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Comparative study on machinability improvement in hard turning using coated and uncoated carbide inserts： part II modeling, multi-response optimization, tool life, and economic aspects

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Advances in Manufacturing 2018年第2期6卷 155-175页

作者： Ramanuj Kumar Ashok Kumar Sahoo Purna chandra Mishra Rabin Kumar das School of Mechanical Engineering Kalinga Institute of Industrial Technology Bhubaneswar-24 Odisha India

The present study focused on mathematical modeling, multi response optimization, tool life, and eco- nomical analysis in finish hard turning of AISI D2 steel （（55 4- 1） HRC） using CVD-coated carbide （TiN/TiCN/ A1203） and uncoated carbide inserts under dry environ- mental conditions. Regression methodology and the grey relational approach were implemented for modeling and multi-response optimization, respectively. Comparative economic statistics were carried out for both inserts, and the adequacy of the correlation model was verified. The experimental and predicted values for all responses were very close to each other, implying the significance of the model and indicating that the correlation coefficients were close to unity. The optimal parametric combinations for A1203 coated carbide were dl-fl-v2 （depth of cut = 0.1 mm, feed = 0.04 mm/r and cutting speed = 108 m/min）, and those for the uncoated tool were dl-（0.1 mm）-fl （0.04 mm/r）-vl （63 rn/min）. The observed tool life for the coated carbide insert was 15 times higher than that for the uncoated carbide insert, considering flank wear criteria of 0.3 mm. The chip volume after machining for the coated carbide insert was 26.14 times higher than that of the uncoated carbide insert and could be better utilized for higher material removal rate. Abrasion, diffusion, notch- ing, chipping, and built-up edge have been observed to be the principal wear mechanisms for tool life estimation. Use of the coated carbide tool reduced machining costs by about 3.55 times compared to the use of the uncoated carbide insert, and provided economic benefits in hard turning.

关键词： Machinability Hard turning Regression Grey relational analysis Tool life Economic analysis

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Comparative investigation towards machinability improvement in hard turning using coated and uncoated carbide inserts： part Iexperimental investigation

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Advances in Manufacturing 2018年第1期6卷 52-70页

作者： Ramanuj Kumar Ashok Kumar Sahoo Purna chandra Mishra Rabin Kumar das School of Mechanical Engineering Kalinga Institute of Industrial Technology BhubaneswarOdisha 751024 India

The investigation of low cost uncoated andcoated carbide insert in the hard turning of hardened AISID2 steel （≥55 HRC） will definitely open up a new arena asan economical alternative suitable to industrial machiningsectors. Thus, this paper reports the comparative machin-ability assessment for the hard turning of AISI D2 steel（（55 ± 1） HRC） by coated and uncoated carbide insert in adry environment. Micro hardness and abrasion tests werecarried out to assess resistance capability against wear. Theabove test results confirmed the greater wear resistanceability of AIaO3 coated carbide insert over uncoated car-bide. Based on the extensive investigation of comparativemachinability, the coated carbide insert （TiN-TiCN-A12O3）outperformed the uncoated carbide insert with regard tosurface roughness, flank wear, chip-tool interface temper-ature, and chip morphology. Abrasion and diffusion wereobserved as the principal tool wear mechanisms in theinvestigated range. The uncoated carbide failed completelydue to the severe chipping and quick dulling of the cuttingedge, which led to its unsuitability for machining hardenedsteel.

关键词： Coated and uncoated carbide Hard turning Machinability Flank wear Surface roughness Chipmorphology Cutting temperature

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Performance analysis of a thick copper-electroplated FDM ABS plastic rapid tool EDM electrode

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Advances in Manufacturing 2018年第4期6卷 442-456页

作者： Saroj Kumar Padhi S. S. Mahapatra Rosalin Padhi Harish chandra das Department of Mechanical Engineering Koneru Lakshmiah Education Foundation Deemed to be University Vaddeswarm 522502 India Department of Mechanical Engineering National Institute of Technology Rourkela Rourkela 76900& India Department of Physics Berhampur University Berhampur 760007 India Department of Mechanical Engineering National Institute of Technology Meghalaya Shillong 793003 India

The importance of rapid tooling (RT) and additive manufacturing (AM) appears to be indispensable for boosting the process of manufacturing and expanding the horizon of production technology worldwide. This concept draws the attention of numerous scholars to arrive at a conclusive theory for the widespread utilization of RT. This study attempts to determine the viability and performance of an RT electrode in the field of electro discharge machining (EDM). The electrode prototype is made using an acrylonitrile butadiene styrene (ABS) plastic by fused deposition modeling (FDM), an AM technique, electroplated with copper of desired thickness, and used in die sinking EDM of D2 steel. The scanning electron microscope analysis of the electroplated samples confirms that it is possible to obtain the desired thickness of the metal by electroplating on any electrically conductive surfaces. In the present work, an experimental study is performed for examining the electroplated copper thickness of the plastic EDM electrode and its performances. It is found that the electroplated ABS plastic EDM RT electrode successfully performs the machining operation of D2 steel, and the results are comparable with a solid electrode. The study reveals that the RT electrode can be regarded as a viable tool for rough cutting or semi-finishing cut EDM functions. The experimental results are thoroughly discussed, examined, analyzed, and evaluated for the purpose of developing the appropriate form of the concept.

关键词： Additive manufacturing (AM) Fused deposition modeling (FDM)-Metallization of acrylonitrile butadiene styrene (ABS) plastic Reduced silver colloidal Rapid tooling (RT) Electro discharge machining (EDM)

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Pharmacokinetics and Bioequivalence of Dienogest in Healthy Bangladeshi Female Volunteers: An Open-Label, Single-Dose, Randomized, Two-Way Crossover Study

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Open Journal of Obstetrics and Gynecology 2024年第5期14卷 779-789页

作者： Nusrat Mahmud Nafisa Ahamed Uttom Kumar Bhowmik Sabrina Akter Tushi Nayan Ghosh Nithon chandra Sahana Arifa Akram Md. Alimur Reza BIRDEM General Hospital Dhaka Bangladesh Medical College for Women & Hospital Dhaka Bangladesh Novus Clinical Research Services Ltd. Dhaka Bangladesh National Institute of Laboratory Medicine & Referral Centre (NILMRC) Dhaka Bangladesh

Background: Dienogest is a potential treatment for pelvic pain associated with endometriosis, a condition of significant concern in gynaecology. The current study was conducted as a crossover-randomized bioequivalence assessment of two oral Dienogest 2 mg formulations, aiming to provide valuable insights for healthcare professionals and researchers in this field. Objective: The primary aim of this research was to evaluate and compare the pharmacokinetic characteristics of Dienogest 2 mg tablets. Dinogest (Dienogest 2 mg) tablets, manufactured by Nuvista Pharma Limited in Bangladesh, and Visanne (Dienogest 2 mg) tablets, manufactured by Bayer Pharma in Germany, were the test and reference formulations, respectively. Materials and Method: The study was an open-label, balanced, randomized, two treatments, two sequences, two periods, two-way crossover, laboratory blind, single oral dose bioequivalence study conducted in healthy adult females under fasting conditions. The study was carried out on 13 healthy, non-pregnant female subjects, and all the subjects completed both study periods with a 15-day washout in between. Randomization was used to assign the test and reference formulations to the subjects. Following each oral administration, a series of blood samples were obtained at different time intervals from pre-dose to 72 hours post-dose and analyzed for Dienogest concentrations using a validated bio-analytical method. A standard non-compartmental model was used to analyze the pharmacokinetic parameters. The primary pharmacokinetic parameters were peak plasma drug concentration (Cmax), the area under the plasma concentration-time curve from time zero to time t (AUC0–t), and AUC from t = 0 to infinity (AUC0–∞). The other PK parameters included time to reach Cmax (Tmax), terminal elimination rate constant (Kel), and half-life (t1/2). Result: The ratios and 90% CI for the geometric mean test/re

关键词： Dienogest Bioequivalence Study Endometriosis Novus CRSL

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Stable Fano-like plasmonic resonance: its impact on the reversal of far-and near-field optical binding force

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Communications in Theoretical Physics 2020年第4期72卷 89-105页

作者： Hamim Mahmud Rivy M R C Mahdy Nabila Masud Ziaur Rahman Jony Saikat chandra das Department of Electrical&Computer Engineering North South UniversityBashundharaDhaka1229Bangladesh School of Electrical and Electronic Engineering Nanyang Technological University50 Nanyang Ave639798 Singapore Pi Labs Bangladesh LTD ARA Bhaban39Kazi Nazrul Islam AvenueKawran BazarDhaka 1215Bangladesh

Even for a 100 nm interparticle distance or a small change in particle shape,optical Fano-like plasmonic resonance mode usually vanishes *** would be remarkable if stable Fano-like resonance could somehow be achieved in distinctly shaped nanoparticles for more than 1μm interparticle distance,which corresponds to the far electromagnetic field *** such far-field Fano-like plasmonic resonance can be achieved,controlling the reversal of the far-field binding force can be attained,like the currently reported reversals for near-field *** this work,we have proposed an optical set-up to achieve such a robust and stable Fano-like plasmonic resonance,and comparatively studied its remarkable impact on controlling the reversal of near-and far-field optical binding *** our proposed set-up,the distinctly shaped plasmonic tetramers are half immersed(***-benzene)in an inhomogeneous dielectric interface and illuminated by?circular?polarized *** have demonstrated significant differences between near-and far-field optical binding forces along with the Lorentz force field,which partially depends on the object’s shape.A clear connection is shown between the far-field binding force and the resonant modes,along with a generic mechanism to achieve controllable Fano-like plasmonic resonance and the reversal of the optical binding force in both far-and near-field configurations.

关键词： Fano resonance optical binding force Lorentz force plasmonic tetramer

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Pharmacokinetic Comparison and Bioequivalence Evaluation of Two 20-mg Vonoprazan Fumarate Tablets in Bangladeshi Healthy Male Subjects

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Journal of Biosciences and Medicines 2024年第8期12卷 230-243页

作者： Md. Alimur Reza Uttom Kumar Bhowmik Sabrina Akter Tushi Nayan Ghosh Nithon chandra Sahana Md. Ashraful Islam Nafisa Ahamed Arifa Akram Novus Clinical Research Services Ltd. Dhaka Bangladesh Medical College for Women & Hospital Dhaka Bangladesh National Institute of Laboratory Medicine & Referral Centre (NILMRC) Dhaka Bangladesh

Background: Vonoprazan fumarate, a novel potassium-competitive acid blocker, outperforms traditional proton pump inhibitors in acid suppression and can be effectively combined with antibiotics to eradicate Helicobacter pylori. Objective: The study aimed to determine if two Vonoprazan formulations—Vonoprazan Fumarate 20 mg Tablet of Beximco Pharmaceuticals Limited, Bangladesh (test product) and Takecab 20 mg Tablet of Takeda Pharmaceutical Company Limited, Japan (reference product)—met FDA’s bioequivalence requirements by comparing their pharmacokinetic characteristics in healthy Bangladeshi adults. Methods: This was a single-center, randomized, open-label, two-period, two-sequence, laboratory-blind, double-crossover experiment. After 10 hours of fasting, 18 subjects were randomly assigned to receive a single oral dose of either formulation. During each treatment period, blood samples were collected at specific times (pre-dose and up to 48 hours post-dose) to measure plasma Vonoprazan levels using liquid chromatography-tandem mass spectrometry. A non-compartmental model was used to calculate pharmacokinetic parameters using the plasma drug concentration-time profile. A statistical comparison of the pharmacokinetic parameters of the two formulations of the test and reference product was conducted using SAS® statistical software to assess the bioequivalence. Primary pharmacokinetic parameters (Cmax, AUC0-t, and AUC0-∞) and secondary parameters (Tmax, T1/2, Kel, and AUC extrapolation) were calculated for both drug formulations. If the confidence intervals for the natural log-transformed Cmax, AUC0-t, and AUC0-∞ values fell between 80% and 125%, the drug products would be considered bioequivalent. Result: The geometric mean ratio of Vonoprazan between the test and reference groups was found to be 109.04% (99.47% - 119.53%), 101.37% (95.58% - 107.50%), and 101.24% (95.43% - 107.41%), with 90% confidence intervals (CIs) for the Cmax, AUC0–t, and AUC0–∞, and these outcomes

关键词： Bioequivalence Vonoprazan Pharmacokinetics

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Analysis and use of fuzzy intelligent technique for navigation of humanoid robot in obstacle prone zone

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Defence Technology（防务技术） 2018年第6期14卷 677-682页

作者： Asita Kumar Rath Dayal R.Parhi Harish chandra das Manoj Kumar Muni Priyadarshi Biplab Kumar Centre of Biomechanical Science Siksha O'Anusandhan Deemed to be University Robotics Laboratory Mechanical Engineering DepartmentNational Institute of Technology(India) Mechanical Engineering Department National Institute of Technology(India)

With the increasing use of humanoid robots in several sectors of industrial automation and manufacturing, navigation and path planning of humanoids has emerged as one of the most promising area of research. In this paper, a navigational controller has been developed for a humanoid by using fuzzy logic as an intelligent algorithm for avoiding the obstacles present in the environment and reach the desired target position safely. Here, the controller has been designed by careful consideration of the navigational parameters by the help of fuzzy rules. The sensory information regarding obstacle distances and bearing angle towards the target are considered as inputs to the controller and necessary velocities for avoiding the obstacles are obtained as outputs. The working of the controller has been tested on a NAO humanoid robot in V-REP simulation platform. To validate the simulation results, an experimental platform has been designed under laboratory conditions, and experimental analysis has been ***, the results obtained from both the environments are compared against each other with a good agreement between them.

关键词： Humanoid robot Navigation Path planning Fuzzy

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Ion Conduction in Superionic Glassy Electrolytes:An Overview

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Journal of Materials Science & Technology 2013年第3期29卷 193-208页

作者： Angesh chandra Alok Bhatt Archana chandra Department of Applied Physics Shri Shankaracharya Institute of Prof.Manag.& Tech.Raipur 492015C.G.India Department of Applied Physics M.P Christian College of Engg.& Tech.Bhilai 490026C.G.India

The various theoretical and experimental models for ion conduction mechanism of fast ion conducting （FIC） glass electrolytes have been reported in the present review paper. Some characterization techniques of FIC glasses are presented. The experimental methods for determination of some ion transport parameters viz ionic conductivity （σ）, ionic mobility （μ）, mobile ion concentration （n）, ionic drift velocity （Vd）, ionic transference number （tion） and activation energies of FIC glasses are explained. The solid state battery fabrication by using some FIC glasses is also reported.

关键词： Ion conduction Glassy solid electrolyte Fast ion conducting (FIC) glass Superionic solid Relaxation phenomenon

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Characterization,spectroscopic investigation of defects by positron annihilation,and possible application of synthesized PbO nanoparticles

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Chinese Physics B 2021年第2期30卷 400-407页

作者： Sk Irsad Ali Anjan das Apoorva Agrawal Shubharaj Mukherjee Maudud Ahmed P M G Nambissan Samiran Mandal Atis chandra Mandal Department of Physics University of BurdwanGolapbagBurdwan 713104West BengalIndia Department of Physics A.P.C.Roy Government CollegeSiliguriDarjeeling 734010West BengalIndia Applied Nuclear Physics Division Saha Institute of Nuclear Physics1/AF BidhannagarKolkata 700064India Department of Physics Government General Degree College at PedongKalimpong 734311West BengalIndia

Nanocrystalline samples of highly pure lead oxide were prepared by the sol-gel route of synthesis.X-ray diffraction and transmission electron microscopic techniques confirmed the nanocrystallinity of the samples,and the average sizes of the crystallites were found within 20 nm to 35 *** nanocrystallites exhibited specific anomalous properties,among which a prominent one is the increased lattice parameters and unit cell *** optical band gaps also increased when the nanocrystallites became smaller in *** latter aspect is attributable to the onset of quantum confinement effects,as seen in a few other metal oxide *** annihilation was employed to study the vacancy type defects,which were abundant in the samples and played crucial roles in modulating their *** defect concentrations were significantly larger in the samples of smaller crystallite *** results suggested the feasibility of tailoring the properties of lead oxide nanocrystallites for technological applications,such as using lead oxide nanoparticles in batteries for better performance in discharge rate and *** also provided the physical insight into the structural build-up process when crystallites were formed with a finite number of atoms,whose distributions were governed by the site stabilization energy.

关键词： lead oxide nanocrystals positron annihilation sol-gel processes

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Prevalence of Mastitis and Associated Risk Factors in Lactating Camels (Camelus Dromedarius) on Dairy Farms in Benadir Region, Somalia

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Open Journal of Veterinary Medicine 2024年第6期14卷 111-123页

作者： Shafii Abdullahi Mohamed Mahad Mohamud Abdi Abdiaziz Idiris Mohamud Yonis Abukar Mohamed Ahmed Ali Omar Abdirahman Barre chandra Shaker Chouhan Md. Amimul Ehsan Faculty of Veterinary Science Benadir University Mogadishu Somalia Faculty of Veterinary Medicine and Animal Husbandry Somali National University Mogadishu Somalia Somali Animal Welfare Society (SAWS) Mogadishu Somalia Camel Research Center Mogadishu Somalia Department of Medicine Faculty of Veterinary Science Bangladesh Agricultural University Mymensingh Bangladesh

The study took a comprehensive approach to understanding mastitis in lactating camels, a disease that significantly impacts milk quantity and quality. This complex and multifactorial disease poses a significant challenge to dairy camel farming, particularly in Somalia. The studys objective was to determine the prevalence of mastitis and the risk factors associated with it among lactating camels on dairy farms in Benadir, Somalia. To achieve this, a cross-sectional study was conducted from May to September 2022 in the Benadir region of Somalia. A total of 96 lactating camels underwent examination using the California Mastitis Test (CMT) to identify clinical and subclinical mastitis cases. Additionally, a questionnaire survey was conducted among 20 farm employees/owners to gather information on hygiene practices, parity, lactation stage, tick infestation, and the presence of udder/teat lesions. Data regarding parity and lactation stage were obtained through owner interviews. The data collected on specifically designed forms were recorded and entered into a Microsoft Excel spreadsheet for analysis using SPSS version 20 statistical software, ensuring a comprehensive and reliable analysis of the data. The studys findings revealed a significant prevalence of camel mastitis, with 34.4% (33/96) of lactating camels affected and clinical and subclinical cases constituting 5.2% and 29.2%, respectively. Quarter-level prevalence was 46.3%, with clinical and subclinical mastitis at 4.7% and 41.6%, respectively. The study also identified significant associations (P < 0.05) among risk factors such as stage of lactation, parity, and age, indicating a higher susceptibility to mastitis in older camels during early lactation compared to those in late lactation and younger camels. These findings underscore the crucial role of inadequate hygienic conditions on camel farms and udder tick infestations in driving the elevated prevalence of mastitis, highlighting the need for improved manage

关键词： Mastitis Camel Prevalence Risk Factors Somalia

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