged from 8.94 ± 1.07 to 28.77 ± 4.46;total soluble solids [Brix] ranged from 22.53 ± 0.05 to 43.37 ± 0.13. jams storage for a period of 12 months at room temperature led to a decrease in vitamin C content, TPC, antioxidant capacity, while total soluble solids (Tss) and carotenoids increased during storage. The results of organoleptical attributes showed that the formulas O11, O1 had the highest score of color and odor respectively while O7 recorded maximum score for taste, texture and bitterness respectively. statistical analysis showed that storage intervals and treatments had a significant (p sensory quality of diet jam. The organoleptical characteristics were affected with the extension of shelf-life. Addition of stevioside and sucralose to formulate the low-calorie jam increased total phenol and antioxidant capacity, improved color, taste and produced targeted low-calorie jams. The use of sweeteners such as fructose, sucralose and stevioside in the manufacture of orange diet jam was shown to be satisfactory, resulting in low-calorie jams, improved the quality and

关键词： Low-Calorie jam Chemical Nutritional Organoleptical Characteristics

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sensory Evaluation of syneresis Reduced jam and marmalade Containing Gum Arabic from Acacia senegalvar. kerensis

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Food and Nutrition sciences 2019年第11期10卷 1334-1343页

作者： Ruth I. Kavaya mary N. Omwamba Ben N. Chikamai symon m. mahungu Dairy Food Science and Technology Department Egerton University Nakuru Kenya Network for Natural Gums and Resins in Africa (NGARA) Nairobi Kenya

jams and marmalades are some of the most popular food products because of their low cost, all year long availability and appealing sensory properties. These products are described as gels with pectin as the gelling agent used in its formulation. Gels are a form of matter intermediate between a solid and a liquid. They consist of polymeric molecules cross-linked to form tangles, and interconnected molecular network immersed in a liquid medium. However, the jams and marmalades require stabilization by hydrocolloids. The most common hydrocolloid stabilizer is pectin which is available as a low methoxy pectin or high methoxy pectin. Unfortunately, under mechanical stress, pectin gels may be damaged leading to the release of colloidal water. The release of the colloidal water is termed as syneresis. This problem may be solved by integrating pectin with other stabilizers having thickening properties. jams were prepared using plums and pineapples while marmalades were prepared from oranges and lemons. Gum Arabic from Acacia senegal var. kerensis was added in the range of 1% - 5% which fell within the additives category. The prepared jams and marmalades underwent sensory evaluation using semi-trained panelists. The prepared jams and marmalades showed no evidence of syneresis. The jams and marmalades were subjected to a sensory panel who scored the different attributes against a 7-point hedonic scale. Gum Arabic at different levels was found to have a significant contribution to the consumer acceptance of the fruit spreads prepared. This is the first time that syneresis reduced jams and marmalades containing gum Arabic from Acacia senegal var. kerensis are being reported. sensory evaluation was carried out on different fruit spreads used in the study to assess the impact of gum Arabic from Acacia senegal var. Kerensis. The parameters include taste, texture, spreadability, aroma, flavour, colour and general acceptability. Red plum jam and Pineapple jam had its best performanc

关键词： Gum Arabic syneresis jam marmalade

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sensory Analysis of sugar Reduced jam Containing Gum Arabic from Acacia senegalvar. kerensis

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Food and Nutrition sciences 2019年第11期10卷 1277-1286页

作者： Eugenia W. Gakuru mary N. Omwamba Ben N. Chikamai symon m. mahungu Dairy and Food science and Technology Department Egerton University Nakuru Kenya Natural Gums and Resins in Africa (NGARA) Nairobi Kenya

Reducing sugar in jam has an effect on the physico-chemical as well as sensory properties of the jam. To compensate for some of the functional properties lost, other co-solutes may be used. Therefore the objective of this study was to use gum Arabic from Acacia senegal var. kerensis in formulation of a reduced sugar jam from plums and pineapple fruits. The innovatively prepared jam was subjected to sensory evaluation by a semi-trained panel. Twelve formulations were prepared in factorial arrangement in a completely randomized design. The products were rated using a seven-point hedonic scale for colour, taste, texture/spreadability, mouth feel and general acceptability. Data were analysed using sAs, 2004 (version 9.1.3) to perform analysis of variance and determine the least squares means for each variable. The main effect of the study was the level of gum Arabic at 15% and 20% w/w, level of sugar content at 30 and 35% w/w, and the type of fruit. A control product was prepared for the two sugar levels but without gum Arabic. significance was established at p senegal var. kerensis is being reported.

关键词： Gum Arabic sucrose/sugar Reduced sugar jam sensory Evaluation

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入口匝道衔接区域交通流运行机理解析

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同济大学学报（自然科学版） 2008年第12期36卷 1652-1655页

作者：杨晓芳付强张红军同济大学交通工程系上海200092 上海理工大学交通工程系上海200093

由于对交通流运行和演变机理解析不足,从而导致入口匝道管理和控制策略缺乏针对性和实际可操作性,采用波动理论方法建立数学模型,分析不同匝道和主线上游流量条件下,合流区、匝道合流区上游、合流区下游及匝道等处的交通流运行状态和交... 详细信息

由于对交通流运行和演变机理解析不足,从而导致入口匝道管理和控制策略缺乏针对性和实际可操作性,采用波动理论方法建立数学模型,分析不同匝道和主线上游流量条件下,合流区、匝道合流区上游、合流区下游及匝道等处的交通流运行状态和交通流的演变规律,解析入口匝道无控制时拥堵的形成和传播机理,从而为相关管理和控制策略的提出和优化提供理论支持.实例分析表明,衔接区域交通流运行规律与实际交通流运行符合较好.

关键词：入口匝道运行机理衔接区域波动理论

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甘蔗渣芦笋皮加入提高了甘薯淀粉发泡性能

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绿色包装 2019年第3期 74-74页

作者： jam Pier Cruz-Tirado Ricardo Vejarano Delia R. Tapia-Blácido Luis m. Angelats-silva Raúl siche 不详

利用甘蔗蔗渣(sB)和芦笋皮(AP)这两种农业工业废弃物,对以甘薯淀粉为基础的泡沫托盘(分别为淀粉/sB 和淀粉/AP托盘)进行了生物降解,提高了泡沫托盘的性能。制备了含不同浓度sB 和AP(0%-40%w/w)的淀粉/sB和淀粉/AP 托盘,并对其微观结构... 详细信息

利用甘蔗蔗渣(sB)和芦笋皮(AP)这两种农业工业废弃物,对以甘薯淀粉为基础的泡沫托盘(分别为淀粉/sB 和淀粉/AP托盘)进行了生物降解,提高了泡沫托盘的性能。制备了含不同浓度sB 和AP(0%-40%w/w)的淀粉/sB和淀粉/AP 托盘,并对其微观结构、物理、热学和力学性能进行了表征。纤维废料的加入使发泡托盘发黄,与无纤维的甘薯淀粉发泡托盘相比,发泡托盘亮度低,孔隙率高,机械阻力大,变形性好,吸水性好。添加sB的泡沫托板多孔性较低,吸水能力较低,抗拉强度较AP高。AP纤维的浓度越高(大于30%),泡沫托盘就越容易膨胀。纤维废弃物的加入提高了甘薯淀粉泡沫托盘的热稳定性。所制备的复合发泡托盘可作为膨化聚苯乙烯在食品干包装中的替代品。

关键词：甘薯淀粉发泡性能甘蔗渣芦笋皮工业废弃物纤维废弃物无纤维生物降解

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