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Toxoplasmosis among pregnant women:High seroprevalence and risk factors in Kinshasa,Democratic Republic of Congo

Asian Pacific Journal of Tropical Biomedicine 2014年第1期4卷 69-74页

作者： Doudou Yobi Renaud Piarroux Coralie L'Ollivier jacqueline franck Hypolite Situakibanza Hypolite Muhindo Patrick Mitashi Raquel Andreia Inocencio da Luz Marc Van Sprundel Marleen Boelaert Jean-Pierre Van Geertruyden Pascal Lutumba Kinshasa University Democratic Republic of Congo University Hospital of Timone University of Antwerp Institute of Tropical Medicine Institut National de Recherche Biomedicale KinshasaDemocratic Republic of Congo

Objective:To determine the seroprevalence of toxoplasmosis in pregnant women,as well as the proportion of acutely infected and risk factors in the Democratic Republic of ***:Thirty maternities in Kinshasa were randomly selected and women attending antenatal consultation were invited to *** were interviewed with a structured questionnaire about known risk factors(age,meat consumption,contact with soil,and presence of cat)and a venous blood sample was *** were analysed for total immunoglobulins(Ig)by VIDAS Toxo Competition using Enzyme Linked Fluorescent *** was determined by VIDIA Toxo IgM and IgG avidity by VIDAS Toxo IgG ***:A total of 781 women were *** age was 28 years old(IQR:8.S).And 627women(80.3%;95%CI:77.5-83.1)were found to be positive to total Ig and 17 out of 387(4.4%;95%CI:2.3-6.4)were positive to *** avidity was low for 2(11.8%)women,intermediate for 2(11.8%)and high for 13 women(76.4%).There was no statistically significant association between Toxoplasma gondii infection and any risk factors ***:In Kinshasa,toxoplasmosis endemicity is highly *** woman out of twenty five had a recent toxoplasmosis infection and 20%were not protected against primoinfection,indicating a need for measures to prevent and control toxoplasmosis during pregnancy.

关键词： Seroprevalence Toxoplasmosis Pregnant women Kinshasa

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