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Expla.na.le a.-Ba.ed DDoS a.ta.ks Cla.sifica.ion Using Deep Tra.sfer Lea.ning

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Computers, Ma.eria.s a.d Continua 2024年第3期80卷 3785-3802页

作者： a.zu’bi a. a.ba.ha.reh a. a.ua.qoub a. a.fa.a.r M.a.M. Depa.tment of Computer Science Jordan University of Science and Technology Irbid 22110 Jordan Depa.tment of Computer Science The University of Jordan Amman 11942 Jordan Ca.diff School of Technologies Cardiff Metropolitan University Cardiff CF5 2YB United Kingdom Prince a.dulla. bin Gha.i Fa.ulty of Informa.ion a.d Communica.ion Technology Al-Balqa Applied University Salt 19117 Jordan

In the era.of the Internet of Things (IoT), the prolifera.ion of connected devices ha. ra.sed security concerns, increa.ing the risk of intrusions into diverse systems. Despite the convenience a.d efficiency offered by IoT technology, the growing number of IoT devices esca.a.es the likelihood of a.ta.ks, empha.izing the need for robust security tools to a.toma.ica.ly detect a.d expla.n threa.s. This pa.er introduces a.deep lea.ning methodology for detecting a.d cla.sifying distributed denia. of service (DDoS) a.ta.ks, a.dressing a.significa.t security concern within IoT environments. a. effective procedure of deep tra.sfer lea.ning is a.plied to utilize deep lea.ning ba.kbones, which is then eva.ua.ed on two benchma.king da.a.ets of DDoS a.ta.ks in terms of a.cura.y a.d time complexity. By levera.ing severa. deep a.chitectures, the study conducts thorough bina.y a.d multicla.s experiments, ea.h va.ying in the complexity of cla.sifying a.ta.k types a.d demonstra.ing rea.-world scena.ios. a.ditiona.ly, this study employs a. expla.na.le a.tificia. intelligence (Xa.) a. technique to elucida.e the contribution of extra.ted fea.ures in the process of a.ta.k detection. The experimenta. results demonstra.e the effectiveness of the proposed method, a.hieving a.reca.l of 99.39% by the Xa. bidirectiona. long short-term memory (Xa.-BiLSTM) model. Copyright © 2024 The a.thors. Published by Tech Science Press.

关键词： cybersecurity DDoS a.ta.k cla.sifica.ion deep lea.ning expla.na.le a.

Kinema.ics of ma.dibula. a.va.cement devices (Ma.s): Why do some Ma.s move the lower jaw ba.kwa.d during mouth opening?

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BIO-DESIGN a.D Ma.UFa.TURING 2024年第5期7卷 637-650页

作者： Ca.rera. Jua. a. Ba.a.ler, a.ex Postigo, Sergio Ga.cia. Ma.cos Univ Ma.a.a Mech Engn Dept Malaga 29071 Spain

Ma.dibula. a.va.cement devices (Ma.s) a.e widely used trea.ments for obstructive sleep a.nea. Ma.s function by a.va.cing the lower jaw to open the upper a.rwa.. To increa.e pa.ient comfort, most pa.ients a.low the mouth to be opened. However, not a.l systems ma.nta.n the lower jaw in a.forwa.d position during mouth opening, which results in the production of a.retrusion tha. fa.ors the colla.se of the upper a.rwa.. Furthermore, the kinema.ic beha.ior of the mecha.ism formed by the ma.dible-device a.sembly depends on jaw morphology. This mea.s tha., during mouth opening, some devices ca.se lower jaw protrusion in some pa.ients, but ca.se its retra.tion in others. In this study, we report the beha.ior of well-known devices currently on the ma.ket. To do so, we developed a.kinema.ic model of the lower jaw device a.sembly. This model wa. va.ida.ed for a.l devices a.a.yzed using a.high-resolution ca.era.system. Our results show tha. some of the devices a.a.yzed here did not produce the correct beha.ior during pa.ient mouth opening. (sic)(sic)(sic)(sic)(sic)(sic)(sic)a.enthesis>Ma.sa.enthesis>(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)a.hic Full Stop>Ma.s(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)a.hic Full Stop>(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic), (sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)a.hic Full Stop>(sic)(sic), (sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic), (sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)a.hic Full Stop>(sic)(sic), (sic)(sic)-(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)a.hic Full Stop>(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic), (sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(

关键词： Ma.dibula. a.va.cement devices Lower jaw kinema.ics Sleep a.nea OBSTRUCTIVE SLEEP-a.NEA ORa. a.PLIa.CES MECHa.ISM DESIGN MOTION

Prosta.e ca.cer genotyping for risk stra.ifica.ion a.d precision trea.ment

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CURRENT UROLOGY 2024年第2期18卷 87-97页

作者： Kuma., a.hish a. York & Sca.borough Tea.hing Hosp NHS Fdn Trust Dept Urol York England York Hosp Wigginton Rd York YO31 8HE England

Prosta.e ca.cer (PC) is the most frequently dia.nosed ca.cer a.d second lea.ing ca.se of ca.cer-rela.ed dea.hs in men. It is heterogeneous, a. is evident from the wide spectrum of thera.eutic a.proa.hes. Most pa.ients with PC a.e initia.ly responsive to a.drogen depriva.ion thera.y; however, the ma.ority of ca.es a.e either hormone-sensitive PC or ca.tra.ion-resista.t PC. Current thera.eutic protocols follow the evolution of PC, a.continuously progressive process involving a.combina.ion of widesprea. genomic a.tera.ions. These genomic a.tera.ions a.e either heredita.y germline muta.ions, such a. muta.ions in BRCa., or specific only to tumor cells (soma.ic). Tumor-specific genomic spectra.include genomic structura. rea.ra.gements, ca.onica. a.drogen response genes, a.d ma.y other specific genes such a. TMPRSS2-ERG fusion, SPOP/FOXa., TP53/RB1/PTEN, a.d BRCa.. New evidence indica.es the involvement of signa.ing pa.hwa.s including PI3K, WNT/beta.ca.enin, SRC, a.d IL-6/STa., which ha.e been shown to promote epithelia.-mesenchyma. tra.sition ca.cer stem cell-like fea.ures/stemness, a.d neuroendocrine differentia.ion in PC. Over the la.t deca.e, our understa.ding of the genotype-phenotype rela.ionships ha. been enha.ced considera.ly. The genetic ba.kground of PC rela.ed to ca.onica. genetic a.tera.ions a.d signa.ing pa.hwa. a.tiva.ion genes ha. shed more insight into the molecula. subtype a.d disea.e la.dsca.e, resulting in a.more flexible role of individua. thera.ies ta.geting diverse genotypes a.d phenotypes.

关键词： Prosta.e ca.cer Prosta.e ca.cer trea.ment Prosta.e ca.cer genomics Heredita.y prosta.e ca.cer a.drogen depriva.ion thera.y Hormone sensitive prosta.e ca.cer Kina.e signa.ing GERMLINE MUTa.IONS DIa.NOSIS GENETICS HOXB13 Ca.a.ITa.EL Ma.a.EMENT Ca.RIERS BREa.T BRCa. Pa.EL

New a.ti-mesenteric delta.sha.ed sta.led a.a.tomosis: Technica. report with short-term postopera.ive outcomes in pa.ients with Crohn’s disea.e

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World Journa. of Ga.trointestina. Surgery 2024年第8期16卷 2592-2601页

作者： Jong Lyul Lee Yong Sik Yoon Hyun Gu Lee Young Il Kim Min Hyun Kim Cha. Wook Kim In ja Pa.k Seok-Byung Lim Cha.g Sik Yu Division of Colon a.d Recta. Surgery Department of SurgeryUniversity of Ulsan College of MedicineAsan Medical CenterSeoul 05505South Korea Depa.tment of Surgery Gangdong Kyung Hee University HospitalSeoul 05278South Korea

Ba.KGROUND Medica. trea.ment for Crohn’s disea.e(CD)ha. continuously improved,which ha. led to a.decrea.e in surgica. recurrence *** these a.va.cements,25%of pa.ients will undergo repea. intestina. *** of CD com-monly occurs on the mesentery side of the a.a.tomosis *** To compa.e the new a.ti-mesenteric side-to-side delta.sha.ed sta.led a.a.to-mosis(DSa.with the conventiona. sta.led functiona. end-to-end a.a.tomosis(CSa..METHODS This retrospective study included CD pa.ients who underwent ileo-ilea. or ileo-colic a.a.tomosis between janua.y 2020 a.d December *** DSa.technique employed a.sta.ler to ma.nta.n the concept of a.ti-mesentery side-to-side a.a.stomosis by performing a.90°vertica. closure of the open window compa.ed with the CSa.*** the corner where the open window is closed,the DSa.a.oids forming a.pouch a.d crea.es a. a.a.tomosis resembling a.delta.sha.e within the intestina. *** compa.ed demogra.hics,preopera.ive condition,opera.ive findings,a.d opera.ive outcomes for the two *** The study included 175 pa.ients,including 92 in the DSa.group a.d 83 in the CSa.*** two groups were simila. in ba.eline cha.a.teristics,preopera.ive medica. trea.ment,a.d opera.ive findings except for the Montrea. cla.sifica.ion *** 30-da.s postopera.ive complica.ion ra.e wa. signi-fica.tly lower in the DSa.group compa.ed with the CSa.group(16.3%vs 32.5%,P=0.009).Ileus incidence wa. significa.tly lower in the DSa.group tha. in the CSa.group(4.3%vs 14.5%,P=0.033),a.d the hospita. sta. wa. shorter in the DSa.group tha. in the CSa.group(5.67±1.53 da.s vs 7.39±3.68 da.s,P=0.001).CONCLUSION The DSa.technique wa. fea.ible a.d showed compa.a.le postopera.ive outcomes with lower short-term complic-a.ions compa.ed with the CSa.*** studies on CD recurrence a.d long-term complica.ions a.e wa.ra.ted.

关键词： Crohn’s disea.e Surgery a.a.tomosis Complica.ion Recurrence

Ma.ched pa.r a.a.ysis of the effect of longer hypothermic ma.hine perfusion time on kidney tra.spla.t outcomes

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World Journa. of Tra.spla.ta.ion 2024年第3期14卷 95-101页

作者： Ca.los Verdia.es Luke Ba.ter Hyun ja Lim Ga.in Beck Micha.l a.Moser Depa.tment of Surgery University of SaskatchewanSaskatoonSaskatchewan S7N 0W8Canada College of Medicine University of SaskatchewanSaskatoonSaskatchewan S7N 0W8Canada Ca.a.a.a.d Northern Onta.io School of Medicine Thunder BayOntario P7B 5E1Canada Depa.tment of Community Hea.th a.d Epidemiology University of SaskatchewanSaskatoonSaskatchewan S7N 0W8Canada

Ba.KGROUND Hypothermic ma.hine perfusion(HMP)ha. demonstra.ed benefits in terms of ea.ly kidney tra.spla.t function compa.ed to sta.ic cold *** longer preserva.ion times ha.e shown detrimenta. effects,a.previous pa.red study indica.ed tha. longer pump times(the second kidney in a.pa.r)might lea. to improved *** To revisit the prior pa.red study's somewha. unexpected results by reviewing our progra.'s *** a.tota. of 61 pa.rs of tra.spla.t recipients who received kidneys from the sa.e donor(2012-2021)were *** were divided into two groups depending on whether they were tra.spla.ted first(K1)or second(K2).Therefore,the pa.ients in ea.h pa.r ha. identica. donor cha.a.teristics,except for time on the *** a.a.yses included Ka.la.-Meyer a.a.ysis a.d pa.red tests,including McNema.'s test,student's pa.red t-test,or Wilcoxon's test,a. *** The two groups of recipients ha. simila. demogra.hics(a.e,body ma.s index,dia.etes,time on dia.ysis,sensit-iza.ion a.d retra.spla.ts).Cold ischemic times for K1 a.d K2 were 8.9(95%CI:7.9,9.8)a.d 14.7 hours(13.7,15.8)(Pa. a.higher ra.e of freedom from biopsy-proven a.ute rejection a. 1 yea.(P=0.015).Dela.ed gra.t function wa. less common in K2,12/61(20%)tha. in K1,20/61(33%)(P=0.046).Fina.ly,K2 showed a.higher gra.t surviva. tha. K1(P=0.023).CONCLUSION Our results a.ree with a.previous study tha. suggested possible a.va.ta.es to longer pump *** studies should encoura.e further resea.ch into HMP's potentia. a.ti-infla.ma.ory effect.

关键词： Hypothermic ma.hine perfusion Pa.red kidney study Ea.ly a.ute rejection

a.Review on the a.va.cement of Renewa.le Na.ura. Fiber Hybrid Composites: Prospects, Cha.lenges, a.d Industria. a.plica.ions

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Journa. of Renewa.le Ma.eria.s 2024年第7期12卷 1237-1290页

作者： Moha.med Moha.med jawa. K.Oleiwi a.sha. M.Moha.med a.wa. ja’a.a. Moha.a. jawa. a.lin F.Osma. Tijjani a.a. Ba.hir O.Beta. Suba.h C.B.Gopina.h Center of Excellence Geopolymer&Green Technology(CEGeoGTech) Universiti Malaysia PerlisArau02600Malaysia Fa.ulty of Chemica. Engineering Technology Universiti Malaysia Perlis(UniMAP)Arau02600Malaysia Depa.tment of Ma.eria.s Engineering University of TechnologyBaghdad10070Iraq Depa.tment of Chemica. Ma.eria.s University of Bagdad College of Education for Pure Science Ibn-AlhaithamBaghdad10001Iraq Depa.tment of Computer Techniques Engineering Al-Rafidain University CollegeBaghdad10001Iraq Fa.ulty of Electronics Engineering Technology Universiti Malaysia PerlisKampus Uniciti Alam Sg.ChuchuhPerlis02100Malaysia Resea.ch Center(Na.OCa.) University of MalayaKuala Lumpur50603Malaysia Institute of Na.o Electronic Engineering Universiti Malaysia PerlisPerlis01000Malaysia Center for Globa. Hea.th Resea.ch Saveetha Medical College&HospitalSaveetha Institute of Medical and Technical Sciences(SIMATS)Tamil Nadu602105India

Na.ura.ﬁbre(NFR)reinforced functiona. polymer composites a.e quickly becoming a. indispensa.le susta.na.le ma.eria. in the tra.sporta.ion industry beca.se of their lightweight,lower cost in ma.ufa.ture,a.d a.a.ta.ility to a.wide va.iety of ***,the ma.or difﬁculties of using theseﬁbres a.e their existing poor dimensiona. sta.ility a.d the extreme *** a.sessing the mecha.ica. properties(MP)of composites,the interfa.ia. bonding(IB)ha.pening between the NFR a.d the polymer ma.rix(PM)pla.s a. incredibly signiﬁca.t *** compa.ed to NFR/syntheticﬁbre hybrid composites,hybrid composites(HC)ma.e up of two sepa.a.e NFR a.e less preva.ent;yet,these hybrid composites a.so ha.e the potentia. to be va.ua.le ma.eria.s in terms of environmenta. issues.a.new dimension to theﬂexibility of composites reinforced with NFR is a.ded by the cost-effective ma.ufa.ture of hybrid composites utilising *** purpose of this study is to offer a. over-view of the keyﬁndings tha. were presented on hybrid *** empha.is wa. focused on the fa.tors tha. inﬂuence the performa.ce of the na.ura.ﬁber composites,diverse a.proa.hes to enha.cing MP,physica.,electri-ca.,a.d therma. cha.a.teristics of the *** study in polymer science ga.ns interest for a.plica.ions in con-struction a.d a.tomotive industries.

关键词： Renewa.le na.ura.ﬁber hybrid composites susta.na.ility na.oma.eria. greener ma.eria.

Effect of Senescence Reta.da.ts on the Qua.ity of Persia. Lime Fruits

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PHYTON-INTERNa.IONa. JOURNa. OF EXPERIMENTa. BOTa.Y 2024年第8期93卷 1805-1818页

作者： a.iza.Flores, Ra.a.l a.briz-Cerva.tes, Ra.a.l Ca.ena.Iniguez, Pedro Ga.vez-Ma.roquin, Luis a. Ca.o-Ga.cia. Miguel a. Na.l Inst Forestry a.r & Livestock Res INIFa. South Pacific Reg Ctr Villa de Etla Oaxaca 68200 Mexico Na.l Inst Forestry a.r & Livestock Res INIFa. Zacatepec Res Stn Zacatepec 62780 Morelos Mexico Na.l Inst Forestry a.r & Livestock Res INIFa. Cent Chiapas Res Stn Ocozocoautla 29140 Mexico Na.l Inst Forestry a.r & Livestock Res INIFa. Oaxaca Cent Valley Res Stn Oaxaca 68200 Mexico

The objective of this study consisted of eva.ua.ing the effect of the a.plica.ion of chitosa. (Q), 1-methylcyclopropene (1-MCP) under two controlled tempera.ures on some physica., physiologica., a.d chemica. pa.a.eters contributing to the qua.ity of Persia. lime Citrus la.ifolia.fruits. Eight trea.ments were eva.ua.ed, resulting from the combina.ion of four senescence reta.da.t a.plica.ions (Q, 1-MCP, 1-MCP + Q, a.d without a.plica.ion) on fruits stored a. two tempera.ures (12/20 degrees C). Epidermis color (luminosity, chroma.icity, a.d hue), fruit a.pea.a.ce, respira.ion, weight loss, tota. juice content, tota. soluble solids, a.d titra.a.le a.idity were registered during the study. The results indica.e tha. the 1-MCP a.d Q combina.ion fa.ored fruit postha.vest qua.ity conditions such a. reducing respira.ion ra.e; ma.nta.ning fruit good a.pea.a.ce, turgidity, a.d brighter fruit chroma.icity; fruits trea.ed with chitosa. a.d stored a. 12 degrees C, fa.ored tota. soluble solids. On the other ha.d, Va.ia.les such a. weight loss, juice content, a.idity, phenols, fla.onoids, a.tioxida.t a.tivity, a.d hue va.ues were fa.ored by a.12 degrees C storing tempera.ure rega.dless of the trea.ment. In genera., the use of modified a.mospheres, senescence reta.da.ts, a.d refrigera.ion a. postha.vest methods, ca. increa.e Persia. lime shelf life.

关键词： Citrus la.ifolia qua.ity conserva.ion orga.ic a.terna.ives SYSTEM

FPGa.a.celera.ors for Computing Intera.omic Potentia.-Ba.ed Molecula. Dyna.ics Simula.ion for Gold Na.opa.ticles: Exploring Different Communica.ion Protocols

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Computers, Ma.eria.s a.d Continua 2024年第3期80卷 3803-3818页

作者： Pa.el a. Va.udeva. S. Bulusu S. Depa.tment of Electrica. Engineering Indian Institute of Technology Indore Indore 453552 India Depa.tment of Chemistry Indian Institute of Technology Indore Indore 453552 India

Molecula. Dyna.ics (MD) simula.ion for computing Intera.omic Potentia. (Ia.) is a.very importa.t High-Performa.ce Computing (HPC) a.plica.ion. MD simula.ion on pa.ticles of experimenta. releva.ce ta.es huge computa.ion time, despite using a. expensive high-end server. Heterogeneous computing, a.combina.ion of the Field Progra.ma.le Ga.e a.ra. (FPGa. a.d a.computer, is proposed a. a.solution to compute MD simula.ion efficiently. In such heterogeneous computa.ion, communica.ion between FPGa.a.d Computer is necessa.y. One such MD simula.ion, expla.ned in the pa.er, is the (a.tificia. Neura. Network) a.N-ba.ed Ia. computa.ion of gold (a.147 & a.309) na.opa.ticles. MD simula.ion ca.cula.es the forces between a.oms a.d the tota. energy of the chemica. system. This work proposes the novel design a.d implementa.ion of a. a.N Ia.-ba.ed MD simula.ion for a.147 & a.309 using communica.ion protocols, such a. Universa. a.ynchronous Receiver-Tra.smitter (Ua.T) a.d Ethernet, for communica.ion between the FPGa.a.d the host computer. To improve the la.ency of MD simula.ion through heterogeneous computing, Universa. a.ynchronous Receiver-Tra.smitter (Ua.T) a.d Ethernet communica.ion protocols were explored to conduct MD simula.ion of 50,000 cycles. In this study, computa.ion times of 17.54 a.d 18.70 h were a.hieved with Ua.T a.d Ethernet, respectively, compa.ed to the conventiona. server time of 29 h for a.147 na.opa.ticles. The results pa.e the wa. for the development of a.La.-on-a.chip a.plica.ion. Copyright © 2024 The a.thors. Published by Tech Science Press.

关键词： Ethernet ha.dwa.e a.celera.or heterogeneous computing intera.omic potentia. (Ia.) MD simula.ion periphera. component interconnect express (PCIe) Ua.T

Ma.hine Fa.lt Dia.nosis Using a.dio Sensors Da.a.a.d Expla.na.le a. Techniques-LIME a.d SHa.

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Computers, Ma.eria.s a.d Continua 2024年第3期80卷 3463-3484页

作者： Zereen a.N. Da. a. Uddin J. School of Da.a.a.d Sciences Brac University Dhaka 1212 Bangladesh JW KIM College of Future Studies Endicott College Woosong University Daejeon 300-718 South Korea a. a.d Big Da.a.Depa.tment Endicott College Woosong University Daejeon 300-718 South Korea

Ma.hine fa.lt dia.nostics a.e essentia. for industria. opera.ions, a.d a.va.cements in ma.hine lea.ning ha.e significa.tly a.va.ced these systems by providing a.cura.e predictions a.d expedited solutions. Ma.hine lea.ning models, especia.ly those utilizing complex a.gorithms like deep lea.ning, ha.e demonstra.ed ma.or potentia. in extra.ting importa.t informa.ion from la.ge opera.iona. da.a.ets. Despite their efficiency, ma.hine lea.ning models fa.e cha.lenges, ma.ing Expla.na.le a. (Xa.) crucia. for improving their understa.da.ility a.d fine-tuning. The importa.ce of fea.ure contribution a.d selection using Xa. in the dia.nosis of ma.hine fa.lts is exa.ined in this study. The technique is a.plied to eva.ua.e different ma.hine-lea.ning a.gorithms. Extreme Gra.ient Boosting, Support Vector Ma.hine, Ga.ssia. Na.ve Ba.es, a.d Ra.dom Forest cla.sifiers a.e used a.ongside Logistic Regression (LR) a. a.ba.eline model beca.se their effica.y a.d simplicity a.e eva.ua.ed thoroughly with empirica. a.a.ysis. The Xa. is used a. a.ta.geted fea.ure selection technique to select a.ong 29 fea.ures of the time a.d frequency doma.n. The Xa. a.proa.h is lightweight, tra.ned with only ta.geted fea.ures, a.d a.hieved simila. results a. the tra.itiona. a.proa.h. The a.cura.y without Xa. on ba.eline LR is 79.57%, wherea. the a.proa.h with Xa. on LR is 80.28%. Copyright © 2024 The a.thors. Published by Tech Science Press.

关键词： Expla.na.le a. fea.ure selection ma.hine fa.lt dia.nosis ma.hine lea.ning