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The association between C-reactive protein to albumin ratio and 6-month neurological outcome in patients with in-hospital cardiac arrest

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World Journal of Emergency Medicine 2024年第3期15卷 223-228页

作者： Ji Ho Lee dong Hun Lee Byung Kook Lee Seok jin Ryu Department of Emergency Medicine Chonnam National University HospitalGwangju 61469Republic of Korea Department of Emergency Medicine Chonnam National University Medical SchoolGwangju 61469Republic of Korea

The global incidence rates of in-hospital cardiac arrest(IHCA)range from1.2 to 9.0 per1,000 hospitalized patients,as per the National Cardiac Arrest Database.[1] While IHCAs tend to exhibit superior 30-day survival rates relative to out-of-hospital cardiac arrests (OHCA) due to situational advantages,such as immediate access to medical personnel and treatments.

关键词： patients cardiac IHC

Directional amine-based solvent extraction for simultaneous enhanced water recovery,salt separation and effective descaling from hypersaline brines

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Frontiers of Environmental Science & Engineering 2024年第3期18卷 83-92页

作者： Yuyao Zhang Litao Jia jin Zhao Xuming Liu Shuyu dong Chuanyang Liu Yuanyuan Cui Shougang Research Institute of Technology Beijing 100043China Research Center of Environmental Technology in Water Pollution Source Identification and Precise Supervision School of EnvironmentTsinghua UniversityBeijing 100084China

The feasibility of simultaneous water recovery,salt separation and effective descaling of hypersaline brine was investigated by diisopropylamine(DIPA)-based directional solvent extraction(DSE),using diluted/concentrated seawater with initial saline concentration range of 12–237 g/L at extraction temperatures of 5 and 15℃,*** water recovery shows an obvious boundary at saline concentration of 115 g/L under dual effect of specific water extraction efficiency and extraction *** Cl^(–) ion concentration in product water is in sharp contrast to the nearly complete removal of SO_(4)^(2–)and hardness ions,indicating that DIPA-based DSE process indeed achieved efficient separation and purification of Cl^(–) ion from hypersaline ***,the radical precipitation of Mg^(2+)and Ca^(2+)ions in form of Mg(OH)_(2)and CaCO_(3)demonstrates effective descaling potential,although it leads to more DIPA residues in dewatered raffinate than product ***,an exponential correlation between the Cl^(–) removal efficiency and specific water extraction efficiency further reveals the intrinsic relationship of water extraction process and transfer of Cl^(–) ion to the product ***,the study provides a novel approach for integrating the water recovery and separation of Cl^(–) ion from ultra-high-salinity brines with radical precipitation of Mg^(2+)and Ca^(2+) ions in one step.

关键词： Hypersaline brines Directional solvent extraction Salt separation Ca^(2+)and Mg^(2+)descaling

Investigation of the block toppling evolution of a layered model slope by centrifuge test and discrete element modeling

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第1期16卷 112-122页

作者： Leilei jin Hongkai dong Fei Ye Yufeng Wei Jianfeng Liu Changkui Wang State Key Laboratory of Hydraulic and Mountain River Engineering College of Water Resource and HydropowerSichuan UniversityChengdu610065China State Key Laboratory of Geohazard Prevention and Geoenvironment Protection Chengdu University of TechnologyChengdu610059China

Primary toppling usually occurs in layered rock slopes with large anti-dip *** this paper,the block toppling evolution was explored using a large-scale centrifuge *** block column in the layered model slope was made of cement *** artificial cracks perpendicular to the block column were *** gages,displacement gages,and high-speed camera measurements were employed to monitor the deformation and failure processes of the model *** centrifuge test results show that the block toppling evolution can be divided into seven stages,*** compression,formation of major tensile crack,reverse bending of the block column,closure of major tensile crack,strong bending of the block column,formation of failure zone,and complete *** toppling is characterized by sudden large deformation and occurs in *** wedge-shaped cracks in the model incline towards the *** observations show that block toppling is mainly caused by bending failure rather than by shear *** tensile strength also plays a key factor in the evolution of block *** simulation results from discrete element method(DEM)is in line with the testing *** stress exists at the backside of rock column during toppling *** concentration results in the fragmented rock column and its degree is the most significant at the slope toe.

关键词： Block toppling Centrifuge Anti-dip slope Failure mechanism Discrete element method

Two-Staged Method for Ice Channel Identification Based on Image Segmentation and Corner Point Regression

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China Ocean Engineering 2024年第2期38卷 313-325页

作者： dong Wen-bo ZHOU Li DING Shi-feng WANG Ai-ming CAI jin-yan School of Naval Architecture and Ocean Engineering Jiangsu University of Science and TechnologyZhenjiang 212003China School of Naval Architecture Ocean and Civil EngineeringShanghai Jiao Tong UniversityShanghai 200240China

Identification of the ice channel is the basic technology for developing intelligent ships in ice-covered waters,which is important to ensure the safety and economy of *** the Arctic,merchant ships with low ice class often navigate in channels opened up by *** in the ice channel often depends on good maneuverability skills and abundant experience from the captain to a large *** ship may get stuck if steered into ice fields off the *** this circumstance,it is very important to study how to identify the boundary lines of ice channels with a reliable *** this paper,a two-staged ice channel identification method is developed based on image segmentation and corner point *** first stage employs the image segmentation method to extract channel *** the second stage,an intelligent corner regression network is proposed to extract the channel boundary lines from the channel region.A non-intelligent angle-based filtering and clustering method is proposed and compared with corner point regression *** training and evaluation of the segmentation method and corner regression network are carried out on the synthetic and real ice channel *** evaluation results show that the accuracy of the method using the corner point regression network in the second stage is achieved as high as 73.33%on the synthetic ice channel dataset and 70.66%on the real ice channel dataset,and the processing speed can reach up to 14.58frames per second.

关键词： ice channel ship navigation identification image segmentation corner point regression

ZmMYC7转录因子调控玉米抗病相关功能的初步研究

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农业生物技术学报 2024年第1期32卷 1-10页

作者：王永桂李薇崔婷茹张福源杨文皓许荡非邢继红曹宏哲董金皋河北农业大学华北作物改良与调控国家重点实验室/河北省植物生理与分子病理学重点实验室保定市气象局张家口市林业工作总站

玉米(Zea mays)是全球最重要的粮食作物之一，病原菌引起的玉米病害直接影响玉米生产，导致巨大的经济损失。转录因子MYC2在植物抗病领域发挥重要作用。本实验室前期获得拟南芥(Arabidopsis thaliana) AtMYC2在玉米中的同源基因ZmMYC7(Z... 详细信息

玉米(Zea mays)是全球最重要的粮食作物之一，病原菌引起的玉米病害直接影响玉米生产，导致巨大的经济损失。转录因子MYC2在植物抗病领域发挥重要作用。本实验室前期获得拟南芥(Arabidopsis thaliana) AtMYC2在玉米中的同源基因ZmMYC7(Zm00001d030028)。为了探究转录因子ZmMYC7在调控玉米抗病过程中的功能，本研究检测ZmMYC7突变体对4种玉米真菌病害的敏感性，利用qRT-PCR技术检测ZmMYC7突变对病程相关蛋白(pathogenesis-related protein, PR)基因表达的影响。结果显示，ZmMYC7与高粱(Sorghum bicolor) SbMYC2的同源性最高(90%);ZmMYC7在玉米的叶和花药中表达水平较高，紫外照射和禾谷镰刀菌(Fusarium graminearum)侵染会上调ZmMYC7基因表达；ZmMYC7突变后，玉米对叶和茎部病害的敏感性显著增加，病程相关蛋白基因ZmPRs的表达显著下调(P<0.01)。上述结果提示ZmMYC7可能在玉米抗病过程中发挥作用。本研究为深入解析ZmMYC7调控玉米抗病的分子机制提供基础资料。

关键词： ZmMYC7 病程相关蛋白(PR) 病原体禾谷镰刀菌转录因子

Numerical design optimization of compressor blade based on ADOP

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航空动力学报 2007年第11期22卷 1903-1908页

作者： jin dong-hai GUI Xing-min School of Jet Propulsion Beijing University of Aeronautics and Astronautics Beijing 100083 China

An aerodynamic design optimization platform(ADOP) has been *** numerical optimization method is based on genetic algorithm(GA),Pareto ranking and fitness sharing *** platform was used for design optimization of the stator of an advanced transonic stage to seek high adiabatic *** compressor stage efficiency is increased by 0.502% at optimal point and the stall margin is enlarged by nearly 1.0% at design rotating *** flow fields of the transonic stage were simulated with FINE/Turbo software *** optimization result indicates that the optimization platform is effective in 3D numerical design optimization problems.

关键词：最优化设计压缩机桨片空气动力学 ADOP 遗传算法

玉米大斑病菌铁载体合成基因簇鉴定及表达分析

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农业生物技术学报 2024年第5期32卷 1121-1131页

作者：岳浩峰赵天益李海笑闫秋静徐雅迪孟亚南曹志艳刘宁董金皋河北农业大学生命科学学院华北作物改良与调控国家重点实验室/河北省植物生理与分子病理学重点实验室河北农业大学植物保护学院

铁是微生物生长必需的元素，在氧代谢、电子转移以及DNA和RNA合成等过程中发挥重要作用，微生物主要依赖于铁载体吸收环境中的铁离子。铁载体作为微生物分泌的低分子量铁螯合物，协助机体运输铁离子。真菌主要利用非核糖体多肽合成酶编... 详细信息

铁是微生物生长必需的元素，在氧代谢、电子转移以及DNA和RNA合成等过程中发挥重要作用，微生物主要依赖于铁载体吸收环境中的铁离子。铁载体作为微生物分泌的低分子量铁螯合物，协助机体运输铁离子。真菌主要利用非核糖体多肽合成酶编码基因为核心的次级代谢物生物合成基因簇合成铁载体，本研究旨在明确玉米大斑病菌(Setosphaeria turcica)铁载体的合成基因簇以及关键基因的表达。利用铬天青(chrome azurol sulphonate, CAS)鉴定玉米大斑病菌合成铁载体的类型并利用AntiSMASH网站预测其生物合成基因簇，利用玉米大斑病菌孢子不同发育时期的转录组数据及qRT-PCR分析病菌侵染过程中铁载体合成基因簇中各关键基因的表达水平以及外源铁浓度对基因表达的影响。结果表明，玉米大斑病菌产生异羟肟酸盐型铁载体，在基因组中鉴定得到1个产生异羟肟酸盐铁载体的次级代谢物生物合成基因簇，由非核糖体多肽合成酶(nonribosomal peptide synthetase, NRPS)编码基因StNPS6为核心的12个铁载体合成相关基因组成。在玉米大斑病菌孢子萌发和侵染玉米叶片的过程中，基因簇中多个基因表达显著上调。与菌丝时期相比，侵染6 d后StNPS6表达量上调5.52倍，侵染9 d时后辅助合成基因StrhbE表达量上调24.12倍，编码转运相关蛋白的基因Stpmd1上调19.95倍。同时发现富铁和贫铁均对病菌的生长具有一定的抑制作用，且富铁情况下病菌黑色素合成受阻，培养基中铁含量差异导致基因簇中多个基因表达量显著变化，尤其是转运相关蛋白基因Stpmd1在富铁条件下表达量上升73.28倍。本研究为解析玉米大斑病菌铁载体的潜在作用提供了参考。

关键词：玉米大斑病菌铁载体次级代谢产物生物合成基因簇基因表达

Experiment of heat transfer in oscillating turbulent flow in a pipe with constant heat flux

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航空动力学报 2013年第9期28卷 1949-1955页

作者： LI Ming-zhen dong jin-zhong School of Energy and Power Engineering Beijing University of Aeronautics and Astronautics

Heat transfer characteristics of oscillating turbulent air flow in a pipe heated with constant heat flux were experimentally *** experiments were performed over a range of 245.7 to 902 of the kinetic Reynolds number and 25 to 175 of the dimensionless oscillation *** effects of these two dimensionless parameters were *** results show that the cycle-averaged local Nusselt number increases with both the kinetic Reynolds number and the dimensionless oscillation *** space-cycle averaged Nusselt number also effectively increases with the kinetic Reynolds number and the dimensionless oscillation *** on the experimental data,a correlation equation of the space-cycle averaged Nusselt number for air in terms of these two dimensionless parameters has been obtained.

关键词： oscillating turbulent flow heat transfer kinetic Reynolds number Nusselt number constant heat flux

Natural products inspired[3+2]cycloaddition enables efficient construction of hydroxylated tetrahydrofuran acetals and concise syntheses of lignans

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Science China Chemistry 2024年第7期67卷 2306-2313页

作者： dong-Yue Cai Weiming Shi Zhao-Hui jin Zhi-Xiang Yu jin-Xin Zhao Jian-Min Yue State Key Laboratory of Drug Research Shanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China University of Chinese Academy of Sciences Beijing 100049China Beijing National Laboratory for Molecular Sciences(BNLMS) Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of EducationCollege of ChemistryPeking UniversityBeijing 100871China

Mimicking biosynthetic pathways of hongkonoids led to the development of a new Cu(Ⅰ)-catalyzed[3+2]cycloaddition ofα-hydroxyketone andβ-keto enol ethers,affording tetrahydrofuran acetals in a highly diastereoselective manner and 100%atom *** studies on the mechanism disclosed a concerted but asynchronous Michael addition/aldol *** the same importance,this methodology provides a practical biomimetic approach for one-step construction of the dibenzylbutyrolactol lignan backbone starting from two phenyl propane derivatives,opening up a powerful new approach for lignan synthesis,which is showcased by succinct total syntheses of two biologically important aryltetralin-type lignans,β-apopicropodophyllin and *** the mild and operationally simple conditions,the developed chemistry might have a promising prospect in potential industrial applications.

关键词： [3+2]cycloaddition transition-metal catalysis tetrahydrofuran lignans natural products

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