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Prognostic analysis and comparison of colon cancer in Han and Hui patients

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World Journal of Gastroenterology 2014年第17期20卷 5082-5086页

作者： Mei Zhang Qu-Chuan Zhao Yan-Peng Liu Lei Yang Hong-Ming Zhu Jagadish K Chhetri Department of Gastroenterology Xuanwu HospitalCapital Medical University

AIM:To investigate the relevant prognostic factors and their differences between colorectal cancer(CRC)patients of Chinese Han and Hui ethnicities in the Beijing region.METHODS:A retrospective analysis of 880 patients diagnosed with CRC at Xuanwu Hospital,Capital Medical University between September 2001 and September2011 was performed.Among the 880 patients,398 and482 were Hui and Han,respectively.Characteristics including sex,age,diet,tumor size,primary tumor site,Dukes’stage and degree of differentiation were analyzed for their influence on prognosis.Data on dietary structures were recorded through a questionnaire survey conducted during the patient’s first visit,return visit or follow-up checkups.RESULTS:Among patients with colon cancer,the5-year survival rate for patients of Hui ethnicity was lower than that for Han patients(P=0.025).Six risk factors(age of onset,dietary structure,tumor size,Dukes’stage,location of cancer and degree of differentiation)in both Han and Hui patients were identified as prognostic factors(Pkes’stage(P=0.000)and degree of differentiation(P=0.000)are prognostic factors affecting both ethnic groups.Comparison of prognostic factors between Han and Hui patients with CRC showed that dietary structure was a statistically significant factor,and diet varied significantly between the two ethnic groups.CONCLUSION:Dietary structure has a significant influence on colon cancer prognosis among Han and Hui patients with colon cancer in Beijing,which may cause a difference in their survival rates.

关键词： Colon cancer Colorectal cancer Han patients Hui pa

Process control factors for continuous microbial perchlorate reduction in the presence of zero-valent iron

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Frontiers of Environmental Science & Engineering 2014年第3期8卷 386-393页

作者： Robert D. ARTHUR jagadish TORLAPATI kyung-Hee SHIN Daniel k. CHA Yeomin YOON Ahjeong SON Department of Civil Engineering Auburn University Auburn AL 36849 USA korea Environment Institute Seoul 122-706 Republic of Korea Department of Civil and Environmental Engineering University of Delaware Newark DE 19716 USA Department of Civil and Environmental Engineering University of South Carolina Columbia SC 29208 USA Department of Environmental Science and Engineering Ewha Womans University Seoul 120-750 Korea

Process control parameters influencing microbial perchlorate reduction via a flow-through zero-valent iron （ZVI） column reactor were investigated in order to optimize perchlorate removal from water. Mixed perchlorate reducers were obtained from a wastewater treatment plant and inoculated into the reactor without further acclimation. Examined parameters included hydraulic residence time （HRT）, pH, nutrients requirement, and perchlorate reduction kinetics. The minimum HRT for the system was concluded to be 8 hr. The removal efficiency of 10 mg. L-1 influent perchlorate concentration was reduced by 20%-80% without control to the neutral pH （HRT = 8 hr）. Therefore pH was determined to be an important parameter for microbial perchlorate reduction. Furthermore, a viable alternative to pH buffer was discussed. The microbial perchlorate reduction followed the first order kinetics, with a rate constant （k） of 0.761 hr-1. The results from this study will contribute to the implementation of a safe, cost effective, and efficient system for perchlorate reduction to below regulated levels.

关键词： perchlorate zero-valent iron （ZVI） microbial reduction hydrogen

High day and night temperatures impact on cotton yield and quality——current status and future research direction

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棉花研究(英文) 2023年第3期6卷 209-225页

作者： SAINI Dinesh k. IMPA S.M. MCCALLISTER Donna PATIL Gunvant B. ABIDI Noureddine RITCHIE Glen JACONIS S.Y. jagadish krishna S.V. Department of Plant and Soil Science Texas Tech UniversityLubbockTX 79410USA Department of Agricultural and Applied Economics Texas Tech UniversityLubbockTX 79410USA Institute of Genomics for Crop Abiotic Stress Tolerance Texas Tech UniversityLubbockTX 79410USA Fiber and Biopolymer Research Institute Texas Tech UniversityLubbockTX 79410USA Cotton Incorporated CaryNC 27513USA

Heat waves,and an increased number of warm days and nights,have become more prevalent in major agricultural regions of the world.Although well adapted to semi-arid regions,cotton is vulnerable to high temperatures,particularly during flowering and boll development.To maintain lint yield potential without compromising its quality under high-temperature stress,it is essential to understand the effects of heat stress on various stages of plant growth and development,and associated tolerance mechanisms.Despite ongoing efforts to gather data on the effects of heat stress on cotton growth and development,there remains a critical gap in understanding the distinct influence of high temperatures during the day and night on cotton yield and quality.Also,identifying mechanisms and target traits that induce greater high day and night temperature tolerance is essential for breeding climate-resilient cotton for future uncertain climates.To bridge these knowledge gaps,we embarked on a rigorous and comprehensive review of published literature,delving into the impact of heat stress on cotton yields and the consequential losses in fiber quality.This review encompasses information on the effects of heat stress on growth,physiological,and biochemical responses,fertilization,cotton yield,and quality.Additionally,we discuss management options for minimizing heat stress-induced damage,and the benefits of integrating conventional and genomics-assisted breeding for developing heat-tolerant cotton cultivars.Finally,future research areas that need to be addressed to develop heat-resilient cotton are proposed.

关键词： Controlled environment Cotton Fiber yield and quality Heat stress Heat tents Reproductive failure

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促进竹房屋系统及近期发展(英文)

世界竹藤通讯 2006年第2期4卷 5-10页

作者： Shri k.Shyamasundar jagadish Vengala Indian Plywood Industries Research & Training Institute

竹房屋系统的建造与实用建筑的方法有很大的区别。(1)原竹的利用和构架椽子作为主要的承载元素;(2)劈蔑竹和竹片胶合作为剪切壁,它能起到透风的作用,并能为其结构提供整体的稳定性;(3)根据危害和公共条件的程度作适当的竹子防腐处理;(4... 详细信息

竹房屋系统的建造与实用建筑的方法有很大的区别。(1)原竹的利用和构架椽子作为主要的承载元素;(2)劈蔑竹和竹片胶合作为剪切壁,它能起到透风的作用,并能为其结构提供整体的稳定性;(3)根据危害和公共条件的程度作适当的竹子防腐处理;(4)在屋顶结构上,用于承载的接合点与软钢螺丝相结用于竹子的三角架;(5)竹席皱纹片用于顶部的包层。根据房屋的设计、内部的修饰和当地的条件,建造房屋时可采用低成本,在印度,每张板的价格为300￣500 卢比/m2。为了改进技术,印度胶合板工业研究与培训所近几年修建了几个样板建筑。活动房的具体建筑、创新理念以及观点在本文进行了阐述。

关键词：竹房屋系统防腐处理实用建筑低成本屋顶结构

Hetero-interfacial nickel nitride/vanadium oxynitride porous nanosheets as trifunctional electrodes for HER,OER and sodium ion batteries

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能源化学:英文版 2023年第6期81卷 71-81,I0003页

作者： Tuzhi Xiong Jingting Li jagadish Chandra Roy Malcolm koroma Zhixiao Zhu Hao Yang Lei Zhang Ting Ouyang M.-Sadeeq Balogun Mohammad Al-Mamun College of Materials Science and Engineering Hunan Joint International Laboratory of Advanced Materials and Technology for Clean EnergyHunan UniversityChangsha 410082HunanChina Centre for Catalysis and Clean Energy Griffith UniversityGold Coast CampusSouthportQLD 4222Australia College of Mechanical and Vehicle Engineering Hunan UniversityChangsha 410082HunanChina Guangxi key Laboratory of Electrochemical Energy Materials School of Chemistry&Chemical EngineeringGuangxi UniversityNanning 530004GuangxiChina Guangxi key Laboratory of Information Materials Guilin University of Electronic TechnologyGuilin 541004GuangxiChina

The development of single electrode with multifunctional purposes for electrochemical devices remains a symbolic challenge in recent technology.This work explores interfacially-rich transition metal nitride hybrid that consist of nickel nitride and vanadium oxynitride(VO_(0.26)N_(0.52))on robust carbon fiber(denoted CF/Ni_(3)N/VON)as trifunctional electrode for hydrogen evolution reaction(HER),oxygen evolution reaction(OER),and sodium ion batteries(SIBs).The as-prepared CF/Ni_(3)N/VON exhibits low HER overpotential of 48 m V@10 m A cm^(-2),OER overpotential of 287 m V@10 m A cm^(-2),and sodium-ion anode storage reversible capacity of 555 m A h g^(-1)@0.2 C.Theoretical analyses reveal that the Ni_(3)N effectively facilitates hydrogen desorption for HER,increases the electrical conductivity for OER,and promotes the Na-ion storage intercalation process,while the VON substantially elevates the water dissociation kinetics for HER,accelerates the adsorption of OH*intermediate for OER and enhances the Na-ion surface adsorption storage process.Owing to the excellent HER and OER performances of the CF/Ni_(3)N/VON electrode,an overall water splitting device denoted as CF/Ni_(3)N/VON//CF/Ni_(3)N/VON was not only assembled showing an operating voltage of 1.63 V at current density of 10 m A cm^(-2)but was also successfully self-powered by the assembled CF/Ni_(3)N/VON//CF/Na_(3)V_(2)(PO_(4))_(3) flexible sodium ion battery.This work will contribute to the development of efficient and cost-effective flexible integrated electrochemical energy devices.

关键词： Interstitial nitride Trifunctional electrode Heterointerface Alkaline water splitting Sodium ion battery

Gene expression profile of esophageal cancer in North East India by cDNA microarray analysis

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World Journal of Gastroenterology 2007年第9期13卷 1438-1444页

作者： Indranil Chattopadhyay Sujala kapur Joydeep Purkayastha Rupkumar Phukan Amal kataki jagadish Mahanta Sunita Saxena Institute of Pathology Indian Council of Medical ResearchSafdarjang Hospital Campus Post Box No. 4909 New Delhi 110029 India B.Borooah Cancer Institute Guwahati-781016 Assam IndiaDr. Regional Medical Research Center Dibrugarh-786001 Assam India

AIM: To identify alterations in genes and molecular functional pathways in esophageal cancer in a high incidence region of India where there is a widespread use of tobacco and betel quid with fermented areca nuts. METHODS: Total RNA was isolated from tumor and matched normal tissue of 16 patients with esophageal squamous cell carcinoma. Pooled tumor tissue RNA was labeled with Cy3-dUTP and pooled normal tissue RNA was labeled with Cy5-dUTP by direct labeling method. The labeled probes were hybridized with human 10k cDNA chip and expression profiles were analyzed by Genespring GX V 7.3 (Silicon Genetics). RESULTS: Nine hundred twenty three genes were differentially expressed. Of these, 611 genes were upregulated and 312 genes were downregulated. Using stringent criteria (P ≤ 0.05 and ≥ 1.5 fold change), 127 differentially expressed genes (87 upregulated and 40 downregulated) were identified in tumor tissue. On the basis of Gene Ontology, four different molecular functional pathways (MAPk pathway, G-protein coupled receptor family, ion transport activity, and serine or threonine kinase activity) were most significantly upregulated and six different molecular functional pathways (structural constituent of ribosome, endopeptidase inhibitor activity, structural constituent of cytoskeleton, antioxidant activity, acyl group transferase activity, eukaryotic translation elongation factor activity) were most significantly downregulated. CONCLUSION: Several genes that showed alterations in our study have also been reported from a high incidence area of esophageal cancer in China. This indicates that molecular profiles of esophageal cancer in these two different geographic locations are highly consistent.

关键词：印度东北部地区食管癌基因表达 cDNA微阵列分析

Exploring the impact of soil water variability and varietal diversity on alfalfa yield,nutritional quality,and farm profitability

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Grassland Research 2023年第4期2卷 266-278页

作者： Rudra Baral S.V.krishna jagadish Nathan Hein Romulo P.Lollato Aleksan Shanoyan Anil k.Giri Jiyung kim Myungkyo kim Doohong Min University of Missouri Extension ColumbiaMissouriUSA Deartment of Plant and Soil Science Texas Tech UniversityLubbockTexasUSA Department of Agronomy Kansas State UniversityManhattanKansasUSA Department of Agricultural Economics Kansas State UniversityManhattanKansasUSA Economic Research Service United States Department of AgricultureKansas CityMissouriUSA School of Business Hanyang UniversitySeoulSouth Korea

Background:Despite high nutritional and economic value,alfalfa yield has not been improved in the United States.Soil moisture critically influences alfalfa's yield and quality,affecting its physiological processes,nutrient uptake,and stand growth.Additionally,the maturity stage at harvest can significantly impact both hay yield and quality.Thus,this study aimed to assess the effect of different soil moisture levels and harvesting times on forage yield,nutritive value,and the overall profitability of commercially cultivated alfalfa.Methods:Two conventional and three lower-lignin alfalfa varieties were planted in a randomized complete block with split plot design under drought,rainfed,and irrigation conditions in 2020 in Manhattan,kansas,USA.The dry matter yield(DMY)and forage nutritive value were evaluated at late bud,early flowering,and 7 days after early flowering stages,respectively.Results:DMY varied with production year,soil water availability,and growth stages,with drought conditions causing a decline in DMY of 5%to 38%in the second production year.Water conditions and maturity stages influenced crude protein(CP)and in vitro dry matter digestibility(IVDMD).Higher soil moisture and advancing maturity stages negatively impacted CP,IVDMD,and relative forage quality.The study revealed net profit margins of 62%,64%,and 52%for drought-prone,rainfed,and irrigated production,respectively.Conclusions:Harvest timing and irrigation practices were found to have substantial implications for forage yield and nutritive value of alfalfa.The yield-quality trade-off differed under drought and irrigation,with early harvesting leading to lower yields but higher protein content and digestibility.The study findings provide potential guidance for improving alfalfa hay yield,quality,and profitability.

关键词： crude protein drought dry matter yield forage nutritive value irrigation net farm income rainfed relative forage quality

Standardization of the Meter Protocol

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通讯和计算机（中英文版） 2011年第4期8卷 307-312页

作者： k. jagadish Rao k.L. Puttabuddhi Department of ECE VTU University BTL Institute of Technology Bangalore 560069 India Department of Electrical Engineering SJ College of Engineering VTU University Mysore 570006 India

野生型和Msp1突变体水稻减数分裂期转录水平上的基因表达分析(英文)

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西北农林科技大学学报（自然科学版） 2009年第11期37卷 69-78页

作者：周维赵继新楼辰军 krishna jagadish 周雷 John Bennett 李自超中国农业大学农业部作物基因组学与遗传改良重点实验室/北京市作物遗传改良实验室北京100193 国际水稻研究所(IRRI) 分子生物学实验室天津农业科学院农作物研究所天津300112 西北农林科技大学农学院陕西杨凌712100

【目的】深入探索水稻减数分裂期间配子体发育的分子机理,大规模发掘与水稻配子体发育相关的基因,以便更有把握地利用基因工程手段改造水稻配子体发育的进程。【方法】利用22kAilentcDNA芯片,在全基因组水平上对野生型水稻和Msp1突变体... 详细信息

【目的】深入探索水稻减数分裂期间配子体发育的分子机理,大规模发掘与水稻配子体发育相关的基因,以便更有把握地利用基因工程手段改造水稻配子体发育的进程。【方法】利用22kAilentcDNA芯片,在全基因组水平上对野生型水稻和Msp1突变体在减数分裂期间表达基因的表达情况进行研究和分析。【结果】有208个基因在野生型和Msp1突变体中的表达差异极显著(P≤0.01,lgRatio≥0.2);对这些基因的核酸序列进行分析、GO(GeneOntology)注释以及功能预测后,将其划归为18个大类,分别涉及到GTP、DNABinding、细胞壁、激酶活性、叶绿体、减数分裂、胚珠、染色体、花粉囊、内膜、细胞分裂、泛素、转运、代谢、蛋白解、Ca2+结合、RNA结合、以及未知功能等;统计分析表明,有99个基因与染色体有关,占总数的47.60%;39个基因与内膜系统有关,占总数的18.75%;有1个基因与减数分裂紧密相关,3个基因与Ca2+结合过程有关;另外有3个基因在Msp1突变体中的表达极显著高于野生型,表明这3个基因很可能参与了绒粘层的发育调控。基因芯片和RT-PCR检测结果表明,水稻基因Ak070642特异于绒粘层,说明其参与了绒粘层的发育调控。【结论】研究通过基因芯片技术,将野生型水稻与其Msp1突变体在减数分裂期间表达基因的表达情况进行大规模对比后发现,有208个基因分别从细胞代谢、绒毡层的发育、离子转运、核酸代谢、激酶活性等方面调控水稻的减数分裂过程,为深入理解水稻减数分裂和配子体发育的分子机理提供了实验支撑。

关键词：水稻 cDNA基因芯片 Msp1突变体野生型减数分裂配子体发育