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Robotically assisted removal of pelvic splenosis fifty-six years after splenectomy: A case report

World Journal of Clinical Cases 2021年第12期9卷 2868-2873页

作者： Alessio Tognarelli Lorenzo Faggioni Anna Paola Erba Pinuccia Faviana jacopo durante Francesca Manassero Cesare Selli Department of Translational Research and New Technologies in Medicine and Surgery Section of UrologyUniversity of PisaPisa 56126Italy Department of Translational Research and New Technologies in Medicine and Surgery Section of Diagnostic and Interventional RadiologyUniversity of PisaPisa 56126Italy Department of Translational Research and New Technologies in Medicine and Surgery Section of Nuclear MedicineUniversity of PisaPisa 56126ItalyPisa 56126Italy Department of Surgical Medical and Molecular Pathology and Critical AreaSection of PathologyUniversity of PisaPisa 56126Italy

BACKGROUND‘Splenosis’is defined as the autotransplantation of splenic tissue following trauma or surgery,usually in the form of intraperitoneal *** proliferation of imaging techniques has resulted in increased unexpected discoveries of splenosis nodules,and achieving a differential diagnosis can be *** medicine studies have been playing an increasingly important role in this process,but the clinical significance of asymptomatic nodules remains *** SUMMARY We present a case of pelvic splenosis in a 73-year-old man diagnosed 56 years after a splenectomy during a computed tomography(CT)follow-up for B-cell lymphoma,presenting intense contrast enhancement of an 18 mm nodule in the right recto-vesical space.18F-fluorodeoxyglucose demonstrated weak metabolic *** histological diagnosis was deemed necessary,the nodule was easily removed with robotically assisted laparoscopy,together with another 6 mm left a paracolic *** latter was previously undiagnosed but retrospectively visible on the CT *** In a patient requiring differential diagnosis of splenosis nodules from lymphomarecurrence, the robotic approach provided a safe en bloc removal with shorthospitalization. The Da Vinci Xi robot was particularly helpful because its opticscan be introduced from all ports, facilitating visualization and lysis of multipleintra-abdominal adhesions.

关键词： Pelvic splenosis Computed tomography Nuclear medicine Robotically assisted laparoscopy Da Vinci Xi Case report

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Don’t forget emergency surgery! Lessons to learn from elective indocyanine green-guided gastrointestinal interventions

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World Journal of Gastrointestinal Surgery 2024年第2期16卷 270-275页

作者： Davina Perini jacopo Martellucci Department of Emergency Emergency and Minimally Invasive Surgery UnitCareggi University HospitalFirenze 50041Italy

Fluorescence-based imaging has found application in several fields of elective surgery,but there is still a lack of evidence in the literature about its use in the emergency *** trials have consistently shown that indocyanine green(ICG)-guided surgery can dramatically reduce the risk of postoperative complic-ations,length of in-hospital stay and total healthcare costs in the elective *** is well-known that emergency surgery has a higher complication rate than its elective counterpart,therefore an impelling need for research studies to explore,validate and develop this issue has been *** present editorial aims to provide a critical overview of currently available applications and pitfalls of ICG fluorescence in abdominal ***,we evidenced how the experience of ICG-fluorescence in elective surgery might be of great help in implementing its use in acute *** the first paragraph we analyzed the tips and tricks of ICG-guided cancer surgery that might be exploited in acute *** then deepened the two most described topics in ICG-guided emergency surgery:Acute cholecystitis and intestinal ischemia,focusing on both the advantages and limitations of green-fluorescence application in these two *** emergency situations,ICG fluorescence demonstrates a promising role in preventing undue intestinal resections or their entity,facilitating the detection of intestinal ischemic zones,identifying biliary tree anatomy,reducing post-operative complications,and mitigating high mortality *** need to improve its application still exists,therefore we strongly believe that the elective and routinary use of the dye is the best way to acquire the necessary skills for emer-gency procedures.

关键词： Indocyanine green Fluorescence Navigation surgery Angiography Emergency surgery Decision-making

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Intraoperative cholangio-ultrasonography(IOCUS)during hepatectomy with resection of the biliary confluence:An effective alternative to intraoperative cholangiography

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Hepatobiliary & Pancreatic Diseases International 2024年第4期23卷 417-420页

作者： Daniele Del Fabbro Fabio Procopio jacopo Galvanin Guido Costa Simone Famularo Angela Palmisano Matteo Donadon Guido Torzilli Division of Hepatobiliary Surgery Department of SurgeryIRCCS Humanitas Research HospitalVia A.Manzoni 56Rozzano 20089MilanItaly Department of Biomedical Sciences Humanitas UniversityVia Rita Levi Montalcini 4Pieve Emanuele 20072MilanItaly

Intraoperative ultrasonography(IOUS)in hepatobiliary surgery is well known as an essential tool for radical and safe hepatectomies,allowing to perform parenchymal sparing surgery and,as consequence,to expand the surgical indications for patients otherwise considered ***,since many years,despite its effectiveness in the study of vascular anatomy of the liver,the gold standard for the assessment of biliary anatomy during surgery is intraoperative cholangiography(IOC),which is used for the validation of preoperative imaging as well as for guiding reconstruction in case of bile duct injury or resection.

关键词： anatomy biliary ultrasonography

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Long COVID and gut candidiasis:What is the existing relationship?

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World Journal of Gastroenterology 2024年第37期30卷 4104-4114页

作者： Filippo Bistagnino Davide Pizzi Filippo Mantovani jacopo Rosso Antonino Marcos Roberto Tovani-Palone Department of Medical Biotechnology and Translational Medicine International Medical SchoolUniversitàdegli Studi di MilanoMilan 20054Italy Department of Biomedical Sciences for Health Universitàdegli Studi di MilanoMilan 20133Italy Department of Research Analytics Saveetha Dental College and HospitalsSaveetha Institute of Medical and Technical SciencesChennai 600077India

Since the beginning of the coronavirus disease(COVID)2019 pandemic,thou-sands of articles on the topic have been published,and although there is a growing trend of research on another associated condition,long coronavirus disease,important points still remain to be clarified in this *** evidence has suggested a relevant link between new clinical discoveries and molecular mechanisms that could be associated with the manifestations of different signs and symptoms involving cases of long ***,one of the existing gaps that requires further investigation concerns a possible rela-tionship between gut candidiasis and long *** recent studies also suggest an interplay between the occurrence of these two conditions,it is not yet fully clear how this may happen,as well as the specifics regarding the possible pathophysiological mechanisms *** this connection and with the advent of a potential strengthening of the body of evidence supporting the hypothesis of a link between gut candidiasis and long COVID,a better understanding of the clinical presentation,pathophysiology and clinical management of such a relationship should be essential and useful for both,additional advances towards more targeted research and appropriate case *** more about the signs,symptoms,and complications associated with cases of long COVID is essential in order to more effectively mitigate the related burden and provide a higher quality of care and life for the affected *** light of this and the need for better outcomes,here we review and discuss the content on different aspects of long COVID,including its pathophysiology and the existing evidence of a potential relationship between such a condition and gut candidiasis,as well as suggest propositions for future related *** Long coronavirus disease(COVID)is a condition characterized by the emergence of new symptoms or the persistence of existing symptoms for at least two months,

关键词： Post-acute COVID-19 syndrome COVID-19 Candidiasis Gastrointestinal microbiome Pandemics

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Respiratory protein-driven selectivity during the Permian-Triassic mass extinction

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The Innovation 2024年第3期5卷 122-128页

作者： Haijun Song Yuyang Wu Xu Dai jacopo Dal Corso Fengyu Wang Yan Feng Daoliang Chu Li Tian Huyue Song William JFoster State Key Laboratory of Biogeology and Environmental Geology School of Earth SciencesChina University of GeosciencesWuhan 430074China Biogéosciences UMR 6282CNRSUniversitéde Bourgogne21000 DijonFrance Universitat Hamburg Institute for Geology20148 HamburgGermany

Extinction selectivity determines the direction of macroevolution,especially during mass extinction;however,its driving mechanisms remain poorly *** investigating the physiological selectivity of marine animals during the Permian-Triassic mass extinction,we found that marine clades with lower O2-carrying capacity hemerythrin proteins and those relying on O2 diffusion experienced significantly greater extinction intensity and body-size reduction than those with higher O2-carrying capacity hemoglobin or hemocyanin *** findings suggest that animals with high O2-carrying capacity obtained the necessary O2 even under hypoxia and compensated for the increased energy requirements caused by ocean acidification,which enabled their survival during the Permian-Triassic mass ***,high O2-carrying capacity may have been crucial for the transition from the Paleozoic to the Modern Evolutionary Fauna.

关键词： extinction selectivity finding

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Beyond total mesorectal excision: The emerging role of minimally invasive surgery for locally advanced rectal cancer

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World Journal of Gastrointestinal Surgery 2024年第8期16卷 2382-2385页

作者： Davina Perini Francesca Cammelli Maximilian Scheiterle jacopo Martellucci Annamaria Di Bella Carlo Bergamini Paolo Prosperi Alessio Giordano Department of Emergency and Acceptance Emergency Surgery UnitCareggi University HospitalFirenze 50137Italy

Multivisceral resection and/or pelvic exenteration represents the only potential curative treatment for locally advanced rectal cancer(LARC);however,it poses significant technical challenges,which account for the high risk of morbidity and mortality associated with the *** complete histopathologic resection is the most important determinant of patient outcomes,LARC often requires an extended resection beyond the total mesorectal excision plane to obtain clear re-section *** an era when laparoscopic surgery and robot-assisted surgery are becoming commonplace,the optimal approach to extensive pelvic inter-ventions remains ***,acceptance of the suitability of mini-mally invasive surgery is slowly gaining ***,there is still a lack of evidence in the literature about minimally invasive approaches in multiple and extensive surgical resections,highlighting the need for research studies to explore,validate,and develop this *** editorial aims to provide a critical overview of the currently available applications and challenges of minimally invasive abdo-minopelvic surgery for ***,we discuss recent developments in the field of robotic surgery for LARC,with a specific focus on new innovations and emerging frontiers.

关键词： Robotic surgery Pelvic exenteration Multivisceral resection Rectal cancer Total mesorectal excision

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贵州青岩中三叠世安尼期琥珀及其意义

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地球科学 2024年第4期49卷 1515-1523页

作者：田垚铠楚道亮曹怡然 jacopo Dal Corso Guido Roghi 宋海军田力刘传远贺箫缪雪张世岩舒文超童金南中国地质大学生物地质与环境地质国家重点实验室地球科学学院湖北武汉430074 国家研究委员会地球科学与地质资源研究所意大利帕多瓦351313 贵州地质博物馆贵州贵阳550081

中-晚三叠世是现代型生态系统构建的关键时期,系统研究该时期生物与环境的协同演变过程对揭示生物复苏机制和生态系统重建规律具有重要意义.琥珀是探讨中-晚三叠世植物演化和古气候演变的重要载体.对青岩剖面雷打坡段的琥珀和伴生的植... 详细信息

中-晚三叠世是现代型生态系统构建的关键时期,系统研究该时期生物与环境的协同演变过程对揭示生物复苏机制和生态系统重建规律具有重要意义.琥珀是探讨中-晚三叠世植物演化和古气候演变的重要载体.对青岩剖面雷打坡段的琥珀和伴生的植物化石开展研究,并将全球的中-晚三叠世琥珀的分布与湿润事件进行对比分析.结果发现青岩琥珀是由松柏类植物伏脂杉生产,琥珀的出现与松柏类植物的辐射演化有关.菊石生物地层表明含有琥珀的地层属于中三叠世安尼期Pelsonian亚期.认为琥珀的产出与湿润事件具有对应性,说明湿润事件可能是中-晚三叠世琥珀频繁出现的重要原因.

关键词：中三叠世安尼期琥珀湿润事件贵州青岩地层学

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Fat management in upper blepharoplasty:Addition or subtraction blepharoplasties,how and when

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World Journal of Clinical Cases 2024年第16期12卷 2796-2802页

作者： Giovanni Miotti jacopo Di Filippo Martina Grando Carlo Salati Pier Camillo Parodi Leopoldo Spadea Caterina Gagliano Mutali Musa Marco Zeppieri Department of Plastic Surgery University Hospital of UdineUdine 33100Italy Department of Internal Medicine Azienda Sanitaria Friuli OccidentaleSan Vito al Tagliamento 33078Italy Department of Ophthalmology University Hospital of UdineUdine 33100Italy Eye Clinic Policlinico Umberto I"Sapienza"University of RomeRome 00142Italy Department of Medicine and Surgery University of Enna"Kore"Enna 94100Italy Eye Clinic Catania University San Marco HospitalCatania 95121Italy Department of Optometry University of BeninBenin 3000283Nigeria Department of Ophthalmology Centre for Sight AfricaNkporOnitsha 434112Niger

BACKGROUND As one of the most common aesthetic surgical procedures carried out today,blepharoplasty should be in the repertoire of every plastic *** term blepharoplasty encompasses a wide range of techniques and options that must be tailored to the specific defect and patient one has to treat.A sound knowledge of the upper and lower eyelids’anatomy is essential for proper surgical *** have shifted towards more conservative methods(especially of the fat compartment)and sometimes in combination with augmentation techniques,helping to reach a rejuvenated *** To present an overview of the surgical techniques considered for upper lid blepharoplasty and fat pad management,in addition to information on how a surgeon may approach the best treatment for his patient based on current publications in *** We searched the literature published between 2013,to 2023 using Medline and Reference Citation *** database was searched using the keywords“upper blepharoplasty”AND“fat”.Papers without full text/abstracts and reviews were *** search strategy followed the *** American Society of Plastic Surgeons guidelines for Therapeutic Studies checklist was used to assess all *** authors individually reviewed each article and rated them for importance and relevance to the topic.A consensus was sought and the most relevant *** After the application of the selection criteria used in our review,13 publications were found to address upper lid blepharoplasty *** of these studies were reviews and three were retrospective *** publications were comparative studies and a further two were clinical *** The tendency of modern surgery is to be conservative,by removing adipose tissue only if strictly necessary and restoring the volume of the upper eyelid in a concept of beauty that espouses a"full"*** is no gold standard technique to achieve younger and enhanced eyelids

关键词： Blepharoplasty Fat pads Eye lid surgery Cosmetic aesthetic surgery Rejuvenation Plastic surgery

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Fusobacterium is toxic for head and neck squamous cell carcinoma and its presence may determine a better prognosis

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Cancer Communications 2024年第8期44卷 879-883页

作者： Anjali Chander jacopo Iacovacci Aize Pellon Radhika Kataria Anita Grigoriadis John Maher Cynthia Sears Gilad Bachrach Teresa Guerrero Urbano Mary Lei Imran Petkar Anthony Kong Tony Ng Ester Orlandi Nicola Alessandro Iacovelli Loris De Cecco Mara Serena Serafini David Moyes Tiziana Rancati Miguel Reis Ferreira Centre for Host-Microbiome Interactions King’s College LondonLondonUK Comprehensive Cancer Centre King’s College LondonLondonUK Department of Oncology Guys and St Thomas NHS Foundation TrustLondonUK Data Science Unit Fondazione IRCCS Istituto Nazionale dei TumoriMilanItaly Medicine Department Johns Hopkins University School of MedicineBaltimoreMarylandUSA Institute of Biomedical and Oral Research The Hebrew University-Hadassah School of Dental MedicineHadassah Ein Kerem CampusJerusalemIsrael Dipartimento di scienze Clinico-Chirurgiche Diagnostiche e PediatricheUniversitàdegli studi di PaviaPaviaItaly Radiation Oncology Department Fondazione IRCCS Istituto Nazionale dei TumoriMilanItaly Department of Medicine Weill Cornell MedicineNew YorkUSA

Head and neck squamous cell carcinoma(HNSCC)is a devastating *** morbid treatment,5-year survival rates remain poor(28%-67%)[1].There is a significant knowledge gap regarding how the microbiota may impact HNSCC treatment efficacy[2].We used microbiome data from two independent cohorts to test and validate the hypothesis that oral bacteria are associated with HNSCC prognosis and in vitro models to investigate mechanistic *** are detailed in Supplementary Materials.

关键词： prognosis squamous carcinoma

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Embeddings of Spherical Homogeneous Spaces

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Acta Mathematica Sinica,English Series 2018年第3期34卷 299-340页

作者： jacopo GANDINI Scuola Normale Superiore

We review in these notes the theory of equivariant embeddings of spherical homogeneous spaces. Given a spherical homogeneous space G/H, the normal equivariant embeddings of G/H are classified by combinatorial objects called colored fans, which generalize the fans appearing in the classification of toric varieties and which encode several geometric properties of the corresponding variety.

关键词： Spherical varieties homogeneous spaces

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