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Effect of tamsulosin on ejaculatory function in BPH/LUTS

Asian Journal of Andrology 2011年第6期13卷 846-850页

作者： Sang Hoon Song Hwancheol Son Kwang Taek Kim Sae Woong Kim Du Geon Moon Ki Hak Moon Kwangsung Park Jong Kwan Park Sung-Won Lee jae Seog Hyun Nam Cheol Park Jeungpyung Health Center Jeungpyung-gun Chungbuk 368-900 Korea Department of Urology Seoul Metropolitan Boramae Hospital Seoul 156-707 Korea Aerospace Medical Center Cheongwon Chungbuk 363-840 Korea Catholic University of Korea College of Medicine Seoul 137-701 Korea Korea University College of Medicine Seoul 152-703 Korea Department of Urology Yeungnam University College of Medicine Daegu 705-717 Korea Department of Urology Chonnam National University Medical School Gwangju 501-757 Korea Department of Urology Medical School and Institute for Medical Sciences Chonbuk National University Chonbuk 561-712 Korea Research Institute of Clinical Medicine and CTC for Medical Device of Chonbuk National University Hospital Chonbuk 561-712 Korea Samsung Medical Center Sungkyunkwan University School of Medicine Seoul 135-710 Korea Gyeongsang National University Gyeongnam 660-702 Korea pusan National University College of Medicine Pusan 602-739 Korea

This study was undertaken to determine the impact on ejaculatory function of tamsulosin （0.2 mg） given once daily （OD） for 12 weeks and to identify risk factors for ejaculatory dysfunction in patients undergoing this treatment. Males with an International Prostatic Symptom Score （IPSS） ≥ 8 were enrolled in this study. All participants completed questionnaires, including the IPSS and the Male Sexual Health Questionnaire （MSHQ）, and serum prostate-specific antigen, transrectal ultrasound and uroflowmetry with post-void residual were measured. After initiating 0.2 mg OD tamsulosin, patients were re-evaluated on the fourth and twelfth weeks of medication. The chi-squared test, the independent t-test and one-way ANOVA were used to compare means. Binary logistic regression analysis was used to calculate the odds ratio for all risk factors. A total of 177 men constituted the study cohort. No significant difference was observed between baseline and follow-up for the erectile function, ejaculatory function, satisfaction, sexual activity and desire domains （EFD, EjFD, SDA and ADD） or for erectile or ejaculatory bother mean scores. After 12 weeks, the overall incidence of ejaculatory dysfunction （EjD） was 13.4%. Incidences of the seven different types of EjD （decreased frequency, delay, dryness, decreased strength/force, decreased volume, decreased pleasure and pain at ejaculation） were 2.4%, 3.1%, 3.9%, 3.9%, 6.3%, 7.1% and 3.1%, respectively. Baseline EjFD scores were higher for I PSS responders than for non-responders （26.09 vs. 24.06, P=0.03）. An EjFD score reduction was more frequent in IPSS responders. The incidence of EjD was small, but not negligible and was more frequent in patients with less lower urinary tract symptoms, a smaller prostate, higher baseline MSHQ totals and higher EjFD scores.

关键词： alpha-1 adrenergic receptors benign prostatic hyperplasia ejaculation lower urinary tract symptom Male Sexual HealthQuestionnaire prostatic hyperplasia tamsulosin

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Effect of Curing Poly(<i>p</i>-Phenylene Sulfide) on Thermal Properties and Crystalline Morphologies

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Advances in Chemical Engineering and Science 2013年第2期3卷 145-149页

作者： Sungho Lee Do-Hwan Kim jae-Ha Park Min Park Han-Ik Joh Bon-Cheol Ku Carbon Convergence Materials Research Center Institute of Advanced Composites Materials Korea Institute of Science and Technology Wanju-gun Republic of Korea

Commercial poly(p-phenylene sulfide) (PPS) was thermally cured, which resulted in an increase of molecular weight due to cross-linking. Non-isothermal crystallization studies of samples cured for up to 7 days at 250?C showed a monotonous increase of crystallization temperature compared to pure PPS. However, a further increase of curing time decreased the crystallization temperature. The change in the half-crystallization time (t1/2) was similar to the crystallization temperature. Thus, the cross-linking of PPS affected crystallization behaviors significantly. To a certain extent, crosslinks acted as nucleation agents, but excessive cross-linking hindered the crystallization. Morphologies observed by polarized optical microscopy suggested that thermal curing for as little as 1 day contributed to the spherulitic structure having a smaller size, that was not observed with pure PPS.

关键词： Poly(p-Phenylene Sulfide) Thermal Curing Non-Isothermal Crystallization Cross-Linking Crystalline Morphologies

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Anti-inflammatory and Anti-oxidative Effects of the Ethanol Extract of Cryptocarya densiflora Blume in Lipopolysaccharide-Stimulated RAW264,7 Mouse Macrophages

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Journal of Pharmacy and Pharmacology 2014年第1期2卷 26-37页

作者： Ji-Won Park Ok-Kyoung Kwon Doo-Young Kim Jung-Hee Kim In Sik Shin Sei-Ryang Oh Sang-Woo Lee jae-Hong Kim Hang Jin Wan Yi Lee Kyung-Seop Ahn Natural Medicine Research Center Korea Research Institute of Bioscience and Biotechnology 30 Yeongudanji-ro Ochang-eupCheongwon-gun Chungbuk 363-883 Republic of Korea College of Life Sciences and Biotechnology University of Korea Anam-dong 5-ga Seongbuk-gu Seoul 136-701 Republic ofKorea Department of Toxicology College of Pharmacy University of Chungnam National Yuseong-gu Daejeon 305-764 Republic ofKorea International Biological Material Research Center Research Institute of Bioscience and Biotechnology Yuseong-gu Daejeon305-806 Republic of Korea Yunnan Academy of Agricultural Sciences Medicinal Plants Research Institute Beijing 2238 China

CD (Cryptocarya densiflora) Blume has traditionally been used as an herbal medicine. In this study, the effects of CDEE (CD ethanol extract) on inflammation were investigated in LPS (lipopolysaccharide)-stimulated mouse RAW264.7 macrophages. We investigated the effects of CDEE on the production of NO, PGE2 interleukin (IL)-6, IL-1β, and tumor necrosis factor (TNF)-α in LPS-stimulated RAW264.7 cells. We measured the mRNA or protein expression of the pro-inflammatory mediators induced by CDEE in LPS-stimulated RAW264.7 cells. We explored the expression of Nrf-2, heme oxygenase (HO)-1 and NADPH-quinone oxidoreductase (NQO)-1 to elucidate the antioxidative mechanisms. CDEE significantly inhibited the production of NO, PGE2, IL-6, IL-1β and TNF-α in LPS-stimulated RAW264.7 cells. CDEE suppressed the mRNA or protein expression of iNOS, COX-2, and the MAPKs with a reduction in the translocation of NF-κB in LPS-stimulated RAW264.7 cells. In addition, CDEE significantly increased the expression of HO-1 and NQO-1 with an increase in the translocation of Nrf-2 into the nucleus. These results indicate that CDEE inhibits the LPS-induced inflammatory and oxidative responses via suppression of NF-κB activation and the enhancement of Nrf2 activation. We suggest that CDEE may be therapeutic for treating inflammatory diseases.

关键词：药剂学药理学药学数学物理学化学

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Correction to:Adaptive Electrospinning System Based on Reinforcement Learning for Uniform‑Thickness Nanofiber Air Filters

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Advanced Fiber Materials 2023年第2期5卷 695-695页

作者： Seok Hyeon Hwang Jin Yeong Song Hyun Il Ryu jae Hee Oh Seungwook Lee Donggeun Lee Dong Yong Park Sang Min Park School of Mechanical Engineering Pusan National University63‑2 Busan University‑roGeumjeong‑guBusan 46241South Korea Smart Manufacturing Technology R&D Group Korea Institute of Industrial Technology320 Techno Sunhwan‑roYuga‑eupDalseong‑gunDaegu 42994Republic of Korea

Correction to:Advanced Fiber Materials https://***/10.1007/s42765-022-00247-3 In this article the author name Dong Yong Park was incorrectly written as Dong Young *** original article has been ***'s Note Springer Natu... 详细信息

关键词： Uniform neutral corrected

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禅让还是篡夺?——中国古代王权神话解构分析

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长江大学学报（社会科学版） 2018年第6期41卷 1-7,26页

作者：郑在书崔丽红李定河韩国梨花女子大学中文系韩国东国大学中文系北京大学中文系北京100871

以尧舜禅让、鲧禹治水及成汤祈雨神话为中心,分析考察这些神话所反映的现实及神话原型,将这些神话和中国境外一些神话及周边民族神话进行比较,并结合文明化历史之前的社会暴力现实,对这些神话进行了解构和剖析。得出如下结论:尧舜禅让... 详细信息

以尧舜禅让、鲧禹治水及成汤祈雨神话为中心,分析考察这些神话所反映的现实及神话原型,将这些神话和中国境外一些神话及周边民族神话进行比较,并结合文明化历史之前的社会暴力现实,对这些神话进行了解构和剖析。得出如下结论:尧舜禅让神话是根据儒家的理想主义和墨家的尚贤思想编写而成的故事,其中所讲的"禅让",实际上是动用武力实现政权交替的一种政治事件;而鲧禹治水神话是权力之争使父子间发生冲突,导致出现杀父行为的一出悲剧;成汤祈雨神话虽把成汤美化为爱民圣君,但事实上成汤作为巫君遭杀害的可能性极大。这种认识能够使我们摆脱帝王世系的束缚,从断裂和非连续性层面上来理解中国古代王权。这能够给我们提供新的思考空间。人们普遍认为,中国神话没有被文学化或体系化,但从上述结论来看,中国神话与西方神话相比较而言,它已经在相当大的程度上被人文化了,只是其层次不同而已。在此,我们还应关注中国传统文化机制,这种机制是形成现存中国神话特质及模式的重要基础。

关键词：禅让放伐暴力周边文化帝王世系文化机制

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韩国乌龟(Mauremys reevesii)的分布及季节性移动距离研究(英文)

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野生动物学报 2014年第3期35卷 329-334页

作者：宋栽永张敏昊具教盛韩国国立公团研究所济州国立大学

为确定韩国乌龟(Mauremys reevesii)的地理分布及生境状况,作者采用活捕和直接观察法全面调查了韩国所有国家公园及其附近地区,同时,在全罗南道求礼郡利用无线电发射器跟踪法研究测定了乌龟的家域。研究结果显示,在韩国共有60处观察到... 详细信息

为确定韩国乌龟(Mauremys reevesii)的地理分布及生境状况,作者采用活捕和直接观察法全面调查了韩国所有国家公园及其附近地区,同时,在全罗南道求礼郡利用无线电发射器跟踪法研究测定了乌龟的家域。研究结果显示,在韩国共有60处观察到乌龟的分布,且多集中在韩国的南半部;最大季节性移动距离达196 m,在统计学上未出现个体间差异,但实际测量距离仍可发现较大差异;在韩国乌龟的家域确定为2.8~6.1 hm^2之间。

关键词：乌龟(Mauremys reevesii) 分布移动距离家域

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