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Risk factors and clinical significance of posterior slip of the proximal vertebral body after lower lumbar fusion

World Journal of Clinical Cases 2024年第26期12卷 5885-5892页

作者： Jia-jun Zhu Yi Wang jun Zheng Sheng-Yang Du Lei Cao Yu-Ming Yang Qing-xi Zhang Ding-Ding xie Department of Spinal Surgery Xuzhou First People’s HospitalXuzhou 221112Jiangsu ProvinceChina Department of Spinal Surgery The Affiliated Xuzhou Municipal Hospital of Xuzhou Medical UniversityXuzhou 221112Jiangsu ProvinceChina Department of Spinal Surgery The Affiliated Hospital of China University of Mining and TechnologyXuzhou 221112Jiangsu ProvinceChina

BACKGROUND Adjacent segment disease(ASD)after fusion surgery is frequently manifests as a cranial segment instability,disc herniation,spinal canal stenosis,spondylolisthesis or *** risk factors and mechanisms of ASD have been widely discussed but never clearly *** To investigate the risk factors and clinical significance of retrograde movement of the proximal vertebral body after lower lumbar *** This was a retrospective analysis of the clinical data of patients who underwent transforaminal lumbar interbody fusion surgery between September 2015 and July 2021 and who were followed up for more than 2 ***-one patients with degenerative lumbar diseases were included(22 males and 69 females),with an average age of 52.3 years(40-73 years).According to whether there was retrograde movement of the adjacent vertebral body on postoperative X-rays,the patients were divided into retrograde and nonretrograde *** sagittal parameters of the spine and pelvis were evaluated before surgery,after surgery,and at the final *** the same time,the Oswestry Disability Index(ODI)and Visual Analogue Scale(VAS)were used to evaluate the patients’quality of *** Nineteen patients(20.9%)who experienced retrograde movement of proximal adjacent segments were included in this *** pelvic incidence(PI)of the patients in the retrograde group were significantly higher than those of the patients in the nonretrograde group before surgery,after surgery and at the final follow-up(P<0.05).There was no significant difference in lumbar lordosis(LL)between the two groups before the operation,but LL in the retrograde group was significantly greater than that in the nonretrograde group postoperatively and at the final *** significant differences were detected in terms of the|PI–LL|,and there was no significant difference in the preoperative lordosis distribution index(LDI)between the two *** LDIs of the retrograde group were

关键词： Adjacent segment disease Posterior vertebral slip Sagittal alignment of spine-pelvis Lower lumbar fusion Quality of life

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Combined ATAC-seq,RNA-seq,and GWAS analysis reveals glycogen metabolism regulatory network in jinjiang oyster(Crassostrea ariakensis)

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Zoological Research 2024年第1期45卷 201-214页

作者： Biao Wu xi Chen Jie Hu Zhen-Yuan Wang Yan Wang Da-You Xu Hao-Bing Guo Chang-Wei Shao Li-Qing Zhou xiu-jun Sun Tao Yu xiao-Mei Wang Yan-xin Zheng Guang-Yi Fan Zhi-Hong Liu State Key Laboratory of Mariculture Biobreeding and Sustainable Goods Yellow Sea Fisheries Research InstituteChinese Academy of Fishery SciencesQingdaoShandong 266071China Laboratory for Marine Fisheries Science and Food Production Processes Laoshan LaboratoryQingdaoShandong 266071China BGI-Qingdao BGI-ShenzhenQingdaoShandong 266426China National Demonstration Center for Experimental Fisheries Science Education Shanghai Ocean UniversityShanghai 201306China Changdao Enhancement and Experiment Station Chinese Academy of Fishery SciencesYantaiShandong 265800China State Key Laboratory of Agricultural Genomics BGI-ShenzhenShenzhenGuangdong 518083China

Glycogen serves as the principal energy reserve for metabolic processes in aquatic shellfish and substantially contributes to the flavor and quality of *** jinjiang oyster(Crassostrea ariakensis)is an economically and ecologically important species in *** the present study,RNA sequencing(RNA-seq)and assay for transposase-accessible chromatin using sequencing(ATAC-seq)were performed to investigate gene expression and chromatin accessibility variations in oysters with different glycogen *** identified 9483 differentially expressed genes(DEGs)and 7215 genes with significantly differential chromatin accessibility(DCAGs)were obtained,with an overlap of 2600 genes between ***,a significant proportion of these genes were enriched in pathways related to glycogen metabolism,including“Glycogen metabolic process”and“Starch and sucrose metabolism”.In addition,genome-wide association study(GWAS)identified 526 single nucleotide polymorphism(SNP)loci associated with glycogen *** loci corresponded to 241 genes,63 of which were categorized as both DEGs and *** study enriches basic research data and provides insights into the molecular mechanisms underlying the regulation of glycogen metabolism in ***.

关键词： Crassostrea ariakensis Glycogen Transcriptome ATAC GWAS

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Application of prostate resectoscope in the treatment of massive rectal bleeding after transrectal prostate puncture

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World Journal of Clinical Cases 2024年第18期12卷 3438-3443页

作者： Hong-Mei Li Fa-Ying Yang Song Tu Peng Yan jun Qian Jia-xi Yao Department of Urology Hexi University Affiliated Zhangye People’s HospitalHexi UniversityZhangye 734000Gansu ProvinceChina Department of General Surgery II Hexi UniversityZhangye 734000Gansu ProvinceChina

BACKGROUND Ultrasound-guided prostate biopsy is a reliable diagnostic procedure for prostate cancer diagnosis with minimal procedure-related ***,complications,such as massive rectal bleeding may occur after the *** hypothesized that using a transrectal resectoscope could help treat massive rectal bleeding after transrectal prostate *** To identify a simple and effective treatment for massive rectal bleeding after transrectal prostate *** Patients requiring treatment for massive rectal bleeding after transrectal prostate punctures were included.A SIMAI resectoscope was inserted through the *** electrocoagulation was performed for superficial bleeding *** of the rectal mucosa or surface muscle layer was removed to expose deep bleeding points,followed by *** electric cutting ring was used to compress and stop the bleeding for jet-like points before *** fluid color in the drainage tube was monitored postoperatively for continuous *** Eight patients were included from 2012 to *** of the patients with massive rectal bleeding after the transrectal prostate punctures improved with conventional conservative and blood transfusion *** patients had an inferior artery embolism,and digital subtraction angiography was *** patients received emergency transanal prostate resection,which immediately stopped the *** days after the procedure,the patients had recovered and were *** Using a transanal prostate resection instrument is a simple,safe,and effective method for treating massive rectal bleeding after transrectal prostate punctures.

关键词： Electrocoagulation Hemostasis Transanal prostate resection instrumentation Prostate puncture

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Three-Channel Interference Interpretation of Fano Profile

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Chinese Physics Letters 2024年第5期41卷 30-34页

作者：李波李天钧马子茹王希源黄新朝朱林繁 Department of Modern Physics University of Science and Technology of ChinaHefei 230026China European XFEL Holzkoppel 422869 SchenefeldGermany

Fano resonance is a ubiquitous phenomenon, and it is commonly interpreted as a two-channel interference of the discrete and continuous channels. The present work investigates the Fano profile from a perspective of the temporal evolution of the wave function. By exciting the atom with a δ pulse and calculating the evolution of the wave function, the Fano formula is deduced. The results clearly show that the Fano resonance is of a three-channel interference, which is different from the traditional understanding. The three channels are revealed as the groundcontinuum, ground-discrete-continuum, and a previously unmentioned third channel, i.e., ground-continuumdiscrete-continuum. The present three-channel interpretation can be easily generalized to other physical systems,contributing to a deeper understanding of the Fano profile.

关键词： function profile continuum

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基于MLIR的数据流模型

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计算机工程与科学 2024年第7期46卷 1151-1157页

作者：李金熹尹首一魏少军胡杨清华大学集成电路学院北京100084

在冯诺依曼架构下,指令集的使用让软硬件得以解耦并各自飞速发展。然而,近年来并行多核架构加速器的热潮为冯诺依曼架构下的顺序编程模型带来了挑战。在顺序编程模型下设计而成的指令集缺乏对并行硬件的抽象,因此仅仅使用指令集已不能... 详细信息

在冯诺依曼架构下,指令集的使用让软硬件得以解耦并各自飞速发展。然而,近年来并行多核架构加速器的热潮为冯诺依曼架构下的顺序编程模型带来了挑战。在顺序编程模型下设计而成的指令集缺乏对并行硬件的抽象,因此仅仅使用指令集已不能完全完成软硬件的解耦。人工智能软件编译栈领域需要新的编程模型,以对接顺序执行的编程平台和并行多核的硬件后端,并进一步探索并行硬件提供的优化机会。使用数据流模型作为编程模型,为顺序执行程序和并行硬件指令集的对接过程提供通用抽象,在指令集的基础上进一步实现软件前端与硬件后端的解耦。为确保项目的可复用性,将数据流模型以codelet dialect的形式实现在谷歌提出的编译器框架MLIR上。MLIR致力于整合碎片化的编译器生态,提高前后端对接流程的可复用性,在MLIR上实现的数据流模型将进一步提升MLIR系统的可复用性。

关键词：数据流模型端到端编译 MLIR

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Hybrid Beamforming Design and Signal Processing with Fully-Connected Architecture for mmWave Integrated Sensing and Communications

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Journal of Communications and Information Networks 2024年第2期9卷 151-161页

作者： Hongyu Li jun Gong Wenchi Cheng The 54th Research Institute of China Electronics Technology Group Corporation Shijiazhuang 050080China State Key Laboratory of Integrated Services Networks Xidian UniversityXi’an 710071China

Millimeter-wave (mmWave) is capable of achieving gigabit/second communication capacity and centimeter-level sensing accuracy and has become one of the main frequency bands for integrated sensing and communications (ISAC) research. Hybrid beamforming techniques have attracted much attention for solving the high path loss of mmWave and further reducing the hardware cost of the system. However, the related studies based on multicarrier and fully-connected hybrid architectures are still limited. For this reason,this paper investigates the orthogonal frequency division multiplexing (OFDM) based mmWave fully-connected hybrid architecture ISAC system to form a stable communication beam and dynamically varying sensing beam. In order to realize the aforementioned multifunctional beams, the hybrid beamformer design problem based on weighted error minimization of multicarrier is proposed and solved efficiently using the penalty dual decomposition (PDD) algorithm. Meanwhile, based on the echo model, the multicarrier multiple signal classification (MUSIC) algorithm for target angle of arrival estimation and the two-dimensional discrete Fourier transform(2D-DFT)algorithm for distance and velocity estimation are proposed, respectively. Numerical simulation results show that by adjusting the weighting factor,a flexible trade-off can be formed between the communication spectrum efficiency and the sensing accuracy error.

关键词： integrated sensing and communications hybrid beamforming fully-connected architecture millimeter-wave

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Effect of surface modification on the radiation stability of diamond ohmic contacts

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Chinese Physics B 2024年第2期33卷 444-448页

作者：牟恋希赵上熳王鹏原晓芦刘金龙朱志甫陈良贤魏俊俊欧阳晓平李成明 Institute for Advanced Materials and Technology University of Science and Technology BeijingBeijing 100083China School of Mechanical Engineering University of Science and Technology BeijingBeijing 100083China School of Information Engineering Zhengzhou University of TechnologyZhengzhou 450044China State Key Laboratory of Intense Pulsed Radiation Simulation and Effect Northwest Institute of Nuclear TechnologyXi’an 710024China

The ohmic contact interface between diamond and metal is essential for the application of diamond *** modification can significantly affect the contact performance and eliminate the interface polarization ***,the radiation stability of a diamond detector is also sensitive to surface *** this work,the influence of surface modification technology on a diamond ohmic contact under high-energy radiation was *** radiation,the specific contact resistivities(ρc)between Ti/Pt/Au-hydrogen-terminated diamond(H-diamond)and Ti/Pt/Au-oxygenterminated diamond(O-diamond)were 2.0×10^(-4)W·cm^(2) and 4.3×10^(-3)Wcm^(2),*** 10 MeV electron radiation,the ρc of Ti/Pt/Au H-diamond and Ti/Pt/Au O-diamond were 5.3×10^(-3)W·cm^(2)and 9.1×10^(-3)W·cm^(2),*** rates of change of ρc of H-diamond and O-diamond after radiation were 2550%and 112%,*** electron radiation promotes bond reconstruction of the diamond surface,resulting in an increase in ρc.

关键词： single crystal diamond ohmic contact surface modification electron radiation

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Inhibitory effect of saffron on head and neck squamous cell carcinoma via targeting of ESR1 and CCND1 by its active compound crocetin

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Traditional Medicine Research 2024年第7期9卷 25-34页

作者： xiao-Jie Wang Ming-jun Zhang Li-Mei Cui Zhe-Ying Song Ya-Qi Wang Yu-Teng Yang xiang-Kun Zhao Ya-Kui Mou Yu-Mei Li xi-Cheng Song School of Clinical Medicine Weifang Medical UniversityWeifang 261042China. Department of Otorhinolaryngology Head and Neck SurgeryYantai Yuhuangding HospitalQingdao UniversityYantai 264000China. Shandong Provincial Clinical Research Center for Otorhinolaryngologic Diseases Yantai 264000China. Yantai Key Laboratory of Otorhinolaryngologic Diseases Yantai Yuhuangding HospitalYantai 264000China. The 2nd Medical College of Binzhou Medical University Yantai 264000China.

Background:Traditional Chinese medicine is promising for managing challenging and complex disorders,including cancer,and in particular,saffron is applied in treating various cancer ***,its potential therapeutic efficacy and active components in managing squamous cell carcinoma of the head and neck(HNSCC)remain unclear ***:Using network pharmacology approaches,active ingredients of saffron,their target genes,and HNSCC-related genes were *** analyses were conducted for determining molecular functions and pathways enriched by genes that overlapped between the saffron target gene set and the HNSCC gene *** the four known active ingredients of saffron,crocetin was found to have the strongest inhibitory impact on HNSCC,based on the findings of cell viability and migration ***,the potential target genes of crocetin in HNSCC cells were examined using molecular docking experiments and were confirmed by *** s:Four active ingredients of saffron and 184 of their target genes were ***,a total of 34 overlapping saffron-/HNSCC-associated targets related to the four active ingredients were screened,and crocetin was chosen for further investigation because it had the strongest inhibitory effect on HNSCC *** docking experiments indicated that ESR1 and CCND1 were the target genes of *** results were confirmed through qPCR analysis,in which crocetin was found to lower the expression of the ESR1 and CCND1 genes in AMC-HN-8 and FaDu ***:According to our results,crocetin is a primary active anti-cancer component of saffron that may have potential in the development of novel HNSCC-treating ***,more thorough molecular research is necessary for confirming these results and elucidating the anti-cancer mechanism underlying saffron.

关键词： saffron hub genes crocetin network pharmacology analysis HNSCC ESR1 CCND1

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Association of serum interleukin-6 with negative symptoms in stable early-onset schizophrenia

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World Journal of Psychiatry 2024年第6期14卷 794-803页

作者： Peng Chen Hai-Dong Yang jun-Jie Wang Zhen-Hua Zhu Hui-Min Zhao Xu-Yuan Yin Yuan Cai Hong-LiangZhu Jia-Lin Fu xin-Zhu Zhang Wen-xi Sun Li Hui xiao-Bin Zhang Suzhou Medical College of Soochow University Suzhou 215123Jiangsu ProvinceChina Department of Psychiatry Suzhou Psychiatric HospitalInstitute of Mental HealthThe Affiliated Guangji Hospital of Soochow UniversitySuzhou 215137Jiangsu ProvinceChina Department of Psychiatry The Fourth People’s Hospital of LianyungangThe Affiliated Kangda College of Nanjing Medical UniversityLianyungang 222003Jiangsu ProvinceChina Research Center of Biological Psychiatry Suzhou Psychiatric HospitalInstitute of Mental HealthThe Affiliated Guangji Hospital of Soochow UniversitySuzhou 215137Jiangsu ProvinceChina Department of Neurology The Affiliated Suzhou Hospital of Nanjing Medical UniversitySuzhou Municipal HospitalGusu SchoolNanjing Medical UniversitySuzhou 215002Jiangsu ProvinceChina

BACKGROUND Accumulating evidence suggests that the inflammatory cytokine interleukin-6(IL-6)contributes to the pathophysiology of psychiatric ***,there was no study concerning the relationship between IL-6 concentrations and clinical features in the chronic phase of early-onset schizophrenia(EOS).AIM To investigate the relationship between serum IL-6 concentration and the clinical features of *** We measured serum IL-6 Levels from 74 patients with chronic schizophrenia,including 33 with age at onset0.05)after controlling for age,body mass index,and other *** symptom scores were higher in the EOS group than the AOS group(F=6.199,P=0.015).Serum IL-6 concentrations in the EOS group were negatively correlated with both total PANSS-negative symptom score(r=-0.389,P=0.032)and avolition/asociality subscore(r=-0.387,P=0.026).CONCLUSION Patients with EOS may have more severe negative symptoms than those with adult-onset schizophrenia during the chronic phase of the ***-6 signaling may regulate negative symptoms and its avolition/asociality subsymptoms among the early-onset chronic schizophrenic patients.

关键词： Early-onset schizophrenia Interleukin 6 Negative symptoms Avolition Asociality

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数字经济发展对职业代际流动性的影响——中国式现代化背景下的公平考察视角

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现代财经（天津财经大学学报） 2024年第7期 23-41页

作者：彭骏赵西亮安徽财经大学经济学院安徽蚌埠233030 厦门大学经济学院福建厦门361005

中国式现代化是全体人民共同富裕的现代化。作为推进中国式现代化的重要动力,数字经济的发展能否改善社会公平,促进共同富裕目标的实现还有待深入探讨。本文将数字经济指数与2014—2018年中国家庭追踪调查(CFPS)数据相匹配,从公平视角... 详细信息

中国式现代化是全体人民共同富裕的现代化。作为推进中国式现代化的重要动力,数字经济的发展能否改善社会公平,促进共同富裕目标的实现还有待深入探讨。本文将数字经济指数与2014—2018年中国家庭追踪调查(CFPS)数据相匹配,从公平视角考察了我国数字经济发展对职业代际流动性的影响,并分析其作用机制。研究发现,数字经济发展显著提高了我国的职业代际流动性。影响机制分析表明,数字经济发展主要通过提高教育代际流动性、促进产业结构转型升级、发挥创新激励效应三条渠道提高职业代际流动性。进一步研究表明,数字经济发展对农村及城镇、内陆地区和沿海地区,以及高技能家庭和低技能家庭的职业代际流动性具有异质性影响。本文丰富了中国式现代化背景下关于数字经济社会公平效应的理论研究,也为如何畅通社会流动性以及推进共同富裕提供了政策支持。

关键词：中国式现代化数字经济职业代际流动性创新激励产业结构转型升级

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