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将南极带回家——一次虚拟探险将极地科学带给学生，并让家长走进学校

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中国科技教育 2012年第5期 38-42页

作者： Juanita Constible Lauren Williams jaime Faure Richard E. Lee, Jr. 凡霞(翻译)

当你想象南极有哪些神奇的生物时，你脑海里浮现的肯定不会是一只昆虫。但是，正是这种不太可能浮现的动物和一支南极科学探险队，构成了此次学习活动的基础，这项活动为从幼儿园到6年级的学习都创建了一个学习社区，并拓展到课外。

关键词：探险队南极科学学生虚拟回家学校家长

再谈闪光刺激方法学：新版欧洲脑电图室视觉刺激方法

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中华神经科杂志 2014年第4期47卷 273-277页

作者： Dorothee Kasteleijn-Nolst Trenite Guido Rubboli Edouard Hirsch Antonio Martins da Silva Stefano Seri Arnold Wilkins jaime Parra Athanasios Covanis Maurizio Elia 刘永红(译) 张文娟(译) 来江(译) 不详第四军医大学西京医院神经内科脑电监测中心西安710032

间断性闪光刺激(IPS)是脑电图监测中常用的检测方法,旨在发现儿童及成人异常癫痫样放电对闪光的敏感性(即光敏感性).但在临床实践中,不同的国家以及不同的脑电图室采用的IPS方法不同,导致结果有所差异.我们认为应该建立标准的检测方法,... 详细信息

间断性闪光刺激(IPS)是脑电图监测中常用的检测方法,旨在发现儿童及成人异常癫痫样放电对闪光的敏感性(即光敏感性).但在临床实践中,不同的国家以及不同的脑电图室采用的IPS方法不同,导致结果有所差异.我们认为应该建立标准的检测方法,从而能够可重复地定性和定量检测光敏感性,更利于监测和识别癫痫和光敏感性患者.与1999年发表的方法相比较,新方法不仅增加了内容,而且对IPS检测技术以及相关的操作原理进行了详述.为了提高有效性及实用性,该方法通过6年的欧洲神经病学及癫痫专家实践反馈并且反复讨论形成了共识.

关键词：脑电图监测闪光刺激刺激方法欧洲方法学癫痫样放电光敏感性视觉

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设计师采访

中国建筑装饰装修 2011年第4期 108-112页

作者：金鲜花卢筱艺李冬 Didier Ryan jaime Magén Pardo Kim Herforth Nielsen GID国际建筑一部韩国忠南大学华南理工大学广东省建筑设计研究院燕山大学艺术与设计学院城市空间与人居环境设计研究所英国Undercurrent事务所 MAGEN ARQUITECTOS事务所西班牙亚拉贡建筑协会 3XN事务所

金鲜花 GID国际建筑一部设计总监韩国忠南大学建筑设计硕士《中装》:您所见到过的建筑中,对哪座建筑的屋顶设计印象最深?金:日本大板的NambaPark。屋顶花园为建筑的重要一部分,绿化屋顶设计让建筑大隐于自然,商业功能与屋顶花园相... 详细信息

金鲜花 GID国际建筑一部设计总监韩国忠南大学建筑设计硕士《中装》:您所见到过的建筑中,对哪座建筑的屋顶设计印象最深?金:日本大板的NambaPark。屋顶花园为建筑的重要一部分,绿化屋顶设计让建筑大隐于自然,商业功能与屋顶花园相辅相成,提供给人们愉悦的购物活动。

关键词：屋顶花园建筑物使用者设计师建筑屋顶第五立面建筑节能屋顶空间柯布西耶

Upper Blepharoplasty Scar and Patient Satisfaction Evaluation in a Plastic Surgery Center in Mexico

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Journal of Biosciences and Medicines 2020年第6期8卷 77-88页

作者： Victor Hugo Avalos Gómez jaime Aron García Espinoza José Carlos Martínez López Carlos Illich Navarro Delgadillo Blanca Yadira Arámbula Sánchez Alejandro Costa Dulche Cuahutemoc Márquez Espriella Esteban Israel Campos Serna Division of Plastic and Reconstructive Surgery Hospital Central Sur de Alta Especialidad de Petróleos Mexicanos Mexico City Mexico

Background: Eyes are one of the most important facial features, their appearance being associated with state of mind, age and beauty. Therefore, upper blepharoplasty is one of the most common procedures performed in plastic surgery. Standardized tools allow for measurement of outcomes through patient satisfaction and surgeon experience. Objectives: Our objective was to measure the satisfaction index and scar quality of patients who underwent upper blepharoplasty using the Patient-reported Outcome Measure Questionnaire (PROM-Q) and Patient and Observer Scar Assessment Scale (POSAS). Methods: A retrospective review of patients that underwent upper blepharoplasty in our institution was performed. We included those with a preoperative anthropometric analysis, standardized incision markings (developed in our center), same operative technique and a 3-month postoperative evaluation with PROM-Q and POSAS. The sample for this study consists of 67 patients, all of them operated between January 1 2019 and June 30 2019 at the Department of Plastic Surgery, South Central High Specialty Hospital, Pemex, Mexico City, Mexico. Results: A total of 67 patients were included, 73% female and 27% male. The most frequent indication for surgery was functional visual symptoms. The index of PROM-Q at 3 months demonstrated an increased satisfaction above 90%, and the evaluation with POSAS reported an almost imperceptible scar. Conclusion: Evaluating outcomes with objective tools provides data useful to improve the surgical protocols of patients subjecting to aesthetic procedures.

关键词： Upper Blepharoplasty Satisfaction Index PROM-Q Quality of Life Scar

Rare germline copy number variants in colorectal cancer predisposition characterized by exome sequencing analysis

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Journal of Genetics and Genomics 2018年第1期45卷 41-45页

作者： Sebastia Franch-Exposito Clara Esteban-Jurado Pilar Garre Isabel Quintanilla Saray Duran-Sanchon Marcos Diaz-Gay Laia Bonjoch Miriam Cuatrecasas Esther Samper Jenifer Munoz Teresa Ocana Sabela Carballal Maria Lopez-Ceron Antoni Castells Maria Vila-Casadesus Sophia Derdak Steven Laurie Sergi Beltran jaime carvajal Luis Bujanda Clara Ruiz-Ponte Jordi Camps Meritxell Gironella Juan Jose Lozano Francesc Balaguer Joaquin Cubiella Trinidad Caldes Sergi Castellvi-Bel Gastroenterology Department Hospital Clinic de Barcelona August Pi i Sunyer Biomedical Research Institute CIBER of Hepatic and Digestive Diseases University of Barcelona Barcelona 08036 Spain Molecular Oncology Laboratory Hospital Clinico San Carlos Health Research Institute of the Hospital Clinico San Carlos Madrid 28040 Spain Department of Pathology Hospital Clinic de Barcelona Barcelona 08036 Spain EPICOLON consortium Bioinformatics Platform CIBER of Hepatic and Digestive Diseases Barcelona 08036 Spain National Center of Genomic Analysis Science Park of Barcelona Barcelona 08028 Spain Andalusian Developmental Biology Institute CSIC-Pablo de Olavide University-Andalusian Regional Government SeviUa 41013 Spain Gastroenterology Department Hospital Donostia-Biodonostia Institute CIBER of Hepatic and Digestive Diseases University of the Basque Country (UPV/EHU) San Sebastian 20080 Spain Galician Public Foundation of Genomic Medicine (FPGMX) CIBER of Rare Diseases Genomics Medicine Group Hospital Clinico Universitario University of Santiago de Compostela Santiago de Cornpostela 15706 Spain Castroenterology Department Complexo Hospitalario Universitario de Ourense Ourense Biomedical Research Institute Ourense 32005 Spain

Colorectal cancer （CRC） is one of the most common neoplasms and an important cause of mortality worldwide （http：//globocan. ***]）. Approximately 35% of the variation in CRC susceptibility is likely due to heritable factors （Lichtenstein et al., 2000}. Genetic variations in the human genome include single nucleotide variants （SNVs）, short insertions and deletions, and larger structural variants resulting in gain or loss of genomic DNA larger than 1 kb, such as copy number variants （CNVs）. Leaving aside the importance of CNVs in sporadic tumor development, these variants can also be present in the germline DNA of healthy individuals from the general population and be considered polymorphic.

关键词： WHOLE-EXOME GENE

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Flexible distributed feedback lasers based on nanoimprinted cellulose diacetate with efficient multiple wavelength lasing

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npj Flexible Electronics 2019年第1期3卷 142-148页

作者： José R.Castro Smirnov Ahmad Sousaraei Manuel R.Osorio Santiago Casado jaime J.Hernández Longfei Wu Qi Zhang Ruidong Xia Daniel Granados Reinhold Wannemacher Isabel Rodriguez Juan Cabanillas-Gonzalez Madrid Institute for Advanced Studies in Nanoscience IMDEA NanocienciaCalle Faraday 9Ciudad Universitaria de Cantoblanco28049 MadridSpain Key Laboratory for Organic Electronics and Information Displays and Institute of Advanced Materials National Jiangsu Synergistic Innovation Center for Advanced Materials(SICAM)Nanjing University of Posts and Telecommunications9 Wenyuan RoadNanjing 210046PR China

Here we present the assembly of novel transparent all-polymer distributed feedback(DFB)*** and highly transparent cellulose diacetate(CdA)was employed as substrate on which gratings with different periods were engraved by thermal nanoimprinting with high *** luminescent conjugated polymers(CP),poly(9,9-dioctylfluorene)(PFO),poly(9,9-dioctylfluorene-alt-benzothiadiazole)(F8BT),and a blend of F8BT and poly(3-hexylthiophene)-poly(9,9-dioctylfluorene-altbenzothiadiazole)(P3HT:F8BT)were deposited by spin coating onto the nanostructured plastic surfaces,giving rise to perpendicular single-mode lasing emission in the blue,green,and red wavelength ranges,*** lasers show linewidths below 1 nm and low thresholds(≈6μJcm^(−2) for blue and red lasing emission),comparable to other state-of-the-art lasers obtained from similar optical gain materials on rigid *** followed strategy is scalable and versatile,enabling the development of large area nanoimprinted DFB lasers(>1cm^(2))on plastic,which is highly relevant for applications in various markets.

关键词： lasers lasing transparent

Marine turtle hatchlings use multiple sensory cues to orient their crawling towards the sea:biological and conservation policy implications

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Advances in Bioscience and Biotechnology 2011年第2期2卷 47-51页

作者： Alma Lilia Fuentes-Farias Gabriel Gutierrez-Ospina Esperanza Melendez Herrera Veronica Camarena-Ramirez Gerardo Ochoa-Tovar Julieta Mendoza-Torreblanca Armida Baez-Saldana Raquel Martinez-Mendez jaime Urrutia-Fucugauchi Maria Luisa Garcia Zepeda Laboratorio de Ecofisiologia Facultad de BiologiaUniversidad Michoacana de San Nicolas de HidalgoCiudad UniversitariaMorelia MichoacanMexico58230 Laboratorio de Biologia de Sistemas Instituto de Investigaciones BiomedicasUniversidad Nacional Autonoma de MexicoCiudad UniversitariaMexico D.F.04510 Laboratorio de Paleomagnetismo Instituto de GeofisicaUniversidad Nacional Autonoma de MexicoCiudad UniversitariaMexico D.F.04510 Laboratorio de Paleontologia Facultad de BiologiaUniversidad Michoacana de San Nicolas de HidalgoCiudad UniversitariaMorelia MichoacanMexico58230 Laboratorio de Neuromorfometría Instituto Nacional de PediatríaMéxico D.F.04530

The ability of sea turtle hatchlings to find the seashore soon after hatching is thought to be exclusively dependent upon visual information. Target-oriented movements in most vertebrates, however, relay on combining information gathered through different sensory systems. Hence, in this work, we investigated whether olfactory and/or magnetic information might complement visual cues during hatchling’s seaward crawling. Acute olfactory deprivation and distorted magnetic sensation in visually competent hatchlings resulted in a scattering of seaward crawling routes among cardinal points, some of them being different from those strongly preferred by control hatchlings. In addition, blindfolded hatchlings also displayed a striking misrouting while crawling on the beach surface in spite of having intact olfactory and magnetic senses. Together these results support the notion that visual information is crucial for seaward crawling, but also that olfactory and magnetic information complement visual cues when turtle hatchlings display this behavior. Hence, the present observations suggest that multisensory cues are used by turtle hatchlings while crawling towards the sea. This work also has important implications on the design of species conservation measures and policies. In the near future, efforts must be made to identify and preserve the local natural sources of odors and magnetic cues, in addition to preventing the perturbing effects of artificial lighting on adult and hatchling turtle crawling behavior.

关键词： Olfaction Magnetoreception Vision Chelonia aggasizi Seaward orientation Reptiles Intermodal interactions Multisensory integration

Intertwined leukocyte balances in tumours and peripheral blood as robust predictors of right and left colorectal cancer survival

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World Journal of Gastrointestinal Oncology 2022年第1期14卷 295-318页

作者： Ramón Cantero-Cid Karla Marina Montalbán-Hernández Jenny Guevara Alejandro Pascual-Iglesias Elisa Pulido JoséCarlos Casalvilla Cristóbal Marcano Cristina Barragán Serrano jaime Valentín Gloria Cristina Bonel-Pérez JoséAvendaño-Ortiz Verónica Terrón Roberto Lozano-Rodríguez Alejandro Martín-Quirós Elvira Marín Eva Pena Laura Guerra-Pastrián Eduardo López-Collazo Luis Augusto Aguirre Tumor Immunology Laboratory The Innate Immune Response GroupHospital La Paz Institute for Health Research(IdiPAZ)Madrid 28046Spain Digestive Surgery Service La Paz University HospitalMadrid 28046Spain Emergency Department and Emergent Pathology Research Group Hospital La Paz Institute for Health Research(IdiPAZ)Madrid 28046Spain Pathologic Anatomy Service Hospital La PazMadrid 28046Spain

BACKGROUND Colorectal cancer(CRC)accounts for 9.4%of overall cancer deaths,ranking second after lung *** the large number of factors tested to predict their outcome,most patients with similar variables show big differences in ***,right-sided CRC(RCRC)and left-sided CRC(LCRC)patients exhibit large differences in outcome after surgical intervention as assessed by preoperative blood leukocyte *** hypothesised that stronger indexes than circulating(blood)leukocyte ratios to predict RCRC and LCRC patient outcomes will result from combining both circulating and infiltrated(tumour/peritumour fixed tissues)concentrations of *** To seek variables involving leukocyte balances in peripheral blood and tumour tissues and to predict the outcome of CRC *** Sixty-five patients diagnosed with colon adenocarcinoma by the Digestive Surgery Service of the La Paz University Hospital(Madrid,Spain)were enrolled in this study:43 with RCRC and 22 with *** were followed-up from January 2017 to March 2021 to record overall survival(OS)and recurrence-free survival(RFS)after surgical *** concentrations in peripheral blood were determined by routine laboratory ***-fixed samples of tumour and peritumoural tissues were assessed for leukocyte concentrations by immunohistochemical detection of CD4,CD8,and CD14 marker *** of leukocyte concentration in blood and tissues were calculated and evaluated for their predictor values for OS and RFS with Spearman correlations and Cox univariate and multivariate proportional hazards regression,followed by the calculation of the receiver-operating characteristic and area under the curve(AUC)and the determination of Youden’s optimal cutoff values for those variables that significantly correlated with either RCRC or LCRC patient *** patients from the cohort were randomly assigned to modelling and validation sets,and clinician-friendly nomogra

关键词： Left colorectal cancer Leukocyte ratios Prognostic variables Recurrence-free survival Right colorectal cancer Overall survival

PERCUTANEOUS MANIPULATION OF INTRACARDIAC CATHETERS:RETRIEVAL,UNKNOTTING,REPOSITIONING,AND STRIPPING

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中国介入心脏病学杂志 1998年第4期6卷 188-188页

作者： jaime Tisnado Uma Prasad Janice Newsome Michael Ko Medical College of Virginia Hospitals RichmondVirginiaUSA 23298-0615

Puroose:Intracardiac embolization of catheter fragments,andiatrogenic,and other foreign bodies,such as stents,intracardiacformation of knots in catheters,malpositioning of intracardiaccatheters,and thrombi formation in intracardiac catheters arc seriouscomplications of catbeterization techniques,associated with highmorbidity and *** and Metbods:We performed percutaneous retrieval ofintracardiac catheters and iatrogenic foreign bodies(n=40),unknottingof catheter knots(n=4),repositioning of malpositioned catheters(n=31),and stripping of catheters(n=25),in 100 adults and *** equipment used included:retrieval baskets,retrievalwire loops,deflector wires,retrieval forceps,and differentangiographic catheters,alone or in ***:Retrieval of catheter fragments and iatrogenic foreign bodieswas successful in 38 *** were 3 failures:an IVC filter,acatheter,ans a Wallstent,lodged in the right *** ofcatheter knots,repositioning of misplaced catheters,and stripping ofcatheters was successful in all *** were no *** complications were ***:These procedures are quick,safe,and effective tomanage potentially serious complications of percutaneouscatheterization *** and other central catheters andports can be functional for longer periods.A major operation to solvethese problems,which may include open heart surgery,is avoided.

关键词： retrieval stripping alone Retrieval potentially mortality children Minor longer quick

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