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剑桥国际英语教程 [3版]

Treatment of dysplastic Barrett's Oesophagus in lower volume centres after structured training

2007年

作者： jack C. Richards, jonathan Hull, Susan Proctor[]

本书按照主题分类，单元练习分为话题性和功能性两类；每2个单元之后有一个复习单元；书的后一部分还有针对各个单元的交际活动和自学听力练习。

ISBN: (纸本)9787560062433

本书按照主题分类，单元练习分为话题性和功能性两类；每2个单元之后有一个复习单元；书的后一部分还有针对各个单元的交际活动和自学听力练习。

关键词：英语

来源：畅想之星图书光盘版（南... 畅想之星图书光盘版（南... 评论

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World Journal of Gastrointestinal Endoscopy 2015年第1期7卷 66-72页

作者： Georgina Chadwick jack Faulkner Robert Ley-Greaves Panagiotis Vlavianos Rob Goldin jonathan Hoare Department of Gastroenterology St Marys HospitalW2 1NY LondonUnited Kingdom Department of Histopathology St Marys HospitalW2 1NY LondonUnited Kingdom

AIM: To investigate whether dysplastic Barrett's Oesophagus can be safely and effectively treated endoscopically in low volume centres after structured training. METHODS: After attending a structured training program in Amsterdam on the endoscopic treatment of dysplastic Barrett's Oesophagus, treatment of these patients was initiated at St Marys Hospital. This is a retrospective case series conducted at a United Kingdom teaching Hospital, of patients referred for endoscopic treatment of Barrett's oesophagus with high grade dysplasia or early cancer, who were diagnosed between January 2008 and February 2012. Data was collected on treatment provided(radiofrequency ablation and endoscopic resection), and success of treatment both at the end of treatment and at follow up. Rates of immediate and long term complications were assessed. RESULTS: Thirty-two patients were referred to St Marys with high grade dysplasia or intramucosal cancer within a segment of Barrett's Oesophagus. Twentyseven met the study inclusion criteria, 16 of these had a visible nodule at initial endoscopy. Treatment was given over a median of 5 mo, and patients received a median of 3 treatment sessions over this time. At the end of treatment dysplasia was successfully eradicated in 96% and intestinal metaplasia in 88%, on per protocol analysis. Patients were followed up for a median of 18 mo. At which time complete eradication of dysplasia was maintained in 86%. Complications were rare: 2 patients suffered from post-procedural bleeding, 4 cases were complicated by oesophageal stenosis. Recurrence of cancer was seen in 1 case. CONCLUSION: With structured training good outcomes can be achieved in low volume centres treating dysplastic Barrett's Oesophagus.

关键词： Barrett's Oesophagus Oesophageal cancer Endoscopic treatment Radiofrequency ablation Endoscopic resection

Nanofiber matrix formulations for the delivery of Exendin-4 for tendon regeneration: In vitro and in vivo assessment

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Bioactive Materials 2023年第7期25卷 42-60页

作者： Sama Abdulmalik jack Gallo jonathan Nip Sara Katebifar Michael Arul Amir Lebaschi Lucas N.Munch Jenna M.Bartly Shilpa Choudhary Ivo Kalajzic Yeshavanth Kumar Banasavadi-Siddegowdae Syam P.Nukavarapu Sangamesh G.Kumbar Department of Orthopedic Surgery University of Connecticut HealthFarmingtonCTUSA Department of Biomedical Engineering University of ConnecticutStorrsCTUSA Department of Materials Science and Engineering University of ConnecticutStorrsCTUSA Department of Physiology and Neurobiology University of ConnecticutStorrsCTUSA Department of Immunology Center on AgingUniversity of Connecticut HealthFarmingtonCTUSA Department of Reconstructive Sciences University of Connecticut HealthFarmingtonCTUSA Surgical Neurology Branch National Institute of Neurological Disorders and StrokeNational Institutes of HealthBethesdaMDUSA

Tendon and ligament injuries are the most common musculoskeletal injuries,which not only impact the quality of life but result in a massive economic *** interventions for tendon/ligament injuries utilize biological and/or engineered grafts to reconstruct damaged tissue,but these have *** matrices confer superior physicochemical properties over biological grafts but lack desirable bioactivity to promote tissue *** incorporating drugs can enhance bioactivity,large matrix surface areas and hydrophobicity can lead to uncontrolled burst release and/or incomplete release due to *** overcome these limitations,we evaluated the delivery of a peptide growth factor(exendin-4;Ex-4)using an enhanced nanofiber matrix in a tendon injury *** overcome drug surface binding due to matrix hydrophobicity of poly(caprolactone)(PCL)-which would be expected to enhance cell-material interactions-we blended PCL and cellulose acetate(CA)and electrospun nanofiber matrices with fiber diameters ranging from 600 to 1000 *** avoid burst release and protect the drug,we encapsulated Ex-4 in the open lumen of halloysite nanotubes(HNTs),sealed the HNT tube endings with a polymer blend,and mixed Ex-4-loaded HNTs into the polymer mixture before *** reduced burst release from~75%to~40%,but did not alter matrix morphology,fiber diameter,or tensile *** evaluated the bioactivity of the Ex-4 nanofiber formulation by culturing human mesenchymal stem cells(hMSCs)on matrix surfaces for 21 days and measuring tenogenic differentiation,compared with nanofiber matrices in basal media ***,we observed that Ex-4 nanofiber matrices accelerated the hMSC proliferation rate and elevated levels of sulfated glycosaminoglycan,tendon-related genes(Scx,Mkx,and Tnmd),and ECM-related genes(Col-Ⅰ,Col-Ⅲ,and Dcn),compared to *** then assessed the safety and efficacy of Ex-4 nanofiber matrices in a full-thickness rat Achilles tendon

关键词： Nanofiber matrix formulation Protein delivery Soft tissue regeneration Halloysite nanotubes

New interchange English for international ***'s book-第2版 2

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2004年

作者： jack C. Richards jonathan Hull Susan Proctor

New interchange English for international ***'s edition:教师用书-第2版 2

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2005年

作者： jack C. Richards jonathan Hull Susan Proctor

本教材是目前国际上最有影响的综合性英语教材之一，专为非英语国家的学习者而设计，针对初级到高中级水平。本教材采用“交际教学法”，强调在实际交流中培养综合技能，尤其是语言的流利性、灵活性与精确性。既可作为主教材，也可作为... 详细信息

ISBN: (纸本)7560022162

本教材是目前国际上最有影响的综合性英语教材之一，专为非英语国家的学习者而设计，针对初级到高中级水平。本教材采用“交际教学法”，强调在实际交流中培养综合技能，尤其是语言的流利性、灵活性与精确性。既可作为主教材，也可作为视听说教材。

关键词：英语

Target Tracking and Classification Using Compressive Measurements of MWIR and LWIR Coded Aperture Cameras

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Journal of Signal and Information Processing 2019年第3期10卷 73-95页

作者： Chiman Kwan Bryan Chou jonathan Yang Akshay Rangamani Trac Tran jack Zhang Ralph Etienne-Cummings Applied Research LLC Rockville Maryland USA Google Inc. Mountain View California USA Department of Electrical and Computer Engineering the Johns Hopkins University Baltimore USA Department of Electrical Engineering Massachusetts Institute of Technology Cambridge Massachusetts USA

Pixel-wise Code Exposure (PCE) camera is one type of compressive sensing camera that has low power consumption and high compression ratio. Moreover, a PCE camera can control individual pixel exposure time that can enable high dynamic range. Conventional approaches of using PCE camera involve a time consuming and lossy process to reconstruct the original frames and then use those frames for target tracking and classification. In this paper, we present a deep learning approach that directly performs target tracking and classification in the compressive measurement domain without any frame reconstruction. Our approach has two parts: tracking and classification. The tracking has been done using YOLO (You Only Look Once) and the classification is achieved using Residual Network (ResNet). Extensive experiments using mid-wave infrared (MWIR) and long-wave infrared (LWIR) videos demonstrated the efficacy of our proposed approach.

关键词： Target Tracking Classification Compressive Sensing MWIR LWIR YOLO ResNet Infrared Videos

New interchange English for international communication

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2005年

作者： (美) jack C.Richards jonathan Hull Susan Proctor

本教材主要使用美国英语，但涉及许多国家、地区和文化，它强调在实际交流活动中培养语言，主要活动有主题讨论、语法结构、语言功能、词汇扩展和语言训练。

ISBN: (纸本)7560022049

关键词：英语

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Interchange

1990年

作者： richards jack C.

Biofabrication and biomanufacturing in Ireland and the UK

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Bio-Design and Manufacturing 2024年第6期7卷 825-856页

作者： jack F.Murphy Martha Lavelle Lisa Asciak Ross Burdis Hannah J.Levis Cosimo Ligorio Jamie Mc Guire Marlene Polleres Poppy O.Smith Lucinda Tullie Juan Uribe-Gomez Biqiong Chen jonathan I.Dawson Julien E.Gautrot Nigel M.Hooper Daniel J.Kelly Vivian S.W.Li Alvaro Mata Abhay Pandit James B.Phillips Wenmiao Shu Molly M.Stevens Rachel L.Williams James P.K.Armstrong Yan Yan Shery Huang Department of Engineering University of CambridgeCambridge CB21PZUK Department of Translational Health Sciences Bristol Medical SchoolUniversity of BristolBristol BS13NYUK Department of Biomedical Engineering University of StrathclydeGlasgow G40NWUK Department of Materials Institute of Biomedical EngineeringImperial College LondonLondon SW72AZUK Department of Bioengineering Institute of Biomedical EngineeringImperial College LondonLondon SW72AZUK Department of Eye and Vision Science Institute of Life Course and Medical SciencesUniversity of LiverpoolLiverpool L78TXUK Biodiscovery Institute University of NottinghamNottingham NG72RDUK Department of Chemical and Environmental Engineering University of NottinghamNottingham NG72RDUK Centre for Human Development Stem Cells and RegenerationHuman Development and HealthFaculty of MedicineUniversity of SouthamptonSouthampton S0166YDUK Division of Neuroscience School of Biological SciencesFaculty of BiologyMedicine and HealthUniversity of ManchesterManchester M139PTUK UCL Centre for Nerve Engineering Department of PharmacologyUCL School of PharmacyUniversity College LondonLondon WC1N 1AXUK Stem Cell and Cancer Biology Laboratory The Francis Crick InstituteLondon NW11ATUK CÚRAM SFI Research Centre for Medical DevicesUniversity of GalwayGalway H91 W2TYIreland School of Mechanical and Aerospace Engineering Queen’s University BelfastBelfast BT95AHUK School of Engineering and Materials Science Queen Mary University of LondonLondon E14NSUK Geoffrey Jefferson Brain Research Centre Manchester Academic Health Science CentreNorthern Care Alliance and University of ManchesterManchester M139PLUK Trinity Centre for Biomedical Engineering Trinity Biomedical Sciences InstituteTrinity College DublinDublin 2Ireland Department of Mechanical Manufacturing and Biomedical EngineeringSchool of EngineeringTrinity College DublinDublin 2Ireland Advanced Materials and Bioengineering Research Centre(AMBER) Royal College of Surgeons in Ireland and T

As we navigate the transition from the Fourth to the Fifth Industrial Revolution,the emerging fields of biomanufacturing and biofabrication are transforming life sciences and *** sectors are benefiting from a synergy of synthetic and engineering biology,sustainable manufacturing,and integrated design *** techniques such as 3D bioprinting,tissue engineering,directed assembly,and self-assembly are instrumental in creating biomimetic scaffolds,tissues,organoids,medical devices,and biohybrid *** field of biofabrication in the United Kingdom and Ireland is emerging as a pivotal force in bioscience and healthcare,propelled by cutting-edge research and *** on the production of biologically functional products for use in drug delivery,in vitro models,and tissue engineering,research institutions across these regions are dedicated to innovating healthcare solutions that adhere to ethical standards while prioritising sustainability,affordability,and healthcare system benefits.

关键词： Bioprinting Drug delivery Biomaterials Tissue engineering Sustainability Biohybrid