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Revolutionizing diabetic retinopathy screening and management:The role of artificial intelligence and machine learning

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World Journal of Clinical Cases 2025年第5期13卷 1-12页

作者： Mona Mohamed Ibrahim Abdalla jaiprakash mohanraj Department of Human Biology School of MedicineInternational Medical UniversityBukit Jalil 57000Kuala LumpurMalaysia

Diabetic retinopathy(DR)remains a leading cause of vision impairment and blindness among individuals with diabetes,necessitating innovative approaches to screening and *** editorial explores the transformative potential of artificial intelligence(AI)and machine learning(ML)in revolutionizing DR *** and ML technologies have demonstrated remarkable advancements in enhancing the accuracy,efficiency,and accessibility of DR screening,helping to overcome barriers to early *** technologies leverage vast datasets to identify patterns and predict disease progression with unprecedented precision,enabling clinicians to make more informed ***,AI-driven solutions hold promise in personalizing management strategies for DR,incorpo-rating predictive analytics to tailor interventions and optimize treatment *** automating routine tasks,AI can reduce the burden on healthcare providers,allowing for a more focused allocation of resources towards complex patient *** review aims to evaluate the current advancements and applic-ations of AI and ML in DR screening,and to discuss the potential of these techno-logies in developing personalized management strategies,ultimately aiming to improve patient outcomes and reduce the global burden of *** integration of AI and ML in DR care represents a paradigm shift,offering a glimpse into the future of ophthalmic healthcare.

关键词： Diabetic retinopathy Artificial intelligence Machine learning Screening Management Predictive analytics Personalized medicine

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Adiponectin as a therapeutic target for diabetic foot ulcer

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World Journal of Diabetes 2023年第6期14卷 758-782页

作者： Mona Mohamed Ibrahim Abdalla jaiprakash mohanraj Sushela Devi Somanath Department of Physiology Human Biology DivisionSchool of MedicineInternational Medical UniversityKuala Lumpur 57000Malaysia Department of Biochemistry Human Biology DivisionSchool of MedicineInternational Medical UniversityKuala Lumpur 57000Malaysia Department of Microbiology School of MedicineInternational Medical UniversityKuala Lumpur 57000Malaysia

The global burden of diabetic foot ulcers(DFUs)is a significant public health concern,affecting millions of people *** wounds cause considerable suffering and have a high economic ***,there is a need for effective strategies to prevent and treat *** promising therapeutic approach is the use of adiponectin,a hormone primarily produced and secreted by adipose *** has demonstrated anti-inflammatory and antiatherogenic properties,and researchers have suggested its potential therapeutic applications in the treatment of *** have indicated that adiponectin can inhibit the production of pro-inflammatory cytokines,increase the production of vascular endothelial growth factor,a key mediator of angiogenesis,and inhibit the activation of the intrinsic apoptotic ***,adiponectin has been found to possess antioxidant properties and impact glucose metabolism,the immune system,extracellular matrix remodeling,and nerve *** objective of this review is to summarize the current state of research on the potential role of adiponectin in the treatment of DFUs and to identify areas where further research is needed in order to fully understand the effects of adiponectin on DFUs and to establish its safety and efficacy as a treatment for DFUs in the clinical *** will provide a deeper understanding of the underlying mechanisms of DFUs that can aid in the development of new and more effective treatment strategies.

关键词： Diabetic foot ulcer Adiponectin Anti-inflammatory Adipose tissue Antioxidants Wound healing

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