检索结果-南通市图书馆

在线全文

学校读者我要写书评

暂无评论

成人特发性膜性肾病临床病理特征及预后分析

临床肾脏病杂志 2024年第7期24卷 543-549页

作者：史美萍金钟大广州中医药大学第二临床医学院广州510000 广东省中医院肾内科广州510000

目的探讨成人特发性膜性肾病(idiopathic membranous nephropathy,IMN)的临床病理特征及预后,分析IMN肾脏结局的影响因素。方法收集2012年1月至2023年6月于广东省中医院肾病中心就诊,首次经肾活检确诊为IMN的646例患者的临床和病理资料... 详细信息

目的探讨成人特发性膜性肾病(idiopathic membranous nephropathy,IMN)的临床病理特征及预后,分析IMN肾脏结局的影响因素。方法收集2012年1月至2023年6月于广东省中医院肾病中心就诊,首次经肾活检确诊为IMN的646例患者的临床和病理资料进行回顾性分析,采用Cox比例风险模型和Kaplan-Meier生存曲线对截止至2023年12月随访时间≥6个月的486例患者进行生存分析。结果(1)646例IMN患者中,男女比例为1.33∶1,≥40岁患者521例(80.7%),病理分期以Ⅱ期为主(472例,73.1%),肾小球球性硬化387例(59.9%),节段性硬化99例(15.3%),肾小管间质病变554例(85.8%),肾小血管病变540例(83.6%)。(2)单因素Cox回归结果显示,年龄、血肌酐、血尿酸、高血压、三酰甘油、24 h尿蛋白定量、球性硬化、节段性硬化、肾小管间质病变是肾脏预后不良的危险因素,而估算肾小球滤过率、血浆白蛋白、血红蛋白是肾脏结局的保护因素,多因素校正后只有年龄是肾脏预后不良的独立危险因素(HR=1.042,95%CI:1.015~1.069,P=0.002)。(3)Kaplan-Meier生存曲线分析结果显示,中度、重度球性硬化组患者肾脏生存率低于无球性硬化组和轻度球性硬化组(P<0.05);节段性硬化组患者肾脏生存率显著低于无节段性硬化组(P<0.001);中重度肾小管间质病变组患者肾脏生存率显著低于无间质病变组(P=0.001)和轻度间质病变组(P=0.001)。结论IMN好发于中老年人群,中度和重度肾小球球性硬化、节段性硬化以及中重度肾小管间质病变IMN患者肾脏生存率降低,但只有年龄能作为肾脏结局的独立预测因子。

关键词：特发性膜性肾病病理特征生存分析

Solar Cells Based on All-Inorganic Halide Perovskites:Progress and Prospects

在线全文

学校读者我要写书评

暂无评论

Transactions of Nanjing University of Aeronautics and Astronautics 2018年第4期35卷 648-655页

作者： Ni Chenwei Tie Zuoxiu jin zhong Key Laboratory of Mesoscopic Chemistry of MOE School of Chemistry and Chemical EngineeringNanjing University

The emergence of perovskite solar cells(PSCs)based on all-inorganic metal halide(IMH)has generated enormous interest in the photovoltaic research community,and the power conversion efficiency(PCE)has exceeded13%.Despite its outstanding performance in thermal stability,PSCs based on IMH still face problems such as the lack of a suitable band gap and the inability to generate large *** this review,we will summarize the latest progress of PSCs based on IMH.

关键词： perovskite solar cells all-inorganic metal halide thermal stability

Memory,Time and Technique Aspects of Density Matrix Renormalization Group Method

在线全文

学校读者我要写书评

暂无评论

Communications in Theoretical Physics 2001年第11期36卷 635-640页

作者： QIN Shao-jin LOU Ji-zhong Department of Physics Kyushu University6-10-1 HakozakiHigashi-kuFukuoka 812-8581Japan Institute of Theoretical Physics P.O.Box 2735Beijing 100080China Department of PhysicsUniversity of NevadaLas VegasNV 89154USA

We present the memory size,computational time,and technique aspects of density matrix renormalization group (DMRG) *** show how to estimate the memory size and computational time before starting a large scale DMRG *** propose an implementation of the Hamiltonian wavefunction multiplication and a wavefunction initialization in DMRG with block matrix data ***-dimensional Heisenberg model is used to illustrate our study.

关键词： density matrix renormalization group,one-dimensional antiferromagnetic Heisenberg model

Skin Microbiome： An Actor in the Pathogenesis of Psoriasis

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Medical Journal 2018年第1期131卷 95-98页

作者： Wen-Ming Wang Hong-zhong jin Department of Dermatology Peking Union Medical College Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100730 China

INTRODUCTION Psoriasis is characterized by raised, scaly, well-demarcated, erythematous oval plaques. Although studies have revealed that disruption of immune tolerance and excessive production of inflammatory factors play important roles in the pathogenesis of psoriasis, the exact mechanism is still not clear Previous studies have shown that the concordance rate of monozygotic twins with psoriasis is greater than that of dizygotic twins, with genetic thctors underpinning 66-90% of the variation in risk of developing psoriasis.

关键词： Inflammatory Diseases: Psoriasis Skin Microbiome

Topological Entropy of a Class of Subshifts of Finite Type

在线全文

学校读者我要写书评

暂无评论

Acta Mathematica Sinica,English Series 2018年第12期34卷 1765-1777页

作者： jin zhong XU Lan Yu WANG Key Laboratory of Space Utilization Technology and Engineering Center for Space Utilization Chinese Academy of Sciences Beijing 100094 P. R. China University of Chinese Academy of Sciences Beijing 100049 P. R. China Academy of Mathematics and Systems Science Chinese Academy of Sciences Beijing 100190 P. R. China

In this paper, we construct a special class of subshifts of finite type. By studying the spectral radius of the transfer matrix associated with the subshift of finite type, we obtain an estimation of its topological entropy. Interestingly, we find that the topological entropy of this class of subshifts of finite type converges monotonically to log（n ＋ 1）（a constant only depends on the structure of the transfer matrices） as the increasing of the order of the transfer matrices.

关键词： Symbolic dynamical system subshift of finite type topological entropy transfer matrix,Toeplitz matrix

omocysteine： A Potential Common Route for Cardiovascular Risk and DNA Methylation in Psoriasis

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2017年第16期130卷 1980-1986页

作者： Wen-Ming Wang Hong-zhong jin Department of Dermatology Peking Union Medical College Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100730 China

Objective： Homocysteine is a sulfur-containing amino acid with potential clinical significance. Abnormal homocysteine levels have been found in patients with psoriasis. This review summarizes the possible correlations among homocysteine, cardiovascular risk, and DNA methylation in psoriasis. Data Sources： We retrieved the articles published in English from the PubMed database up to January 2017, using the keywords including ＂psoriasis,＂＂homocysteine,＂＂cardiovascular risk,＂＂DNA methylation,＂＂methylenetetrahydrofolate reductase,＂＂MTHFR,＂ and ＂MTHFR C677T.＂ Study Selection： Articles about the roles of homocysteine in the cardiovascular risk and DNA methylation in psoriasis were obtained and reviewed. Results： Observational studies consistently reported that elevated homocysteine is an independent risk factor for cardiovascular diseases. Several studies also consistently reported an association between psoriasis and increased cardiovascular risk. A substantial body of evidence also suggested that an elevated homocysteine level is related to the demethylation of DNA. Data from clinical trials also demonstrated that MTHFR C677T polymorphisms as well as DNA methylation aberrations are associated with psoriasis. Conclusions： This review highlighted the relationships among homocysteine, cardiovascular risk, and DNA methylation, suggesting that homocysteine may be a biological link between cardiovascular risk and DNA methylation in psoriasis.

关键词： Cardiovascular Disease DNA Methylation Homocysteine Psoriasis

在线全文

学校读者我要写书评

暂无评论

流化床中煤气化细渣高温还原磷石膏过程

化工进展 2024年第6期43卷 3479-3491页

作者：马栋解桂林田治华王勤辉张建国宋慧林钟晋浙江大学能源清洁利用国家重点实验室浙江杭州310027 云南云天化环保科技有限公司云南昆明650300

磷石膏(PG)是世界上重要的工业固体废物之一,其传统的储存方法占用了大片土地,也破坏了环境。采用热化学方法将PG还原为CaS和CaO不仅可以变废为宝,而且缓解了环境污染。常见的还原剂主要是褐煤和硫黄等,然而上述还原剂存在成本较高的缺... 详细信息

磷石膏(PG)是世界上重要的工业固体废物之一,其传统的储存方法占用了大片土地,也破坏了环境。采用热化学方法将PG还原为CaS和CaO不仅可以变废为宝,而且缓解了环境污染。常见的还原剂主要是褐煤和硫黄等,然而上述还原剂存在成本较高的缺点。因此本文提出采用煤气化细渣(CGFS)来还原PG。通过热力学计算、流化床实验和动力学计算,探讨了还原行为和反应机理。首先,热力学计算表明CGFS还原PG完全可行。流化床实验发现当目标产物为CaS时,最优化的反应条件为温度应保持在850~900℃,C/Ca摩尔比为2~3,在该条件下,PG可以完全分解。当目标产物为CaO时,温度应保持在950~1000℃,C/Ca摩尔比为0.5~1,但在该条件下PG难以完全分解。此外CGFS中的矿物组分会显著影响PG的分解率,该过程主要是和CGFS的反应活性有关。接着通过比较四种常见的碳基还原剂发现,褐煤对PG的分解效率最高,细渣和焦炭相比于石墨具有较高的反应活性,也有利于PG的分解过程。此外提高C/Ca摩尔比和反应温度能够降低石墨与其他三种还原剂的差距。最后动力学研究表明,CGFS还原PG过程符合缩核反应模型,其动力学机理函数G(α)=-ln(1-α),表观活化能为415.78~456.83kJ/mol。通过SEM-EDS发现反应是从边界开始,逐渐扩散到核心,最终形成蜂窝结构。本研究将为开发环境友好型还原剂分解PG提供理论依据。

关键词：磷石膏煤气化细渣动力学热力学分解机理

Effect of electropulsing on anisotropy behaviour of cold-rolled commercially pure titanium sheet

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

Transactions of Nonferrous Metals Society of China 2009年第S02期19卷 409-413页

作者： WANG zhong-jin SONG Hui School of Materials Science and Engineering Harbin Institute of TechnologyHarbin 150001China

The specimens cut from the cold-rolled pure titanium sheet at 0°,45°and 90°to the rolling direction were treated by high density electropulsing(maximum current density J=(7.22-7.96)×10^(3)A/mm^(2),pulse period t_(p)=110μs).The mechanical properties and microstructures of the cold-rolled,electropulsed and conventional annealed commercially pure titanium sheet were examined by using uniaxial tension test machine and optical microscope(OM),*** results show that the deformation behavior of the electropulsed pure titanium sheet is significantly different from that of conventional annealed pure titanium *** difference of the mechanical properties between the 0°,45°and 90°direction specimens is almost *** is mainly due to the increase in dislocation mobility and formation of lamellar microstructure after the electropulsing.

关键词： commercially pure titanium anisotropy lamellar microstructure electropulsing treatment

不同硅铝比和晶体粒径的ZSM-5分子筛的二甲苯异构化反应研究

在线全文

学校读者我要写书评

暂无评论

精细石油化工 2024年第3期41卷 19-25页

作者：拓鹏飞高宁宁高俊魁钟进王辉国中石化石油化工科学研究院有限公司北京100083

采用水热晶化法合成了不同硅铝比和晶体粒径的ZSM-5分子筛,采用X射线衍射(XRD)、X射线荧光光谱(XRF)、扫描电子显微镜(SEM)、氨气程序升温脱附(NH_(3)-TPD)、氮气物理吸附等进行物化性质表征,在固定床微反装置上进行二甲苯异构化反应性... 详细信息

采用水热晶化法合成了不同硅铝比和晶体粒径的ZSM-5分子筛,采用X射线衍射(XRD)、X射线荧光光谱(XRF)、扫描电子显微镜(SEM)、氨气程序升温脱附(NH_(3)-TPD)、氮气物理吸附等进行物化性质表征,在固定床微反装置上进行二甲苯异构化反应性能评价。结果表明,纳米ZSM-5分子筛呈聚集体形貌,晶体粒径为50~100 nm,聚集体尺寸随着硅铝比增加由约500 nm增大至约1μm。ZSM-5分子筛的硅铝比由32增加至127,其酸量由0.55 mmol/g逐渐降低至0.19 mmol/g,乙苯脱烷基及二甲苯分子间、乙苯与二甲苯的烷基转移反应活性均显著降低,二甲苯收率呈升高趋势;酸量为0.24~0.55 mmol/g时,二甲苯异构化活性稳定在24.08%~24.17%。减小ZSM-5分子筛晶体粒径有利于显著增加外表面积,从而获得更高的二甲苯异构化活性,但也会使降低二甲苯收率;不同晶体粒径的ZSM-5分子筛乙苯脱烷基反应性能变化不大。

关键词：芳烃脱烷基异构化二甲苯