检索结果-南通市图书馆

在线全文

学校读者我要写书评

暂无评论

精囊在男性性功能中的作用

中华男科学杂志 2024年第3期30卷 195-198页

作者：金保方孙大林东南大学附属中大医院中西医结合男科江苏南京210009

精囊是男性生殖系统重要的附属性腺,过去有些学者多关注其在受精过程中的作用,而忽略了与男性性功能的关系。研究发现精囊参与性欲、勃起和射精等多个环节,针对精囊用药治疗性功能障碍,取得了一定的疗效。本文就生理病理以及临床和基础... 详细信息

精囊是男性生殖系统重要的附属性腺,过去有些学者多关注其在受精过程中的作用,而忽略了与男性性功能的关系。研究发现精囊参与性欲、勃起和射精等多个环节,针对精囊用药治疗性功能障碍,取得了一定的疗效。本文就生理病理以及临床和基础研究方面,论述精囊与性功能的关系,期望能为临床诊治性功能障碍提供新思路。

关键词：精囊性功能障碍性欲低下勃起功能障碍不射精

Insights into postural orthostatic tachycardia syndrome after COVID-19 in pediatric patients

在线全文

学校读者我要写书评

暂无评论

World Journal of Pediatrics 2024年第3期20卷 201-207页

作者： Ya-Xi Cui Jun-bao Du Hong-fang jin Department of Pediatrics Peking University First HospitalNo.1 Xi-an Men StreetWest DistrictBeijing 100034China State Key Laboratory of Vascular Homeostasis and Remodeling Peking UniversityBeijing 100191China

The pandemic caused by the novel severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)profoundly threatened human health globally and greatly impacted the world economy[1].While most patients recovered,some suff... 详细信息

关键词： acute patients tachycardia

Clinical observation of extraction-site incisional hernia after laparoscopic colorectal surgery

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Surgery 2024年第3期16卷 710-716页

作者： bao-Hang Fan Ke-Li Zhong Li-jin Zhu Zhao Chen fang Li Wen-Fei Wu Second Clinical Medical College of jinan University Jinan UniversityShenzhen 518020Guangdong ProvinceChina Department of Gastrointestinal Surgery Shenzhen People’s Hospital(The Second Clinical Medical CollegeJinan UniversityThe First Affiliated HospitalSouthern University of Science and Technology)Shenzhen 518020Guangdong ProvinceChina Department of Radiation Oncology Shenzhen People’s Hospital(The Second Clinical Medical CollegeJinan UniversityThe First Affiliated HospitalSouthern University of Science and Technology)Shenzhen 518020Guangdong ProvinceChina

BACKGROUND Laparoscopic colorectal cancer surgery increases the risk of incisional hernia(IH)at the tumor extraction site.AIM To investigate the incidence of IH at extraction sites following laparoscopic colo-rectal cancer surgery and identify the risk factors for IH incidence.METHODS This study retrospectively analyzed the data of 1614 patients who underwent la-paroscopic radical colorectal cancer surgery with tumor extraction through the abdominal wall at our center between January 2017 and December 2022.Diffe-rences in the incidence of postoperative IH at different extraction sites and the risk factors for IH incidence were investigated.RESULTS Among the 1614 patients who underwent laparoscopic radical colorectal cancer surgery,303(18.8%),923(57.2%),171(10.6%),and 217(13.4%)tumors were ex-tracted through supraumbilical midline,infraumbilical midline,umbilical,and off-midline incisions.Of these,52 patients developed IH in the abdominal wall,with an incidence of 3.2%.The incidence of postoperative IH was significantly higher in the off-midline incision group(8.8%)than in the middle incision groups[the supraumbilical midline(2.6%),infraumbilical midline(2.2%),and umbilical incision(2.9%)groups](χ^(2)=24.985;P<0.05).Univariate analysis showed that IH occurrence was associated with age,obesity,sex,chronic cough,incision infection,and combined diabetes,anemia,and hypopro-teinemia(P<0.05).Similarly,multivariate analysis showed that off-midline incision,age,sex(female),obesity,incision infection,combined chronic cough,and hypoproteinemia were independent risk factors for IH at the site of laparoscopic colorectal cancer surgery(P<0.05).CONCLUSION The incidence of postoperative IH differs between extraction sites for laparoscopic colorectal cancer surgery.The infraumbilical midline incision is associated with a lower hernia rate and is thus a suitable tumor extraction site.

关键词： Incisional hernia Laparoscopy Colorectal cancer Incision infection

Spin injection in a ferromagnet/resonant tunneling diode heterostructure

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of University of Science and Technology Beijing 2008年第5期15卷 638-643页

作者： jin bao fang Wan Yu Wang Xiaoguang Xu Yong Jiang School of Materials Science and Engineering University of Science and Technology Beijing Beijing 100083 China

The spin transport property of a ferromagnet （FM）/insulator （Ⅰ）/resonant tunneling diode （RTD） heterostructure was studied. The transmission coefficient and spin polarization in a multilayered heterostructure was calculated by a Schrdinger wave equation. An Airy function formalism approach was used to solve this equation. Based on the transfer matrix approach,the transmittivity of the structure was determined as a function of the Feimi energy and other parameters. The result shows that the spin polarization induced by the structure oscillates with the increasing Fermi energy of the FM layer. While the thickness of the RTD is reduced,the resonant peaks become broad. In the heterostructure,the spin polarization reaches as high as 40% and can be easily controlled by the external bias voltage.

关键词： spin injection resonant tunneling diode heterostructure spin polarization

Hydrogen sulfide and vascular relaxation

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2011年第22期124卷 3816-3819页

作者： SUN Yan TANG Chao-shu DU Jun-bao jin Hong-fang Department of Pediatrics Peking University First Hospital Beiiing 100034 China

Objective To review the vasorelaxant effects of hydrogen sulfide （H2S） in arterial rings in the cardiovascular system under both physiological and pathophysiological conditions and the possible mechanisms involved. Data sources The data in this review were obtained from Medline and Pubmed sources from 1997 to 2011 using the search terms ＂hydrogen sulfide＂ and ＂vascular relaxation＂. Study selection Articles describing the role of hydrogen sulfide in the regulation of vascular activity and its vasorelaxant effects were selected. Results H2S plays an important role in the regulation of cardiovascular tone. The vasomodulatory effects of H2S depend on factors including concentration, species and tissue type. The H2S donor, sodium hydrosulfide （NariS）, causes vasorelaxation of rat isolated aortic rings in a dose-dependent manner. This effect was more pronounced than that observed in pulmonary arterial rings. The expression of KATp channel proteins and mRNA in the aortic rings was increased compared with pulmonary artery rings. H2S is involved in the pathogenesis of a variety of cardiovascular diseases. Downregulation of the endogenous H2S pathway is an important factor in the pathogenesis of cardiovascular diseases. The vasorelaxant effects of H2S have been shown to be mediated by activation of KATP channels in vascular smooth muscle cells and via the induction of acidification due to activation of the Cr/HCO3 exchanger. It is speculated that the mechanisms underlying the vasoconstrictive function of H2S in the aortic rings involves decreased NO production and inhibition of cAMP accumulation. Conclusion H2S is an important endogenous gasotransmitter in the cardiovascular system and acts as a modulator of vascular tone in the homeostatic regulation of blood pressure.

关键词： hydrogen sulfide, vasorelaxing effects cardiovascular system

Activity regulation and applications of metal-organic framework-based nanozymes

在线全文

学校读者我要写书评

暂无评论

Rare Metals 2024年第3期43卷 900-914页

作者： Ge fang Shou-Xin bao Gen-Xiu Zhou Cui-Cui Ge State Key Laboratory of Radiation Medicine and Protection School of Radiation Medicine and ProtectionSchool for Radiological and Interdisciplinary Sciences(RAD-X)Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education InstitutionsSoochow UniversitySuzhou 215123China Suzhou Nanomicro Technology Co. LtdSuzhou 215000China

As a new generation of artificial enzymes,nanozymes show outstanding advantages such as high stability,low cost,and facile synthesis,which endow them with promising applications in biomedical and environmental fields.Among the various reported nanozymes,metal-organic frameworks(MOFs)could mimic the active center of natural enzymes and provide a hydrophobic environment,which makes MOFs attractive alternatives to natural enzymes.Owing to the highly structural diversity and tailorability of MOFs,rational design will contribute to improve the activity of MOF-based nanozymes and promote their potential applications in both biomedical and environmental fields.Therefore,a comprehensiye suminary of activity regulatory strategies of MOF-based nanozymes is urgently needed.Firstly,we summarized the activity regulatory strategies of MOFs with intrinsic enzyme-like activities via modulation of metal nodes,ligands,structures and morphologies.Then the applications of MOF-based nanozymes in biosensing,hazardous degradation,antibacterial,and cancer therapy were also introduced.Finally,the current challenges and future perspectives were discussed in depth.It is highly expected that this review will provide a better understanding on the rational design of novel high-performance MOF-based nanozymes.

关键词： Metal-organic frameworks(MOF)-based nanozymes Activity regulation Biosensing Cancer therapy Hazardous degradation Antibacterial

Fight or flee,a vital choice for Clostridioides difficile

在线全文

学校读者我要写书评

暂无评论

mLife 2024年第1期3卷 14-20页

作者： Ji Zeng Sshuying fang jinquan Guo Min Dong Guo-bao Tian Liang Tao School of Biomedical and Pharmaceutical Sciences Guangdong University of TechnologyGuangzhouChina Department of Brest Surgery Panyu Central Hospital.GuangzhouChina Department of Microbiology Harvard Medical SchoolBostonMassachusettsUSA Department of Urology Boston Children's HospitalHarvard Medical SchoolBostonMassachusettsUSA Department of Microbiology Zhongshan School of MedicineSun Yat-sen UniversityGuangzhouChina Advanced Medical Technology Center The First Affiliated HospitalZhongshan School of MedicineSun Yat-sen UniversityGuangzhouChina Key Laboratory of Tropical Diseases Control(Sun Yat-sen University) Ministry of EducationGuangzhouChina School of Medicine Xizang Minzu UniversityXianyangChina Center for Infectious Disease Research Westlake Laboratory of Life Sciences and BiomedicineWestlake UniversityHangzhouChina Research Center for Industries of the Future School of Life SciencesWestlake UniversityHangzhouChina

Clostridioides difficile is a leading cause of healthcare-associated infections,causing billions of economic losses every year.Its symptoms range from mild diarrhea to life-threatening damage to the colon.Transmission and recurrence of c.difficile infection(CDl)are mediated by the metabolically dormant spores,while the virulence of C.difficile is mainly due to the two large clostridial toxins,TcdA and TcdB.Producing toxins or forming spores are two different strategies for C.difficile to cope with harsh environmental conditions.It is of great significance to understand the molecular mechanisms for C.difficile to skew to either of the cellular processes.Here,we summarize the current understanding of the regulation and connections between toxin production and sporulation in C.difficile and further discuss the potential solutions for yet-to-be-answered questions.

关键词： C.difficile sporulation TcdA TcdB toxin production

Status, Reflection, and Outlook of Andrology of Integrative Medicine

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Status, Reflection, and Outlook of Andrology of Integrative ...

Adaptive pandemic management strategies for construction sites:An agent-based modeling approach

首届男性大健康中西医协同创新论坛暨第三届全国中西医结合...

作者： jin bao-fang LI Hong-jun SUN Da-lin YANG Wen-tao Andrology Department of Integrative Medicine Zhongda Hospital School of Medicine Southeast University Department of Urology Peking Union Medical College Hospital Peking Union Medical College Chinese Academy of Medical Sciences Department of Andrology Ruikang Hospital Affiliated to Gunagxi University of Chinese Medicine

Andrology of traditional Chinese medicine(TCM) and of western medicine belong to two parallel disciplines based on different social and humanistic backgrounds, which lay a solid foundation for andrology of integrative medicine.However, the difficulties and deficiencies in TCM and western medicine render incomplete theoretical system. Andrology of integrative medicine is still in its infancy. We need further elucidation of the advantages of integrative medicine.Subsequently, knowledge of male disease on large scale can be realized and the establishment of a characteristic modern andrology can be archived.

关键词： Integrative Medicine Andrology LOH male infertility chronic prostatitis kidney deficiency

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Frontiers of Engineering Management 2024年第2期11卷 288-310页

作者： Chengqian LI Qi fang Ke CHEN Zhikang bao Zehao JIANG Wenli LIU School of Civil Engineering Hunan UniversityChangsha 410082China School of Civil Engineering Central South UniversityChangsha 410004China School of Civil and Hydraulic Engineering Huazhong University of Science and TechnologyWuhan 430074China School of Energy GeoscienceInfrastructureand SocietyHeriot-Watt UniversityEdinburghUK

In the face of sudden pandemics,it becomes crucial for project managers to quickly adapt and make informed decisions that anticipate the consequences of their actions.This highlights the need for proactive management strategies to enhance epidemic response efforts.However,current research mainly emphasizes the negative impacts of pandemics,often neglecting the development of adaptable management approaches for construction sites.This study aims to fill this research void by developing strategies tailored to managing pandemics at construction sites.Using agent-based modeling,the study simulates the movement patterns of workers and the consequent spread of an epidemic under different risk scenarios and management tactics.The results indicate that measures such as wearing masks,managing group activities,and enforcing entry controls can significantly reduce epidemic spread on construction sites,with entry controls showing the greatest effectiveness.

关键词： epidemic transmission agent-based modeling safety management management strategy