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Effect of the Melatonin on Morning Blood Pressure Surge and Norepinephrine Endovenous Infusion in Healthy Volunteers

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International Journal of Clinical Medicine 2015年第7期6卷 458-464页

作者： jaime Carranza-Madrigal José Miguel cervantes-Alfaro Sonia María López-Correa Escuela de Enfermería y Salud Pública Universidad Michoacana de San Nicolás de Hidalgo Morelia México División de Estudios de Postgrado Facultad de Ciencias Médicas y Biológicas “Dr. Ignacio Chávez” Universidad Michoacana de San Nicolás de Hidalgo Morelia México

Melatonin, the pineal gland hormone, has been considered as a central hypotension factor. However their roles in the regulation of the human blood pressure and its possible use as antihyper-tensive drug have not been fully determined. The objective of this trial was to determine the effect of melatonin on blood pressure morning increase and a peripheral vasoconstriction challenge in healthy volunteers. Twelve healthy male volunteers were included in a prospective, comparative, randomized, crossover trial in which changes on blood pressure (BP) and heart rate (HR) after the first morning orthostatism and endovenous norepinephrine (NE) infusion were measured one hour after the administration of placebo (PL) or 10 mg of melatonin in double blind conditions. Melatonin blunted the effects of the first orthostatism on BP and HR. Melatonin also reduces the pressor effect of NA. One concludes that melatonin has central and peripheral hypotensive effects that support a potential role of this hormone in cardiovascular therapeutics.

关键词： Blood Pressure Hypertension Melatonin Norepinephrine Orthostatism

Gut microbiota in a population highly affected by obesity and type 2 diabetes and susceptibility to COVID-19

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World Journal of Gastroenterology 2021年第41期27卷 7065-7079页

作者： jaime García-Mena Karina Corona-cervantes Daniel Cuervo-Zanatta Tizziani Benitez-Guerrero JuanManuel Vélez-Ixta Norma Gabriela Zavala-Torres Loan Edel Villalobos-Flores Fernando Hernández-Quiroz Claudia Perez-Cruz Selvasankar Murugesan Fernando Guadalupe Bastida-González Paola Berenice Zárate-Segura departamento de Genética y Biología Molecular Centro de Investigación y de Estudios Avanzados del Instituto Politécnico NacionalMexico City 07360CDMXMexico departamento de Genética y Biología Molecular and departamento de Farmacología Centro de Investigación y de Estudios Avanzados del Instituto Politécnico NacionalMexico City 07360CDMXMexico departamento de Farmacología Centro de Investigación y de Estudios Avanzados del Instituto Politécnico NacionalMexico City 07360CDMXMexico department of Mother and Child Health SIDRA MedicineDoha 26999Qatar Laboratorio Estatal de Salud Pública del Estado de México ISEMToluca de Lerdo 50180Estado de MéxicoMexico Escuela Superior de Medicina Instituto Politécnico NacionalMexico City 11340CDMXMexico

Coronavirus disease 2019(COVID-19)is a disease produced by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)and it is currently causing a catastrophic pandemic affecting humans *** disease has been lethal for approximately 3.12 million people around the world since January ***,among the most affected countries,Mexico ranks third in deaths after the United States of America and *** the high number of deceased people might also be explained by social aspects and lifestyle customs in Mexico,there is a relationship between this high proportion of deaths and comorbidities such as high blood pressure(HBP),type 2 diabetes,obesity,and metabolic *** official epidemiological figures reported by the Mexican government have indicated that 18.4%of the population suffers from HBP,close to 10.3%of adults suffer from type 2 diabetes,and approximately 36.1%of the population suffers from *** in the gut microbiota(GM)have been associated with these diseases and with COVID-19 severity,presumably due to inflammatory *** data about the association between GM dysbiosis and metabolic diseases could suggest that the high levels of susceptibility to SARSCoV-2 infection and COVID-19 morbidity in the Mexican population are primarily due to the prevalence of type 2 diabetes,obesity,and metabolic syndrome.

关键词： SARS-CoV-2 COVID-19 High blood pressure Hypertension Type 2 diabetes Obesity Metabolic syndrome Gut microbiota Immunity

Population dynamics of three lizard species from the genus Sceloporus:short-term changes in demographic parameters

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Integrative Zoology 2019年第6期14卷 542-560页

作者： Selene VARGAS-GARCÍA Víctor ARGAEZ Israel SOLANO-ZAVALETA J.jaime ZÚÑIGA-VEGA Graduate Program in Biological Sciences National Autonomous University of MexicoUniversity CityMexico CityMéxico department of Ecology and Natural Resources Faculty of SciencesNational Autonomous University of MexicoUniversity CityMexico CityMéxico.

Most demographic studies focus on numerical changes that occur within populations across ***,typically studies at an interannual scale do not provide information on the particular times of the year(particular months or seasons)when rates of survival,recruitment,or migration increase or decrease due to physiological,behavioral or ecological *** monthly or seasonal changes in demographic parameters may lead to substantial variations in population *** this study,we collected capture-mark-recapture data on 3 species of lizards of the genus Sceloporus(Sceloporus torquatus,Sceloporus grammicus and Sceloporus megalepidurus)found in ecologically similar habitats to examine potential changes in demographic rates among 3 different climatic seasons:rainy,cold-dry and warm-dry *** tested different hypotheses about the effect of these seasons on survival,recruitment of new adults,and temporary *** found that during the season with severe thermal constraints,the cold-dry season,survival of *** decreased *** also detected a considerable increase in the recruitment rate of *** during the rainy season,when these lizards are establishing territories and finding *** contrast,we found no evidence of intra-annual changes in the rate of temporary *** addition,we calculated abundance and population growth rates for each species and for each *** study represents a significant contribution to the understanding of intra-annual demographic variation in lizards.

关键词： abundance recruitment Sceloporus lizards survival temporary emigration

Sperm Quality in Holstein Bulls Friesian and Brahmans of Frozen Semen Commercially

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Open Journal of Animal Sciences 2015年第3期5卷 229-231页

作者： Alejandro Córdova-Izquierdo Gustavo Ruiz-Lang Román Espinosa-cervantes Adrían Emmanuel Iglesias-Reyes Maximino Méndez-Mendoza Rubén Huerta-Crispín Abel Edmundo Villa-Mancera Ma. de Lourdes Juárez-Mosqueda Pedro Sánchez-Aparicio jaime Olivares-Pérez Juan Eulogio Guerra-Liera Gerardo Cansino-Arroyo departamento de Producción Agrícola y Animal Universidad Autónoma Metropolitana Unidad Xochimilco México D.F. México Facultad de Veterinaria Benemérita Universidad Autónoma de Puebla Puebla México departamento de Morfología FMVZ-UNAM México D.F. México Facultad de Veterinaria Universidad Autónoma del Estado de México Toluca México Unidad Académica de Medicina Veterinaria y Zootecnia Universidad Autónoma de Guerrero Guerrero México Facultad de Agronomía Universidad Autónoma de Sinaloa Culiacán México División Académica de Ciencias Agropecuarias Universidad Juárez Autónoma de Tabasco Villahermosa México

The aim of this study was to assess sperm quality (motility, viability and acrosomal integrity) sperm from commercially frozen semen straws two breeds of bulls Bos taurus (holstein Frisian) and Bos indicus (Brahman). 9 commercial straws 0.5 ml of Holstein bull semen and 9 Brahman bull were thawed, they were kept for two hours at room temperature and motility, viability and acrosomal integrity (NAR) was assessed. The results were 30% motility, viability 40% and 30% of NAR in the Holstein breed. Brahma race for motility 40%, 50% and 40% viability was obtained NAR. In conclusion, according to the results of the variables analyzed, the Brahman breed in sperm quality was better than the Holstein breed;however, the results of both races meet minimum standards of quality sperm for use in artificial insemination (AI) field level.

关键词： Semen Thawed Bulls Frozen Semen Sperm Quality