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Journal of Thermal Science 2024年第2期33卷 408-421页

作者： singh Shailendra ANAND Abhishek SHUKLA Amritanshu SHARMA Atul Non-Conventional Energy Laboratory Rajiv Gandhi Institute of Petroleum TechnologyJais Amethi229304India

This study evaluates the effectiveness of phase change materials(PCMs) inside a storage tank of warm water for solar water heating(SWH) system through the theoretical simulation based on the experimental model of *** et *** model is explained by five fundamental equations for the calculation of various parameters like the effectiveness of PCMs,the mass of hot water,total heat content,and duration of *** study simulated eleven PCMs to analyze their effectiveness like Sodium hydrogen phosphate dodecahydrate(SHPD),OM 37,N-Eicosane(NE),Lauric acid(LA),Paraffin wax(PW),OM 48,Paraffin wax C_(20-33)(PW-C20-33),Sodium acetate trihydrate(SAT),Palmitic acid(PA),Myristic acid(MA),and Stearic acid(SA).Among all PCMs,the SHPD has found the highest value of effectiveness factor of ***,it is the most recommended PCM for the storage tank of the SWH *** study also includes the melt fraction analysis of all enumerated PCMs corresponding to container materials of stainless steel,glass,aluminum mixed,tin,aluminum,and *** melt fraction analysis is performed by making a coding program in the FORTRAN programming *** the analysis,copper container material is found to have high melting rate for all PCMs so it is superior to other container materials.

关键词： theoretical model solar water heating system phase change material effectiveness factor melt fraction

Dual PPAR delta/gamma agonist offer therapeutic potential for Alzheimer's disease

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Neural Regeneration Research 2024年第6期19卷 1175-1176页

作者： Ian Steinke Meenakshi singh Rajesh Amin Department of Drug Discovery and Development Auburn UniversityAuburn AlabamaALUSA

The increasing incidence of Alzheimer's disease(AD)in the aging population,indicates the critical need for the development of novel targeted molecular therapies for ameliorating AD ***,clinical and preclinical evidence demonstrates that peroxisomal proliferator activating receptors(PPAR)agonists regulate energy and lipid homeostasis in models of diabetes,as well as improve spatial memory in animal models of AD(Khan et al.,2019).

关键词： Alzheimer clinical homeostasis

Nrf2 as a potential target for the treatment of epilepsy

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Neural Regeneration Research 2024年第9期19卷 1865-1866页

作者： Prince Kumar singh Tawfeeq Shekh-Ahmad Institute for Drug Research School of PharmacyFaculty of MedicineThe Hebrew University of JerusalemJerusalemIsrael

Epilepsy is a prevalent chronic brain disorder that is characterized by a persistent predisposition to recurrently generate epileptic seizures and is often associated with cognitive and psychological *** affects approximately 65 million individuals,including both males and females of all ages worldwide,and poses a significant burden on patients,their families,and the health system(Vezzani et al.,2019).

关键词： epilepsy Nrf2

Role of endoscopic ultrasound-guided biliary drainage for palliation of malignant biliary obstruction

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World Journal of Gastrointestinal Surgery 2024年第8期16卷 2369-2373页

作者： Sahib singh Saurabh Chandan Antonio Facciorusso Department of Internal Medicine Sinai HospitalBaltimoreMD 21215United States Center for Interventional Endoscopy(CIE) Advent HealthOrlandoFL 32803United States Gastroenterology Unit Department of Medical and Surgical SciencesUniversity of FoggiaFoggia 71122Italy

Endoscopic ultrasound-guided biliary drainage(EUS-BD)directs bile flow into the digestive tract and has been mostly used in patients with malignant biliary obstruction(MBO)where endoscopic retrograde cholangiopancreatography-guided biliary drainage was unsuccessful or was not *** apposing metal stents(LAMS)are deployed during EUS-BD,with the newer electrocautery-enhanced LAMS reducing procedure time and complication rates due to the inbuilt cautery at the catheter ***-BD with electrocautery-enhanced LAMS has high technical and clinical success rates for palliation of MBO,with bleeding,cholangitis,and stent occlusion being the most common adverse *** studies have even suggested comparable efficacy between EUS-BD and endosc-opic retrograde cholangiopancreatography as the primary approach for distal *** this editorial,we commented on the article by Peng et al published in the recent issue of the World Journal of Gastrointestinal Surgery in 2024.

关键词： Endoscopic ultrasound Endoscopic ultrasound guided biliary drainage Cancer Pancreas Bile duct Endoscopy

Peroxisome proliferator-activated receptor agonists:A new hope towards the management of alcoholic liver disease

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World Journal of Gastroenterology 2024年第35期30卷 3965-3971页

作者： Siva Sundara Kumar Durairajan Abhay Kumar singh Ashok Iyaswamy Department of Microbiology School of Life SciencesCentral University of Tamil NaduTiruvarur 610005India School of Biomedical Sciences Li Ka Shing Faculty of MedicineUniversity of Hong KongHong Kong 999077China School of Chinese Medicine Hong Kong Baptist UniversityHong Kong 999077China Department of Biochemistry Karpagam Academy of Higher EducationCoimbatore 641021India

In this editorial,we examine a paper by Koizumi et al,on the role of peroxisome proliferator-activated receptor(PPAR)agonists in alcoholic liver disease(ALD).The study determined whether elafibranor protected the intestinal barrier and reduced liver fibrosis in a mouse model of *** study also underlines the role of PPARs in intestinal barrier function and lipid homeostasis,which are both affected by *** therapies are necessary for ALD because it is a critical health issue that affects people *** editorial analyzes the possibility of PPAR agonists as treatments for *** key factors of inflammation and metabolism,PPARs offer multiple methods for managing the complex etiology of *** assess the abilities of PPARα,PPARγ,and PPARβ/δagonists to prevent steatosis,inflammation,and fibrosis due to liver *** research carried out in preclinical and clinical settings has shown that PPAR agonists can reduce the severity of liver *** editorial discusses the data analyzed and the obstacles,advantages,and mechanisms of action of PPAR agonists for *** research is needed to understand the efficacy,safety,and mechanisms of PPAR agonists for treating ALD.

关键词： Alcoholic liver disease Peroxisome proliferator-activated receptors Peroxisome proliferator-activated receptors agonists Liver fibrosis Inflammation Metabolic regulation Hepatoprotection

Bioresorbable stent unloading during percutaneous coronary intervention:Early detection and management

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World Journal of Cardiology 2024年第10期16卷 616-618页

作者： Nabil Eid Mohamed Abdel Wahab Amardev singh Thanu Department of Anatomy Division of Human BiologySchool of MedicineIMU UniversityKuala Lumpur 57000Kuala LumpurMalaysia Department of Pediatrics School of MedicineIMU UniversityClinical CampusBatu Paha 83000JohorMalaysia M.Kandiah Faculty of Medicine and Health Sciences University Tunku Abdul RahmanKajang 43000SelangorMalaysia

In this letter,we comment on a recent case report by Sun et al in the World Journal of *** report describes the successful management of a rare complication:The unloading or detachment of a bioresorbable stent(BRS)during percutaneous coronary intervention(PCI)in a male *** unloading of BRS was detected via angiography and intravascular ultrasound(IVUS)imaging of the left coronary artery and left anterior descending *** this case is interesting,the authors’report lacked crucial ***,insufficient information about the type of BRS used,potential causes of BRS unloading,or whether optical coherence tomography(OCT)imaging for coronary arteries was performed before,during,or after *** OCT imaging of coronary arteries before PCI can potentially prevent BRS unloading due to its higher resolution compared to *** addition,despite detecting myocardial bridging during the PCI,the authors did not provide any details regarding this *** we discuss the various types of BRS,the importance of OCT in PCI,and the clinical relevance of myocardial bridging.

关键词： Coronary artery diseases Percutaneous coronary intervention Optical coherence tomography Bioresorbable/Biodegradable stents Stent unloading/detachment Myocardial bridge Intravascular ultrasound Coronary angiography

Methyl-salicylate:A surveillance system fortriggering immunity in neighboring plants

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Journal of Integrative Plant Biology 2024年第2期66卷 163-165页

作者： Saumya Jaiswal Durgesh Kumar Tripathi Ravi Gupta JingHe Zhong-Hua Chen Vijay Pratap singh Plant Physiology Laboratory Department of Botany C.M.P.Degree CollegeA Constituent Post Graduate College ofUniversity of AllahabadPrayagraj 211002India Crop Nanobiology and Molecular Stress Physiology LabAmity Institute of Organic Agriculture Amity University UttarPradeshNoida 201313India College of General Education Kookmin UniversitySeoul 02707South Korea School of Science Western Sydney UniversitySydney 2751New South WalesAustralia Hawkesbury Institute for the Environment Western SydneyUniversitySydney 2751New South WalesAustralia

Plant behavioral actions have been one of the major topicsof research in plant biology and *** actionsfrom plants are determined by their instant structural andphysical reactions to the circumstances(Bouwmeester et al.,2019).Upon sensing abiotic factors such as salinity,flooding,high temperature,drought,plants make suitable changes intheir physiology and behavior to survive such harsh conditions.

关键词： immunity neighboring salinity

Fibrinogen’s potential role in connecting cerebrovascular abnormalities with glymphatic dysfunction in Alzheimer’s disease

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Neural Regeneration Research 2025年第1期20卷 203-204页

作者： Vishal singh Arnab Choudhury Hyung Jin Ahn Department of Pharmacology Physiology and NeurosciencesRutgers-New Jersey Medical SchoolNewarkNJUSA Brain Health Institute Rutgers UniversityPiscatawayNJUSA

Alzheimer’s disease(AD)stands out as the primary manifestation of age-related dementia,portraying a chronic neurodegenerative disorder distinguished by the accumulation of fibrillar amyloid-β(Aβ)plaques and neurofibrillary tangles of hyperphosphorylated ***,from a clinical standpoint,AD presents itself as a complex condition with a spectrum of dysfunctions rather than a singular pathological *** often-overlooked aspect of the disease is the presence of extensive cerebrovascular abnormalities,given that the majority of AD patients experience altered cerebral blood flow,damaged vasculature,increased microinfarcts and *** models of AD further support this observation,showing cerebrovascular dysfunction such as impaired cerebral blood flow and altered cerebrovascular reactivity(Tataryn et al.,2021;Gareau et al.,2023).

关键词： cerebrovascular dysfunction Alzheimer

Hybrid silver nanoparticles:Modes of synthesis and various biomedical applications

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Electron 2024年第2期2卷 196-218页

作者： Priyanka singh Shivang singh Balaji Maddiboyina SaiKrishna Kandalam Tomasz Walski Raghvendra A.Bohara Centre for Interdisciplinary Research D.Y.Patil Educational SocietyKolhapurIndia Department of Internal Medicine Rauta Hospital Pvt.LtdGaighatUdayapurNepal Department of Medical and Scientific Communications Scientific Writing ServicesFreyr Global Regulatory Solutions&ServicesHyderabadTelanganaIndia INSERM U 1066 ‘Micro et Nanomédecines Biomimétiques-MINT’AngersFrance UniversitéAngers UMR-S1066AngersFrance Department of Biomedical Engineering Wroclaw University of Science and TechnologyWroclawPoland University of Galway

In the present day,there is a growing trend of employing new strategies to synthesize hybrid nanoparticles,which involve combining various functionalities into a single nanocomposite *** modern methods differ significantly from the traditional classical approaches and have emerged at the forefront of materials *** fabrication of hybrid nanomaterials presents an unparalleled opportunity for applica-tions in a wide range of areas,including therapy to *** focus of this review article is to shed light on the different modalities of hybrid nanoparticles,providing a concise description of hybrid silver nano-particles,exploring various modes of synthesis and classification of hybrid silver nanoparticles,and highlighting their ***-tionally,we discussed core-shell silver nanoparticles and various types of core and shell combinations based on the material category,such as dielectric,metal,or *** two primary classes of hybrid silver nanoparticles were also ***,various hybrid nanoparticles and their methods of synthesis were discussed but we emphasize silica as a suitable candidate for hybridization alongside metal *** choice is due to its hydrophilic surface qualities and high surface charge,which provide the desired repulsive forces to minimize aggregation between the metal nanoparticles in the liquid *** shell encapsulation also provides chemical inertness,robustness and the adaptability to the desired hybrid ***,among all the materials used to coat metal nanoparticles;silica is highly approved.

关键词： biomedical applications hybrid silver nanoparticles polyvinylpyrrolidone silica shell surface enhanced Raman spectroscopy

Anaplastic thyroid cancer: Unveiling advances in diagnosis andmanagement

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World Journal of Clinical Oncology 2024年第7期15卷 786-789页

作者： Treshita Dey Budhi singh Yadav Department of Radiotherapy&Oncology Post-Graduate Institute of Medical Education&ResearchChandigarh 160012India

The review article by Pavlidis et al published in World J Clin Oncol provides a meticulous analysis of the intricacies surrounding anaplastic carcinoma of the *** carcinoma encompasses a spectrum of diseases,each charac-terized by distinct behaviors and *** approaches encompass a diverse array of *** remains the pivotal treatment for anaplastic thyroid *** and chemotherapy offer the best overall sur-vival in aggressive *** of immunotherapy with targeted the-rapies,such as dabrafenib-trametinib,demonstrate potential for enhanced effect-iveness and improved survival *** approach fuelled by precision medicine and interdisciplinary collaboration is imperative in charting a course toward improved outcomes in this formidable malignancy.

关键词： Anaplastic thyroid cancer Surgery Radiotherapy Chemotherapy Targeted therapy Immunotherapy