检索结果-南通市图书馆

World Journal of Clinical Cases 2021年第15期9卷 3716-3725页

作者： Paulina F Toledo Zoltan Berger Laura Carreño Gonzalo Cardenas jaime castillo Omar Orellana Department of Gastroenterology Hospital Clinico Universidad de ChileSantiago 834456IndependenciaChile Department of Internal Medicine Section GastroenterologyHospital Clinico Universidad de ChileSantiago 834456IndependenciaChile Department of Pathology Hospital Clínico de la Universidad de ChileSantiago 834456IndependenciaChile Department of Radiology Hospital Clínico Universidad de ChileSantiago 834456IndependenciaChile Department of Surgery Hospital Clínico Universidad de ChileSantiago 834456IndependenciaChile

BACKGROUND Sarcomatoid carcinoma of the pancreas(SCP)is a rare type of pancreatic neoplasm,and only a few cases have been described in the ***,it is composed mostly of atypical spindle cells with apparent sarcomatous *** SUMMARY This is a report of a 61-year-old Chilean woman who underwent medical investigation for acute abdominal *** tomography identified a solid tumor in the tail of the pancreas with features suspicious of ***-bloc distal pancreatectomy and splenectomy were performed to excise the *** and immunohistochemistry were confirmatory of sarcomatoid carcinoma with lymphovascular *** surgery,the patient did not receive *** studies indicate a poor prognosis for this type of ***,our patient has survived for 35 mo with no recurrence to *** The case presented herein is a patient with an SCP with a rare presentation and long-term survival after surgery despite not receiving adjuvant chemotherapy.

关键词： Pancreatic neoplasms Sarcomatoid carcinoma Pancreatic ductal carcinoma Survival Abdominal pain Case report

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

休闲食品行业可持续消费的商业模式创新研究

中国食品 2024年第16期 126-128页

作者：阳欢 jaime T.Ballena IV 菲律宾圣路易斯大学

随着社会的进步和消费者环保意识的增强,可持续消费已逐渐成为休闲食品行业的重要发展方向。休闲食品行业可持续消费的商业模式创新不仅有助于提升企业的社会形象,开发出更符合市场需求的产品,提高品牌忠诚度,进而增加市场份额和销售额... 详细信息

随着社会的进步和消费者环保意识的增强,可持续消费已逐渐成为休闲食品行业的重要发展方向。休闲食品行业可持续消费的商业模式创新不仅有助于提升企业的社会形象,开发出更符合市场需求的产品,提高品牌忠诚度,进而增加市场份额和销售额,还有助于减少对环境的负面影响,引导整个行业朝着更加健康、环保和可持续的方向发展,推动整个行业的进步。为此,本文分析了休闲食品行业的现状及发展趋势,阐述了可持续消费的重要性和紧迫性,并从产品创新、销售模式创新、供应链创新和品牌形象创新等方面,详细论述了休闲食品行业如何通过商业模式创新实现可持续消费,从而促进经济、环境和社会效益的和谐统一。

关键词：商业模式创新品牌忠诚度休闲食品行业符合市场需求可持续消费供应链创新和谐统一品牌形象

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

长飞光纤产业大楼

建筑实践 2024年第4期 170-171页

作者：李晓梅刘经彦 jaime Gimeno 晋思建筑设计事务所

关键词：

人工智能数据采集在慢性乙型肝炎患者真实世界研究中的应用

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

暨南大学学报（自然科学与医学版） 2024年第1期45卷 77-83页

作者：周晓梅曾涛廖莹颖张一博李青海 jaime Smith 张麟王超崇雨田李新华中山大学附属第三医院信息中心广东广州510630 中山大学附属第三医院感染性疾病科∥广东省肝病重点实验室广东广州510630 广东精点数据科技股份有限公司广东广州510635 精鼎医药研究开发(上海)有限公司上海200120

目的:开发一套慢性乙型肝炎(乙肝)的人工智能(AI)数据采集工具,以解决传统的多中心数据采集效率低下的问题。方法:基于国际通用的数据标准,将AI的文字识别和自然语言处理应用于慢性乙肝真实世界队列研究数据采集,实现多种格式数据(包括... 详细信息

目的:开发一套慢性乙型肝炎(乙肝)的人工智能(AI)数据采集工具,以解决传统的多中心数据采集效率低下的问题。方法:基于国际通用的数据标准,将AI的文字识别和自然语言处理应用于慢性乙肝真实世界队列研究数据采集,实现多种格式数据(包括图片格式的原始数据)的电子化采集、结构化处理,随后自动将数据填入研究电子数据采集(REDCap)系统中的电子病历报告表(eCRF)。结果:AI工具辅助数据采集与纯人工数据采集具有相同的平均准确率,均达到98.66%(P=0.23),但前者所需时间减少75.49%(P<0.05)。结论:本研究开发的AI数据采集工具可显著提高研究数据采集效率,为真实世界研究数据采集提供了新的模式。

关键词：数据采集慢性乙型肝炎人工智能(AI) 自然语言处理文字识别

Self-assembled vesicle–colloid hybrid swimmers:Non-reciprocal strokes with reciprocal actuation

在线全文

学校读者我要写书评

暂无评论

Chinese Physics B 2020年第6期29卷 30-36页

作者： jaime Agudo-Canalejo Babak Nasouri Max Planck Institute for Dynamics and Self-Organization(MPIDS) 37077 GoettingenGermany

We consider a self-assembled hybrid system,composed of a bilayer vesicle to which a number of colloids are *** on known results of membrane curvature elasticity,we predict that,for sufficiently deflated prolate vesicles,the colloids can self-assemble into a ring at a finite distance away from the vesicle equator,thus breaking the up–down symmetry in the *** the relative variation of the position of the colloidal ring along the vesicle endows the system with an effective elasticity,periodic cycles of inflation and deflation can lead to non-reciprocal shape changes of the vesicle–colloid hybrid,allowing it to swim in a low Reynolds number environment under reciprocal *** design several actuation protocols that allow control over the swimming direction.

关键词： vesicles colloids microswimmers curvature

在线全文

学校读者我要写书评

暂无评论

巴特罗公寓楼梯与中庭室内设计

城市环境设计 2024年第1期147卷 24-27页

作者： Javier villar jaime Fernandez Calvache Gorka Beita Zarandona David Minton Albero Mila Dimitrovska Kimio Suzuki(CG) IMAGENSUBLIMINAL

本项目是对高迪在巴特罗公寓中对地中海光线的天才使用的致敬。巴特罗公寓8层通高的中庭能够获取自然光，并将其均匀分布在建筑的各个角落，而在这个项目中，这种光线的垂直传递是在原有应急楼梯的8层封闭空间内进行的，使用一系列悬挂...

本项目是对高迪在巴特罗公寓中对地中海光线的天才使用的致敬。巴特罗公寓8层通高的中庭能够获取自然光，并将其均匀分布在建筑的各个角落，而在这个项目中，这种光线的垂直传递是在原有应急楼梯的8层封闭空间内进行的，使用一系列悬挂式铝板来捕捉光线（在这里是人造光），目的是从明亮的屋顶到地下黑暗深处的旧煤窑创造一系列不断变化的体验。

关键词：

来源：博看期刊

Pancreatic biomarkers:Could they be the answer?

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2014年第24期20卷 7819-7829页

作者： Angela Lamarca jaime Feliu Department of Medical Oncology The Christie NHS Foundation TrustManchester M20 4BXUnited Kingdom Department of Medical Oncology La Paz University Hospital28046 MadridSpain

Pancreatic ductal adenocarcinoma(PDA)is known for its poor *** of the patients are diagnosed with advanced stages,when no curative treatment is ***,despite extensive clinical research on PDA,the median overall survival remains *** delay and primary chemo-resistance due to its intrinsic biological nature may explain the challenges to improve our *** knowledge about the molecular biology of PDA has exponentially increased during the last decades and its use for the development of biomarkers could help to reach better results in the clinical *** biomarkers could be the clue for the improvement in PDA clinical research by earlier detection strategies with diagnostic biomarkers,and by an individualization of treatment approach with prognostic and predictive *** review summarizes the current knowledge about the molecular biology of PDA and the status of the most important prognostic and predictive biomarkers.

关键词： Pancreatic adenocarcinoma Biomarkers Diagnosis Prognostic Predictive Treatment

Obstructive uropathy: Overview of the pathogenesis, etiology and management of a prevalent cause of acute kidney injury

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Nephrology 2024年第2期13卷 5-15页

作者： Xabier Pérez-Aizpurua Ramiro Cabello Benavente Gonzalo Bueno Serrano JoséMaría Alcázar Peral Blanca Gómez-Jordana Mañas jaime Tufet i Jaumot Joaquín Ruiz de Castroviejo Blanco Felipe Osorio Ospina Carmen Gonzalez-Enguita Department of Urology Hospital Universitario Fundación Jiménez DíazMadrid 28015MadridSpain

Obstructive uropathy is defined as the structural or functional interruption of urinary outflow at any level in the urinary *** is regarded as one of the most prevalent causes of acute kidney injury(AKI),accounting for 5%–10%of *** severe obstruction of the urinary tract is a potentially threatening situation for the kidneys and therefore requires prompt identification and management to relieve *** aim of the present article is to review and synthesize available evidence on obstructive uropathy,providing a clinical guideline for clinicians.A literature review on obstructive uropathy in the context of AKI was performed,focusing on the least clarified aspects regarding diagnosis and *** literature searching was conducted in English and top-level evidence articles including systematic reviews,metanalyses and large series were *** obstruction of the urinary tract is a diagnostic and therapeutical challenge that may lead to important clinical complications together with direct structural and hemodynamic damage to the *** recognition of the leading cause and its exact location is essential to ensure prompt urinary drainage together with the most suitable drainage technique selection.A multidisciplinary approach,including urologists,nephrologists,and other medical specialties,is best suited to correctly manage concomitant hemodynamic changes,fluid and electrolyte imbalances,and other related *** uropathy is one of the leading causes of *** of patients suitable for early diversion and feasibility or adequate selection of the indicated technique is sometimes challeng-ing.A thorough understanding of the physiopathology behind the development of urinary obstruction is vital for correct diagnosis and management.

关键词： Obstructive uropathy Urinary tract obstruction Obstruction of the urinary tract Acute kidney injury Urinary diversion Renal recovery

LL-37 and CsgC exemplify the crosstalk between anti-amyloid, antimicrobial, and anti-biofilm protein activities

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2023年第5期18卷 1027-1028页

作者： jaime Santos Salvador Ventura Irantzu Pallares Institut de Biotecnologia i Biomedicina Departament de Bioquímica i Biologia Molecular Universitat Autònoma de Barcelona

Protein misfolding and aggregation into amyloid fibrils is the main pathological hallmark of neurodegenerative diseases,including Alzheimer’s,Parkinson’s,Huntington’s,and prion diseases(Chiti and Dobson,2017).These insoluble fibrillar deposits possess a common structure characterized by a cross-β-sheet conformation in which β-strands run transversely to the fiber axis and form an intermolecular network of hydrogen bonds.

关键词： amyloid Huntington diseases

Nylon 6-cellulose composite hosted in a hypodermic needle: Biofluid extraction and analysis by ambient mass spectrometry in a single device

在线全文

学校读者我要写书评

暂无评论

Journal of Pharmaceutical Analysis 2023年第11期13卷 1346-1352页

作者： jaime Millan-Santiago Rafael Lucena Soledad Cardenas Affordable and Sustainable Sample Preparation(AS2P)Research Group Analytical Chemistry DepartmentChemical Institute for Energy and Environment(IQUEMA)University of CordobaE-14071CordobaSpain

This study proposes a hypodermic needle(HN)as a sorbent holder and an electrospray(ESI)emitter,thus combining extraction and analysis in a single device.A novel nylon 6-cellulose(N6-Cel)composite sorbent is proposed to extract methadone from oral fluid *** cellulosic substrate provides the composite with high porosity,permitting the flow-through of the sample,while the polyamide contributes to the extraction of the *** low price of the devices(considering the holder and the sorbent)contributes to the affordability of the method,and their small size allows easy transportation,opening the door to on-site *** the optimum conditions,the analyte can be determined by high-resolution ambient ionization mass spectrometry at a limit of detection(LOD)as low as 0.3 mg/L and precision(expressed as relative standard deviation,RSD)better than 9.3%.The trueness,expressed as relative recovery(RR),ranged from 90%to 109%.As high-resolution mass spectrometers are not available in many laboratories,the method was also adapted to low-resolution *** this sense,the direct infusion of the eluates in a triple quadrupole-mass spectrometry provided an LOD of 2.2 mg/*** RSD was better than 5.3%,and the RR ranged from 96%to 121%.

关键词： ESI emitter Mass spectrometry Hypodermic needle Composite Methadone