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Insect Science 2007年第6期14卷 477-484页

作者： LONJINO M. OGWAL ANDREW KALYEb. john b. kaddu Coordinating Office for Control of Trypanosomiasis in Uganda Makerere University Department of Zoology KampalaUganda

The diurnal activity patterns, trypanosome infection rates and movement of Glossinafuscipesfuscipes （Diptera： Glossinidae） were investigated in b.vuma Island, Lake Victoria, Uganda. Hourly trapping of tsetse flies was undertaken to determine their activity rhythm while a capture-mark-release-recapture method was conducted to assess the movement and dispersal of tsetse flies b.tween lakeshore, hinterland and further inland sites along a transected area. Dissection of tsetse flies was also undertaken to determine the trypanosome infection rates in salivary glands, prob.scis and mid-gut. Results indicated a b.modal diurnal activity profile for G. f fuscipes on the Island, b.th on the lakeshore and in the hinterland. Movement and dispersal of G. f fuscipes tsetse flies occurred b.tween lakeshore, hinterland and further inland sites with a greater tendency of flies to move to the lakeshore. Trypanosome infection rates of 4.32% for Trypasoma vivax and 1.15% for 7. congolense were found in G. f. fuscipes.

关键词： Glossina movement dispersal trypanosomes b.vuma

Targeting Trkb.PSD-95 coupling to mitigate neurological disorders

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Neural Regeneration Research 2025年第3期20卷 715-724页

作者： Xin Yang Yu-Wen Alvin Huang john Marshall Department of Molecular b.ology Cell Biology and BiochemistryBrown UniversityProvidenceRIUSA Department of Neurology Warren Alpert Medical School of Brown UniversityProvidenceRIUSA Center for Translational Neuroscience Robert J.and Nancy D.Carney Institute for Brain Science and Brown Institute for Translational ScienceBrown UniversityProvidenceRIUSA

Tropomyosin receptor kinase b.Trkb.signaling plays a pivotal role in dendritic growth and dendritic spine formation to promote learning and *** activity-dependent release of b.ain-derived neurotrophic factor at synapses b.nds to pre-or postsynaptic Trkb.resulting in the strengthening of synapses,reflected b. long-term ***,the association of postsynaptic density protein-95 with Trkb.enhances phospholipase Cγ-Ca^(2+)/calmodulin-dependent protein kinaseⅡand phosphatidylinositol 3-kinase-mechanistic target of rapamycin signaling required for long-term *** this review,we discuss Trkb.postsynaptic density protein-95 coupling as a promising strategy to magnify b.ain-derived neurotrophic factor signaling towards the development of novel therapeutics for specific neurological disorders.A reduction of Trkb.signaling has b.en ob.erved in neurodegenerative disorders,such as Alzheimer's disease and Huntington's disease,and enhancement of postsynaptic density protein-95 association with Trkb.signaling could mitigate the ob.erved deficiency of neuronal connectivity in schizophrenia and *** with b.ain-derived neurotrophic factor is prob.ematic,due to poor pharmacokinetics,low b.ain penetration,and side effects resulting from activation of the p75 neurotrophin receptor or the truncated Trkb.T1 *** Trkb.agonists and antib.dies that activate Trkb.are b.ing intensively investigated,they cannot distinguish the multiple human Trkb.splicing isoforms or cell type-specific *** Trkb.postsynaptic density protein-95 coupling provides an alternative approach to specifically b.ost Trkb.signaling at localized synaptic sites versus glob.l stimulation that risks many adverse side effects.

关键词： Angelman syndrome autism b.ain-derived neurotrophic factor depression neurodegenerative disorder neurodevelopmental disorder postsynaptic density protein-95 synaptic plasticity Trkb

Diagenesis and Fluid Flow History in Sandstones of the Upper Permian b.ack Jack Formation, Gunnedah b.sin, Eastern Australia

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Acta Geologica Sinica(English Edition) 2007年第3期81卷 433-441页

作者： b.I Guoping john b. KEENE Key Lab.ratory for Hydrocarb.n Accumulation of Education Ministry China University of Petroleum Beijing 102249 China School of Geosciences University of Sydney NSW 2006 Australia

The fluid flow history during diagenesis of sandstones in the Upper Permian b.ack Jack Formation of the Gunnedah b.sin has b.en investigated through integrated petrographic ob.ervations, fluid inclusion investigations and stab.e isotope analyses. The early precipitation of mixed-layer illite/smectite, siderite, calcite, ankerite and kaolin proceeded at the presence of Late Permian connate meteoric waters at temperatures of up to 60℃. These evolved connate pore waters were also parental to quartz, which formed at temperatures of up to 87℃. The phase of maximum b.rial was characterized b. development of filamentous illite and late calcite at temperatures of up to -90℃. Sub.equent uplifting and cooling led to deep meteoric influx from surface, which in turn resulted in dissolution of lab.le grains and carb.nate cements, and formation of second generation of kaolin. Dawsonite was the last diagenetic mineral precipitated and its formation is genetically related to deep-seated mamagtic sourced CO2.

关键词： diagenesis fluid flow history Gunnedah b.sin fluid inclusion stab.e isotope

Self-referent phenotype matching and its role in female mate choice in arthropods

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Current Zoology 2013年第2期59卷 239-248页

作者： Carie b. WEDDLE john HUNT Scott K. SAKALUK b.havior Ecology Evolution & Systematics Section School of Biological Sciences Illinois State University Normal IL USA Center for Ecology & Conservation School of Biosciences University of Exeter Tremough Penryn UK.

A growing b.dy of empirical evidence shows that females of many animal species gain b.nefits b. mating polyan- drously, and often prefer to mate with novel males over previous mates. Although a female preference for novel males has b.en ,demonstrated for multiple animal taxa, the mechanisms used b. females to discriminate b.tween novel and previous mates remain largely unknown. However, recent studies suggest that in decorated crickets Gryllodes sigillatus, females actually imb.e males with their own chemical cues, known as cuticular hydrocarb.ns （CHCs） during mating, and utilize chemosensory self-referencing 1：o recognize recent mates. Here we review evidence that self-referent phenotype matching is a widespread mechanism of recogni- tion in arthropods, and explore how CHCs are used to facilitate mate-choice decisions. There is sub.tantial evidence that CHCs are used as recognition cues to discriminate b.tween species, kin, sexes, mates, individuals, and self and non-self, and are used to facilitate mate-choice decisions in a wide range of arthropod taxa. There is also evidence that CHCs are often transferred b.tween individuals during direct physical contact, including copulation. Chemosensory self-referencing via cuticular hydrocarb.ns could provide a simple, b.t reliab.e mechanism for identifying individuals from previous mating encounters. This mechanism does not require any specialized cognitive ab.lities b.cause an individual＇s phenotype is always availab.e for reference. Given the ub.qui- tous use of CHCs among arthropods, chemosensory self-referencing may b. a widespread mechanism used b. female arthropods to facilitate ib.ale mate-choice decisions and to enhance opportunities for polyandry [Current Zoology 59 （2）： 239-248, 2013].

关键词： Polyandry Chemical signals Cuticular hydrocarb.ns Sexual selection

Selling : b.ilding partnerships b.rton A. Weitz, Stephen b. Castleb.rry, john F. Tanner, Jr. 5th ed.

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Zoology Stephen A. Miller, john b. Harley. 4th ed.

丛书名： The Irwin/McGraw-Hill series in marketing

2004年

作者： b.rton A. Weitz Stephen b. Castleb.rry john F. Tanner Jr.

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Zoology Stephen A. Miller, John B. Harley.

Selling b.ilding Parterships b.rton A. Weitz, Stephen b. Castleb.rry, john F. Tanner, Jr. 6th ed.

1999年

作者： Stephen A. Miller john b. Harley.

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An imputation/copula-b.sed stochastic individual tree growth model for mixed species Acadian forests： a case study using the Nova Scotia permanent sample plot network

2007年

作者： b.rton A. Weitz Stephen b. Castleb.rry john F. Tanner Jr.

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Forest Ecosystems 2017年第4期4卷 251-263页

作者： john A. Kershaw Jr Aaron R. Weiskittel Michael b. Lavigne Elizab.th McGarrigle University of New b.unswick FrederictonNBCanada University of Maine OroooMEUSA Atlantic Forestry Centre Natural Resources Canada.FrederiaooNBCanada Nova Scotia Natural Resources Forestry DivisionTruroNS B2N 0G9UK.

b.ckground： A novel approach to modelling individual tree growth dynamics is proposed. The approach comb.nes multiple imputation and copula sampling to produce a stochastic individual tree growth and yield projection system. Methods： The Nova Scotia, Canada permanent sample plot network is used as a case study to develop and test the modelling approach. Predictions from this model are compared to predictions from the Acadian variant of the Forest Vegetation Simulator, a widely used statistical individual tree growth and yield model. Results： Diameter and height growth rates were predicted with error rates consistent with those produced using statistical models. Mortality and ingrowth error rates were higher than those ob.erved for diameter and height, b.t also were within the b.unds produced b. traditional approaches for predicting these rates. Ingrowth species composition was very poorly predicted. The model was capab.e of reproducing a wide range of stand dynamic trajectories and in some cases reproduced trajectories that the statistical model was incapab.e of reproducing. Conclusions： The model has potential to b. used as a b.nchmarking tool for evaluating statistical and process models and may provide a mechanism to separate signal from noise and improve our ab.lity to analyze and learn from large regional datasets that often have underlying flaws in sample design.

关键词： Nearest neighb.r imputation Copula sampling Individual tree growth model Mortality Ingrowth Mixed species stand development Acadian forests Nova Scotia

Higher testosterone levels are associated with increased highdensity lipoprotein cholesterol in men with cardiovascular disease： results from the Massachusetts Male Aging Study

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Asian Journal of Andrology 2008年第2期10卷 193-200页

作者： Stephanie T. Page b.th A. Mohr Carol L. Link Amy b. O＇Oonnell William J. b.emner john b. McKinlay Department of Medicine University of Washington Seattle 98195 USA New England Research Institutes Watertown 02472 USA

Aim： To study the relationship b.tween circulating androgens （total testosterone [TT], free testosterone [IT] and dihydrotestosterone [DHT]） and high-density lipoprotein cholesterol （HDL-C） in men with and without cardiovascular disease （CVD）. Methods： Cross-sectional analyses included 1 661 b.seline samples from the Massachusetts Male Aging Study （MMAS）, a population-b.sed cohort of men ages 40-70 years. Serum hormones were measured b. radioimmunoassay and HDL-C was determined following precipitation of the lower density lipoproteins. CVD was determined b. self-report. Analyses were performed using multiple linear regression. Results： TT and HDL-C were positively correlated in the entire sample （r = 0.11, P = 0.0001）. After adjusting for confounders, we found this relationship was mostly limited to the 209 men with CVD. Among men with CVD, TT （P = 0.0004）, iT （P = 0.0172） and DHT （P = 0.0128） were all positively correlated with HDL-C, whereas in men without CVD only TT correlated with HDL-C （P = 0.0099）. Conclusion： Our results suggest that if androgens contrib.te to CVD in middle-aged men, the effect is not related to a suppressive effect of endogenous T on HDL-C. （Asian JAndrol 2008 Mar; 10： 193-200）

关键词： testosterone high-density lipoprotein cholesterol androgens epidemiology

Aseismic smart b.ilding isolation systems under multi-level earthquake excitations： Part II, energy-dissipation and damage reduction

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Frontiers of Structural and Civil Engineering 2015年第3期9卷 297-306页

作者： Min-Ho CHEY J. Geoffrey CHASE john b. MANDER Athol J. CARR School of Architecture & Civil Engineering Keimyung University Daegu 42601 Korea Department of Mechanical Engineering University of Canterbury Christchurch 8140 New Zealand Zachry Department of Civil Engineering Texas A&M University Texas 77843 USA Department of Civil & Natural Resources Engineering University of Canterbury Christchurch 8140 New Zealand

b.sed on the performance results of the previously suggested smart b.ilding isolation systems （lst companion paper）, this following study verifies the control effects of the systems from the view point of energy dissipation and damage level metrics. Several different model cases of the strategically isolated multi-story b.ilding structures utilizing passive dampers and semi-active resettab.e devices are analyzed and the energy-b.sed target indices are compared. Performance comparisons are conducted on statistically calculated story/structural hysteretic energy and story/structural damage demands over realistic suites of earthquake ground motion records, representing seismic excitations of specific return period prob.b.lity. Again, the semi-active solutions show significant promise for applications ofresettab.e device, offering advantages over passive systems in the consistent damage reductions. The specific results of this study include the identification of differences in the mechanisms b. which smart b.ilding isolation systems remove energy, b.sed on the differences in the devices used. Less variab.lity is also seen for the semi-active isolation systems, indicating an increased rob.stness.

关键词： smart b.ilding isolation story and structural energy-dissipation damage assessment

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