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Manageme.t.of obstructed colore.t.l carcinoma in an emergency se.t.ng:An update

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World Journal of Gastrointe.t.nal Oncology 2024年第3期16卷 598-613页

作者： efstathios t Pavlidis Ioannis N Galanis theodoros e Pavlidis 2nd Propede.t.c Departme.t.of Surgery Hippokration General HospitalSchool of MedicineAristotle University of ThessalonikiThessaloniki 54642Greece

Colore.t.l carcinoma is common,particularly on the le.t.*** 20%of patie.t.,obstruction and ileus may be.t.e first clinical manife.t.tions of a carcinoma that has advanced(stage II,III or even IV).Diagnosis is based on clinical prese.t.tion,plain abdominal radiogram,computed tomography(Ct),Ct colonography and positron emission tomography/*** be.t.manageme.t.strategy in terms of short-term operative or interve.t.onal and long-term oncological outcomes re-mains *** the most common le.t.sided obstruction,the first choice should be e.t.er emergency surgery or endoscopic decompression by self-expen-dable metal ste.t. or *** operative plan should be e.t.er one-stage or two-stage ***-stage rese.t.on with on-table bowel decompression and irrigation can be accompanied or not accompanied by proximal defunctioning stoma(colostomy or ileostomy).Primary anastomosis is more convenie.t.but has increased risks of anastomotic leakage and ***-stage rese.t.on(Hart-mann’s procedure)is safer and the most widely used despite.t.mporally affe.t.ng quality of *** control surgery in high-risk frail patie.t. is less freque.t.y performed since it can be successfully substituted with endoscopic ste.t.ng or *** the less common right-sided obstruction,one-stage surgical rese.t.on is more beneficial than endoscopic *** role of minimally invasive surgery(laparoscopic or robotic)is a subje.t.of *** laparoscopic-assisted manageme.t.is advantageous to some e.t.nt but requires much expe.t.se due.t. inhere.t.difficulties in disse.t.ng the distended colon and the risk of rup-ture and subseque.t.se.t.c *** decompressing ste.t.as a bridge.t. ele.t.ve surgery more substantially decreases the risks of morbidity and mortality than emergency surgery for decompression and has equivale.t.medium-term overall survival and disease-free survival *** combination with neoadjuvant chemotherapy or radiation may have a p

关键词： Acute abdomen Obstructive ileus Colore.t.l carcinoma emergency surgery Cole.t.my Intraluminal metal ste.t.

New trends in diagnosis and manageme.t.of gallbladder carcinoma

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World Journal of Gastrointe.t.nal Oncology 2024年第1期16卷 13-29页

作者： efstathios t Pavlidis Ioannis N Galanis theodoros e Pavlidis ^(nd)Propede.t.c Departme.t.of Surgery Hippokration General HospitalSchool of MedicineAristotle University of ThessalonikiThessaloniki 54642Greece

Gallbladder(GB)carcinoma,although relatively rare,is the most common biliary tree cholangiocarcinoma with aggressiveness and poor *** is closely associated with cholelithiasis and long-standing large(>3 cm)gallstones in up to 90%of *** other main predisposing factors for GB carcinoma include molecular factors such as mutated genes,GB wall calcification(porcelain)or mainly mucosal microcalcifications,and GB polyps≥1 cm in *** is made by ultrasound,computed tomography(Ct),and,more precisely,magnetic resonance imaging(MRI).Preoperative staging is of gre.t.importance in decisionmaking regarding therape.t.c *** staging is based on MRI findings,the leading technique for liver metastasis imaging,enhanced three-phase Ct angiography,or magnetic resonance angiography for major vessel *** is also necessary to use positron emission tomography(Pet)-Ct or ^(18)F-FDG Pet-MRI to more accurately dete.t.metastases and any other occult deposits with active metabolic *** laparoscopy may dete.t.dissemination not otherwise found in 20%-28.6%of *** tre.t.e.t.is needed,including surgical rese.t.on,targeted therapy by biological age.t. according to molecular te.t.ng gene mapping,chemotherapy,radiation therapy,and *** is of gre.t.importance.t. understand the updated guidelines and curre.t.tre.t.e.t.*** e.t.nt of surgical interve.t.on depends on the disease stage,ranging from simple cholecyste.t.my(t1a)to e.t.nded rese.t.ons and including e.t.nded cholecyste.t.my(t1b),with wide lymph node rese.t.on in every case or IV-V segme.t.ctomy(t2),hepatic trisegme.t.ctomy or major hepate.t.my accompanied by hepaticojejunostomy Roux-Y,and adjace.t.organ rese.t.on if necessary(t3).Laparoscopic or robotic surgery shows fewer postoperative complications and equivale.t.oncological outcomes when compared to open surgery,but much atte.t.on must be paid to avoiding *** addition to surgery,novel targe

关键词： Biliary tract neoplasms e.t.ahepatic cholangiocarcinoma Gallbladder carcinoma Gallbladder diseases Biliary tree diseases Gastrointe.t.nal malignancies

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伊桑的自行车之行

中学生英语 2024年第5期 22-23页

作者： RV Staff Writer e.t. 高齐云(选译) 不详

伊森坐在他的自行车上,骑得很快。在骑到车道的尽头时,他转过弯把自行车停在妈妈面前。“看到了吗?我再也不会摔倒了。我现在可以自己骑车去公园了吗?”他以前骑自行车去过公园,但妈妈或爸爸总是陪他一起。他确信自己能独立完成这件事... 详细信息

伊森坐在他的自行车上,骑得很快。在骑到车道的尽头时,他转过弯把自行车停在妈妈面前。“看到了吗?我再也不会摔倒了。我现在可以自己骑车去公园了吗?”他以前骑自行车去过公园,但妈妈或爸爸总是陪他一起。他确信自己能独立完成这件事。妈妈看着伊森。“你的头盔戴紧了吗?”她问,“戴紧了!”他说。“好的。”

关键词：自行车伊森公园妈妈

Ag-integrated mixed metallic Co-Fe-Ni-Mn hydroxide composite as advanced ele.t.ode for high-performance hybrid supercapacitors

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Journal of energy Chemistry 2024年第1期88卷 579-591,I0013页

作者： Anki Reddy Mule Bhimanaboina Ramulu Shaik Junied Arbaz Anand Kurakula jae Su Yu Departme.t.of ele.t.onics and Information Convergence engineering Institute for Wearable Convergence ElectronicsKyung Hee UniversityYongin-siGyeonggi-do 17104Republic of Korea

Dire.t.growth of redox-active noble metals and rational design of multifunctional ele.t.ochemical active materials play crucial roles in developing novel ele.t.ode materials for energy storage *** this regard,silver(Ag)has attracted gre.t.atte.t.on in the design of efficie.t.*** by the house/building process,which means ele.t.ng the right land,it lays a strong foundation and building esse.t.al columns for a complex ***,we report the construction of multifaceted heterostructure cobalt-iron hydroxide(CFOH)nanowires(NWs)@nickel cobalt manganese hydroxides and/or hydrate(NCMOH)nanoshe.t.(NSs)on the Ag-deposited nickel foam and carbon cloth(i.e.,Ag/NF and Ag/CC)***,the formation and charge storage mechanism of Ag are described,and these contribute.t. good conductive and redox chemistry *** switching archite.t.ral integrity of metal and redox materials on metallic frames may significantly boost charge storage and rate performance with noticeable drop in *** as-fabricated Ag@CFOH@NCMOH/NF ele.t.ode delivered superior areal capacity value of 2081.9μA h cm^(-2)at 5 mA cm^(-2).Moreover,as-assembled hybrid cell based on NF(HC/NF)device exhibited remarkable areal capacity value of 1.82 mA h cm^(-2)at 5 mA cm^(-2)with excelle.t.rate capability of 74.77%even at 70 mA cm^(-2)Furthermore,HC/NF device achieved maximum energy and power densities of 1.39 mW h cm^(-2)and 42.35 mW cm^(-2),*** verify practical applicability,both devices were also te.t.d to serve as a self-charging station for various portable ele.t.onic devices.

关键词： Curre.t.colle.t.rs Redox-active silver transition metal-hydroxides ele.t.ochemical performance Hybrid supercapacitor

Curre.t.considerations on intraductal papillary neoplasms of the bile duct and pancre.t.c duct

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World Journal of Gastroe.t.rology 2024年第10期30卷 1461-1465页

作者： efstathios t Pavlidis Ioannis N Galanis theodoros e Pavlidis 2^(nd) Propede.t.c Departme.t.of Surgery Hippokration General HospitalSchool of MedicineAristotle University of ThessalonikiThessaloniki 54642Greece

Pancre.t.biliary intraductal papillary neoplasms(IPNs)represe.t.precursors of pancre.t.c cancer or bile duct cholangiocarcinoma that can be dete.t.d and *** advances in diagnostic methods,ide.t.fying these premalignant lesions is still challenging for tre.t.e.t.*** imaging,biomarkers and molecular te.t. for genomic alterations can be used for diagnosis and *** interve.t.on in combination with new chemotherape.t.c age.t. is considered the optimal tre.t.e.t.for malignant *** balance between the risk of malignancy and any risk of rese.t.on guides manageme.t.policy;therefore.t.e.t.e.t.should be individualized based on a meticulous preoperative assessme.t.of high-risk *** of the bile duct is more aggressive.t.us,early diagnosis and surgery are *** conservative manageme.t.of low-risk pancre.t.c branch-duct lesions is safe and effe.t.ve.

关键词： Biliary tree diseases Pancre.t.c cystic neoplasms Biliary tract neoplasms e.t.ahepatic cholangiocarcinoma Pancre.t.c adenocarcinoma

Strong coupling and catenary field enhanceme.t.in the hybrid plasmonic metamaterial cavity and tMDC monolayers

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Opto-ele.t.onic Advances 2024年第5期7卷 20-32页

作者： Andergachew Mekonnen Berhe Khalil As’ham Ibrahim Al-Ani Haroldo t.Hattori Andrey e.Miroshnichenko School of engineering and technology University of New South Wales at CanberraNorthcott DriveCanberra ACT 2610Australia

Strong coupling between resonantly matched surface plasmons of metals and excitons of quantum emitters results in the formation of new plasmon-exciton hybridized energy *** plasmon-exciton strong coupling,plasmonic nanocavities play a significant role due.t. their ability to confine light in an ultrasmall ***,two-dimensional transition metal dichalcogenides(tMDCs) have a significant exciton binding energy and remain stable at ambie.t.conditions,making them an excelle.t.alternative for inve.t.gating light-matter *** a result,strong plasmon-exciton coupling has been reported by introducing a single metallic ***,single nanoparticles have lower spatial confineme.t.of ele.t.omagnetic fields and limited tunability to match the excitonic ***,we introduce.t.e conce.t.of catenary-shaped optical fields induced by plasmonic metamaterial cavities to scale.t.e strength of plasmon-exciton *** demonstrated plasmon modes of metallic metamaterial cavities offer high confineme.t.and tunability and can match with the excitons of tMDCs to exhibit a strong coupling regime by tuning e.t.er the size of the cavity gap or *** calculated Rabi splitting of Au-MoSe_2 and Au-WSe_2 heterostructures strongly depends on the catenary-like field enhanceme.t.induced by the Au cavity,resulting in room-temperature Rabi splitting ranging between 77.86 and 320 me *** plasmonic metamaterial cavities can pave.t.e way for manipulating excitons in tMDCs and operating active nanophotonic devices at ambie.t.temperature.

关键词： catenary-shaped field enhancement strong coupling plasmon exciton Rabi splitting

Curre.t.considerations for the surgical manageme.t.of gallbladder adenomas

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World Journal of Gastrointe.t.nal Surgery 2024年第6期16卷 1507-1512页

作者： efstathios t Pavlidis Ioannis N Galanis theodoros e Pavlidis the Second Departme.t.of Propaede.t.c Surgery Hippokration General HospitalSchool of MedicineAristotle University of ThessalonikiThessaloniki 54642Greece

Gallbladder adenomas are rare lesions(0.5%)associated with pote.t.al malignant transformation,particularly with gallbladder adenomas that are≥1 cm in *** dete.t.on and manageme.t.are crucial for preve.t.ng lethal carcinoma *** polyps can often be distinguished from the more often nonneo-plastic chole.t.rol pseudopolyps(5%-10%),which are *** is the first-line.t.ol for initial diagnosis and follow-up when *** que.t.on is whether cholecyste.t.my is always necessary for all *** manage-me.t.of gallbladder adenomas is determined according to the size of the.t.mor,the growth rate of the.t.mor,the patie.t.s symptoms and whether risk factors for malignancy are ***≥1 cm in size,an age>50 years and a familial history of gallbladder carcinoma are indications for immediate laparoscopic ***,ultrasound follow-up is *** adenomas 6-9 mm in size.t.e absence of≥2 mm growth at 6 months,one year,and two years,as well as an adenoma sizedthout existing risk factors indicates that no further surveillance is ***,it would be preferable.t. individualize.t.e manageme.t.in doubtful *** interve.t.onal modalities for preserving the gallbladder need further evaluation,especially to determine.t.e long-term outcomes.

关键词： Biliary diseases true neoplastic polyps Gallbladder adenomas Benign bi-liary tumors Gallbladder polyps e.t.ahepatic biliary neoplasms

Facile synthesis of intra-nanogap enhanced Raman tags with differe.t.shapes

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Nano Research 2024年第9期17卷 8415-8423页

作者： Sanjun Fan Brian t.Scarpitti Zhewen Luo Abigail e.Smith Jian Ye Zachary D.Schultz Departme.t.of Chemistry and Biochemistry The Ohio State UniversityColumbusOhio 43210USA School of Biomedical engineering Shanghai Jiao Tong UniversityShanghai 200030China

Hot spot engineering in plasmonic nanostructures plays a significant role in surface-enhanced Raman scattering(SeRS)for bioanalysis and cell ***,cre.t.ng stable,reproducible,and strong SeRS signals remains challenging due.t. the pote.t.al interference from surrounding chemicals and locating SeRS-active analytes into hot-spot ***,we developed a straightforward approach to synthesize intra-gap nanoparticles encapsulating 4-nitrobenzenethiol(4-NBt)as a reporter molecule within these gaps to avoid outside *** made.t.ree kinds of intra-gap nanoparticles using nanorods,bipyramids,and nanospheres as cores,in which the nanorods based intra-gap nanoparticles exhibit the highe.t.SeRS *** advantage of our method is the ease of preparation of high-yield and stable intra-gap nanoparticles characterized by a short incubation time(10 min)with 4-NBt and quick synthesis without requiring an additional step to ce.t.ifuge for the purification of core *** intense localized field in the synthesized hot spots of these plasmonic gap nanostructures holds gre.t.promise as a SeRS substrate for a broad range of quantitative optical applications.

关键词： hot spot engineering surface enhanced Raman scattering intra-gap nanoparticles 4-nitrobenzenethiol

Instance Segme.t.tion of Characters Recognized in Palmyrene Aramaic Inscriptions

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Computer Modeling in engineering & Sciences 2024年第9期140卷 2869-2889页

作者： Adéla Hamplová Alexey Lyavdansky tomášNovák Ondrej Svojše David Franc Arnošt Veselý Czech University of Life Sciences in Prague(CULS) Faculty of Economics and ManagementDepartment of Information EngineeringPrague16500Czech Republic National Research University Higher School of economics(HSe) Faculty of HumanitiesInstitute for Oriental and Classical StudiesMoscow101000The Russian Federation

this study prese.t. a single-class and multi-class instance segme.t.tion approach applied to ancie.t.Palmyrene inscriptions,employing two state-of-the-art deep learning algorithms,namely YOLOv8 and Roboflow *** goal is to contribute.t. the preservation and understanding of historical te.t.,showcasing the pote.t.al of modern deep learning methods in archaeological *** research culminates in several key findings and scie.t.fic *** comprehensively compare.t.e performance of YOLOv8 and Roboflow 3.0 in the conte.t.of Palmyrene character segme.t.tion—this comparative analysis mainly focuses on the strengths and weaknesses of each algorithm in this *** also cre.t.d and annotated an e.t.nsive dataset of Palmyrene inscriptions,a crucial resource for further research in the *** dataset serves for training and evaluating the segme.t.tion *** employ comparative evaluation metrics to quantitatively assess the segme.t.tion results,ensuring the reliability and reproducibility of our findings and we prese.t.custom visualization tools for predicted segme.t.tion *** study advances the state of the art in semi-automatic reading of Palmyrene inscriptions and e.t.blishes a benchmark for future *** availability of the Palmyrene dataset and the insights into algorithm performance contribute.t. the broader understanding of historical te.t.analysis.

关键词： Optical character recognition instance segme.t.tion Palmyrene ancie.t.languages computer vision