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Nanoscale mapping of optically inaccessible bound-states-in-the-continuum

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Light(Science & Applications) 2022年第2期11卷 188-196页

作者： Zhaogang Dong Zackaria Mahfoud Ramón Paniagua-Domínguez Hongtao wang Antonio I.Fernández-Domínguez Sergey Gorelik Son Tung Ha Febiana Tjiptoharsono Arseniy I.kuznetsov Michel Bosman joel k.w.yang Institute of Materials Research and Engineering A*STAR(Agency for ScienceTechnology and Research)2 Fusionopolis Way#08-03 Innovis138634 SingaporeSingapore Department of Materials Science and Engineering National University of Singapore9 Engineering Drive 1117575 SingaporeSingapore Singapore University of Technology and Design 8 Somapah Road487372 SingaporeSingapore Departamento de Física Teórica de la Materia Condensada and Condensed Matter Physics Center Universidad Autónoma de Madrid28049 MadridSpain Singapore Institute of Food and Biotechnology Innovation A*STAR(Agency for ScienceTechnology and Research)31 Biopolis Way#01-02 Nanos138669 SingaporeSingapore

Bound-states-in-the-continuum(BIC)is an emerging concept in nanophotonics with potential impact in applications,such as hyperspectral imaging,mirror-less lasing,and nonlinear harmonic *** true BIC modes are nonradiative,they cannot be excited by using propagating light to investigate their optical *** this paper,for the 1st time,we map out the strong near-field localization of the true BIC resonance on arrays of silicon nanoantennas,via electron energy loss spectroscopy with a sub-1-nm electron *** systematically breaking the designed antenna symmetry,emissive quasi-BIC resonances become *** gives a unique experimental tool to determine the coherent interaction length,which we show to require at least six neighboring antenna *** importantly,we demonstrate that quasi-BIC resonances are able to enhance localized light emission via the Purcell effect by at least 60 times,as compared to unpatterned *** work is expected to enable practical applications of designed,ultra-compact BIC antennas such as for the controlled,localized excitation of quantum emitters.

关键词： antenna states mapping

Fabrication of opaque and transparent 3D structures using a single material via twophoton polymerisation lithography

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Light(Advanced Manufacturing) 2023年第3期4卷 243-250页

作者： Parvathi Nair Suseela Nair Chengfeng Pan Hao wang Deepshikha Arora Qing yang Steve wu M.A.Rahman Jinghua Teng joel k.w.yang Institute of Materials Research and Engineering(IMRE) Agency for ScienceTechnology and Research(A*STAR)#08-03 Innovis2 Fusionopolis Way138634Singapore Singapore University of Technology and Design 8 Somapah RoadSingapore 487372

Two-photon polymerisation lithography enables the three-dimensional(3D)-printing of high-resolution micron-and nano-scale *** that are 3D-printed using proprietary resins are transparent and are suitable as optical ***,achieving a mix of opaque and transparent structures in a single optical component is challenging and requires multiple material systems or the manual introduction of ink after *** this study,we investigated an overexposure printing process for laser decomposition,which typically produces uncontrollable and random‘burnt’***,we present a printing strategy to control this decomposition process,realising the on-demand printing of opaque or transparent structures in a single lithographic step using a single *** this method,opaque structures can be printed with a minimum feature size of approximately 10μm,which exhibitkness of approximately 30μ*** applied this process to print an opaque aperture integrated with a transparent lens to demonstrate an improved imaging contrast.

关键词： 3D printing Two-photon polymerisation lithography Optically opaque Laser decomposition Lens imaging contrast

Stepwise-Nanocavity-Assisted Transmissive Color Filter Array Microprints

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Research 2018年第1期2018卷 34-43页

作者： Yasi wang Mengjie Zheng Qifeng Ruan Yanming Zhou Yiqin Chen Peng Dai Zhengmei yang Zihao Lin Yuxiang Long Ying Li Na Liu Cheng-wei Qiu joel k.w.yang Huigao Duan State key Laboratory of Advanced Design and Manufacturing for Vehicle Body College of Mechanical and Vehicle EngineeringHunan UniversityChangsha 410082China School of Physics and Electronics Hunan UniversityChangsha 410082China SZU-NUS Collaborative Innovation Center for Optoelectronic Science&Technology International Collaborative Laboratory of 2D Materials for Optoelectronics Science and Technology of Ministry of EducationCollege of Optoelectronic EngineeringShenzhen UniversityShenzhen 518060China Department of Electrical and Computer Engineering National University of Singapore4 Engineering Drive 3Singapore 117583Singapore Engineering Product Development Pillar Singapore University of Technology and Design8 Somapah RoadSingapore 487372Singapore kirchhof Institute for Physics University of HeidelbergIm Neuenheimer Feld 22769120 HeidelbergGermany

Visible-light color flters using patterned nanostructures have attracted much interest due to their various advantages such as compactness,enhanced stability,and environmental friendliness compared with traditional pigment or dye-based optical *** most existing studies are based on planar nanostructures with lateral variation in size,shape,and arrangement,the vertical dimension of structures is a long-ignored degree of freedom for the structural ***,we demonstrate a synthetic platform for transmissive color flter array by coordinated manipulations between height-varying nanocavities and their lateral flling *** thickness variation of those nanocavities has been fully deployed as an alternative degree of freedom,yielding vivid colors with wide gamut and excellent *** results show that the color-rendering capability of the pixelated nanocavities can be still retained as pixels are miniaturized to 500 *** between closely spaced pixels of a Bayer color flter arrangement was calculated,showing minimal crosstalk for 1μm2 square *** work provides an approach to designing and fabricating ultracompact color flter arrays for various potential applications including stained-glass microprints,microspectrometers,and high-resolution image sensing systems.

关键词： arrangement rendering cavity

High-throughput fabrication of large-scale metasurfaces using electron-beam lithography with SU-8 gratings for multilevel security printing

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Photonics Research 2023年第3期11卷 I0040-I0047页

作者： YOU SIN TAN HAO wANG HONGTAO wANG CHENGFENG PAN joel k.w.yang Singapore University of Technology and Design 487372 SingaporeSingapore Institute of Materials Research and Engineering A*STAR(Agency for ScienceTechnology and Research)138634 SingaporeSingapore

The field of metasurface research has rapidly developed in the past ***-beam lithography(EBL)is an excellent tool used for rapid prototyping of ***,Gaussian-beam EBL generally struggles with low *** conjunction with the recent rise of interest in metasurfaces made of low-index dielectric materials,we propose in this study the use of a relatively unexplored chemically amplified resist,SU-8 with EBL,as a method for rapid prototyping of low-index *** demonstrate the use of SU-8 grating on silicon for cost-efficient fabrication of an all-dielectric multilevel security print for anti-counterfeiting purposes,which encrypt different optical information with different light illumination conditions,namely,bright-field reflection,dark-field reflection,and cross-polarized *** large-scale print(1 mm^(2))could be exposed in a relatively short time(~11 min)due to the ultrahigh sensitivity of the resist,while the feature size of~200 nm was maintained,demonstrating that SU-8 EBL resist serves as a good candidate for rapid prototyping of metasurface *** results could find applications in the general area of increasing EBL patterning speed for a variety of other devices and structures.

关键词： lithography beam dielectric

Coevolution of nanophotonics and nanofabrication:achievements and beyond

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Photonics Insights 2024年第4期3卷 3-4页

作者： Hongtao wang joel k.w.yang Engineering Product Development Singapore University of Technology and DesignSingapore

Recent advancements in nanofabrication techniques,coupled with innovative nanostructure designs,have unveiled intriguing possibilities for the manipulation of *** capabilities encompass control over fundamental properties of light,including phase,amplitude,polarization,directional propagation,frequency conversion,chirality,and angular momentum of *** plasmonic nanostructures,which are often constrained by their inherent ohmic losses,dielectric metasurfaces,constructed from materials like titanium dioxide(TiO_(2)),silicon,and gallium nitride,offer low-loss and high-index alternatives^([1–3]).This distinction allows for the development of more efficient and versatile optical devices^([2–6]),including lenses,holograms,structural color filters,and sensing platforms.

关键词： versatile dioxide titanium

Human endogenous retrovirus type-w and multiple sclerosis–related smoldering neuroinflammation

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Neural Regeneration Research 2025年第3期20卷 813-814页

作者： joel Gruchot Laura Reiche Andrew Chan Robert Hoepner Patrick küry Department of Neurology Medical Faculty and University Hospital DüsseldorfHeinrich Heine University DüsseldorfDüsseldorfGermany Department of Neurology InselspitalBern University Hospital and University of BernBernSwitzerland

Introduction to human endogenous retrovirus type-w(HERV-w): Genomic inheritance from the past includes retroviral sequences that have been stably incorporated into our genomes and account for up to 8% of human DNA.

关键词： endogenous inflammation Human

State of machine and deep learning in histopathological applications in digestive diseases

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world Journal of Gastroenterology 2021年第20期27卷 2545-2575页

作者： Soma kobayashi joel H Saltz Vincent w yang Department of Biomedical Informatics Renaissance School of MedicineStony Brook UniversityStony BrookNY 11794United States Department of Medicine Renaissance School of MedicineStony Brook UniversityStony BrookNY 11794United States Department of Physiology and Biophysics Renaissance School of MedicineStony Brook UniversityStony BrookNY 11794United States

Machine learning(ML)-and deep learning(DL)-based imaging modalities have exhibited the capacity to handle extremely high dimensional data for a number of computer vision *** these approaches have been applied to numerous data types,this capacity can be especially leveraged by application on histopathological images,which capture cellular and structural features with their highresolution,microscopic ***,these methodologies have demonstrated promising performance in a variety of applications like disease classification,cancer grading,structure and cellular localizations,and prognostic predictions.A wide range of pathologies requiring histopathological evaluation exist in gastroenterology and hepatology,indicating these as disciplines highly targetable for integration of these *** have also already been primed to consider the impact of these algorithms,as development of real-time endoscopic video analysis software has been an active and popular field of *** heightened clinical awareness will likely be important for future integration of these methods and to drive interdisciplinary collaborations on emerging *** provide an overview on the application of these methodologies for gastrointestinal and hepatological histopathological slides,this review will discuss general ML and DL concepts,introduce recent and emerging literature using these methods,and cover challenges moving forward to further advance the field.

关键词： Artificial intelligence Machine learning Deep learning Gastroenterology Hepatology Histopathology

3D printed fiber sockets for plug and play micro-optics

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International Journal of Extreme Manufacturing 2021年第1期3卷 122-129页

作者： Parvathi S Nair Jonathan Trisno Hongtao wang joel k.w.yang Singapore University of Technology and Design 8 Somapah Road487372Singapore Institute of Materials Research and Engineering(IMRE) A^(∗)STAR138634Singapore

Integrating micro-optical components at the end facet of an optical fiber enables compact optics to shape the output beam(***,focusing,and coupling to free space elements or photonic integrated circuits).However,the scalability of this approach is a longstanding challenge as these components must be aligned onto individual fiber *** this paper,we propose a socket that enables easy slotting of fibers,self-alignment,and coupling onto micro-optical *** integrated socket can be detached from the substrate upon fiber insertion to create a stand-alone optical *** is done using nanoscale 3D printing via two-photon polymerization lithography onto glass substrates,which allows multiple sockets to be patterned in a single *** investigated variations in socket design and evaluated the performance of optical elements for telecom *** obtained an alignment accuracy of∼3.5μ*** socket designs can be customized for high efficiency chip to fiber coupling and extended to other spectral ranges for free-form optics.

关键词： integrated socket alignment fiber slotting fiber connector two-photon polymerization lithography

Esophagogastric junction distensibility assessed using the functional lumen imaging probe

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world Journal of Gastroenterology 2017年第7期23卷 1289-1297页

作者： Joan w Chen joel H Rubenstein Department of Gastro-enterology and Hepatology University of Michigan Health SystemsAnn ArborMI 48109United States

To assess reference values in the literature for esophageal distensibility and cross-sectional area in healthy and diseased subjects measured by the functional lumen imaging probe (FLIP).METHODSSystematic search and review of articles in Medline and Embase pertaining to the use of FLIP in the esophagus was conducted in accordance with the PRISMA guidelines. Cross-sectional area and distensibility at the esophagogastric junction (EGJ) were abstracted for normal subjects, achalasia, and gastroesophageal reflux disease (GERD) patients, stratified by balloon length and volume of *** achalasia studies (n = 154), 3 GERD (n = 52), and 5 studies including healthy controls (n = 98) were included in the systematic review. Normative data varied widely amongst studies of healthy volunteers. In contrast, studies in achalasia patients uniformly demonstrated low point estimates in distensibility ≤ 1.6 mm2/mmHg prior to treatment that increased to ≥ 3.4 mm2/mmHg following treatment at 40mL bag volume. In GERD patients, distensibility fell to the range of untreated achalasia (≤ 2.85 mm2/mmHg) following *** may be a useful tool in assessment of treatment efficacy in achalasia. The drastic drop in EGJ distensibility after fundoplication suggests that FLIP measurements need to be interpreted in the context of esophageal body motility and highlights the importance of pre-operative screening for dysmotility. Future studies using standardized FLIP protocol and balloon size are needed.

关键词： Impedance planimetry Gastroesophageal reflux disease Esophageal distensibility Achalasia