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卡特彼勒的ABM

新理财（公司理财） 2014年第11期 75-78页

作者： David G.DeFreitas john W.Gillett ross L.Fink Whitney Cox

以作业成本管理（ABM）寻求精益之道,是巨头卡特彼勒成功的有效方法。还记得2008～2009年的经济衰退吗？对于季度财务工作者而言,似乎那场衰退已经相当遥远。然而,对于卡特彼勒的人而言就完全是另外一回事了。要在最恶劣的经济环境中存... 详细信息

以作业成本管理（ABM）寻求精益之道,是巨头卡特彼勒成功的有效方法。还记得2008～2009年的经济衰退吗？对于季度财务工作者而言,似乎那场衰退已经相当遥远。然而,对于卡特彼勒的人而言就完全是另外一回事了。要在最恶劣的经济环境中存活下来,企业不论规模大小都应当致力于消除业务运营中方方面面的浪费情况。

关键词：卡特 ABM 作业成本管理 2009年财务工作者经济衰退经济环境业务运营

Two new species of caddisflies from East Asia （Trichoptera： Philopotamidae, Psychomyiidae）

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Insect Science 2006年第3期13卷 217-220页

作者： JUN MI HUR john C. MORSE Department of Entomology Soils and Plant Sciences Clemson University Clemson South Carolina USA

A new species of Kisaura ross （Philopotamidae） from Japan and a new species of Psychomyia Latreille （Psychomyiidae） from Russia are described. Kisaura imparis n. sp. is closest to Kisaura aurascens （Martynov, 1934）, but the lateral processes of tergum X are asymmetrical and the apex of tergum X is different. Psychomyia poltavkaensis n. sp. resembles Psychomyia n. sp., but the shape of tergum IX＋X is more rounded, the apex of the basoventral process of each preanal appendage is unforked, and the inferior appendages are branched.

关键词： Japan Kisaffra,Philopotamidae Psychomyia Psychomyiidae Russia

Treatment with analgesics after mouse sciatic nerve injury does not alter expression of wound healingassociated genes

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Neural Regeneration Research 2016年第1期11卷 144-149页

作者： Matt C.Danzi Dario Motti Donna L.Avison john L.Bixby Vance P.Lemmon The Miami Project to Cure Paralysis University of MiamiLois Pope LIFE Center Department of Surgery Leonard M. Miller School of Medicine University of Miami Department of Neurological Surgery University of Miami Department of Molecular and Cellular Pharmacology University of Miami

Animal models of sciatic nerve injury are commonly used to study neuropathic pain as well as axon regeneration. Administration of post-surgical analgesics is an important consideration for animal welfare, but the actions of the analgesic must not interfere with the scientific goals of the experiment. In this study, we show that treatment with either buprenorphine or acetaminophen following a bilateral sciatic nerve crush surgery does not alter the expression in dorsal root ganglion（DRG） sensory neurons of a panel of genes associated with wound healing. These findings indicate that the post-operative use of buprenorphine or acetaminophen at doses commonly suggested by Institutional Animal Care and Use Committees does not change the intrinsic gene expression response of DRG neurons to a sciatic nerve crush injury, for many wound healing-associated genes. Therefore, administration of post-operative analgesics may not confound the results of transcriptomic studies employing this injury model.

关键词： acetaminophen analgesics axon buprenorphine dorsal root ganglia gene expression peripheral nerve injuries regeneration sciatic nerve wound healing

Clinical outcomes of patients with two small hepatocellular carcinomas

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World Journal of Hepatology 2021年第10期13卷 1439-1449页

作者： Anh Duy Pham Karl Vaz Zaid S Ardalan Marie Sinclair ross Apostolov Sarah Gardner Ammar Majeed Gauri Mishra Ning Mao Kam Kurvi Patwala Numan Kutaiba Niranjan Arachchi Sally Bell Anouk T Dev john S Lubel Amanda J Nicoll Siddharth Sood William Kemp Stuart K Roberts Michael Fink Adam G Testro Peter W Angus Paul J Gow The Victorian Liver Transplant Unit Austin HealthHeidelberg 3084VictoriaAustralia Department of Gastroenterology Alfred HealthMelbourne 3000VictoriaAustralia The Melbourne Liver Group Melbourne 3000VictoriaAustralia The University of Melbourne Parkville 3010VictoriaAustralia Central Clinical School Monash UniversityMelbourne 3004VictoriaAustralia Department of Gastroenterology and Hepatology Monash HealthClayton 3168VictoriaAustralia Department of Radiology Austin HealthHeidelberg 3084VictoriaAustralia Department of Radiology Eastern HealthBox Hill 3128VictoriaAustralia Department of Gastroenterology Western HealthFootscray 3011VictoriaAustralia Department of Gastroenterology Eastern HealthBox Hill 3128VictoriaAustralia Department of Gastroenterology Royal Melbourne HospitalParkville 3050VictoriaAustralia

BACKGROUND Management of single small hepatocellular carcinoma(HCC)is straightforward with curative outcomes achieved by locoregional therapy or *** transplantation is often considered for multiple small or single large *** of two small HCC whether presenting synchronously or sequentially is less *** To define the outcomes of patients presenting with two small *** Retrospective review of HCC databases from multiple institutions of patients with either two synchronous or sequential HCC≤3 cm between January 2000 and March *** outcomes were overall survival(OS)and transplant-free survival(TFS).RESULTS 104 patients were identified(male n=89).Median age was 63 years(interquartile range 58-67.75)and the most common aetiology of liver disease was hepatitis C(40.4%).59(56.7%)had synchronous HCC and 45(43.3%)had sequential.36 patients died(34.6%)and 25 were transplanted(24.0%).1,3 and 5-year OS was 93.0%,66.1% and 62.3% and 5-year post-transplant survival was 95.8%.1,3 and 5-year TFS was 82.1%,45.85% and 37.8%.When synchronous and sequential groups were compared,OS(1,3 and 5 year synchronous 91.3%,63.8%,61.1%,sequential 95.3%,69.5%,64.6%,P=0.41)was similar but TFS was higher in the sequential group(1,3 and 5 year synchronous 68.5%,37.3% and 29.7%,sequential 93.2%,56.6%,48.5%,P=0.02)though this difference did not remain during multivariate *** TFS in patients presenting with two HCC≤3 cm is poor regardless of the timing of the second *** patients presenting with two small HCC should be considered for transplantation.

关键词： Hepatocellular carcinoma Liver cancer Prognosis Transplantation Transplant-free survival

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非梗阻型和梗阻型肥厚性心肌病

国际心血管病杂志 1980年第4期 208-222页

作者： ross J 麻世迹

john ross:这一临床讨论会的主要目的,着重于阐述当前普遍承认的一种心脏病——肥厚性心肌病的诊断和治疗进展。认识本病大约只有15年。在这一期间,本病的命名以及病理生理学曾引起许多争论。尽管如此,关于肥厚性心肌病在心脏病范畴中... 详细信息

john ross:这一临床讨论会的主要目的,着重于阐述当前普遍承认的一种心脏病——肥厚性心肌病的诊断和治疗进展。认识本病大约只有15年。在这一期间,本病的命名以及病理生理学曾引起许多争论。尽管如此,关于肥厚性心肌病在心脏病范畴中的地位,目前相对地已很清楚。可以认为,它的地位相当于其他的一些心脏疾病,诸如冠心病、瓣膜病(二尖瓣狭窄、二尖瓣关闭不全、先天性和获得性主动脉瓣狭窄)、乳头肌功能不全、二尖瓣脱垂综合征、先天性心脏病以及其它原发性和继发性心肌病等。肥厚性心肌病

关键词：肥厚性心肌病患者 HCM 梗阻型压力阶差收缩期杂音室间隔厚超声心动图检查二尖瓣关闭不全二尖瓣闭锁不全流出道

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Terra硝酸铵工厂爆炸事故调查及教训

Terra硝酸铵工厂爆炸事故调查及教训

1983～1998年间加拿大不列颠哥伦比亚海岸大蓝鹭(Ardea herodias)卵内多氯二苯并-p-二恶英(PCDDs)和二苯并呋喃(PCDFs)的时空趋势监测

2006流体机械与压力容器技术论坛

作者： Brad McGoran Bernard ross Sudhir Nunes Christopher Buehler Ali Reza Abid Kemal john Fessler Jacques Belanger David Arnold 毅博失效分析咨询公司毅博失效分析咨询公司毅博失效分析咨询公司毅博失效分析咨询公司毅博失效分析咨询公司毅博失效分析咨询公司毅博失效分析咨询公司毅博失效分析咨询公司密西西比化工集团

1994年,Terra化学工业公司位于伊阿华州的一家硝酸铵工厂发生了两起重大的爆炸事故,造成重大伤亡和财产损失。毅博失效分析咨询公司负责调查了这起事件,分析了工厂的可靠性生产数据,同时进行了大量有关于硝酸铵性质和分解机制的实验。... 详细信息

1994年,Terra化学工业公司位于伊阿华州的一家硝酸铵工厂发生了两起重大的爆炸事故,造成重大伤亡和财产损失。毅博失效分析咨询公司负责调查了这起事件,分析了工厂的可靠性生产数据,同时进行了大量有关于硝酸铵性质和分解机制的实验。调查表明爆炸事件是由包括缺乏设备维护和员工培训在内的非安全生产操作所造成的。包括政府机构和专家在内的多方人士都对毅博公司的事故调查表示认同,同时也就此达成了一项数百万美元的诉讼协议。

关键词：硝酸铵中和容器失效分析

来源： cnki会议评论

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AMBIO－人类环境杂志 2001年第7期30卷 416-427页

作者： john E. Elliott Megan L. Harris Laurie K. Wilson Philip E. Whitehead ross J. Norstrom 李康民加拿大野生动物保护机构 Lorax Environmental 196 Spencer Rd.RD5 Lake TaraweraRotorua New Zealand

从1983～1998年,沿加拿大不列颠哥伦比亚海岸,我们监测了21处大蓝鹭(Ardea herodias)结巢处卵内多氯二苯并-p-二恶英(PCDDs)、二苯并呋喃(PCDFs)和多氯联苯(PCBs)的污染情况。20世纪90年代早期,主要的同类物如1,2,3,7,8-PnCDD、1,2,3,6,... 详细信息

从1983～1998年,沿加拿大不列颠哥伦比亚海岸,我们监测了21处大蓝鹭(Ardea herodias)结巢处卵内多氯二苯并-p-二恶英(PCDDs)、二苯并呋喃(PCDFs)和多氯联苯(PCBs)的污染情况。20世纪90年代早期,主要的同类物如1,2,3,7,8-PnCDD、1,2,3,6,7,8-HxCDD、2,3,7,8-TCDD、2,3,7,8-TCDF、1,2,3,7,8,9-HxCDD和2,3,4,7,8-PnCDF在纸浆厂分子氯漂白技术被新的漂白技术替代以及氯基酚类木材保存剂和抗木材变色剂的使用被严格地限制之后有显著下降。被捕食的鱼与大蓝鹭卵内污染物水平之间的强正线性回归说明,每天在本地摄食的食物是大蓝鹭暴露于污染物的一个重要路径。从1985年到1991年,在某些栖居地的大蓝鹭卵内所测到的毒当量浓度(TEQs)足以在小鹭体内产生胚胎毒性。尽管PCDD/Fs有所减少,但估计整个80年代有些城市中苍鹭栖居地的毒当量浓度由于多氯联苯的作用而居高不下。

关键词： 1983-1998年加拿大不列颠哥伦比亚海岸大蓝鹭多氯二苯并-p-二恶英二苯并呋喃趋势监测鸟卵动物监测海洋监测

Multiple quantitative trait loci contribute to resistance to bacterial canker incited by Pseudomonas syringae *** in kiwifruit(Actinidia chinensis)

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Horticulture Research 2019年第1期6卷 471-488页

作者： Jibran Tahir Stephen Hoyte Heather Bassett Cyril Brendolise Abhishek Chatterjee Kerry Templeton Cecilia Deng ross Crowhurst Mirco Montefiori Ed Morgan Andrew Wotton Keith Funnell Claudia Wiedow Mareike Knaebel Duncan Hedderley Joel Vanneste john McCallum Kirsten Hoeata Amardeep Nath David Chagné Luis Gea Susan E.Gardiner The New Zealand Institute for Plant and Food Research Limited Private Bag 11030Manawatu Mail CentrePalmerston North 4442New Zealand The New Zealand Institute for Plant Food Research Limited HamiltonNew Zealand The New Zealand Institute for Plant and Food Research Limited Private Bag 92–169Auckland 1025New Zealand New Plant via Malpighi 5Forlì47122Italy The New Zealand Institute for Plant and Food Research Limited LincolnNew Zealand The New Zealand Institute for Plant and Food Research Limited 412 No 1 RoadRD2Te Puke 3182New Zealand

Pseudomonas syringae ***(Psa)biovar 3,a virulent,canker-inducing pathogen is an economic threat to the kiwifruit(Actinidia spp.)industry *** commercially grown diploid(2×)*** *** is more susceptible to Psa than tetraploid and hexaploid *** information on the genetic loci modulating Psa resistance in kiwifruit is not *** we report mapping of quantitative trait loci(QTLs)regulating resistance to Psa in a diploid kiwifruit population,derived from a cross between an elite Psa-susceptible‘Hort16A’and a resistant male breeding parent *** high-density genetic maps and intensive phenotyping,we identified a single QTL for Psa resistance on Linkage Group(LG)27 of‘Hort16A’revealing 16–19%phenotypic variance and candidate alleles for susceptibility and resistance at this *** addition,six minor QTLs were identified in P1 on distinct LGs,exerting 4–9%*** in the F1 population is improved by additive effects from‘Hort16A’and P1 QTLs providing evidence that divergent genetic pathways interact to combat the virulent Psa *** different bioassays further identified new QTLs for tissue-specific responses to *** genetic marker at LG27 QTL was further verified for association with Psa resistance in diploid Actinidia chinensis *** analysis of Psa-resistant and susceptible genotypes in field revealed hallmarks of basal defense and provided candidate RNA-biomarkers for screening for Psa resistance in greenhouse conditions.

关键词： breeding trait

Overview of genetic signaling pathway interactions within cutaneous malignancies

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Journal of Cancer Metastasis and Treatment 2020年第1期6卷 440-479页

作者： Brittany S.Maner Leonie Dupuis Ashley Su Jeremy J Jueng Tanner P.Harding john Meisenheimer Ⅶ Fahad S.Siddiqui Mia R.Hardack Savina Aneja James A.Solomon ross University School of Medicine MiramarFL 33027USA Ameriderm Research Ormond BeachFL 32174USA University of Central Florida College of Medicine OrlandoFL 32827USA University of South Florida Morsani College of Medicine TampaFL 33612USA Alabama College of Osteopathic Medicine DothanAL 36303USA Advanced Dermatology and Cosmetic Surgery OrlandoFL 32806USA Florida State University College of Medicine OrlandoFL 32304USA Kansas City University of Medicine&Biosciences Kansas CityMO 64106USA Carle-Illinois College of Medicine UrbanaIL 61820USA

Melanoma and non-melanoma cutaneous malignancies are some of the leading causes of cancer-related death in the United *** melanoma is more known to have a high mortality rate,the total mortality per year is nearly equal for between melanoma and non-melanoma skin ***,the non-melanoma types of cutaneous malignancies have potential to become locally invasive and even metastasize with very little to no treatment options when *** development of these malignancies involves various genetic pathways through the four hallmarks of cancer development:malignant cell growth,apoptosis evasion,the use of supporting stroma and vascularization,and modulating and promoting an inadequate immune *** genetic signaling pathways of basal cell carcinoma,squamous cell carcinoma,verrucous carcinoma,basosquamous cell carcinoma,melanoma,and cutaneous T-cell lymphoma interact with each other through genetic predisposition as well as with environmental ***,solar ultraviolet radiation and chronic inflammatory states are found to initiate the progression of many of these cutaneous *** paper includes validated models of genetic pathways,emerging pathways,and crosstalk between genetic pathways through the four hallmarks of cancer ***,unlike most reviews addressing oncogenetics of the well-recognized,as well as newly discovered,genetic pathway mutations,this review stresses that these pathways are not fixed but rather exist in dynamic,interrelated,interactive,complex,and adaptive flux states.

关键词： Basal cell carcinoma squamous cell carcinoma verrucous carcinoma basosquamous cell carcinoma melanoma cutaneous T-cell lymphoma genetic pathways cancer hallmarks