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Matched pair analysis of the effect of longer hypothermic machine perfusion time on kidney transplant outcomes

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World Journal of Transplantation 2024年第3期14卷 95-101页

作者： Carlos Verdiales Luke Baxter Hyun ja Lim Gavin Beck Michael A Moser Department of Surgery University of SaskatchewanSaskatoonSaskatchewan S7N 0W8Canada College of Medicine University of SaskatchewanSaskatoonSaskatchewan S7N 0W8Canada Canada and Northern Ontario School of Medicine Thunder BayOntario P7B 5E1Canada Department of Community Health and Epidemiology University of SaskatchewanSaskatoonSaskatchewan S7N 0W8Canada

BACKGROUND Hypothermic machine perfusion(HMP)has demonstrated benefits in terms of early kidney transplant function compared to static cold *** longer preservation times have shown detrimental effects,a previous paired study indicated that longer pump times(the second kidney in a pair)might lead to improved *** To revisit the prior paired study's somewhat unexpected results by reviewing our program's *** A total of 61 pairs of transplant recipients who received kidneys from the same donor(2012-2021)were *** were divided into two groups depending on whether they were transplanted first(K1)or second(K2).Therefore,the patients in each pair had identical donor characteristics,except for time on the *** analyses included Kaplan-Meyer analysis and paired tests,including McNemar's test,student's paired t-test,or Wilcoxon's test,as *** The two groups of recipients had similar demographics(age,body mass index,diabetes,time on dialysis,sensit-ization and retransplants).Cold ischemic times for K1 and K2 were 8.9(95%CI:7.9,9.8)and 14.7 hours(13.7,15.8)(P0.0001),***,K2 had a higher rate of freedom from biopsy-proven acute rejection at 1 year(P=0.015).Delayed graft function was less common in K2,12/61(20%)than in K1,20/61(33%)(P=0.046).Finally,K2 showed a higher graft survival than K1(P=0.023).CONCLUSION Our results agree with a previous study that suggested possible advantages to longer pump *** studies should encourage further research into HMP's potential anti-inflammatory effect.

关键词： Hypothermic machine perfusion Paired kidney study Early acute rejection

A Review on the Advancement of Renewable Natural Fiber Hybrid Composites: Prospects, Challenges, and Industrial Applications

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Journal of Renewable Materials 2024年第7期12卷 1237-1290页

作者： Mohammed Mohammed jawad K.Oleiwi Aeshah M.Mohammed Anwar ja’afar Mohamad jawad Azlin F.Osman Tijjani Adam Bashir O.Betar Subash C.B.Gopinath Center of Excellence Geopolymer&Green Technology(CEGeoGTech) Universiti Malaysia PerlisArau02600Malaysia Faculty of Chemical Engineering Technology Universiti Malaysia Perlis(UniMAP)Arau02600Malaysia Department of Materials Engineering University of TechnologyBaghdad10070Iraq Department of Chemical Materials University of Bagdad College of Education for Pure Science Ibn-AlhaithamBaghdad10001Iraq Department of Computer Techniques Engineering Al-Rafidain University CollegeBaghdad10001Iraq Faculty of Electronics Engineering Technology Universiti Malaysia PerlisKampus Uniciti Alam Sg.ChuchuhPerlis02100Malaysia Research Center(NANOCAT) University of MalayaKuala Lumpur50603Malaysia Institute of Nano Electronic Engineering Universiti Malaysia PerlisPerlis01000Malaysia Center for Global Health Research Saveetha Medical College&HospitalSaveetha Institute of Medical and Technical Sciences(SIMATS)Tamil Nadu602105India

Naturalﬁbre(NFR)reinforced functional polymer composites are quickly becoming an indispensable sustainable material in the transportation industry because of their lightweight,lower cost in manufacture,and adaptability to a wide variety of ***,the major difﬁculties of using theseﬁbres are their existing poor dimensional stability and the extreme *** assessing the mechanical properties(MP)of composites,the interfacial bonding(IB)happening between the NFR and the polymer matrix(PM)plays an incredibly signiﬁcant *** compared to NFR/syntheticﬁbre hybrid composites,hybrid composites(HC)made up of two separate NFR are less prevalent;yet,these hybrid composites also have the potential to be valuable materials in terms of environmental issues.A new dimension to theﬂexibility of composites reinforced with NFR is added by the cost-effective manufacture of hybrid composites utilising *** purpose of this study is to offer an over-view of the keyﬁndings that were presented on hybrid *** emphasis was focused on the factors that inﬂuence the performance of the naturalﬁber composites,diverse approaches to enhancing MP,physical,electri-cal,and thermal characteristics of the *** study in polymer science gains interest for applications in con-struction and automotive industries.

关键词： Renewable naturalﬁber hybrid composites sustainability nanomaterial greener material

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光纤通信技术在民航通信系统中的应用研究

通信电源技术 2024年第9期41卷 187-189页

作者：贾茹中国民航东北地区空中交通管理局辽宁沈阳110000

随着全球民航业的快速发展,人们对通信系统的需求日益增长,特别是在信息传输的实时性、可靠性、安全性以及抗干扰素力等方面。光纤通信技术以其高速、高带宽、抗干扰性强等优势,广泛应用于民航通信系统。文章旨在分析民航通信系统的需求... 详细信息

随着全球民航业的快速发展,人们对通信系统的需求日益增长,特别是在信息传输的实时性、可靠性、安全性以及抗干扰素力等方面。光纤通信技术以其高速、高带宽、抗干扰性强等优势,广泛应用于民航通信系统。文章旨在分析民航通信系统的需求,探讨光纤通信技术在民航通信中的应用现状,并提出光纤通信技术与民航通信系统融合的策略,以期为民航通信系统的优化与升级提供参考。

关键词：光纤通信技术民航通信系统系统优化与升级技术融合

不同益生菌对亚东鲑生长性能和生化指标的影响

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西南农业学报 2024年第5期37卷 1116-1123页

作者：何文佳王万良张忭忭西藏自治区农牧科学院水产科学研究所拉萨850000 西藏土著鱼类繁育与利用技术工程研究中心拉萨850000 西藏自治区渔业与种质资源利用重点实验室拉萨850000 中国水产科学研究院东海水产研究所上海200090

【目的】旨在探讨饲料中添加不同益生菌对亚东鲑(Salmo trutta)生长性能、消化酶活性和血清生化指标的影响。【方法】选择初始体质量为(84.57±1.83)g的亚东鲑鱼种630尾,随机分成7组,每组3个平行,每个平行30尾。对照组投喂基础饲料,实... 详细信息

【目的】旨在探讨饲料中添加不同益生菌对亚东鲑(Salmo trutta)生长性能、消化酶活性和血清生化指标的影响。【方法】选择初始体质量为(84.57±1.83)g的亚东鲑鱼种630尾,随机分成7组,每组3个平行,每个平行30尾。对照组投喂基础饲料,实验组分别添加不同益生菌(酵母菌、EM菌、乳酸菌、枯草芽孢杆菌、复合芽孢杆菌、地衣芽孢杆菌)至基础饲料,饲养3个月。【结果】添加不同益生菌对亚东鲑都具有促生长作用,试验组体长增长率、增重率、特定生长率、食物转化率和摄食率等指标均显著高于对照组(P0.05,下同);与对照组相比,试验组肝胰脏蛋白酶、肠道蛋白酶、脂肪酶、淀粉酶均升高,其中EM菌组最高,显著高于其他各试验组;与对照组相比,酵母菌组血清中过氧化氢酶活性显著升高,总蛋白、甘油三酯、葡萄糖、超氧化物歧化酶、酸性磷酸酶、谷草转氨酶、谷丙转氨酶、补体C3和溶菌酶指标差异不显著(P>0.05),而其他菌组之间均有不同程度影响。【结论】综合考虑存活率、生长特性、消化酶活性和血清生化指标,添加EM菌对亚东鲑健康养殖效果较好。

关键词：亚东鲑益生菌生长性能生化指标

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多规格转台轴承组件的自动紧钉装置

制造技术与机床 2024年第6期 183-188页

作者：王凯韩银平贾长安黄胜军西安精雕精密机械工程有限公司陕西西安710000 北京精雕科技集团有限公司北京102308

在装配转台轴承组件时,需要按照十字交叉顺序分三步拧紧固定螺钉,现有的装紧钉方式存在效率低和紧钉质量低等问题。文章设计了一种多规格转台轴承组件的自动紧钉装置,实现了多规格转台轴承组件的自动定位夹紧、装钉、按照十字交叉顺序... 详细信息

在装配转台轴承组件时,需要按照十字交叉顺序分三步拧紧固定螺钉,现有的装紧钉方式存在效率低和紧钉质量低等问题。文章设计了一种多规格转台轴承组件的自动紧钉装置,实现了多规格转台轴承组件的自动定位夹紧、装钉、按照十字交叉顺序分三步加扭力和加胶功能。实际使用表明,该设备工作可靠、效率高,紧钉质量得到很大提高。

关键词：转台轴承组件自动拧紧力矩螺钉

表面活性剂对CaO_(2)修复石油烃污染土壤的影响研究

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环境科技 2024年第2期37卷 1-6,12页

作者：张祥孙勇向甲甲上海市政工程设计研究总院(集团)有限公司上海200092 上海申环环境工程有限公司上海200092

将合成的纳米级过氧化钙(nCaO_(2))用于石油烃污染土壤修复,研究过氧化钙(CaO_(2))、柠檬酸(CA)螯合二价铁(Fe(Ⅱ))投加量对石油烃去除效果的影响,并将不同表面活性剂对石油烃氧化的影响进行比较。结果表明,随着CaO_(2)或CA螯合Fe(Ⅱ)... 详细信息

将合成的纳米级过氧化钙(nCaO_(2))用于石油烃污染土壤修复,研究过氧化钙(CaO_(2))、柠檬酸(CA)螯合二价铁(Fe(Ⅱ))投加量对石油烃去除效果的影响,并将不同表面活性剂对石油烃氧化的影响进行比较。结果表明,随着CaO_(2)或CA螯合Fe(Ⅱ)的投加量增大,石油烃去除率均呈先增后降趋势。当n(CaO_(2)):n(Fe(Ⅱ)):n(CA)为4:1:1时,石油烃去除效果最佳,达到70.98%。十二烷基硫酸钠和曲拉通X-100对土壤中石油烃均有较好的增溶效果。质量浓度为3g/L的十二烷基硫酸钠对石油烃的降解可起促进作用,而曲拉通X-100则不利于石油烃的降解。

关键词：过氧化钙石油烃表面活性剂化学氧化纳米材料

山楂叶总黄酮通过miR-21a-5p对血管紧张素Ⅱ诱导的心肌细胞肥大的影响

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中国临床药理学杂志 2024年第15期40卷 2182-2186页

作者：田林燕朱冉代聚平王佳佳张斌南阳医学高等专科学校内科教研室河南南阳473000 南阳医学高等专科学校临床实训室河南南阳473000 南阳医学高等专科学校第一附属医院心血管内科河南南阳473000 南阳医学高等专科学校第一附属医院病理科河南南阳473000

目的探讨山楂叶总黄酮对血管紧张素Ⅱ(AngⅡ)诱导的心肌肥大的影响,及其可能作用机制。方法将H9c2细胞分为对照组(正常培养),模型组(100 nmol·L^(-1)AngⅡ处理24 h),低、中、高剂量实验组(先给予100 nmol·L^(-1)AngⅡ处理24 h后,再分... 详细信息

目的探讨山楂叶总黄酮对血管紧张素Ⅱ(AngⅡ)诱导的心肌肥大的影响,及其可能作用机制。方法将H9c2细胞分为对照组(正常培养),模型组(100 nmol·L^(-1)AngⅡ处理24 h),低、中、高剂量实验组(先给予100 nmol·L^(-1)AngⅡ处理24 h后,再分别给予25、50、100 mg·L^(-1)的山楂叶总黄酮处理24 h),anti-miR-NC、anti-miR-21a-5p组(分别转染anti-miR-NC、anti-miR-21a-5p后,给予100 nmol·L^(-1)AngⅡ处理24 h),miR-NC+高剂量组和miR-21a-5p+高剂量组(分别转染miR-NC、miR-21a-5p mimics,再给予100 nmol·L^(-1)AngⅡ+100 mg·L^(-1)山楂叶总黄酮各处理24 h)。用CCK-8法和流式细胞术检测细胞活力和凋亡情况,用实时荧光定量聚合酶链反应法检测miR-21a-5p的表达水平,用蛋白质印迹法检测环氧化酶-2(COX2)/前列腺素E2(PGE2)的表达水平。结果对照组、模型组和高剂量实验组的细胞活力分别为1.03±0.09、0.51±0.05和0.93±0.08,凋亡率分别为(7.69±0.61)%、(23.04±1.82)%和(9.43±0.71)%,miR-21a-5p表达水平分别为1.00±0.09、2.43±0.18和1.09±0.08,COX2蛋白相对表达水平分别为0.42±0.03、0.85±0.08和0.40±0.04,PGE2蛋白相对表达水平分别为0.34±0.03、0.75±0.07和0.35±0.03,模型组的上述指标与高剂量实验组和对照组相比,在统计学上差异均有统计学意义(均P0.05)。anti-miR-NC组、anti-miR-21a-5p组、miR-NC+高剂量组和miR-21a-5p+高剂量组的细胞活力分别为0.52±0.04、1.12±0.08、0.94±0.09和0.57±0.04,凋亡率分别为(23.04±1.82)%、(9.86±0.73)%、(9.47±0.64)%和(24.96±1.94)%,miR-21a-5p表达水平分别为1.00±0.10、0.43±0.04、1.00±0.09和2.12±0.18,COX2蛋白相对表达水平分别为0.86±0.05、0.39±0.04、0.41±0.03、0.78±0.07,PGE2蛋白相对表达水平分别为0.74±0.06、0.38±0.07、0.36±0.02、0.71±0.05,anti-miR-21a-5p组的上述指标与anti-miR-NC组比较,miR-21a-5p+高剂量组的上述指标与miR-NC+高剂量组比较,在统计学上差异均有统计学意义(均P0.05)。结论山楂叶总黄酮通过调控miR-21a-5p和COX2/PGE2通路的表达,从而抑制AngⅡ诱导的心肌肥大。

关键词：山楂叶总黄酮心肌肥大血管紧张素Ⅱ 细胞增殖凋亡

Curing Kinetics of Tannin and Lignin Biobased Adhesives Determined by DSC and ABES

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Journal of Renewable Materials 2022年第8期10卷 2117-2131页

作者： jaša Saražin Ida Poljanšek Antonio Pizzi MilanŠernek University of Ljubljana Biotechnical FacultyLjubljana1000Slovenia Universitéde Lorraine LERMAB-ENSTIB Epinal88000France

The curing process of two biobased adhesives:pine tanninhexamine(TH)and organosolv lignin non-isocyanate polyurethane(NIPU),suitable for interior nonstructural use,were compared with commercial urea-formaldehyde(UF)*** in chemical structure before and after the curing process were observed with Fouriertransform infrared spectroscopy(FTIR).The process of adhesive curing was monitored with differential scanning calorimetry(DSC)and the automated bonding evaluation system(ABES).Both DSC and ABES measurements confirmed UF as the fastest and NIPU as the slowest curing adhesive *** into account the ABES results,the optimal pressing parameters for the TH adhesive would be 4 min at 175℃,for the NIPU adhesive 7 min at 200℃and for the UF 1.5 min at 100℃.Strong linear correlation was observed between mechanical and chemical curing for the UF and NIPU adhesives,whereas lower correlation was observed for the TH *** all observed adhesives,the DSC measurements were underestimating the curing process determined by ABES in the first part and overestimating it at the *** underestimation was the most evident with the TH adhesive and the less with the UF *** comparing the uncured and cured FTIR spectra of all three types of adhesives,a drastic decrease in the characteristic band of-OH groups at 3330–3400 cm^(−1)and an increase in the signal intensity at 2920 cm^(−1)of aliphatic-CH2-groups were *** the UF adhesive,the C=O stretching frequency has shifted from 1632 cm^(−1)for uncured to three different bands at 1766,1701,and 1655 cm^(−1)for cured *** sharp band for phenolic alcohols at 1236 cm^(−1)of C–O stretch and hydroxyl O–H functional group at 1009 cm^(−1)and at 684 cm^(−1)of uncured TH adhesive diminished during curing,which indicates that a crosslinking reaction occurs via-OH *** peak of the C=O group of urethane bridges at 1697 cm^(−1)for uncured NIPU shifted to lower wavenumber at 1633 cm^(−1)for cured NIPU.

关键词： Biobased adhesives curing kinetics tannin lignin ABES DSC FTIR

A gameproblemofpursuit-evasionwith nth orderdifferentialequations describing players’dynamics

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Journal of Control and Decision 2022年第2期9卷 193-201页

作者： Abbas ja'afaru Badakaya Aminu Sulaiman Halliru jamilu Adamu Mathematial Sciences Bayero UniversityKanoNigeria Mathematics Federal University GashuaGashuaNigeria

In this paper,we study a pursuit-evasion differential game problem in the Hilbert space *** of countable number of pursuers and evader expressed as nth-order differential equa-tions with geometric constraints on the control functions of the *** game terminates at a given fixed time which is denoted by *** game's payoff is the infimum of the distances between the evader and pursuers at the time *** to the rule of the game,pursuers try to minimise the distance to the evader and the evader tries to maximises *** found value of the game and constructed players'optimal strategies.

关键词： Pursuit-evasion value of the game geometric constraints Hilbert space