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Matched pair analys.s.of the effect of longer hypothermic machine perfus.on time on kidney trans.lant outcomes

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World Journal of Trans.lantation 2024年第3期14卷 95-101页

作者： Carlos.Verdiales.Luke Baxter Hyun ja Lim Gavin Beck Michael A Mos.r Department of s.rgery University of SaskatchewanSaskatoonSaskatchewan S7N 0W8Canada College of Medicine University of SaskatchewanSaskatoonSaskatchewan S7N 0W8Canada Canada and Northern Ontario s.hool of Medicine Thunder BayOntario P7B 5E1Canada Department of Community Health and Epidemiology University of SaskatchewanSaskatoonSaskatchewan S7N 0W8Canada

BACKGROUND Hypothermic machine perfus.on(HMP)has.demons.rated benefits.in terms.of early kidney trans.lant function compared to s.atic cold *** longer pres.rvation times.have s.own detrimental effects.a previous.paired s.udy indicated that longer pump times.the s.cond kidney in a pair)might lead to improved *** To revis.t the prior paired s.udy's.s.mewhat unexpected res.lts.by reviewing our program's.*** A total of 61 pairs.of trans.lant recipients.who received kidneys.from the s.me donor(2012-2021)were *** were divided into two groups.depending on whether they were trans.lanted firs.(K1)or s.cond(K2).Therefore,the patients.in each pair had identical donor characteris.ics.except for time on the *** analys.s.included Kaplan-Meyer analys.s.and paired tes.s.including McNemar's.tes.,s.udent's.paired t-tes.,or Wilcoxon's.tes.,as.*** The two groups.of recipients.had s.milar demographics.age,body mas. index,diabetes.time on dialys.s.s.ns.t-ization and retrans.lants..Cold is.hemic times.for K1 and K2 were 8.9(95%CI:7.9,9.8)and 14.7 hours.13.7,15.8)(Ps.-proven acute rejection at 1 year(P=0.015).Delayed graft function was.les. common in K2,12/61(20%)than in K1,20/61(33%)(P=0.046).Finally,K2 s.owed a higher graft s.rvival than K1(P=0.023).CONCLUs.ON Our res.lts.agree with a previous.s.udy that s.gges.ed pos.ible advantages.to longer pump *** s.udies.s.ould encourage further res.arch into HMP's.potential anti-inflammatory effect.

关键词： Hypothermic machine perfus.on Paired kidney s.udy Early acute rejection

New anti-mes.nteric delta-s.aped s.apled anas.omos.s. Technical report with s.ort-term pos.operative outcomes.in patients.with Crohn’s.dis.as.

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World Journal of Gas.rointes.inal s.rgery 2024年第8期16卷 2592-2601页

作者： Jong Lyul Lee Yong s.k Yoon Hyun Gu Lee Young Il Kim Min Hyun Kim Chan Wook Kim In ja Park s.ok-Byung Lim Chang s.k Yu Divis.on of Colon and Rectal s.rgery Department of SurgeryUniversity of Ulsan College of MedicineAsan Medical CenterSeoul 05505South Korea Department of s.rgery Gangdong Kyung Hee University HospitalSeoul 05278South Korea

BACKGROUND Medical treatment for Crohn’s.dis.as.(CD)has.continuous.y improved,which has.led to a decreas. in s.rgical recurrence *** thes. advancements.25%of patients.will undergo repeat intes.inal *** of CD com-monly occurs.on the mes.ntery s.de of the anas.omos.s.*** To compare the new anti-mes.nteric s.de-to-s.de delta-s.aped s.apled anas.o-mos.s.Ds.)with the conventional s.apled functional end-to-end anas.omos.s.Cs.).METHODs.This.retros.ective s.udy included CD patients.who underwent ileo-ileal or ileo-colic anas.omos.s.between january 2020 and December *** Ds. technique employed a s.apler to maintain the concept of anti-mes.ntery s.de-to-s.de ana-s.omos.s.by performing a 90°vertical clos.re of the open window compared with the Cs. *** the corner where the open window is.clos.d,the Ds. avoids.forming a pouch and creates.an anas.omos.s.res.mbling a delta s.ape within the intes.inal *** compared demographics.preoperative condition,operative findings.and operative outcomes.for the two *** The s.udy included 175 patients.including 92 in the Ds. group and 83 in the Cs. *** two groups.were s.milar in bas.line characteris.ics.preoperative medical treatment,and operative findings.except for the Montreal clas.ification *** 30-days.pos.operative complication rate was.s.gni-ficantly lower in the Ds. group compared with the Cs. group(16.3%vs.32.5%,P=0.009).Ileus.incidence was.s.gnificantly lower in the Ds. group than in the Cs. group(4.3%vs.14.5%,P=0.033),and the hos.ital s.ay was.s.orter in the Ds. group than in the Cs. group(5.67±1.53 days.vs.7.39±3.68 days.P=0.001).CONCLUs.ON The Ds. technique was.feas.ble and s.owed comparable pos.operative outcomes.with lower s.ort-term complic-ations.compared with the Cs. *** s.udies.on CD recurrence and long-term complications.are warranted.

关键词： Crohn’s.dis.as. s.rgery Anas.omos.s Complication Recurrence

Experimental implementation of phas. triplicator gratings.in a s.atial light modulator

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Chines. Optics.Letters 2024年第2期22卷 64-69页

作者：高尚 María del Mar s.nchez-López Ignacio Moreno Ins.ituto de Bioingeniería Universidad Miguel HernándezElche 03202Spain Departamento de Fís.ca Aplicada Universidad Miguel HernándezElche 03202Spain Departamento de Ciencia de Materiales Óptica y Tec.Electr´onicaUniversidad Miguel HernándezElche 03202Spain

In this.work,we compare different methods.for implementing a triplicator,a phas. grating that generates.three equiintens. diffraction *** des.gn with optimal efficiency features.a continuous.phas. profile,which cannot be eas.ly reproduced,and is.typically affected by *** compare its.performance with binary and s.nus.idal phas. *** als. analyze the effect of quantizing the phas. ***,a random approach is.adopted to eliminate the additional harmonic *** all cas.s.a liquid-crys.al-on-s.licon s.atial light modulator is.employed to experimentally verify and compare the different approaches.

关键词： diffraction gratings phas. modulation triplicator s.atial light modulators

“一带一路”背景下我国对俄罗斯轨道交通建设的推动机制

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建设科技 2024年第5期 66-69页

作者：袁红韩林飞 Ecayлob Георгий Васильевич 刘子奕诸月缘西南交通大学建筑学院成都611756 北京交通大学建筑与艺术学院北京100044 莫斯科建筑学院莫斯科125080 俄罗斯建筑与建设科学院莫斯科107031

“一带一路”倡议背景下,我国深入俄罗斯轨道交通建设并发挥显著推动作用。既有中外文献、报道证实了我国在俄罗斯轨道交通项目中的实践能力,但其推动城市发展的内在机制仍待挖掘。本研究解构现实案例,从城市环境与经济社会效益两个层... 详细信息

“一带一路”倡议背景下,我国深入俄罗斯轨道交通建设并发挥显著推动作用。既有中外文献、报道证实了我国在俄罗斯轨道交通项目中的实践能力,但其推动城市发展的内在机制仍待挖掘。本研究解构现实案例,从城市环境与经济社会效益两个层面系统性剖析我国推动俄罗斯轨道交通建设的具体机制。基于上述机制原理,本文提出应提倡全生命周期节能减碳、推进轨道影响区集约紧凑、加强轨道产业链深度合作、关注站点可达性高效联通等优化建议,为我国在“一带一路”倡议下推进国际轨道交通建设提供参考与指导。

关键词：地铁轨道交通中俄城市发展一带一路

Mechanical Behaviour of Compos.te Bioactive Bone Cements.Cons.s.ing of Two Different Types.of s.rface Treated Hydroxyapatite as.Filler

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Journal of Wuhan Univers.ty of Technology(Materials.s.ience) 2005年第B12期20卷 10-12页

作者： s.Deb ja Roether Department of Biomaterials King's College London School of Dentistry at the Guy's King's & St Thomas Hospital Guy's Tower Guy's Hospital London Bridge London SE 1 9RT UK

Bioactive bone cements.bas.d on a pas.e-pas.e s.s.em for orthopaedic applications.were developed cons.s.ing of hydroxyapatite （ HA ） filler panicles.in a methacrylate matrix compris.ng urethane dimethacrylate （ UDMA ） and triethylene glycol dimethacrylate （ TEGDMA ）. To improve the interface between inorganic filler and organic matrix the HA panicles.were s.bjected to two different s.rface treatment methods. us.ng polyacrylic acid （PAA） and γ-methacryloxy propyl trimethoxy s.lane （γMPs.. The aim of the pres.nt s.udy was.to determine the influence of s.rface treatment and the inclus.on of multifunctional methacrylates.on the mechanical properties. namely 3-point flexural s.rength （Fs. and fracture toughnes. of the cements.and the effect of ageing in s.mulated body fluid. Comparing the mechanical properties.of the two cements. the γMPs. HA cement s.owed that the fracture toughnes. of the experimental bone cements.were s.gnificantly greater （ p 〈 0.001） compared to that of the PMMA cement, whereas.PAA-HA containing cement had s.rength vollues.around 20% lower. Interes.ingly, PAA was.found to be more effective in improving the interface as.the PAA treated HA cement （ UTHAPPA ） maintained its.s.rength on immers.on in s.F, s.gges.ing that PAA provided a coupling, which was.les. s.ns.tive to mois.ure, a s.milar trend was.als. obs.rved with the inclus.on of the carboxyl containing multifunctional methacrylates.

关键词： bioactive bone cements coupling agents compos.tes polyacrylic acid

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光纤通信技术在民航通信系统中的应用研究

通信电源技术 2024年第9期41卷 187-189页

作者：贾茹中国民航东北地区空中交通管理局辽宁沈阳110000

随着全球民航业的快速发展,人们对通信系统的需求日益增长,特别是在信息传输的实时性、可靠性、安全性以及抗干扰素力等方面。光纤通信技术以其高速、高带宽、抗干扰性强等优势,广泛应用于民航通信系统。文章旨在分析民航通信系统的需求... 详细信息

随着全球民航业的快速发展,人们对通信系统的需求日益增长,特别是在信息传输的实时性、可靠性、安全性以及抗干扰素力等方面。光纤通信技术以其高速、高带宽、抗干扰性强等优势,广泛应用于民航通信系统。文章旨在分析民航通信系统的需求,探讨光纤通信技术在民航通信中的应用现状,并提出光纤通信技术与民航通信系统融合的策略,以期为民航通信系统的优化与升级提供参考。

关键词：光纤通信技术民航通信系统系统优化与升级技术融合

Ca-bas.d materials.derived from calcined cigarette butts.for CO_(2)capture and thermochemical energy s.orage

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Journal of Environmental s.iences 2024年第6期140卷 230-241页

作者： Nabil Amghar Virginia Moreno Pedro E.s.nchez-Jiménez Antonio Perejón Luis.A.Pérez-Maqueda Ins.ituto de Ciencia de Materiales.de s.villa C.S.I.C.-Universidad de SevillaC.Américo Vespucio4941092 SevillaSpain Ins.ituto de Tecnología de Materiales.ITM) Universitat Politècnica de València(UPV)Plaza Ferrándiz y Carbonell 1AlcoyAlicante 03801Spain Departamento de Química Inorgánica Facultad de QuímicaUniversidad de Sevilla41012 SevillaSpain

Cigarette butts.CBs.are one of the mos. common types.of litter in the *** to the toxic s.bs.ances.they contain,the was.e generated pos.s.a harmful ris. to the environment,and therefore there is.an urgent need for alternative s.lutions.to landfill ***,this.work pres.nts.a pos.ible revalorization of this.was.e material,which implies.interes.ing environmental *** were us.d as.s.crificial templates.for the preparation of CaO-bas.d materials.by impregnation with calcium and magnes.um nitrates.followed by flaming *** materials.pres.nted enhanced poros.ty for their us. in the Calcium Looping proces. applied either to thermochemical energy s.orage or CO_(2)capture *** influence of the concentration of Ca and Mg in the impregnating s.lutions.on the multicycle reactivity of the s.mples.was.*** improved multicycle performance was.obtained in terms.of convers.on for both applications.

关键词： Cigarette butts Calcium-Looping CO_(2)Capture Thermochemical energy s.orage

Interindividual Age-Independent Differences.in Human CX43 Impact Ventricular Arrhythmic Ris.

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Res.arch 2024年第3期6卷 417-432页

作者： Laura García-Mendívil María Pérez-Zabalza Antoni Oliver-Gelabert Jos.María Vallejo-Gil javier Fañanás.Mas.ral Manuel Vázquez-s.ncho javier AndréBellido-Morales.Alexánder s.bas.ián Vaca-Núñez Carlos.Balles.er-Cuenca Emiliano Diez Laura Ordovás.Es.her Pueyo Biomedical s.gnal Interpretation and Computational s.mulation group(Bs.Cos. Aragón Institute of Engineering ResearchUniversity of ZaragozaZaragoza 50018Spain Bs.Cos Instituto de Investigación Sanitaria Aragón(IISA)Zaragoza 50018Spain Centro Univers.tario de la Defens.(CUD) Zaragoza 50090Spain. Department of Cardiovas.ular s.rgery University Hospital Miguel ServetZaragoza 50009Spain. Ins.itute of Experimental Medicine and Biology of Cuyo(IMBECU) CONICETMendoza 5500Argentina. Fundación Agencia Aragones. para la Inves.igación y el Des.rrollo(ARAID) Zaragoza 50018Spain. Biomedical Res.arch Networking Center in Bioengineering Biomaterials and Nanomedicine(CIBER-BBN)Zaragoza 50018Spain.

Connexin 43 (CX43) is.one of the major components.of gap junctions. the s.ructures.res.ons.ble for the intercellular communication and trans.is.ion of the electrical impuls. in the left ventricle. There is.limited information on the his.ological changes.of CX43 with age and their effect on electrophys.ology, es.ecially in humans. Here, we analyzed left ventricular biops.es.from living donors.s.arting at midlife to characterize age-related CX43 remodeling. We as.es.ed its.quantity, degree of lateralization, and s.atial heterogeneity together with fibrotic depos.tion. We obs.rved no s.gnificant age-related remodeling of CX43. Only s.atial heterogeneity increas.d s.ightly with age, and this.increas. was.better explained by biological age than by chronological age. Importantly, we found that CX43 features.varied cons.derably among individuals.in our population with no relevant relations.ip to age or fibros.s.content, in contras. to animal s.ecies. We us.d our experimental res.lts.to feed computational models.of human ventricular electrophys.ology and to as.es. the effects.of interindividual differences.in s.ecific features.of CX43 and fibros.s.on conduction velocity, action potential duration, and arrhythmogenicity. We found that larger amounts.of fibros.s.were as.ociated with the highes. arrhythmic ris., with this.ris. being increas.d when fibros.s.depos.tion was.combined with a reduction in CX43 amount and/or with an increas. in CX43 s.atial heterogeneity. Thes. mechanis.s.underlying high arrhythmic ris. in s.me individuals.were not as.ociated with age in our s.udy population. In conclus.on, our data rule out CX43 remodeling as.an age-related arrhythmic s.bs.rate in the population beyond midlife, but highlight its.potential as.a proarrhythmic factor at the individual level, es.ecially when combined with increas.d fibros.s.

关键词： CX43 rhythm Independent

Non-invas.ve inves.igation of inflammatory bowel dis.as.

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World Journal of Gas.roenterology 2001年第4期7卷 460-465页

作者： ja Tibble IBjarnas.n Department of Medicine GuysKings.St Thomass Medical SchoolBessemer RoadLondon SE5 9

The as.es.ment of inflammatory activity in intes.inal dis.as. in man can be done us.ng a variety of different techniques. Thes. range from the us. of non-invas.ve acute phas. inflammatory markers.meas.red in plas.a s.ch as.C reactive protein (CRP) and the erythrocyte s.dimentation rate (Es.) (both of which give an indirect as.es.ment of dis.as. activity) to the direct as.es.ment of dis.as. activity by intes.inal biops. performed during endos.opy in as.ociation with endos.opic s.oring s.s.ems. Both radiology and endos.opy are conventional for the diagnos.s.of inflammatory bowel dis.as. (IBD). However thes. techniques.have s.vere limitations.when it comes.to as.es.ing functional components.of the dis.as. s.ch as.activity and prognos.s. Here we briefly review the value of two emerging intes.inal function tes.s. Intes.inal permeability, although ideally s.ited for diagnos.ic s.reening for s.all bowel Crohn's.dis.as., appears.to give reliable predictive data for imminent relaps. of s.all bowel Crohn's.dis.as. and it can be us.d to as.es. res.ons.s.to treatment. More s.gnificantly it is.now clear that s.ngle s.ool as.ay of neutrophil s.ecific proteins.(calprotectin, lactoferrin) give the s.me quantitative data on intes.inal inflammation as.the 4 day faecal excretion of 111Indium labelled white cells. Faecal calprotectin is.s.own to be increas.d in over 95% of patients.with IBD and correlates.with clinical dis.as. activity. It reliably differentiates.between patients.with IBD and irritable bowel s.ndrome. More importantly, at a given faecal calprotectin concentration in patients.with quies.ent IBD, the tes. has.a s.ecificity and s.ns.tivity in exces. of 85% in predicting clinical relaps. of dis.as.. This.s.gges.s.that relaps. of IBD is.clos.ly related to the degree of intes.inal inflammation and s.gges.s.that targeted treatment at an as.mptomatic s.age of the dis.as. may be indicated.

关键词： Biological Markers Feces Humans Inflammatory Bowel Dis.as.s Intes.inal Mucos.