检索结果-南通市图书馆

Molecular Cloning and Functional characterization of the Tomato E3 Ubiquitin Ligase slBAH1 Gene

在线全文

学校读者我要写书评

暂无评论

Molecular Cloning and Functional Characterization of the Tom...

Reversal of age-associated frailty by controlled physical exercise:The pre-clinical and clinical evidences

中国植物病理学会2016年学术年会

作者： ZHOU s M WANG s M LIN C sONG Y Z ZHENG X X sONG F M ZHU C X state Key laboratory of Crop Biology Shandong Key Laboratory of Crop BiologyShandong Agricultural University

Emerging evidence sugges.s.that E3 ligas.s.play critical roles in diverse biological process.s.including pathogen res.s.ance in *** this.s.udy,an ubiquitin ligase gene（slBAH1）was cloned from a tomato plant,and the functions of the gene were *** slBAH1 gene contained1002 nucleotides and encoded a protein with 333 amino *** slBAH1 protein contained a sPX domain and a RING ***1 displayed E3 ubiquitin ligase activity in ***1 was demonstrated to localize in the nucleus,cytoplasm and plasma membrane by a subcellular localization *** expression of slBAH1 was induced by various hormones and Botrytis cinerea ***1-silencing in plants obtained by Virus-induced gene silencing（VIGs） technology enhanced res.s.ance to Botrytis cinerea,and the expression of pathogenes.s.related（PR） genes,including PR1,PR2,PR4,PR5,and PR7,was.s.gnificantly *** results indicated that the slBAH1-dependent activation of defense-related genes played a key role in the enhanced fungal res.s.ance observed in the slBAH1-silenced plants and may be related to the sA-dependent and ja-dependent signaling pathways.

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

sports Medicine and Health science 2019年第1期1卷 33-39页

作者： C.Arc-chagnaud F.Millan A.salvador-Pascual A.G.Correas G.Olaso-Gonzalez A.De la Rosa A.Carretero M.C.Gomez-Cabrera J.Viña Freshage Research Group Department of PhysiologyFaculty of MedicineUniversity of Valencia and CIBERFESFundacion Investigacion Hospital Clínico Universitario/INCLIVAValenciaSpain INRA UMR866 Dynamique Musculaire et MetabolismeUniversite de MontpellierF-34060MontpellierFrance

Demographic aging is one of the most serious challenges facing our *** we live longer,we do not live better because it is considered that approximately 16–20%of our life is.s.ent in late-life *** people have the greatest risk of developing frailty increasing the risk of presenting various adverse health events.s.ch as low quality of life,disability,hospitalization and even *** men and women over 65 years old have lower muscle quality and muscle mass and higher percentage of body fat than non-frail people of the same *** this review we will address the main physiological changes in the muscular and nervous.s.stem associated to *** specifically we will review the changes in muscle mass,quality,and strength relating them with the decrease in capillarization and muscular oxidative capacity as well as with the alterations in protein synthes.s.in the muscle with *** last section of the manuscript will be devoted to the animal models of frailty and the indexes developed to measure frailty in these *** will finally address the importance of exercise training as an intervention to delay or even reverse frailty.

关键词： sarcopenia Multicomponent exercise Disability skeletal muscle Healthy aging

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

s波段FMCW雷达单天线工作开关系统

电光系统 1994年第4期 53-60页

作者： Greg.,ja 孙明甫

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

战后日本天皇出访的政策决定过程及政治内涵

东北亚学刊 2020年第5期 120-131,151,152页

作者：龚娜天津社会科学院日本研究所

战后日本回归国际社会后,保守政权希望通过天皇出访,重新打造天皇"国家元首"的形象。为实现天皇出访,日本政府首先提出"公事"的概念,讨论并制定了有关委任天皇国事行为的法案。继而,在天皇出访的政治实践上,在几届内阁的推动下,以访欧... 详细信息

战后日本回归国际社会后,保守政权希望通过天皇出访,重新打造天皇"国家元首"的形象。为实现天皇出访,日本政府首先提出"公事"的概念,讨论并制定了有关委任天皇国事行为的法案。继而,在天皇出访的政治实践上,在几届内阁的推动下,以访欧的尝试,开创了天皇出访的先例, 再以访美的实践,正式拉开"皇室外交"的历史帷幕。天皇出访名为"皇室国际亲善",但其蕴含的政治含义亦难掩饰。天皇出访不仅动摇了象征天皇制体系,实现了天皇形象"元首化"的政治目的,还以"皇室外交"为途径,重新诠释了天皇制度的政治内涵。与此同时,昭和天皇的战争责任问题再次受到关注。经过昭和、平成两个时代,"皇室外交"已被注入新的内涵。在令和时代,继承"平成流"的"皇室外交"、努力避免更多的政治利用,成为皇室的新课题。

关键词：天皇出访皇室外交象征天皇制政治内涵

Towards in vivo amplification: Overcoming hurdles in the use of hematopoietic stem cells in transplantation and gene therapy

在线全文

学校读者我要写书评

暂无评论

World Journal of stem Cells 2015年第11期7卷 1233-1250页

作者： Murtaza s nagree Lucía López-Vásquez Jeffrey A Medin Department of Medical Biophysics Faculty of Medicine University of Toronto Institute of Medical science Faculty of Medicine University of Toronto University Health Network

With the advent of safer and more efficient gene transfer methods, gene therapy has become a viable solution for many inherited and acquired disorders. Hematopoietic stem cells(Hs.s. are a prime cell compartment for gene therapy aimed at correcting blood-based disorders, as well as those amenable to metabolic outcomes that can effect cross-correction. While some resounding clinical success.s.have recently been demonstrated, ample room remains to increase the therapeutic output from HsC-directed gene therapy. In vivo amplification of therapeutic cells is one avenue to achieve enhanced gene product delivery. To date, attempts have been made to provide Hs.s.with res.s.ance to cytotoxic drugs, to include druginducible growth modules.s.ecific to Hs.s. and to increase the engraftment potential of transduced Hs.s. This review aims to summarize amplification strategies that have been developed and tested and to discuss their advantages along with barriers faced towards their clinical adaptation. In addition, next-generation strategies to circumvent current limitations of specific amplification schemas are discussed.

关键词： Gene therapy Hematopoietic stem cells In vivo selection Chemical Inducer of Dimerization Chemo-selection Lentivirus

HIGH sTRAIN RATE sUPERPlasTICITY OF A AIN PARTICUlaTE REINFORCED 6061Al COMPOsITE

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acta Metallurgica sinica(English Letters) 2001年第2期14卷 127-131页

作者： L.H. Han, J.T. Niu and D.M. Jiang (The national Key laboratory of Advanced Welding Production Technology, Harbin Institute of Technology,Harbin 150001, China) T. Imai (national Industrial Research Institute of nagoya. 1 Hirate-cho, Kita-ku, nagoya.462, ja Harbin Inst. of Technol. Harbin 150001 China

The superplasticity of AINp/6061Al composite, fabricated by powder metallurgy method and hot-rolled after extrusion, was investigated. The AINp/6061Al composite exhibits an m-value of 0.49 and a maximum elongation of 438% in the strain rates ranging hem 10-2-100s-1 and at temperatures from 823K to 893K. Diffirential scanning calorimeter was used to ascertain the possibility of any partial melting in the vicinity of optimum superplastic temperature. These results.s.ggested that liquid phase existed where maximum elongation was obtained.

关键词： superplasticity aluminum matrix composite AIN particulate

泡沫分散聚合法制备超大孔水凝胶及其性能研究

在线全文

学校读者我要写书评

暂无评论

高分子通报 2011年第5期 76-81页

作者：王立华林松柏王克平王娜娜华侨大学材料科学与工程学院泉州362021 黎明职业大学泉州362000

采用泡沫分散聚合法,以自制的4-乙酰基丙烯酰乙酸乙酯(AAEA)和2-丙烯酰胺基-2-甲基丙磺酸(AMPs)、丙烯酸(AA)为单体,制备了具有相互贯穿超大孔结构的快速响应型水凝胶。结果表明,引发剂和交联剂用量分别为2.5%和0.6%时平衡溶胀度最高;... 详细信息

采用泡沫分散聚合法,以自制的4-乙酰基丙烯酰乙酸乙酯(AAEA)和2-丙烯酰胺基-2-甲基丙磺酸(AMPs)、丙烯酸(AA)为单体,制备了具有相互贯穿超大孔结构的快速响应型水凝胶。结果表明,引发剂和交联剂用量分别为2.5%和0.6%时平衡溶胀度最高;当以饱和碳酸钠溶液为发泡剂时制得的凝胶孔洞均匀贯穿;凝胶经无水乙醇处理后,其表面孔洞的形成增大了与溶液的接触面积;该凝胶20s内即可达到溶胀/消溶胀平衡具有良好的离子强度敏感性;在蒸馏水和naCl溶液之间具有良好的反复溶胀/消溶胀性能。

关键词：水凝胶泡沫分散聚合快速响应离子敏感

最新ja.a.2核心技术卷1 原理原书第5版 5

在线全文

学校读者我要写书评

暂无评论

Early palliative care for patients with metastatic non-small-cell lung cancer

丛书名： sun公司核心技术丛书

2002年

作者：（美）Cay s.Horstmann （美）Gary Cornell 李如豹刚冬梅等译

本书覆盖了ja.a.平台标准版1.3的基础知识，对面向对象的ja.a.发、swing用户界面组件以及其他一些技术进行了深入讨论。

ISBN: (数字)7111095839

ISBN: (纸本)7111095839

本书覆盖了ja.a.平台标准版1.3的基础知识，对面向对象的ja.a.发、swing用户界面组件以及其他一些技术进行了深入讨论。

关键词： ja.a.言程序设计

来源：畅想之星图书光盘版（南... 评论

在线全文

畅想之星图书光盘版（南通市图书馆镜像）

学校读者我要写书评

暂无评论

中国肺癌杂志 2010年第9期13卷 897-897页

作者： Temel Js Greer ja Muzikansky A Gallagher ER Admane s jackson VA Dahlin CM Blinderman CD jacobsen J Pirl WF Billings ja Lynch TJ

Comments This landmark article demonstrates that integration of early palliative care with standard oncologic practice shortly after diagnos.s.may improve quality of life,mood,and overall survival for adults with advanced non-small-cell lung cancer（NsCLC）.If validated,these findings could support a paradigm shift in the care of adults with metastatic NsCLC and possibly patients with other tumor types characterized by short survival and high symptom burden.

关键词：肺癌症状临床分析患者