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The Twisted Homology of Simplicial Set

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Acta Mathematica Sinica,English Series 2022年第10期38卷 1781-1802页

作者： Meng Meng ZHANG jing yan li Jie WU School of Mathematical Sciences Hebei Normal UniversityShijiazhuang 050024P.R.China yanqi Lake Beijing Institute of Mathematical Sciences and Applications Beijing 101408P.R.China

In this article,we give a generalization of δ-twisted homology introduced by jingyan li,Vladimir Vershinin and Jie Wu,called Δ-twisted homology,which enriches the theory of δ-(co)homology introduced by Alexander Grigor’yan,Yuri Muranov and Shing-Tung *** show that the Mayer-Vietoris sequence theorem holds for Δ-twisted *** the Δ-twisted ideas to Cartesian products,we introduce the notion of Δ-twisted Cartesian product on simplicial sets,which generalizes the classical work of Barratt,Gugenheim and Moore on twisted Cartesian products of simplicial *** certain hypothesis,we show that the coordinate projection of Δ-twisted Cartesian product admits a fibre bundle structure.

关键词： Simplicial set Δ-Twisted homology Homotopy type Fibre bundle

Structural engineering of Sb-based electrode materials to enhance advanced sodium-ion batteries

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Rare Metals 2024年第10期43卷 4777-4806页

作者： Zheng yang Qiao-ling Kang Rui-Wang li-jing yan Xian-He Meng Ting-li Ma College of Materials and Chemistry Jiliang UniversityHangzhou 310018China

Antimony(Sb)is recognized as a potential electrode material for sodium-ion batteries(SIBs)due to its huge reserves,affordability,and high theoretical capacity(660 mAh·g^(-1)).However,Sb-based materials experience significant volume expansion during cycling,leading to comminution of the active substance and limiting their practical use in ***,the volume expansion issue of Sb-based materials during charging/discharging must be solved to create high-performance *** paper presents a detailed review of structural engineering of Sb-based electrode materials,focusing on the performance effects of different kinds of structures on advanced performance ***,the future development and the challenges of Sb-based materials are *** paper can provide specific perspectives on the structure construction and optimization of Sb-based anode materials so as to promote the rapid development and practical applications of SIBs.

关键词： Sb-based electrode Sodium-ion batteries Structural engineering

H pylori stimulates proliferation of gastric cancer cells through activating mitogen-activated protein kinase cascade

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World Journal of Gastroenterology 2006年第37期12卷 5972-5977页

作者： Yong-Chang Chen Ying Wang jing-yan li Wen-Rong Xu You-li Zhang School of Medicine Jiangsu University Zhenjiang Jiangsu Province China School of Medical Technology Jiangsu University Zhenjiang Jiangsu Province China Affiliated Hospital of Jiangsu University Zhenj iang Jiangsu Province China

AIM: To explore the mechanism by which H pylori causes activation of gastric epithelial cells. METHODS: A VacA (+) and CagA (+) standard H pylori line NCTC 11637 and a human gastric adenocarcinoma derived gastric epithelial cell line BGC-823 were applied in the study. MTT assay and 3H-TdR incorporation test were used to detect the proliferation of BGC-823 cells and Western blotting was used to detect the activity and existence of related proteins. RESULTS: Incubation with H pylori extract increased the proliferation of gastric epithelial cells, reflected by both live cell number and DNA synthesis rate. The activity of extracellular signal-regulated protein kinase (ERK) signal transduction cascade increased within 20 min after in- cubation with H pylori extract and appeared to be a sus- tained event. MAPK/ERK kinase (MEK) inhibitor PD98059 abolished the action of H pylori extract on both ERK activity and cell proliferation. Incubation with H pylori extract increased c-Fos expression and SRE-dependent gene expression. H pylori extract caused phosphorylation of several proteins including a protein with molecular size of 97.4 kDa and tyrosine kinase inhibitor genistein inhibited the activation of ERK and the proliferation of cells caused by H pylori extract. CONCLUSION: Biologically active elements in H pylori extract cause proliferation of gastric epithelial cells through activating tyrosine kinase and ERK signal trans- duction cascade.

关键词： H pylori Gastric cancer cells Proliferation Mitogen-activated protein kinase

Ubiquitiformal Crack Extension in Quasi-Brittle Materials

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Acta Mechanica Solida Sinica 2020年第5期33卷 674-691页

作者： Zhuo-Cheng Ou Yi-Bo Ju jing-yan li Zhuo-Ping Duan Feng-Lei Huang State Key Laboratory of Explosion Science and Technology School of MechatronicsBeijing Institute of TechnologyBeijing100081China

Based on the concept of ubiquitiform,a ubiquitiformal crack extension model is developed for quasi-brittle *** simulations are carried out using the ABAQUS software with the XFEM-based cohesive segments method to determine the ubiquitiformal crack extension path or fracture surface profile of the material under quasi-static *** a ubiquitiformal crack model removes the singularity of a fractal crack;for the latter,the boundary value problem cannot be uniquely *** the simulation,the material properties,e.g.,the tensile strength,are assumed to obey the Weibull *** meso-element equivalent method is used to determine the correlation between the Weibull distribution parameters and the aggregate gradation of concrete *** numerical results show that the complexities of the ubiquitiformal crack configurations are in good agreement with the previous experimental *** the numerical simulation,it is further demonstrated that the complexity of a ubiquitiformal crack is insensitive to the random spatial distribution of the aggregates,but more dependent on the Weibull distribution parameters which reflect the heterogeneity of the concrete.

关键词： Ubiquitiformal crack Complexity Quasi-brittle materials Random distribution of tensile strength Weibull distribution parameters

Pseudo-random sequence generator based on the generalized Henon map

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The Journal of China Universities of Posts and Telecommunications 2008年第3期15卷 64-68页

作者： ZHENG Fan TIAN Xiao-jian SONG jing-yi li Xue-yan College of Electronic Science and Engineering Jilin University Changchun 130012 China

By analysis and comparison of several chaotic systems that are applied to generate pseudo-random sequence, the generalized Henon map is proposed as a pseudo-random sequence generator. A new algorithm is created to solve the problem of non-uniform distribution of the sequence generated by the generalized Henon map. First, move the decimal point of elements in the sequence to the fight; then, cut off the integer; and finally, quantify it into a binary sequence. Statistical test, security analysis, and the application of image encryption have strongly supported the good random statistical characteristics, high linear complexity, large key space, and great sensitivity of the binary sequence.

关键词： pseudo-random sequence chaos the generalized Henon map

Nuclear fragile X mental retardation-interacting protein 1-mediated ribophagy protects T lymphocytes against apoptosis in sepsis

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Burns & Trauma 2023年第1期11卷 72-90页

作者： Peng-Yue Zhao Ren-Qi Yao li-Yu Zheng Yao Wu Yu-Xuan li Ning Dong jing-yan li Xiao-Hui Du Yong-Ming Yao Translational Medicine Research Center Medical Innovation Research Division and Fourth Medical Center of the Chinese PLA General HospitalBeijing 100853China Department of General Surgery First Medical Center of the Chinese PLA General HospitalBeijing 100853China Department of Burn Surgery The First Affiliated Hospital of Naval Medical UniversityShanghai 200433China Department of Emergency The Second Hospital of Hebei Medical UniversityShijiazhuang 050000China

Background:Ribophagy is a selective autophagic process that specifically degrades dysfunctional or superfluous ribosomes to maintain cellular *** ribophagy can ameliorate the immunosuppression in sepsis similar to endoplasmic reticulum autophagy(ERphagy)and mitophagy remains *** study was conducted to investigate the activity and regulation of ribophagy in sepsis and to further explore the potential mechanism underlying the involvement of ribophagy in T-lymphocyte ***:The activity and regulation of nuclear fragile X mental retardation-interacting protein 1(NUFIP1)-mediated ribophagy in T lymphocytes during sepsis were first investigated by western blotting,laser confocal microscopy and transmission electron ***,we constructed lentivirally transfected cells and gene-defective mouse models to observe the impact of NUFIP1 deletion on T-lymphocyte apoptosis and finally explored the signaling pathway associated with T-cell mediated immune response following septic ***:Both cecal ligation and perforation-induced sepsis and lipopolysaccharide stimulation significantly induced the occurrence of ribophagy,which peaked at 24 *** NUFIP1 was knocked down,T-lymphocyte apoptosis was noticeably ***,the overexpression of NUFIP1 exerted a significant protective impact on T-lymphocyte ***,the apoptosis and immunosuppression of T lymphocytes and 1-week mortality rate in NUFIP1 gene-deficient mice were significantly increased compared with those in wild-type *** addition,the protective effect of NUFIP1-mediated ribophagy on T lymphocytes was identified to be closely related to the endoplasmic reticulum stress apoptosis pathway,and PERK-ATF4-CHOP signaling was obviously involved in downregulating T-lymphocyte apoptosis in the setting of ***:NUFIP1-mediated ribophagy can be significantly activated to alleviate T lymphocyte apoptosis through the PERK-ATF4-CHOP pathway

关键词： NUFIP1 Ribophagy Sepsis Apoptosis Immunosuppression Autophagy Mitophagy Lymphocyte lipopolysaccharide

Correlates of Condom-use Self-efficacy on the EPPM-based Integrated Model among Chinese College Students

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Biomedical and Environmental Sciences 2017年第2期30卷 97-105页

作者： JIN Shan Shan BU Kai CHEN Fang Fang XU Hui Fang li Yi ZHAO Dong Hui XU Fang li jing yan HAN Meng Jie WANG Ning WANG Lu National Center for AIDS/STD Control and Prevention Chinese Center for Disease Control and PreventionBeijing 102206China Guangzhou Center for Disease Control and Prevention Guangzhou 510440GuangdongChina Heilongjiang Provineial Center for Disease Control and Prevention Harbin 150030HeilongjiangChina Tianjin University of Traditional Chinese Medicine Tianjin 300193China lingnan Partners Community Support Center Guangzhou 510000GuangdongChina

Objective To explore the predictors of condom-use self-efficacy in Chinese college students according to the extended parallel process model （EPPM）-based integrated model. Methods A total of 3,082 college students were anonymously surveyed through self-administered questionnaires in Guangzhou and Harbin, China. A structural equation model was applied to assess the integrated model. Results Among the participants, 2,387 （46.7%） were male, 2,586 （53.3%） were female, and the average age was 18.6 years. The final integrated model was acceptable. Apart from the direct effect （r = 0.23）, perceived severity had two indirect effects on condom-use self-efficacy through the attitude to HIV education （r = 0.40） and intention to engage in premarital sex （r = -0.16）, respectively. However, the perceived susceptibility mediated through the intention to engage in premarital sex （intent-to-premarital-sex） had a poor indirect impact on condom-use self-efficacy （total effect was -0.06）. Furthermore, attitude toward HIV health education （r = 0.49） and intent-to-premarital-sex （r = -0.32） had a strong direct effect on condom-use self-efficacy. In addition, male students perceived higher susceptibility, stronger intent-to-premarital-sex, and lower condom-use self-efficacy than female students. Conclusion The integrated model may be used to assess the determinants of condom-use self-efficacy among Chinese college students. Future research should focus on raising the severity perception, HIV-risk-reduction motivation, and the premarital abstinence intention among college students. Furthermore, considering the gender differences observed in the present survey, single-sex HIV education is required in school-based HIV/sex intervention.

关键词： HIV infection Condom-use self-efficacy Chinese college students

Effect of Cl^-ion on Anodic Iron Dissolution in H_2S-Containing Sulfuric Acid Solutions

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Chinese Chemical Letters 1998年第10期9卷 945-948页

作者： li jing yan lin NIU Hat Chao liN Wei Tao WU Shang Zhang liU(Institute of Corrosion and Protection of Metals, State Key Laboratory for Corrosion and Protection, Chinese Academy of Sciences, Shenyang 110015Department of Chemistry, liaoning University, S Inst. Corros. and Protect. of Met. State Key Lab. Corros. and Protect. Chinese Academy of Sciences Shenyang 110015 China Department of Chemistry Liaoning University Shenyang 110036 China

The effect of Cl- ion on the anodic iron dissolution in H2SO4 solutions containing H2S has been studied by using electrochemical polarization curve measurements. The competitive adsorption for Cl- and HS- ions at an anodic potential has been calculated using the CNDO/2method. The results show that a ceftain concentration of the Cl- ion can be adsorbed steadily and inhibit the anodic reaction of iron catalyzed by HS-. However, when the Cl- ion reaches the saturation adsorption, it begins to promote the anodic reaction of iron due tO the increased negative charge of iron atoms.

关键词： iron anodic dissolution Cl H_2S, CNDO/2

miRNA-21-5p is an important contributor to the promotion of injured peripheral nerve regeneration using hypoxia-pretreated bone marrow-derived neural crest cells

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Neural Regeneration Research 2025年第1期20卷 277-290页

作者： Meng Cong jing-jing Hu yan Yu Xiao-li li Xiao-Ting Sun li-Ting Wang Xia Wu ling-Jie Zhu Xiao-Jia yang Qian-Ru He Fei Ding Hai-yan Shi School of Medicine Nantong UniversityNantongJiangsu ProvinceChina Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education and Coinnovation Center of Neuroregeneration Nantong UniversityNantongJiangsu ProvinceChina Department of Physiology Jiangsu Health Vocational CollegeNanjingJiangsu ProvinceChina Department of Pathology Affiliated Hospital of Nantong UniversityNantongJiangsu ProvinceChina Jiangsu Clinical Medicine Center of Tissue Engineering and Nerve Injury Repair Affiliated Hospital of Nantong UniversityNantongJiangsu ProvinceChina

Our previous study found that rat bone marrow–derived neural crest cells(acting as Schwann cell progenitors)have the potential to promote long-distance nerve ***-based therapy can enhance peripheral nerve repair and regeneration through paracrine bioactive factors and intercellular ***,the complex contributions of various types of soluble cytokines and extracellular vesicle cargos to the secretome remain *** investigate the role of the secretome and extracellular vesicles in repairing damaged peripheral nerves,we collected conditioned culture medium from hypoxia-pretreated neural crest cells,and found that it significantly promoted the repair of sensory neurons damaged by oxygen-glucose *** mRNA expression of trophic factors was highly expressed in hypoxia-pretreated neural crest *** performed RNA sequencing and bioinformatics analysis and found that miR-21-5p was enriched in hypoxia-pretreated extracellular vesicles of neural crest ***,to further clarify the role of hypoxia-pretreated neural crest cell extracellular vesicles rich in miR-21-5p in axonal growth and regeneration of sensory neurons,we used a microfluidic axonal dissociation model of sensory neurons in vitro,and found that hypoxia-pretreated neural crest cell extracellular vesicles promoted axonal growth and regeneration of sensory neurons,which was greatly dependent on loaded ***,we constructed a miR-21-5p-loaded neural conduit to repair the sciatic nerve defect in rats and found that the motor and sensory functions of injured rat hind limb,as well as muscle tissue morphology of the hind limbs,were obviously *** findings suggest that hypoxia-pretreated neural crest extracellular vesicles are natural nanoparticles rich in ***-21-5p is one of the main contributors to promoting nerve regeneration by the neural crest cell *** helps to explain the mechanism of action of the secretome and e

关键词： axotomy cell-free therapy conditioned medium extracellular vesicles hypoxic preconditioning microRNA oxygen-glucose deprivation peripheral nerve injury Schwann cell precursors