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Non-Newtonian Flow of Blood in a Catheterized Bifurcated Stenosed Artery

Journal of Bionic Engineering 2018年第1期15卷 173-184页

作者： jagadis chandra misrat Gopal chandra Shit Ranjan Pramanik Centre for Healtheare Science and Technology Indian Institute of Engineering Science and Technology Shibpur 711103 lndia Department of Mathematics Jadavpur University Kolkata 700032 India Department of Mathematics Indian Institute of Technology Kharagpur 721302 lndia

The paper is devoted to study the non-Newtonian behavior of blood flowing in an artery having a stenosis, in a situation when a catheter has been inserted into it. The blood rheology is described by Herschel-Bulkley fluid model. The flow configuration is con- structed by choosing suitable curvature at the lateral junction, where the flow separation is initiated. The effects of insertion of catheter and that of yield stress of blood on the velocity distribution, rate of flow and flow resistance of blood, distribution of shear stress at the arterial wall and the location of yield plane are investigated. The results provide some useful information for the prediction/treatment of some arterial diseases and circulatory disorders of the cardiovascular system, in a situation, when a stenosis is developed on the endothelium of the daughter artery / bifurcated artery. The study reveals that if the ratio between the radii of the catheter and the artery is increased, the shear stress at the arterial wall diminishes. However, when the bifurcation angle is increased, the wall shear stress is enhanced.

关键词： Herschel-Bulkley fluid model arterial bifurcation catheterized artery yield plane flow resistance

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Nitric oxide regulation of plant metabolism

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Molecular Plant 2022年第2期15卷 228-242页

作者： Kapuganti jagadis Gupta Vemula chandra Kaladhar Teresa B.Fitzpatrick Alisdair R.Fernie Ian Max Møller Gary J.Loake National Institute of Plant Genome Research Aruna Asaf Ali MargNew DelhiDelhi 110067 India Vitamins and Environmental Stress Responses in Plants Department of Botany and Plant BiologyUniversity of GenevaGeneva 1211 Switzerland Max-Planck-Institute of Molecular Plant Physiology Am Mühlenberg 1Potsdam-Golm 14476 Germany Department of Molecular Biology and Genetics Aarhus UniversityForsøgsvej 14200 SlagelseDenmark Institute of Molecular Plant Sciences School of Biological SciencesUniversity of EdinburghEdinburgh EH93BFUK

Nitric oxide(NO)has emerged as an important signal molecule in plants,having myriad roles in plant *** addition,NO also orchestrates both biotic and abiotic stress responses,during which intensive cellular metabolic reprogramming *** to these responses is the location of NO biosynthetic and scavenging pathways in diverse cellular compartments,enabling plants to effectively organize signal transduction *** regulates plant metabolism and,in turn,metabolic pathways reciprocally regu-late NO accumulation and ***,these diverse cellular processes are inextricably *** re-view addresses the numerous redox pathways,located in the various subcellular compartments that pro-duce NO,in addition to the mechanisms underpinning NO *** focus on how this molecular dance is integrated into the metabolic state of the *** this context,a reciprocal relationship be-tween NO accumulation and metabolite production is often *** also showcase cellular pathways,including those associated with nitrate reduction,that provide evidence for this integration of NO function and ***,we discuss the potential importance of the biochemical reactions governing NO levels in determining plant responses to a changing environment.

关键词： hypoxi amitochondria metabolism nitric oxide S-nitrosylation pyridoxine reactive nitrogen species reactive oxygen species

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