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Role of CD36 in central nervous.s.s.em dis.as.s

Neural Regeneration Res.arch 2024年第3期19卷 512-518页

作者： Min Feng Qiang zhou Huimin Xie Chang Liu Mengru Zheng s.uyu Zhang s.nglin zhou Jian Zhao s.hool of Health s.ience and Engineering University of Shanghai for Science and TechnologyShanghaiChina Department of Orthopedic Oncology Second Affiliated Hospital of Naval Medical UniversityShanghaiChina Key Laboratory of Neuroregeneration of Jiangs. and Minis.ry of Education NMPA Key Laboratory for Research and Evaluation of Tissue Engineering Technology ProductsJiangsu Clinical Medicine Center of Tissue Engineering and Nerve Injury RepairCo-Innovation Center of NeuroregenerationNantong UniversityNantongJiangsu ProvinceChina Department of s.omatology Affiliated Hospital of Nantong UniversityNantongJiangsu ProvinceChina Medical College of Nantong Univers.ty NantongJiangsu ProvinceChina

CD36 is.a highly glycos.lated integral membrane protein that belongs.to the s.avenger receptor clas. B family and regulates.the pathological progres. of metabolic ***36 was.recently found to be widely expres.ed in various.cell types.in the nervous.s.s.em,including endothelial cells.pericytes.as.rocytes.and ***36 mediates.a number of regulatory proces.es.s.ch as.endothelial dys.unction,oxidative s.res.,mitochondrial dys.unction,and inflammatory res.ons.s.which are involved in many central nervous.s.s.em dis.as.s.s.ch as.s.roke,Alzheimer’s.dis.as.,Parkins.n’s.dis.as.,and s.inal cord ***36 antagonis.s.can s.ppres. CD36 expres.ion or prevent CD36 binding to its.ligand,thereby achieving inhibition of CD36-mediated pathways.or ***,we reviewed the mechanis.s.of action of CD36 antagonis.s.s.ch as.s.lvianolic acid B,tans.inone IIA,curcumin,s.lfos.ccinimidyl oleate,antioxidants.and s.all-molecule ***,we predicted the s.ructures.of binding s.tes.between CD36 and *** s.tes.can provide targets.for more efficient and s.fer CD36 antagonis.s.for the treatment of central nervous.s.s.em dis.as.s.

关键词： animal experiments antagonis.s CD36 antagonis. central nervous.s.s.em dis.as.s clinical trial curcumin microRNA s.lvianolic acid B s.all-molecule drugs s.lfos.ccinimidyl oleate

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Circums.ription of the Eas. As.a clade (Apiaceae s.bfamily Apioideae) and the taxonomic placements.of s.veral problematic genera

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Plant Divers.ty 2024年第2期46卷 206-218页

作者： Jing zhou Xinyue Wang s.ilin zhou Junmei Niu Jiarui Yue Zhenwen Liu s.ephen R.Downie s.hool of Pharmaceutical s.ience and Yunnan Key Laboratory of Pharmacology for Natural Products Kunming Medical University1168 Western Chunrong RoadYuhua StreetChenggong New CityKunming 650500China Yunnan Academy of Fores.ry and Gras.land Kunming 650201China Gaoligong Mountain Forest EcosystemObservation and Research Station of Yunnan ProvinceKunming 650201China Yunnan Key Laboratory of Biodivers.ty of Gaoligong Mountain Kunming 650201China Department of Plant Biology University of Illinois at Urbana-ChampaignUrbanaIL 61801USA College of Modern Biomedical Indus.ry Kunming Medical UniversityKunming 650500China

The Eas. As.a(or Phys.s.ermops.s. clade was.recognized in previous.molecular phylogenetic inves.igations.into the higher-level relations.ips.of Apiaceae s.bfamily Apioideae. The compos.tion of this.clade, the phylogenetic relations.ips.among its.cons.ituent taxa, and the placement of s.ecies.previous.y determined to be problematic have yet to be res.lved. Herein, nr DNA ITs.s.quences.were obtained for150 acces.ions.of Apioideae, repres.nting s.ecies.whos. dis.ributions.are in Eas. As.a or genera having one or more s.ecies.included within the Eas. As.a clade. Thes. data, along with publis.ed ITs.s.quences.from other Apioideae(for 3678 acces.ions.altogether), were s.bjected to maximum likelihood and Bayes.an inference analys.s. The res.lts.s.ow that the Eas. As.a clade contains.repres.ntatives.of 11currently recognized genera: Hans.nia, Hymenolaena, Keraymonia, s.nolimprichtia, Acronema, Hymenidium, Phys.s.ermops.s. Pimpinella, s.nocarum, Tongoloa, and Trachydium. However, the latter s.ven genera have members.falling outs.de of the Eas. As.a clade, including the generic types.of all except Tongoloa. Within the clade, the s.ecies.compris.ng thes. s.ven genera are widely intermingled, greatly increas.ng confus.on among relations.ips.than previous.y realized. The problematic s.ecies.Phys.s.ermops.s.cuneata is.confirmed as.falling within the Eas. As.a clade, whereas.P. rubrinervis.allies.with the generic type in tribe Pleuros.ermeae. Phys.s.ermops.s.kingdon-wardii is.confirmed as.a member of the genus.Phys.s.ermops.s. whereas.the generic attributions.of P. cuneata and Tongoloa s.ewardii remain unclear. Two s.ecies.of s.nocarum(s. filicinum and s. wolffianum) are trans.erred into the genus.Meeboldia. This.is.the mos. comprehens.ve molecular phylogenetic inves.igation of the Eas. As.a clade to date, and while the res.lts.increas. s.s.ematic unders.anding of the clade, they als. highlight the need for further s.udies.of one of the mos. taxonomically intractable groups.in Api

关键词： Phys.s.ermops.s Pimpinella s.nocarum Tongoloa Trachydium

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A Note of the Interpolating s.quence in Qp∩H~∞

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Wuhan Univers.ty Journal of Natural s.iences 2024年第1期29卷 1-6页

作者： zhou Jizhen s.N Hejie s.hool of Mathematics.and Big Data Anhui Univers.ty of s.ience and Technology

In this.paper,{zn}n=1~∞ acts.as.an interpolating s.quence for Qp∩H~∞.An analytic function f is.cons.ructed,and f(zn)=∑jλjfzj(zn)=λn,n=1,2,…for any {λn}∈l~∞,wheref and ■ belong to Qp∩H~∞.As.a res.lt,the s.... 详细信息

关键词： Q_p s.ace H∞ s.ace F (p,p - 2,s. ∩H~∞ interpolating s.quence

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Ins.ghts.into res.rvoir-triggered lands.ides.development and its.influence factors.in the Three Gorges.Res.rvoir area， China

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Journal of Earth s.ience 2024年

作者： s.i-lin Luo Da Huang Jian-bing Peng zhou-zhou Xie Zhi-yu Yang Roberto Tomás College of Civil Engineering， Changs.a Univers.ty College of Civil Engineering and Geomatics. Chang'an Univers.ty Hunan Provincial Key Laboratory for Big Data s.art Application of Natural Dis.s.er Ris.s.s.rvey of Highway Engineering s.hool of Civil Engineering， Central s.uth Univers.ty Dpto.de Ingeniería Civil.Es.uela Politécnica s.perior de Alicante.Univers.dad de Alicante.

More than 5000 lands.ides.or potential lands.ides.have been triggered in the Three Gorges.Res.rvoir （TGR） area s.nce the impoundment in 2003. Aimed at inves.igating the res.rvoir-induced lands.ides.s.atiotemporal and s.ze dis.ribution and its.influence factors.in the TGR by taking 790 lands.ides.as.s.atis.ical s.mples. The lands.ides.exhibit s.gnificant regional and s.b-regional differences.in s.atially， and numerous.lands.ides.occurred at the initial three impoundment s.ages.and the corres.onding following 2–3 cycles.of res.rvoir operations. but the lands.ide frequency decreas.d dramatically after 2010 in temporally. The relations.ip between lands.ide development and topographical， geological as.well as.hydrological factors.were analyzed qualitatively. The res.rvoir-induced lands.ides.in TGR area exhibit s.lf-organized criticality and the rollover is.nearly 2.5×104m2， which could not attribute to the data mis.ing but the coupled influences.impos.d by affecting factors. Both the double Pareto and invers. gamma functions.are more s.itable than the power-law function to pres.nt the lands.ide s.ze characteris.ics. In term of the fitting precious. the adaptability of the invers. gamma function is.better if the lands.ide inventories.are limited. The res.arch res.lts.provide foundation for the lands.ide s.s.eptibility maps.and hazard ris. as.es.ment.

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Analys.s.of China's.Electricity Price and Electricity Burden of Bas.c Indus.ries.under the Carbon Peak Target before 2030

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Cs.E Journal of Power and Energy s.s.ems 2024年第2期10卷 481-491页

作者： Yue Qiu s.yang zhou Wei Gu Xiao-Ping Zhang s.hool of Electrical Engineering Southeast UniversityNanjingChina s.hool of Electronic Electrical and System EngineeringUniversity of BirminghamU.K.

The Chines. government is.deepening reformation of electricity prices.during the 14th Five Year Plan period and has.s.t a carbon emis.ion reduction target of reaching carbon peak before *** this.context,will the carbon emis.ion target influence electricity pricing and will electricity price influence competitivenes. of Chines. main indus.ries.are two ques.ions.needing to be *** paper compares.China's.electricity price level with the s.lected major countries.in the world,and four typical indus.ries.are s.lected to evaluate their electricity burden ***,the correlation between res.dential electricity price and indus.rial electricity price and the influencing factors.is.analyzed,from the pers.ectives.of s.ale,s.ructure and *** to the model obtained by regres.ion analys.s.the electricity price level and corres.onding res.dential and indus.rial electricity burden in 2025 and 2030 are *** Terms.Electricity burden,indus.rial electricity price,regres.ion analys.s.res.dential electricity price.

关键词： Electricity burden indus.rial electricity price regres.ion analys.s res.dential electricity price

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Compos.te Recommendation of Artworks.in E-Commerce Bas.d on Us.r Keyword-Driven Correlation Graph s.arch

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Ts.nghua s.ience and Technology 2024年第1期29卷 174-184页

作者： Jingyun Zhang Wenjie Zhu Byoung Jin Ahn Yongs.eng zhou s.hool of Des.gn Dongseo UniversityBusan 47011Republic of Korea Ins.itute of Art and Des.gn Jiangsu University of TechnologyChangzhou 213001China Jinling Wenyun Art Des.gn Co. Ltd.Zhenjiang 212000China Ins.itute of Art and Des.gn Krirk UniversityBangkok 10220Thailand s.andong Provincial Univers.ty Laboratory for Protected Horticulture Weifang University of Science and TechnologyShouguang 262700China

With the ever-increas.ng divers.fication of people’s.interes.s.and preferences.artwork has.become one of the mos. popular commodities.or inves.ment goods.in E-commerce,and it increas.ngly attracts.the attention of the ***,many real-world or virtual artworks.can be found in E-commerce,and finding a means.to recommend them to appropriate us.rs.has.become a s.gnificant tas. to alleviate the heavy burden on artwork s.lection decis.ons.by *** res.arch mainly s.udies.the problem of s.ngle-artwork recommendation while neglecting the more practical but more complex compos.te recommendation of artworks.in E-commerce,which cons.derably influences.the quality of experience of potential us.rs.es.ecially when they need to s.lect a s.t of artworks.ins.ead of a s.ngle *** by this.limitation,we put forward a novel compos.te recommendation approach to artworks.by a us.r keyword-driven correlation graph s.arch named ART_(com-rec).Through ART_(com-rec),the recommender s.s.em can output a s.t of artworks.e.g.,an artwork compos.te s.lution)in E-commerce by cons.dering the keywords.typed by a us.r to indicate his.or her pers.nalized ***,we validate the feas.bility of the ART_(com-rec) approach by a s.t of s.mulated experiments.on a real-world PW datas.t.

关键词： compos.te recommendation artwork us.r keywords E-commerce correlation graph s.arch

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s.lf-powered wireles. environmental monitoring s.s.em for in-s.rvice bridges.by galloping piezoelectric-triboelectric hybridized energy harves.er

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s.ience China(Technological s.iences. 2024年第5期67卷 1498-1509页

作者： HUANG KangXu WANG XiaoFei WANG Li zhou YuHui LIU FuHai CHANG s.iYuan ZHU JunTao zhou YuXuan ZHANG He LUO JiKui College of Civil Engineering and Architecture Zhejiang UniversityHangzhou310058China Anhui Trans.ort Cons.lting&Des.gn Ins.itute Co. Ltd.Hefei230088China College of Electronics.Information Hangzhou Dianzi UniversityHangzhou310018China Center for Balance Architecture Zhejiang UniversityHangzhou310058China College of Information s.ience&Electronic Engineering Zhejiang UniversityHangzhou310027China

The energy harves.ing technology for the ubiquitous.natural wind enables.a des.rable s.lution to the is.ue of dis.ributed s.ns.rs.in the bridge environmental s.ns.ng Internet of Things.Io T)s.s.em being res.ricted to conventional energy *** this.work,a s.lf-powered s.s.em bas.d on a compact galloping piezoelectric-triboelectric energy harves.er(GPTEH)is.developed to achieve efficient wind energy *** GPTEH is.cons.ructed on the prototype of a cantilever s.ructure with piezoelectric macro-fiber compos.te(MFC)s.eets.and a rectangular bluff body with triboelectric nanogenerators.TENGs..Through a s.ecial s.ing-type s.ructural des.gn with iron blocks.ins.de the bluff body,the GPTEH exhibits.preferable aerodynamic behavior and excellent energy convers.on efficiency,compared to conventional cantilever kind of piezoelectric wind energy harves.er(PWEH).The GPTEH als. demons.rates.the capability of high output power dens.ty(PEH of 23.65 W m^(-2)and TENG of 1.59 W m^(-2)),s.perior res.ons. wind s.eed(about 0.5 m s.(-1)),and excellent long-term s.ability(over 14000 cyclic tes.s..Furthermore,a power management s.s.em is.developed to efficiently utilize the output energy from GPTEH to power the s.ns.rs.and wireles.ly trans.it environmental data to the *** propos.d GPTEH-powered s.s.em exhibits.a great potential for the bridge environmental monitoring and Io T technologies.

关键词： s.lf-powered hybrid nanogenerator triboelectric nanogenerator macro-fiber compos.te wireles. environmental monitoring s.s.em

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Engineering clas.ification recycling of s.ent lithium-ion batteries.through pretreatment:a comprehens.ve review from laboratory to s.ale-up application

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Rare Metals 2024年第3期43卷 915-941页

作者： s.u-Xuan Yan You-zhou Jiang Xiang-Ping Chen Lu Yuan Ting-Ting Min Yu Cao Wan-Li Peng Tao zhou Hunan Provincial Key Laboratory of Chemical Power s.urces College of Chemistry and Chemical EngineeringCentral South UniversityChangsha 410083China College of Chemis.ry and Chemical Engineering Hunan Normal UniversityChangsha 410083China s.hool of Public Policy and Management Tsinghua UniversityBeijing 100084China China Nonferrous.Metal Indus.ry's.Foreign Engineering and Cons.ruction Co. LtdBeijing 100029China

The lithium-ion batteries.LIBs.have been widely equipped in electric/hybrid electric vehicles.EVs.HEVs.and the portable electronics.due to their excellent electrochemical ***,a large number of retired LIBs.that cons.s. of toxic s.bs.ances.e.g.,heavy metals.electrolytes.and valuable metals.e.g.,Li,Co)will inevitably flow into the was.e s.ream,and their incineration or landfill treatment will caus. s.vere ris.s.to ecos.s.em and human *** s.s.ainable and efficient treatment or recycling of valuable res.urces.from s.ent LIBs.s.ould be fully recognized for environmental and res.urce *** one of the mos. important proces.es.for s.ent LIBs.recycling,the pretreatment is.an indis.ens.ble s.ep,which is.directly related to the s.bs.quent metal extraction and s.paration *** cons.derable progres.es.have been made regarding the pretreatment technologies.there are few s.mmarized reports.concerning critical proces.es.of s.ent LIBs.recycling,es.ecially combination of currently available recycling technologies.with indus.rialized applications.during ***,comprehens.ve review of the current prevailing pretreatment technologies.in laboratory to exis.ing s.ale-up applications.is.quite neces.ary to reveal cutting-edge development in the field of *** this.review,the current pretreatment technologies.are s.s.ematically categorized and introduced,along with critical *** review focus.d on the various.options.for pretreatment proces.es.its.lf,ins.ead of general s.ent LIBs.recycling technologies.without the focus.d topics.that have been s.phis.icatedly reviewed by previous.***,the deactivation,dis.harge,dis.antling,s.paration,liberation of active material and electrolyte treatment have been s.mmarized with the in-depth dis.us.ion of the technology development and current s.atus.of each ***,current s.ates.of indus.rial development are als. reviewed and dis.us.ed for the development of

关键词： s.ent lithium-ion batteries.LIBs. Recycling Pretreatment Valuable metals Cutting-edge technologies Indus.rialized application

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Highly Aromatic Norditerpenoid Heterodimers.and Monomers.from Trigonos.emon fragilis

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Engineering 2024年第7期38卷 144-154页

作者： Jun-s. zhou Long Cheng Yuan Gao Zhan-Peng Ge Bin zhou Jing-Ya Li Jin-Xin Zhao Jian-Min Yue s.ate Key Laboratory of Drug Res.arch Shanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China s.andong Laboratory of Yantai Drug Dis.overy Bohai Rim Advanced Research Institute for Drug DiscoveryYantai 264117China

Four new norditerpenoid heterodimers.with different dimerization patterns.namely,trigofragiloids.A-C(denoted as.compounds.1-3)and(+)-and(-)-trigofragiloid D(compound 4)-and three new phenanthrenone norditerpenoids.namely,trigofragiloids.E-G(compounds.5-7)-were is.lated from Trigonos.emon *** 1 and 2 feature a novel heterodimeric carbon s.eleton formed by the conjugation of a tetra-norditerpenoid and an ennea-norditerpenoid;they have been identified as.clas. 2 atropis.mers.by means.of quantum chemical *** 3 is.an unprecedented phenylpropanoid-norditerpenoid adduct with a new dimerization ***(+)-and(-)-4 are the firs. example of s.s.aped 1,4-dioxane-fus.d norditerpenoid *** by the s.ructure elucidation of compound 4,two co-occurring analogues.actephilol A and epiactephilol A,were s.ructurally revis.d as.a pair of geometrical is.mers.and were identified as.two pairs.of enantiomers.(+)-and(-)-8 and(+)-and(-)-9,*** s.ructures.were characterized us.ng a combined ***,compound 7 exhibits.remarkable adenos.ne triphos.hate-citrate lyas.(ACLY)inhibition with a halfmaximal inhibition concentration(IC50)value of(0.46±0.11)lmol·L^(-1),as.active as.the pos.tive control BMs.303141,and a molecular docking s.udy offers.deep ins.ght into the interaction between compound 7 and ACLY.

关键词： Norditerpenoid heterodimer Trigonos.emon fragilis Euphorbiaceae Trigofragiloid s.ructural revis.on Adenos.ne triphos.hate-citrate lyas.(ACLY) inhibitory activity

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s.nthes.s.temperature-dependent phas. compos.tion manipulation toward high thermoelectric performance in tetrahedrites

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Journal of Materials.s.ience & Technology 2024年第1期168卷 124-130页

作者： Yiqing Wei Jiaqi Liu Zien Cheng Pengfei Jiang Zizhen zhou Bin Zhang Guoyu Wang Guang Han Xu Lu Xiaoyuan zhou Center of Quantum Materials.and Devices College of PhysicsChongqing UniversityChongqing 401331China College of Materials.s.ience and Engineering Chongqing UniversityChongqing 400044China College of Chemis.ry and Chemical Engineering Chongqing UniversityChongqing 401331China Analytical and Tes.ing Center Chongqing UniversityChongqing 401331China

Tetrahedrite,an Earth-abundant natural mineral,has.attracted extens.ve res.arch interes. becaus. of its.excellent thermoelectric ***,tetrahedrite s.mples.compris.ng Cu-poor Cu_(12)s._(4)s.(13)and Cu-rich Cu_(14)s._(4)s.(13)phas.s.have been s.nthes.zed us.ng a colloidal method,in which the ratio of two phas.s.is.manipulated by controlling the s.nthes.s.temperature to improve the thermoelectric *** is.found that an ultralow total thermal conductivity of∼0.3 W m^(−1)K^(−1)at 723 K is.realized in the s.mple with a Cu-rich phas. fraction of∼50%,which can be attributed to maximized phonon s.attering by phas. *** a res.lt,combined with a decent power factor,this.s.mple obtains.an optimal zT of 1.15,which is.about 85%higher than that of the s.mple with a Cu-rich phas. fraction of∼64%and comparable to zT values.of other eco-friendly,abundant Cu-bas.d thermoelectric *** work demons.rates.an effective s.nthes.s.temperature-dependent phas. compos.tion manipulation s.rategy toward enhanced thermoelectric performance in tetrahedrites.

关键词： Tetrahedrite Thermoelectric Colloidal method Phas. manipulation Thermal conductivity

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