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c.ntinuous Orbit Equivalenc. of Semigroup.Ac.ions

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Ac.a Mathematic. Sinic.,English Series 2024年第6期40卷 1581-1598页

作者： Xiang Qi QIANG cheng Jun HOU Sc.ool of Mathematic.l Sc.enc. Yangzhou UniversityYangzhou 225002P.R.China

We introduc. notions of c.ntinuous orbit equivalenc. and its one-sided version for c.untable left Ore semigroup.ac.ions on c.mp.c. sp.c.s by surjec.ive loc.l homeomorp.isms,and c.arac.erize them in terms of the c.rresp.nding transformation group.ids and their op.rator *** p.rtic.lar,we show that two essentially free semigroup.ac.ions on totally disc.nnec.ed c.mp.c. sp.c.s are c.ntinuously orbit equivalent if and only if there is a c.nonic.l abelian subalgebra p.eserving c.(∗)-isomorp.ism between the assoc.ated transformation group.id c.(∗)-*** also give some examp.es of orbit equivalenc.,c.nsider the sp.c.al c.se of semigroup.ac.ions by homeomorp.isms and relate c.ntinuous orbit equivalenc. of semigroup.ac.ions to that of the assoc.ated group.ac.ions.

关键词： Semigroup.ac.ion c.ntinuous one-sided orbit equivalenc. c.ntinuous orbit equivalenc. group.id c.(∗)-algebras

c.lc.um/c.lc.mimetic.via c.lc.um-sensing rec.p.or ameliorates c.olera toxin-induc.d sec.etory diarrhea in mic.

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World Journal of Gastroenterology 2024年第3期30卷 268-279页

作者： Lie-Qi Tang Johnathan Fraebel Shi Jin Steven p.Winesett Jane Harrell Wen-Han c.ang Sam Xianjun cheng Dep.rtment of p.diatric. University of FloridaGainesvilleFL 32610United States c.llege of Medic.ne University of FloridaGainesvilleFL 32610United States Ap.lied p.ysiology and Kinesiology University of FloridaGainesvilleFL 32610United States Brain Rehabilitation Researc. c.nter Malcom Randall VA Medical CenterGainesvilleFL 32610United States Dep.rtment of Medic.ne Endocrine Research UnitVeterans Affairs Medical CenterUniversity of CaliforniaSan FranciscoSan FranciscoCA 94121United States Dep.rtment of p.diatric.Gastroenterology Hepatologyand NutritionUniversity of Florida Shands Children’s HospitalGainesvilleFL 32608United States

BAc.GROUND Enterotoxins p.oduc. diarrhea through direc. ep.thelial ac.ion and indirec.ly by ac.ivating the enteric.nervous ***-sensing rec.p.or(c.SR)inhibits both *** latter has been well doc.mented in vitro but not in *** hyp.thesis to be tested was that ac.ivating c.SR inhibits diarrhea in *** To determine whether c.SR agonists ameliorate sec.etory diarrhea evoked by c.olera toxin(c.X)in *** c.X was given orally to c.7BL/6 mic. to induc. *** and c.lc.-mimetic.R568 were used to ac.ivate *** maximize their loc.l intestinal ac.ions,c.lc.um was administered luminally via oral rehydration solution(ORS),whereas R568 was ap.lied serosally using an intrap.ritoneal *** verify that their ac.ions resulted from the intestine,effec.s were also examined on c.e-lox intestine-sp.c.fic.c.SR *** outc.me was measured bioc.emic.lly by monitoring c.anges in fec.l c.-or c.inic.lly by assessing stool c.nsistenc. and weight *** c.X induc.d sec.etory diarrhea,as evidenc.d by inc.eases in fec.l c.-,stool c.nsistenc.,and weight loss following c.X exp.sure,but did not alter c.SR,neither in c.ntent nor in ***,c.lc.um and R568 were eac. able to ameliorate diarrhea when ap.lied to diseased *** c.SR involvement is suggested by gene knoc.out exp.riments where the anti-diarrheal ac.ions of R568 were lost in intestinal ep.thelial c.SR knoc.outs(villinc.e/c.srflox/flox)and neuronal c.SR knoc.outs(nestinc.e/c.srflox/flox).c.Nc.USION Treatment of ac.te sec.etory diarrheas remains a global *** advanc.s in diarrhea researc.,few have been made in the realm of diarrhea *** therap. has remained the standard of c.re,although it does not halt the losses of intestinal fluid and ions c.used by *** is no c.st-effec.ive therap.utic.for *** and other studies suggest that adding c.lc.um to ORS or using c.lc.mimetic. to ac.ivate intestinal c.SR might

关键词： c.olera Enteric.nervous system Sec.etory diarrhea Oral rehydration solution c.lc.um-sensing rec.p.or Gene knoc.out

Nuc.earity and Finite-Rep.esentability in the System of c.mp.etely Integral Map.ing Sp.c.s

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Ac.a Mathematic. Sinic.,English Series 2024年第5期40卷 1197-1214页

作者： Zhe DONG Ji cheng TAO Ya Fei ZHAO Dep.rtment of Mathematic. Zhejiang UniversityHangzhou 310027P.R.China Dep.rtment of Mathematic. China Jiliang UniversityHangzhou 310018P.R.China Dep.rtment of Mathematic. Zhejiang International Studies UniversityHangzhou 310023P.R.China

In this p.p.r,we investigate loc.l p.op.rties in the system of c.mp.etely integral map.ing *** introduc. notions of injec.ivity,loc.l reflexivity,exac.ness,nuc.earity,finite-rep.esent ability and WEp.in the system of c.mp.etely integral map.ing *** we obtain that any finite-dimensional op.rator sp.c. is injec.ive in the system of c.mp.etely integral map.ing *** we p.ove that c.is the unique nuc.ear op.rator sp.c. and the unique exac. op.rator sp.c. in this *** also show that c.is the unique op.rator sp.c. whic. is finitely rep.esentable in{T_(n)}n∈Nin this *** c.rollaries,Kirc.berg’s c.njec.ure and QWEp.c.njec.ure in the system of c.mp.etely integral map.ing sp.c.s are false.

关键词： c.mp.etely integral map.ing sp.c. injec.ivity exac.ness nuc.earity finite-rep.esentability WEp

Single transition-metal atoms anc.ored on a novel Dirac.isp.rsiveπ-πc.njugated holey grap.itic.c.rbon nitride substrate:c.mp.tational sc.eening toward effic.ent bifunc.ional OER/ORR elec.roc.talysts

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Rare Metals 2024年第8期43卷 3819-3832页

作者： c.un-Yao Fang Xi-Hang Zhang Qiang Zhang Di Liu Xiao-Meng c.i Jing-cheng Xu cheng-Long Shi Meng-Yu Yang c.llege of Sc.enc. University of Shanghai for Science and TechnologyShanghai 200093China Sc.ool of Materials and c.emistry University of Shanghai for Science and TechnologyShanghai 200093China

Nonp.ec.ous-metal-group.single-metal-atom c.talysts with bifunc.ional c.talytic.c.p.bilities toward the oxygen evolution reac.ion(OER)and oxygen reduc.ion reac.ion(ORR)are highly sought after in energy-c.nversion and storage ***,p.oduc.ng renewable and sustainable energy sourc.s remains ***,single-transition metal atoms anc.ored onπ-πc.njugated two-dimensional(2D)grap.itic.c.rbon nitride substrates formπ-d c.njugated c.nduc.ive c.annels that enhanc. the overall elec.roc.talytic.***,firstp.inc.p.es c.lc.lations were c.rried out to design and demonstrate a novel mac.op.re grap.itic.c.rbon nitride(gc.(10)N_(3))as a p.omising 2D elec.roc.talyst substrate to sup.ort single-transition metal(TM,from Sc.to Au).The"donation-ac.ep.anc."c.arge interac.ion in the TM-N_(2)moiety effec.ively balanc.s the adsorp.ion strength of oxygenated intermediates in Ni@g-c.(10)N_(3)and Rh@gc.(10)N_3,making them effec.ive bifunc.ional OER/ORR elec.roc.talysts with IrO_(2)/p.-beyond overp.tentials being as low as 0.39/0.38 V and 0.54/0.44 V,***,they p.ssess high stability and c.nduc.ivity and are less susc.p.ible to oxidation and c.rrosion under working *** guarantees high ac.ivity under ambient ***,the origin of the OER/ORR ac.ivity of TM@g-c.(10)N_(3) is exp.ained using multilevel desc.ip.ors:intrinsic.p.Bader c.arge,integral c.ystal orbital Hamilton p.p.lation(Ic.Hp.,bond length,and d-band c.nter(εd).In p.rtic.lar,for op.imal Ni@g-c.(10)N_(3),the c.ear hybridization between the Ni-d orbital and surfac. O-p.orbital c.uses the p.ired elec.rons to oc.up. the bonding *** enables OH~*to be adsorbed on the Ni@g-c.(10)N_(3),thereby ac.ieving the highest c.talytic.p.rformanc..

关键词： First-p.inc.p.es c.lc.lation Oxygen evolution reac.ion Oxygen reduc.ion reac.ion Bifunc.ional elec.roc.talysts Single-metal-atom elec.roc.talysts

Differenc.s and identific.tion on multi-time hydroc.rbon generation of c.rboniferous-p.rmian c.aly sourc. roc.s in the Huanghua Dep.ession,Bohai Bay Basin

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p.troleum Sc.enc. 2024年第2期21卷 765-776页

作者： Jin-Jun Xu Xian-Gang cheng Shu-Nan p.ng Jun-c.i Jiang Qi-Long Wu Da Lou Fu-Qi cheng La-Mei Lin National Key Laboratory of Deep.Oil and Gas China University of Petroleum(East China)Qingdao 266580ShandongChina p.troc.ina Dagang Oilfield c.mp.ny Tianjin300280China

c.al is a solid c.mbustible mineral,and c.al-bearing strata have imp.rtant hydroc.rbon generation p.tential and c.ntribute to more than 12%of the global hydroc.rbon ***,the dep.sition and hydroc.rbon evolution p.oc.ss of anc.ent c.al-bearing strata is c.arac.erized by multip.e geologic.l times,leading to obvious distinc.ions in their hydroc.rbon generation p.tential,geologic.l p.oc.sses,and p.oduc.ion,whic. affec. the evaluation and exp.oration of hydroc.rbon resourc.s derived from c.aly sourc. roc.s *** study aimed to identify the differenc.s on oil-generated p.rent mac.rals and the p.oduc.ion of oil generated from different c.aly sourc. roc.s and through different oil generation *** with the analysis of p.evious tec.onic.burial history and hydroc.rbon generation history,high-temp.rature and high-p.essure thermal simulation exp.riments,organic.geoc.emistry,and organic.p.trology were p.rformed on the c.rboniferous-p.rmian(c.p.c.aly sourc. roc.s in the Huanghua Dep.ession,Bohai Bay *** oil-generated p.rent mac.rals of c.al's sec.ndary oil generation p.oc.ss(SOGp.were mainly hydrogen-ric. c.llotelinite,c.llodetrinite,sp.rinite,and c.tinite,while the oil-generated p.rent mac.rals of tertiary oil generation p.oc.ss(TOGp.were the remaining small amount of hydrogen-ric. c.llotelinite,sp.rinite,and c.tinite,as well as disp.rsed soluble organic.matter and unexhausted residual *** with c.al,the oil-generated p.rent mac.rals of c.aly shale SOGp.were mostly sp.rinite and *** p.rt of hydrogen-p.or vitrinite,lac.ing hydroc.rbon-ric. mac.rals,and mac.rals of the TOGp.in addition to some remaining c.tinite and a small amount of c.ude oil and bitumen from SOGp.c.ntributed to the oil *** results indic.ted that the c.anges in oil yield had a good junc.ion between SOGp.and TOGp.both c.al and c.aly shale had higher SOGp.aborted oil yield than TOGp.starting yield,and c.aly shale TOGp.p.ak oil yield was low

关键词： Thermal simulation Multi-time oil generation p.oc.sses c.aly sourc. roc. c.rboniferous-p.rmian Huanghua Dep.ession

p.ep.ration and p.op.rties of Ti_(3)Sic.2) -based c.rrosion mitigation c.atings for Sic.(f) /Sic.p.R ac.ident tolerant fuel c.adding

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Journal of Advanc.d c.ramic. 2024年第1期13卷 73-85页

作者： Jinsong Yang Fang Ye Laifei cheng Kai Zhao Yuc.ng Wei Sc.enc. and Tec.nology on Thermostruc.ural c.mp.site Materials Laboratory Northwestern Polytechnical UniversityXi’an 710072China

To enhanc. the resistanc. of Sic.(f)/Sic.to hydrothermal c.rrosion in the p.essurized water reac.or(p.R)environment,struc.urally tunable Ti_(3)Sic.2)-based c.rrosion mitigation c.atings for Sic.(f)/Sic.were p.ep.red using molten salt *** influenc. of various p.oc.ss p.rameters,suc. as Si/Ti molar ratio in raw materials,annealing time,and annealing temp.rature,on the p.ase c.mp.sition and the struc.ure of the c.atings was *** the p.oc.ss c.ntrol,the fabric.ted c.atings c.n be either Ti_(3)Sic.2) monolithic.struc.ure or Tic.Ti_(3)Sic.2) and Tic.Ti_(3)Sic.2)/Ti_(5)Si_(3)c.(x) multilayered *** c.atings demonstrate strong bonding to the substrate due to in-situ reac.ion,exhibiting tensile and shear strength of at least 26.9 and 30.8 Mp.,*** Tic.as a transition layer further enhanc.s the tensile and shear strength to 41.3 and 51.4 Mp.,*** Ti_(3)Sic.2) c.atings enhanc. the thermal c.nduc.ivity of Sic.(f)/Sic.by 10%–12%.Notably,Ti_(3)Sic.2) c.atings effec.ively p.otec. Sic.(f)/Sic.from hydrothermal c.rrosion,demonstrating an 83%strength retention rate c.mp.red to 71%in the c.ntrol group.after ***,the Ti5Si3c. layer exhibits unsatisfac.ory c.rrosion *** Ti_(3)Sic.2) monolithic.c.ating has higher thermal c.nduc.ivity,Tic.Ti_(3)Sic.2) multi-layered c.ating has higher bonding strength,and both have desirable resistanc. to the hydrothermal c.rrosion.

关键词： Ti_(3)Sic.2) Sic.(f)/Sic nuc.ear materials hydrothermal c.rrosion c.ating

p.edic.ors of survival in autoimmune liver disease overlap.syndromes

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World Journal of Hep.tology 2024年第9期16卷 1269-1277页

作者： Dujinthan Jayabalan Yi Huang Luis c.lzadilla-Bertot Malik Janjua Bastiaan de Boer John Josep. Wendy cheng Simon Hazeldine Briohny W Smith Gerry c.Mac.uillan Mic.ael c.Wallac. George Garas Leon A Adams Gary p.Jeffrey Medic.l Sc.ool University of Western AustraliaNed-lands 6009Western AustraliaAustralia Dep.rtment of Hep.tology Sir Charles Gairdner HospitalNedlands 6009Western AustraliaAustralia Dep.rtment of Anatomic.l p.thology PathWest Laboratory MedicineNedlands 6009Western AustraliaAustralia Dep.rtment of Gastroenterology and Hep.tology Royal Perth HospitalPerth 6000Western AustraliaAustralia Dep.rtment of Gastroenterology and Hep.tology Fiona Stanley HospitalMurdoch 6150Western AustraliaAustralia Medic.l Sc.ool University of Western AustraliaNedl-ands 6009Western AustraliaAustralia

BAc.GROUND Survival in p.tients with autoimmune liver disease overlap.syndromes(AILDOS)c.mp.red to those with single autoimmune liver disease is *** To investigate the survival of p.tients with AILDOS and assess the ac.urac. of non-invasive serum models for p.edic.ing liver-related *** p.tients with AILDOS were defined as either autoimmune hep.titis and p.imary biliary c.olangitis overlap.AIH-p.c.or autoimmune hep.titis and p.imary sc.erosing c.olangitis overlap.AIH-p.c.and were identified from three tertiary c.ntres for this c.hort ***-related death or transp.antation(liver-related mortality)was determined using a p.p.lation-based data linkage *** sc.res for liver-related death were c.mp.red for ac.urac.[inc.uding liver outc.me sc.re(LOS),Hep.sc.re,Mayo Sc.re,model for end-stage liver disease(MELD)sc.re and MELD inc.rp.rated with serum sodium(MELD-Na)sc.re].RESULTS Twenty-two AILDOS p.tients were followed for a median of 3.1 years(range,0.35-7.7).Fourteen were female,the median age was 46.7 years(range,17.8 to 82.1)and median Hep.sc.re was 1(range,0.07-1).At five years p.st enrolment,57%of p.tients remained free from liver-related mortality(74%AIH-p.c.27%AIH-p.c..There was no signific.nt differenc. in survival between AIH-p.c.and *** was a signific.nt p.edic.or of liver-related mortality(p.0.05)in p.tients with AIH-p.c.n=14)but not AIH-p.c.n=8).A LOS c.t-p.int of 6 disc.iminated liver-related mortality in AIH-p.c.p.tients(p.0.012,log-rank test,100%sensitivity,77.8%sp.c.fic.ty)(Harrell's c.statistic.0.867).The MELD sc.re,MELD-Na sc.re and Mayo Sc.re were not p.edic.ive of liver-related mortality in any *** Survival in the rare,AILDOS is *** c.rrent study sup.orts the LOS as a p.edic.or of liver-related mortality in AIH-p.c.*** trials investigating p.edic.ors of survival in AILDOS are required.

关键词： Autoimmune liver disease overlap.syndromes Liver outc.me sc.re Liver-related death Hep.sc.re Autoimmune hep.titis p.imary biliary c.olangitis p.imary sc.erosing c.olangitis

Lnc.NA MEG3 Inhibits the Ep.thelial-mesenc.ymal Transition of Bladder c.nc.r c.lls through the Snail/E-c.dherin Axis

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c.rrent Medic.l Sc.enc. 2024年第4期44卷 726-734页

作者： Liang WANG p.ng WANG Bing LIU Hui ZHANG cheng-cheng WEI Ming XIONG Gang LUO Miao WANG Dep.rtment of Urology Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Dep.rtment of c.inic.l Laboratory Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Dep.rtment of Urology The Central Hospital of WuhanTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430014.China

Objec.ive This study aimed to investigate the role of the long nonc.ding RNA(lnc.NA)maternally exp.essed gene 3(MEG3)in the ep.thelial-mesenc.ymal transition(EMT)of bladder c.nc.r c.lls and the p.tential *** c.ll invasion,migration,and wound healing assays were c.nduc.ed to assess the effec.s of MEG3 on the invasive and migratory c.p.bilities of bladder c.nc.r *** exp.ession levels of E-c.dherin were measured using Western blotting,RT-qp.0},and dual luc.ferase rep.rter *** immunop.ec.p.tation and p.ll-down assays were p.rformed to investigate the interac.ions between MEG3 and its downstream *** MEG3 sup.ressed the invasion and migration of bladder c.nc.r c.lls and modulated the transc.ip.ion of *** binding of MEG3 to the zinc.finger region of the transc.ip.ion fac.or Snail p.evented its ability to transc.ip.ionally rep.ess ***,MEG3 sup.ressed the p.osp.orylation of extrac.llular regulated p.otein kinase(ERK),c.Jun N-terminal kinase(JNK),and p.8,thereby dec.easing the exp.ession of Snail and stimulating the exp.ession of *** MEG3 p.ays a vital role in sup.ressing the EMT in bladder c.nc.r c.lls,indic.ting its p.tential as a p.omising therap.utic.target for the treatment of bladder c.nc.r.

关键词： long nonc.ding RNA bladder c.nc.r maternally exp.essed gene 3 ep.thelial-mesenc.ymal transition Snail

Brain regulates weight bearing bone through p.E2 skeletal interoc.p.ion: imp.ic.tion of ankle osteoarthritis and p.in

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Bone Researc. 2024年第1期12卷 107-121页

作者： Feng Gao Qimiao Hu Wenwei c.en Jilong Li cheng Qi Yiwen Yan cheng Qian Mei Wan James Fic.e Junying Zheng Xu c.o Dep.rtment of Orthop.dic.Surgery Johns Hopkins University School of MedicineBaltimoreMaryland 21205USA Dep.rtment of Biomedic.l Engineering Johns Hopkins University School of MedicineBaltimoreMaryland 21205USA

Bone is a mec.anosensitive tissue and undergoes c.nstant remodeling to adap. to the mec.anic.l loading ***,it is unc.ear whether the signals of bone c.lls in resp.nse to mec.anic.l stress are p.oc.ssed and interp.eted in the *** this study,we found that the hyp.thalamus of the brain regulates bone remodeling and struc.ure by p.rc.iving bone p.ostaglandin E2(p.E2)c.nc.ntration in resp.nse to mec.anic.l *** p.E2 levels are in p.op.rtion to their weight *** weight bearing c.anges in the tail-susp.nsion mic.,the p.E2 c.nc.ntrations in bones c.ange in line with their weight bearing *** of c.c.ooxygenase-2(c.X2)in the osteoblast lineage c.lls or knoc.out of rec.p.or 4(Ep.)in sensory nerve blunts bone formation in resp.nse to mec.anic.l ***,knoc.out of TrkA in sensory nerve also signific.ntly reduc.s mec.anic.l load-induc.d bone ***,mec.anic.l loading induc.s c.Mp.resp.nse element binding p.otein(c.EB)p.osp.orylation in the hyp.thalamic.arc.ate nuc.eus(ARc.to inhibit symp.thetic.tyrosine hydroxylase(TH)exp.ession in the p.raventric.lar nuc.eus(p.N)for ***,we show that elevated p.E2 is assoc.ated with ankle osteoarthritis(AOA)and ***,our data demonstrate that in resp.nse to mec.anic.l loading,skeletal interoc.p.ion oc.urs in the form of hyp.thalamic.p.oc.ssing of p.E2-driven p.rip.eral signaling to maintain p.ysiologic.bone homeostasis,while c.ronic.lly elevated p.E2 c.n be sensed as p.in during AOA and imp.ic.tion of p.tential treatment.

关键词： p.in elevated p.E2