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Journal of Materials Science & Technology 2020年第14期47卷 15-24页

作者： Wonjoo lee Yuhyeong Jeong jae-Wook lee Howon lee Seong-hoon Kang Young-Min Kim Jonghun Yoon Department of Mechanical Design Engineering Hanyang University222Wangsimni-roSeongdong-guSeoul 04763Republic of Korea Materials Deformation Department Korea Institute of Materials Science797 ChangwondaeroSeongsan-guChangwon-siGyeongnam-do 51508Republic of Korea Department of Mechanical Engineering Hanyang University55 Hanyangdaehak-roSangnok-guAnsan-siGyeonggi-do 15588Republic of Korea

To predict the dendrite morphology and microstructure evolution in the solidification of molten metal,numerically,lattice Boltzmann method(LBM)-cellular automata(CA)model has been developed by integrating the LBM to solve the mass transport by diffusion and convection during solidification and the CA to determine the phase transformation with respect to the solid fraction based on the local equilibrium *** is successfully validated with analytic solutions such as Lipton-Glicksman-Kurz(LGK)model in static melt,and Oseen-Ivantsov solution under the fluid flow conditions in terms of tip radius and velocity of the dendrite *** proposed LBM-CA model does not only describe different types of dendrite formations with respect to various solidification conditions such as temperature gradient and growth rate,but also predict the primary dendrite arm spacing(PDAS)and the secondary dendrite arm spacing(SDAS),quantitatively,in directional solidification(DS)experiment with Ni-based superalloy.

关键词： Cellular automata(CA) Lattice Boltzmann method(LBM) Dendritic growth Directional solidification

What Causes the Springtime Tropospheric Ozone Maximum over Northeast Asia?

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Advances in Atmospheric Sciences 2010年第3期27卷 543-551页

作者： jae H.KIM Hyunjin lee Department of Atmospheric Science Pusan National University

Scientists have long debated the relative importance of tropospheric photochemical production versus stratospheric influx as causes of the springtime tropospheric ozone maximum over northern mid-latitudes. This paper investigates whether or not stratospheric intrusion and photochemistry play a significant role in the springtime ozone maximum over Northeast Asia, where ozone measurements are sparse. We examine how tropospheric ozone seasonalities over Naha （26°N, 128°E）, Kagoshima （31°N, 131°E）, and Pohang （36°N, 129°E）, which are located on the same meridional line, are related to the timing and location of the jet stream. The ozone seasonality shows a gradual increase from January to the maximum ozone month, which corresponds to April at Naha, May at Kagoshima, and June at Pohang. In order to examine the occurrence of stratospheric intrusion, we analyze a correlation between jet stream activity and tropospheric ozone seasonality. From these analyses, we did not find any favorable evidence supporting the hypothesis that the springtime enhancement may result from stratospheric intrusion. According to trajectory analysis for vertical and horizontal origins of the airmass, a gradual increasing tendency in ozone amounts from January until the onset of monsoon was similar to the increasing ozone formation tendency from winter to spring over China's Mainland, which has been observed during the build-up of tropospheric ozone over Central Europe in the winter-spring transition period due to photochemistry. Overall, the analyses suggest that photochemistry is the most important contributor to observed ozone seasonality over Northeast Asia.

关键词： tropospheric ozone photochemistry, stratospheric intrusion, jet stream activity, trajectory

Gost effectiveness of crack treatment methods:A field study

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Journal of Traffic and Transportation Engineering(English Edition) 2019年第6期6卷 598-607页

作者： Mithil Mazumder Hyun Hwan Kim Soon-jae lee Moon-Sup lee Materials Science Engineeringand Commercialization ProgramTexas State UniversitySan MarcosTX 78666USA Department of Engineering Technology Texas State UniversitySan MarcosTX 78666USA Korea Institute of Civil Engineering and Building Technology Gyeonggi-do 10223South Korea

In the United States,more than 94%highways are paved with asphalt materials and placing crack sealant materials has been a common pavement maintenance for *** sealing treatment includes the use of a router to create a reservoir on the intended cracks whereas crack filling is given without doing any modification to the crack *** the initial cost of crack sealing is higher,it is expected to have a longer service period compared to crack *** is little research on comparison of short and long term cost effectiveness between these two treatments using the real field cost data *** this study four test sites in Texas were treated with crack filling and sealing using the same sealant material and finishing *** effectiveness of both treatments was measured in terms of initial,annual average and life cycle cost based on the cost inputs during *** general,the results of this study indicated that(1)on an average approximately 45%initial cost increase was estimated with the two routing configurations of crack sealing;(2)material and labor cost is found to have the most significant effect on the higher initial cost of crack sealing compared to other associated costs;(3)annual average and life cycle costs have shown that crack sealing is more cost effective pavement maintenance compared to crack filling over a long period of time;(4)agency cost is observed to be reduced by approximately 24%with crack sealing treatment based on the35 year analysis period.

关键词： Crack sealing Crack filling Initial cost Annual average cost Life cycle cost

Prediction of Cold and Heat Patterns Using Anthropometric Measures Based on Machine Learning

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Chinese Journal of Integrative Medicine 2018年第1期24卷 16-23页

作者： Bum Ju lee jae Chul lee Jiho Nam Jong Yeol Kim Medical Research Division Korea Institute of Oriental Medicine

Objective： To examine the association of body shape with cold and heat patterns, to determine which anthropometric measure is the best indicator for discriminating between the two patterns, and to investigate whether using a combination of measures can improve the predictive power to diagnose these patterns. Methods： Based on a total of 4,859 subjects （3,000 women and 1,859 men）, statistical analyses using binary logistic regression were performed to assess the significance of the difference and the predictive power of each anthropometric measure, and binary logistic regression and Naive Bayes with the variable selection technique were used to assess the improvement in the predictive power of the patterns using the combined measures. Results： In women, the strongest indicators for determining the cold and heat patterns among anthropometric measures were body mass index （BMI） and rib circumference; in men, the best indicator was BMI. In experiments using a combination of measures, the values of the area under the receiver operating characteristic curve in women were 0.776 by Naive Bayes and 0.772 by logistic regression, and the values in men were 0.788 by Naive Bayes and 0.779 by logistic regression. Conclusions： Individuals with a higher BMI have a tendency toward a heat pattern in both women and men. The use of a combination of anthropometric measures can slightly improve the diagnostic accuracy. Our findings can provide fundamental information for the diagnosis of cold and heat patterns based on body shape for personalized medicine.

关键词： cold and heat patterns personalized medicine cold syndrome predictive power machine learning data mining

Effect of production process on performance properties of warm rubberized binders

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Journal of Traffic and Transportation Engineering(English Edition) 2019年第6期6卷 589-597页

作者： Hyun Hwan Kim Mithil Mazumder Soon-jae lee Moon-Sup lee Department of Engineering Technology Texas State UniversitySan MarcosTX 78666USA Korea Institute of Civil Engineering and Building Technology Gyeonggi 411-712South Korea

The study presents an experimental evaluation of performance properties of two different production processes of warm rubberized *** types of rubberized binder were produced through dry process and wet process and two of the available wax additives were added into the rubberized binders(i.e.,LEADCAP and Sasobit).Rubberized binders with wax additives were artificially short-term and long-term aged using the rolling thin film oven(RTFO) and pressure aging vessel(PAV) *** binder tests were carried out on the binders through the rotational viscometer(RV),the dynamic shear rheometer(DSR),and the bending beam rheometer(BBR).In general,the results of this study indicated that(1) the viscosity properties have been found to be similar between dry and wet processes,(2) the rubberized binders manufactured by wet process were observed to have the higher rutting resistance than those by dry process,(3) the wet process resulted in better performance in the fatigue cracking test than the dry process,and(4) the blending method was found to have little influence of stiffness properties.

关键词： Rubberized binder Dry process Wet process Viscosity Rutting Fatigue cracking

Colored ultrathin hybrid photovoltaics with high quantum efficiency

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Light(Science & Applications) 2014年第1期3卷 36-42页

作者： Kyu-Tae lee jae Yong lee Sungyong Seo L Jay Guo Department of Electrical Engineering and Computer Science The University of MichiganAnn ArborMichigan 48109USA

Most current solar panels are fabricated via complex processes using expensive semiconductor materials,and they are rigid and heavy with a dull,black *** a result of their non-aesthetic appearance and weight,they are primarily installed on rooftops to minimize their negative impact on building *** large surfaces and interiors of modern buildings are not efficiently utilized for potential electric power ***,we introduce dual-function solar cells based on ultrathin dopant-free amorphous silicon embedded in an optical cavity that not only efficiently extract the photogenerated carriers but also display distinctive colors with the desired angle-insensitive ***-energy-harvesting colored signage is ***,a cascaded photovoltaics scheme based on tunable spectrum splitting can be employed to increase power efficiency by absorbing a broader band of light *** study pioneers a new approach to architecturally compatible and decorative thin-film photovoltaics.

关键词： color filters nanocavities organic–inorganic nanostructures photovoltaics spectrum splitting

Expression rates of p16,p53 in head and neck cutaneous squamous cell carcinoma based on human-papillomavirus positivity

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World Journal of Clinical Cases 2025年第9期13卷 13-23页

作者： Ha-Jong Nam Heongrae Ryu Da-woon lee Je Yeon Byeon Jun Hyuk Kim Ji Hye lee Soomin Lim Hwan Jun Choi Department of Plastic and Reconstructive Surgery Soonchunhyang University Gumi HospitalGumi-si 39371South Korea Department of Plastic and Reconstructive Surgery College of MedicineSoonchunhyang UniversityCheonan-si 31151South Korea Department of Pathology Soonchunhyang University HospitalCheonan-si 31151South Korea Bachelor of Medicine and Bachelor of Surgery University College LondonMedical SchoolLondon WC1E 6DEUnited Kingdom

BACKGROUND The high prevalence of human papillomavirus(HPV)infection in oropharyngeal squamous cell carcinoma(SCC)is well established,and p16 expression is a strong ***-related tumors exhibit unique mechanisms that target p16 and p53 ***,research on HPV prevalence and the combined predictive value of p16 and p53 expression in head and neck cutaneous SCC(HNCSCC),particularly in Asian populations,remains *** retrospective study surveyed 62 patients with HNSCC(2011-2020),excluding those with facial warts or other skin *** To explore the prevalence of HPV and the predictive value of p16 and p53 expression in HNCSCC in Asian *** All patients underwent wide excision and *** staining for HPV,p16,and p53 yielded positive and negative *** relevance of each marker was investigated by categorizing the tumor locations into high-risk and middle-risk zones based on recurrence *** Of the 62 patients,20(32.26%)were male,with an average age of 82.27 years(range 26-103 years).High-risk included 19 cases(30.65%),with the eyelid and lip being the most common sites(five cases,8.06%).Middle-risk included 43 cases(69.35%),with the cheek being the most common(29 cases,46.77%).The p16 expression was detected in 24 patients(38.71%),p53 expression in 42 patients(72.58%),and HPV in five patients(8.06%).No significant association was found between p16 expression and the presence of HPV(P>0.99),with a positive predictive value of 8.33%.CONCLUSION This study revealed that p16,a surrogate HPV marker in oropharyngeal SCC,is not reliable in HNCSCC,providing valuable insights for further research in Asian populations.

关键词： Squamous cell carcinoma Oropharyngeal Non-oropharyngeal Human papillomavirus The p16 The p53

Milk protein-shelled gold nanoparticles with gastrointestinally active absorption for aurotherapy to brain tumor

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Bioactive Materials 2022年第2期7卷 35-48页

作者： Hyung Shik Kim Seung jae lee Dong Yun lee Department of Bioengineering College of Engineeringand BK FOUR Biopharmaceutical Innovation Leader for Education and Research GroupHanyang UniversitySeoul04763Republic of Korea Institute of Nano Science and Technology Hanyang UniversitySeoul04763Republic of Korea

Orally absorbable gold nanoparticles(AuNP)having cancer ablation therapy is strongly demanded to treat glioblastoma multiforme(GBM)for patients with its highest incidence ***,we develop a milk protein lactoferrin-conjugated AuNP for its oral absorption and targeting to the GBM through the interaction between lactoferrin(Lf)and lactoferrin receptor(LfR)that is highly expressed in the intestine,blood-brain barrier and *** stability and long circulation of AuNP,glutathione and polyethylene glycol(PEG)is introduced,which is called to *** Lf-PEG-AuNP are orally administered to orthotopic GBM-bearing mice,11-fold and 8-fold higher concentrations of AuNP are measured in bloodstreams and GBM in the brain,respectively,compared with ***,orally administered Lf-PEG-AuNP exhibit an outstanding temperature rise in GBM by irradiating laser and significantly reduce tumor ***,we suggest that the Lf-PEG-AuNP can fundamentally target GBM in the brain through oral absorption,and that its efficient photothermal therapy is possible.

关键词： intestine absorption gastrointestinal

Uncertainty Assessment of Soil Erosion Model Using Particle Filtering

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Journal of Mountain Science 2015年第4期12卷 828-840页

作者： Yeonsu KIM Giha lee Hyunuk AN jae E YANG International Water Resources Research Institute Chungnam National University Dept.of Construction & Disaster Prevention Eng. Kyungpook National University Dept.of Agricultural & Rural Eng. Chungnam National University Dept.of Biological Environment Kangwon National University

Recent advances in computer with geographic information system(GIS) technologies have allowed modelers to develop physics-based models for modeling soil erosion processes in time and ***, it has been widely recognized that the effect of uncertainties on model predictions may be more significant when modelers apply such models for their own modeling *** of uncertainty involved in modeling include data, model structural, and parameter *** deal with the uncertain parameters of a catchment-scale soil erosion model(CSEM) and assess simulation uncertainties in soil erosion, particle filtering modeling(PF) is introduced in the *** proposed method, CSEM-PF, estimates parameters of non-linear and non-Gaussian systems, such as a physics-based soil erosion model by assimilating observation data such as discharge and sediment discharge sequences at *** provides timevarying feasible parameter sets as well as uncertainty bounds of outputs while traditional automatic calibration techniques result in a time-invariant global optimal parameter ***-PF was applied to a small mountainous catchment of the Yongdamdam in Korea for soil erosion modeling and uncertainty assessment for three historical typhoon ***, the most optimal parameter sets and uncertainty bounds of simulation of both discharge and sediment discharge at each time step of the study events are provided.

关键词： Data assimilation Particle filter Soil erosion modeling Parameter estimation Time variant parameter Mountainous catchment

Autonomous Optimal Coordination Scheme in Protection System of Power Distribution Network by Using Multi-Agent Concept

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Transactions of Tianjin University 2008年第2期14卷 106-111页

作者： lee Seung-jae KIM Tae-Wan lee Gi-Young Next-Generation Power System Technology Center Myongji UniversityYongin449-728KyunggidoKorea

A protection system using a multi-agent concept for power distribution networks is *** digital over current relay(OCR)is developed as an agent by adding its own intelligence,self-tuning and communication *** main advantage of the multi-agent concept is that a group of agents work together to achieve a global goal which is beyond the ability of each individual *** order to cope with frequent changes in the network operation condition and faults,an OCR agent,proposed in this paper,is able to detect a fault or a change in the network and find its optimal parameters for protection in an autonomous manner considering information of the whole network obtained by communication between other *** this kind of coordination and information exchanges,not only a local but also a global protective scheme is *** in a simple distribution network show the effectiveness of the proposed protection system.

关键词： multi-agent system over current relay(OCR) communication protection of distribution network