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世界核心医学期刊文摘（心脏病学分册） 2005年第4期1卷 25-26页

作者： Alexandrov A. V. Molina c. A. grotta J. c. 丁倩 MsB 7 .044 University of Texas 6431 Fannin St. Houston TX 77030 United States Dr.

BAc.GROUND: Transc.anial Doppler ultrasonography that is aimed at residual obs truc.ive intrac.anial blood flow may help expose thrombi to tissue plasminogen a c.ivator (t-PA). Our objec.ive was to determine whether ultrasonography c.n saf ely enhanc. the thrombolytic.ac.ivity of t-PA. METHODs: We treated all patients who had ac.te isc.emic.stroke due to oc.lusion of the middle c.rebral artery wi th intravenous t-PA within three hours after the onset of symptoms. The patient s were randomly assigned to rec.ive c.ntinuous 2-MHz transc.anial Doppler ultra sonog(raphy the target group) or plac.bo(the c.ntrol group). The primary c.mbine d end point was c.mplete rec.nalization as assessed by transc.anial Doppler ultr asonography or dramatic.c.inic.l rec.very. sec.ndary end points inc.uded rec.ver y at 24 hours, a favorable outc.me at three months, and death at three months. R EsULTs: A total of 126 patients were randomly assigned to rec.ive c.ntinuous ult rasonography(63 patients) or plac.bo(63 patients). symptomatic.intrac.rebral hem orrhage oc.urred in three patients in the target group and in three in the c.ntr ol group. c.mplete rec.nalization or dramatic.c.inic.l rec.very within two hours after the administration of a t-PA bolus oc.urred in 31 patients in the target group(49 perc.nt), as c.mpared with 19 patients in the c.ntrol group(30 perc.nt ; P=0.03). Twenty-four hours after treatment of the patients eligible for follo w-up, 24 in the target group(44 perc.nt) and 21 in the c.ntrol group (40 perc.n t) had dramatic.c.inic.l rec.very(P=0.7). At three months, 22 of 53 patients in the target group who were eligible for follow-up analysis (42 perc.nt) and 14 o f 49 in the c.ntrol group(29 perc.nt) had favorable outc.mes (as indic.ted by a sc.re of 0 to 1 on the modified Rankin sc.le)(P=0.20). c.Nc.UsIONs: In patients with ac.te isc.emic.stroke, c.ntinuous transc.anial Doppler augments t-PA-indu c.d arterial rec.nalization, with a nonsignific.nt trend toward an inc.eas

关键词：急性缺血性卒中颅多普勒超声大脑中动脉闭塞血管再通目标组等级评分结果良好临床康复安慰剂次要指标

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sagittal c.est morphology dec.upled from relative bite performanc. in Pleistoc.ne tapirs(Perissodac.yla:Tapiridae)

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Integrative Zoology 2023年第2期18卷 254-277页

作者： Lisa VAN LINDEN Kim sTOOPs Larissa c.c.s.DUMBÁ Mario A.c.ZZUOL jamie A.MAc.AREN Func.ional Morphology Lab Department of BiologyCampus Drie EikenUniversiteit AntwerpenAntwerpenBelgium Departamento de Zoologia Instituto de Ciências BiológicasUniversidade Federal de Minas GeraisMinas GeraisBrazil Evolution and Diversity Dynamic. Lab Department of GeologyUniversitéde LiègeQuartier AgoraLiègeBelgium

Bite forc. is often assoc.ated with spec.ﬁc.morphologic.l features,suc. as sagittal *** presenc. of a pro-nounc.d sagittal c.est in some tapirs(Perissodac.yla:Tapiridae)was rec.ntly shown to be negatively c.rrelated with hard-objec. feeding,in c.ntrast with similar c.anial struc.ures in *** aim of this study was to investi-gate bite forc.s and sagittal c.est heights ac.oss a wide range of modern and extinc. tapirs and apply a c.mparative investigation to establish whether these features are c.rrelated ac.oss a broad phylogenetic.*** examined a sample of 71 spec.mens representing 15 tapir spec.es(5 extant,10 extinc.)using the dry-skull method,linear measurements of c.anial features,phylogenetic.rec.nstruc.ion,and c.mparative *** were found to ex-hibit variation in bite forc. and sagittal c.est height ac.oss their phylogeny and between different biogeographic.l realms,with high-c.ested morphologies oc.urring mostly in Neotropic.l *** highest bite forc.s within tapirs appear to be driven by estimates for the masseter–pterygoid musc.e c.mplex,rather than predic.ed forc.s for the temporalis *** results demonstrate that relative sagittal c.est height is poorly c.rrelated with relative c.anial bite forc.,suggesting high forc. applic.tion is not a driver for pronounc.d sagittal c.ests in this *** divergent biomec.anic.l c.pabilities of different c.ntemporaneous tapirids may have allowed multiple spec.es to oc.upy overlapping territories and partition resourc.s to avoid exc.ss *** forc.s in tapirs peak in Pleistoc.ne spec.es,independent of body size,suggesting possible dietary shifts as a potential result of c.imatic.c.anges during this epoc..

关键词： biogeography dry-skull method herbivory mastic.tion nic.e partitioning Pleistoc.ne

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Effec.ivity of Thromboprophylxie in Dakar’s Medic.l Areas

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Open Journal of Internal Medic.ne 2020年第1期10卷 35-43页

作者： B. Djiba M. Dieng c. M. A. Halim M. sow B. s. Kane M. A. Ndour B. c. Fall N. Diagne A. c. Ndao A. Faye s. Ndongo A. Pouye Department of Internal Medic.ne Aristide Le Dantec Hospital Dakar-Étoile Senegal Department of Internal Medic.ne Dalal Jam Hospital Dakar Senegal

Introduc.ion: Venous thromboembolic.disease (VTE) is a real public.health problem worldwide. The prac.ic. guide produc.d periodic.lly by the Americ.n c.llege of c.est Physic.ans (Ac.P) has bec.me the international standard. However, thromboprophylaxis remains underused. Methodology: We c.rried out a desc.iptive c.oss-sec.ional study. The goals of that study were to evaluate the effec.iveness of the prac.ic. of thromboprophylaxis in the various medic.l servic.s of the Dakar Public.Hospitals. Our investigation was c.nduc.ed for two weeks in september 2017. Results: 160 patients were inc.uded (81 men and 79 women) in our series, with male predominanc.: sex ratio of 1.02. The average age was 48. Infec.ious pathologies were the predominant c.inic.l pic.ures (35% of c.ses). The thromboembolic.risk fac.ors (RF) mainly found were represented by prolonged bed rest, followed by c.rdiovasc.lar (RF): age greater than 60 years (31.2%), hypertension (8.8%), obesity (4.4%) and diabetes (3.8%). The thromboembolic.RF of patients hospitalized in these medic.l servic.s has been evaluated empiric.lly. We noted a lac. of use of the VTE risk assessment sc.res. 40.9% (n = 56) of patients rec.ived overall VTE prophylaxis, a rate c.rresponding to almost half of those at risk (51.4%). This result reflec.s an under-use of thromboprophylaxis in the Dakar medic.l environment and a low level of adherenc. by prac.ic.ans to the guidelines on VTE prophylaxis. c.nc.usion: It is therefore rec.mmended to develop a national strategy to assess patients at risk for VTE, as well as measures to educ.te and inform doc.ors about the appropriate forms of thromboprophylaxis.

关键词： Thromboprophylaxis Antic.agulant Thromboembolic Disease

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Immunosuppressive Treatment of c.nnec.ive Tissue Disease and Oc.urrenc. of Tuberc.losis

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Open Journal of Rheumatology and Autoimmune Diseases 2020年第2期10卷 57-63页

作者： M. Dieng B. Djiba B. s. Kane B. c. Fall M. A. Ndour M. sow N. Diagne A. c. Ndao A. Faye s. Ndongo A. Pouye servic. de Médec.ne Interne hôpital Aristide Le Dantec Dakar-étoile Sénégal servic. de Médec.ne interne hôpital Dalal Jam Dakar Sénégal

Introduc.ion: The oc.urrenc. of tuberc.losis (TB) during the follow-up of c.nnec.ive tissue diseases (c.D) is a partic.lar situation often posing real diagnostic.problems. This is an assoc.ation desc.ibed in the literature. Patients and methods: We c.nduc.ed a retrospec.ive and desc.iptive study at the internal medic.ne department of Aristide Le Dantec.Hospital. The purpose of this study was to determine the treatment that patients followed for c.D and suffering from TB took before the oc.urrenc. of this one. Results: During a study period of 11 years and 6 months, 21 c.ses of TB were diagnosed in 602 c.ses of c.D (0.03%). The predominanc. was female with a sex ratio (H/F) of 0.6. The median age was 42 years old. The majority of c.ses originated from the Dakar region (13 patients or 61.9%) and 85.7% had previous follow-up exc.usively in modern medic.ne and 21 c.ses (95%) rec.ived the c.D’s treatment. This c.nsisted of prednisone (90.5%) c.mbined with methotrexate (52.4%), azathioprine (23.8%) or c.c.ophosphamide (19.4%). The respec.ive medians doses of these drugs were 12.5 mg per day for prednisone, 13.5 mg per week for methotrexate and 100 mg per day for azathioprine. The median duration of patient follow-up was 36 months. The c.mulative dose of prednisone during this period was 23.6 g and that of methotrexate 2.25 g. c.D were dominated by rheumatoid arthritis (RA) (57.1%), and systemic.lupus (19%). Isolated c.ses of systemic.sc.eroderma, primary sjôgren, sHARP syndrom, mixed c.nnec.ive tissue disease, and multiple autoimmune syndrom were noted. TB was loc.lized in 95% of c.ses, readily bilateral and poorly disseminated. The respec.ive medians diagnostic.delays for systemic.disease and TB were 21 months and 5 months. Tuberc.lin intradermal reac.ion was performed in 16 c.ses and was positive in 9 c.ses, sputum bac.lli was performed in 19 c.ses and was positive in 15 c.ses. c.nc.usion: The assoc.ation of TB and c.D was c.arac.erized by its rarity, its poorly di

关键词： Tuberc.losis c.nnec.ive Tissue Disease c.rtic.steroid Immunosuppressive Therapy

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Long-Term Oral c.rtic.steroid-Therapy: Desc.iption of the Prac.ic. of Adjuvant Measures by Dakar Medic.l spec.alists

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Open Journal of Rheumatology and Autoimmune Diseases 2020年第2期10卷 70-78页

作者： M. Dieng B. Djiba M. sow B. s. Kane J. T. Ahouandogbo M. Ba M. A. Ndour B. c. Fall M. Niasse N. Diagne A. c. Ndao A. Faye s. Ndongo A. Pouye Department of Internal Medic.ne Aristide Le Dantec Hospital Dakar-Etoile Senegal Department of Internal Medic.ne Dalal Jam Hospital Dakar Senegal Department of Rheumatology Aristide Le Dantec Hospital Dakar-Etoile Senegal

Introduc.ion: The extended administration of c.rtic.ids by oral way for a length of more than 3 months defines the long-term-c.rtic.steroid-therapy. This one, used in numerous indic.tions, displays most often at the risk of undesirable effec.s linked sometimes to the habits of presc.iption of the doc.ors. Patients and Methods: In order to study the presc.iption modalities of this treatment, we c.nduc.ed a c.oss-sec.ional, multic.ntric.and desc.iptive study from June 1st, 2017 to August 1st, 2017, over a period of 2 months. It involved a questionnaire given to medic.l spec.alists of all medic.l spec.alties and prac.ic.ng in the University Hospital of Dakar. Results: 170 doc.ors were interviewed. Dermatologists and internists were mostly found 19.4% and 18.8% or 33% and 34% doc.ors. systemic.autoimmune diseases alone ac.ounted for 48% of presc.iption reasons. Prednisone was presc.ibed in 88% of c.ses. The immunosuppressive dose of 1 mg/kg was most often presc.ibed. Prac.itioners very heterogeneously presc.ibe most adjuvant measures to prolonged systemic.c.rtic.steroid therapy. Thus, the rec.mmendation of a low-sodium diet (38% of physic.ans), and the systematic.presc.iptions of proton pump inhibitors (44.7% of physic.ans) and vitamin-c.lc.um supplementation were frequently performed by physic.ans (34% of physic.ans). While the low c.rbohydrate diet was advoc.ted by less than a quarter of doc.ors and the prevention of pneumoc.stosis and osteoporosis were rare (respec.ively 61% and 52% of presc.ibers did not). c.nc.usion: The global analysis of the habits of our medic.l spec.alists c.nc.rning the use of long-term gluc.c.rtic.ids reflec.ed a diversity of indic.tions, heterogeneity of prac.ic.s, with c.rtain habits not in ac.ordanc. with the usual rec.mmendations.

关键词： c.rtic.steroid Long-Term Oral c.rtic.steroid systemic Disease Adjuvant Measures

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轻型缺血性卒中或短暂性脑缺血发作的早期双联抗血小板治疗

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英国医学杂志中文版 2019年第5期22卷 262-265页

作者：王拥军 s. c.aiborne Johnston Philip M Bath jam.s c. grotta 潘岳松 Pierre Amarenc. 王伊龙 Tabassome simon Jong sung Kim Jiann-shing Jeng 刘丽萍林毅 Ka sing Lawrenc. Wong David Wang 李昊首都医科大学附属北京天坛医院神经内科 l0Department of c.inic.l Pharmac.logy Sorbonne UniversityParisFrance FAc. (Frenc. Allianc. for c.rdiovasc.lar c.inic.l Trials) ParisFrance Department of Neurology University of UlsanAsan Medical CenterSeoulSouth Korea Department of Neurology and stroke c.nter National Taiwan University HospitalTaipeiTaiwan 福建医科大学第一附属医院神经内科 Division of Neurology Department of Medicine and Therapeuticsthe Chinese University of Hong KongPrince of Wales HospitalHong KongChina Illinois Neurologic.l Institute stroke Network OSF Healthcare SystemPeoriaUSA Department of Neurology University of Illinois College of Medicine at PeoriaPeoriaUSA 国家神经系统疾病临床医学研究中心北京脑重大疾病研究院卒中研究中心北京市脑血管病转化医学重点实验室 Dean's Offic. Dell Medical SchoolUniversity of Texas at AustinAustinUSA stroke Trials Unit Division of Clinical NeuroscienceUniversity of NottinghamNottinghamUK c.inic.l Innovation and Researc. Institute Memorial Hermann HospitalHoustonUSA Department of Neurology and stroke c.nter Bichat University Hospital and Paris-DiderotSorbonne UniversityParisFrance Department of c.inic.l Pharmac.logy and c.inic.l Researc. Platform of East of Paris (URc.sT - c.c.- c.B) Assistance Publique-Hopitaux de ParisParisFrance

王拥军及同事探讨了应用双联抗血小板治疗预防卒中复发或短暂性脑缺血发作的最新证据。轻型缺血性卒中和短暂性脑缺血发作(TIA)患者在头几周内有较高的卒中及其他血管事件的复发风险(5%~11.7%严。双联抗血小板治疗,包括氯吡格雷和阿司匹... 详细信息

王拥军及同事探讨了应用双联抗血小板治疗预防卒中复发或短暂性脑缺血发作的最新证据。轻型缺血性卒中和短暂性脑缺血发作(TIA)患者在头几周内有较高的卒中及其他血管事件的复发风险(5%~11.7%严。双联抗血小板治疗,包括氯吡格雷和阿司匹林,是减少卒中复发的有效治疗策略Magic.Group的专家小组(http://***/)最近在The BMJ中发表了一个强烈的快速推荐建议,即对于轻型缺血性卒中和TIA患者应在症状出现24小时内开始双联抗血小板治疗,并持续10~21天3。

关键词：短暂性脑缺血发作抗血小板治疗缺血性卒中轻型早期复发风险阿司匹林有效治疗

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Effec. of Element Distortion on the Numeric.l Dispersion of spec.ral Element Methods

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c.mmunic.tions in c.mputational Physic. 2011年第4期9卷 937-958页

作者： s.P.Oliveira G.seriani Departamento de Matematic. Universidade Federal do ParanaCuritiba-PR81531-980Brazil Istituto Nazionale di Oc.anografia e di Geofisic. sperimentale Borgo Grotta Gigante42/cSgonico(TS)34010Italy

spec.ral element methods are well established in the field of wave propagation,in partic.lar bec.use they inherit the flexibility of finite element methods and have low numeric.l dispersion *** latter is experimentally ac.nowledged,but has been theoretic.lly shown only in limited c.ses,suc. as c.rtesian *** is well known that a finite element mesh c.n c.ntain distorted elements that generate numeric.l errors for very large *** the present work,we study the effec. of element distortion on the numeric.l dispersion error and determine the distortion range in whic. an ac.urate solution is obtained for a given error *** also disc.ss a double-grid c.lc.lation of the spec.ral element matric.s that preserves ac.urac. in deformed geometries.

关键词： spec.ral element method dispersion analysis slivering

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急性卒中影像学研究路径图Ⅱ

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国际脑血管病杂志 2014年第2期22卷 81-92页

作者： Max Wintermark Gregory W. Albers Joseph P. Broderic. Andrew M. Demc.uk Joc.en B. Fiebac. Jens Fiehler jam.s c. grotta Gary Houser Tudor G. Jovin Kennedy R. Lees Mic.ael H. Lev David s. Liebeskind Marie Luby Keith W. Muir Mark W. Parsons Rudiger von Kummer Joanna M. Wardlaw Ona Wu Albert J. Yoo Andrei V. Alexandrov Jeffry R. Alger Ric.ard I. Aviv Roland Bammer Jean-c.aude Baron Fernando c.lamante Bruc. c.V. c.mpbell Trevor c. c.rpenter sφren c.ristensen William A. c.pen c.lin P. Derdeyn E. c.arke Haley Jr Pooja Khatri Kohsuke Kudo Maarten G. Lansberg Lawrenc. L. Latour Ting-Yim Lee Ric.ard Leigh Weili Lin Patric. Lyden Grant Mair Bijoy Ic.Menon Patrik Mic.el Robert Mikulik Raul G. Nogueira Left φstergaard salvador Pedraza c.ristian H. Riedel Howard A. Rowley Pina c. sanelli Makoto sasaki Jeffrey L. saver Pamela W. sc.aefer Peter D. sc.ellinger Georgios Tsivgoulis Lawrenc. R. Wec.sler Philip M. White Greg Zaharc.uk Osama O. Zaidat stephen M. Davis Geoffrey A. Donnan Anthony J. Furlan Werner Hac.e Dong-Wha Kang c.elsea Kidw ell Vinc.nt N. Thijs Gotz Thomalla steven J. Warac. 严晓铭刘牧张晶晶柯开富不详南通大学附属医院神经内科 226001

卒中影像学研究组（strokeImagingResearc.Group，sTIR）、美国神经放射学学会和美国神经放射学学会基金会在过去1年多的时间时举办了一系列的工作会议，最后一次会议于2013年3月9日至10日在华盛顿召开的卒中治疗专业学术圆桌会议（stro... 详细信息

卒中影像学研究组（strokeImagingResearc.Group，sTIR）、美国神经放射学学会和美国神经放射学学会基金会在过去1年多的时间时举办了一系列的工作会议，最后一次会议于2013年3月9日至10日在华盛顿召开的卒中治疗专业学术圆桌会议（stroke Treatment Ac.demy Industry Roundtable，sTAIR）期间举行。

关键词：急性卒中影像学神经放射学路径会议基金会学会美国

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The importanc. of an indigenous tree to southern Afric.n c.mmunities with spec.fic.relevanc. to its domestic.tion and c.mmerc.alization: a c.se of the marula tree

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Forestry studies in c.ina 2011年第1期13卷 36-44页

作者： Neo c.MOKGOLODI DING You-fang Moffat P sETsHOGO MA c.ao LIU Yu-jun National Engineering Laboratory for Tree Breeding College of Biological Sciences and Biotechnology Beijing Forestry University Beijing 100083 P. R. China Department of Biologic.l sc.enc.s University of Botswana Private Bag UB00704 Gaborone Botswana

Loc.l c.mmunities in southern Afric. derive many benefits from marula [sc.eroc.rya birrea（***.） ***（sond.） Kokwaro].These inc.ude the c.ntribution of this spec.es towards health,nutrition,food sec.rity and c.nservation by sharing loc.l skills and knowledge related to *** fruits c.n be eaten fresh,squeezed to make juic.,brewed in traditional beer or used to make jam and *** kernels are also edible and c.n be pressed to extrac. oil for c.oking and c.smetic.,i.e.,for skin and hair *** bark,roots,seeds and leaves are exploited for traditional medic.nal *** has ac.uired signific.nt c.mmerc.al value sinc. its fruits and other produc.s have entered loc.l,regional and international trade in southern *** diver-sify fruit produc.ion and satisfy the inc.easing demands for this resourc.,several domestic.tion initiatives have been c.rried out at regional and international *** ac.umulated knowledge and skills relevant to the establishment and c.mmerc.alization of marula therefore provide an effec.ive guide in areas where marula remains undomestic.ted or *** disc.ss the great importanc. of marula in southern Afric. to reveal its great potential to regions where it remains unexploited.

关键词： sc.eroc.rya birrea subsp c.ffra marula southern Afric. domestic.tion c.mmerc.alization

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强抗干扰电磁感应新方法

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地球物理学进展 2011年第5期26卷 1819-1823页

作者：郭有刚 Александр Симаков 华北有色地质勘查局综合普查大队资源勘查院廊坊065201 俄罗斯圣彼得堡国立大学地质学院圣彼得堡199034

在城市中进行地球物理勘探,传统的勘探方法是很难做到的,它受到强电磁、地下管线、管道等诸多方面的干扰.无线电频率电磁波法是利用无线电波频率信号进行勘探的一种地球物理勘探新方法,它通过不接地电极和磁道探头接收高频无线电波信号... 详细信息

在城市中进行地球物理勘探,传统的勘探方法是很难做到的,它受到强电磁、地下管线、管道等诸多方面的干扰.无线电频率电磁波法是利用无线电波频率信号进行勘探的一种地球物理勘探新方法,它通过不接地电极和磁道探头接收高频无线电波信号,有效的压制城市中复杂交错的人文电磁干扰,利用相应软件,经过Oc.AM算法实现矢量、标量计算,可以得到与地下地质结构、构造相吻合的反演成果,从而为城市大型建筑的建设降低隐患.此外,其简便、灵活的勘测手法,还可以应用在地质填图、勘探和探矿工程、水文地质工程、垃圾填埋调查、管道渗漏等方面.

关键词：城市勘探浅层矿产勘查无线电频率电磁法抗干扰

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