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不同空间尺度下装备制造业协同创新及影响因素研究——以黑龙江省为例

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经济体制改革 2018年第4期 132-138页

作者：焦智博刘洪德郭喆哈尔滨工程大学经济管理学院

本文运用1985~2017年专利合作数据、统计数据及半结构访谈数据,分析不同空间尺度下装备制造业协同创新及其影响因素。研究表明:装备制造业协同创新网络具有邻近性和层级性特征,城市尺度、国家尺度是主要的创新空间,直辖市和省会城市的... 详细信息

本文运用1985~2017年专利合作数据、统计数据及半结构访谈数据,分析不同空间尺度下装备制造业协同创新及其影响因素。研究表明:装备制造业协同创新网络具有邻近性和层级性特征,城市尺度、国家尺度是主要的创新空间,直辖市和省会城市的创新主体在协同创新网络中占据着核心位置,创新主体属性、创新环境和合作对象对装备制造业协同创新水平有显著影响,优化创新要素和完善创新环境是提升黑龙江装备制造业协同创新水平的关键路径。

关键词：协同创新影响因素装备制造业黑龙江

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群体性事件的成因分析

边疆经济与文化 2010年第9期 54-55页

作者：焦智博刘大勇东北农业大学人文学院哈尔滨150030

中国正处于社会转型期。近些年来群体性事件日渐增多,并以其涉及面广、组织性强、社会影响力大等特点成为影响社会稳定的突出问题。应科学分析当前社会背景下群体性事件产生的深层次、多方面原因,妥善化解矛盾,以促进社会的稳定和谐。

关键词：群体性事件成因分析

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八五三地震台地壳结构与泊松比浅析

防灾减灾学报 2021年第3期37卷 48-52页

作者：李大伟教智浡胡宝慧鹤岗地震台黑龙江鹤岗154100

整理收集2017年1月—2018年9月八五三地震台记录到的远震地震事件,采用频率域反褶积方法提取P波径向接收函数,运用H-Kappa叠加方法反演台站下方地壳厚度及壳内物质泊松比。结果表明:八五三地震台下方的地壳厚度为34.6km,泊松比值较低,为... 详细信息

整理收集2017年1月—2018年9月八五三地震台记录到的远震地震事件,采用频率域反褶积方法提取P波径向接收函数,运用H-Kappa叠加方法反演台站下方地壳厚度及壳内物质泊松比。结果表明:八五三地震台下方的地壳厚度为34.6km,泊松比值较低,为0.226;反映了台站下方地壳物质岩性二氧化硅含量较高,熔融度低的长英质岩;推断为上地壳的沉降作用引起的地壳增厚。结合前人研究成果,认为三江盆地周缘地壳厚度为“东西边厚,南边薄”的特点。

关键词：八五三地震台接收函数地壳厚度泊松比

The autophagy-lysosome pathway:a potential target in the chemical and gene therapeutic strategies for Parkinson’s disease

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Neural Regeneration Research 2025年第1期20卷 139-158页

作者： Fengjuan jiao Lingyan Meng Kang Du Xuezhi Li School of Mental Health Jining Medical UniversityJiningShandong ProvinceChina Shandong Collaborative Innovation Center for Diagnosis Treatment and Behavioral Interventions of Mental DisordersInstitute of Mental HealthJining Medical UniversityJiningShandong ProvinceChina

Parkinson’s disease is a common neurodegenerative disease with movement disorders associated with the intracytoplasmic deposition of aggregate proteins such asα-synuclein in *** one of the major intracellular degradation pathways,the autophagy-lysosome pathway plays an important role in eliminating these *** evidence has shown that upregulation of the autophagy-lysosome pathway may contribute to the clearance ofα-synuclein aggregates and protect against degeneration of dopaminergic neurons in Parkinson’s ***,multiple genes associated with the pathogenesis of Parkinson’s disease are intimately linked to alterations in the autophagy-lysosome ***,this pathway appears to be a promising therapeutic target for treatment of Parkinson’s *** this review,we briefly introduce the machinery of ***,we provide a description of the effects of Parkinson’s disease–related genes on the autophagy-lysosome ***,we highlight the potential chemical and genetic therapeutic strategies targeting the autophagy–lysosome pathway and their applications in Parkinson’s disease.

关键词： autophagy chemical therapy gene therapy Parkinson’s disease α-synuclein

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鹤岗地震台台基背景噪声特征分析

防灾减灾学报 2020年第4期36卷 51-56页

作者：姜博胡宝慧常金龙张浩教智浡鹤岗地震台黑龙江鹤岗154101

本文选取了鹤岗地震台2008、2009年及2018、2019年相同时间段内的数字观测资料数据,对观测数据的地动噪声功率谱密度、地动噪声RMS值、观测动态范围等参数进行计算分析,通过数据对比分析,得到了鹤岗台区域的近十年背景噪声的变化特征。... 详细信息

本文选取了鹤岗地震台2008、2009年及2018、2019年相同时间段内的数字观测资料数据,对观测数据的地动噪声功率谱密度、地动噪声RMS值、观测动态范围等参数进行计算分析,通过数据对比分析,得到了鹤岗台区域的近十年背景噪声的变化特征。经过计算分析发现,2008、2009年分别对比2018、2019年的三分向噪声功率谱密度曲线一致性较差,RMS值变化较大,虽然功率谱密度PSD曲线介于NLNM和NHNM之间,但是整体观测动态范围有所下降,台站观测背景噪声增大、仪器自身老化等问题需要及时进行处理,分析结果可以作为台站的背景噪声参考数据,为以后研究台站背景噪声积累可靠的数据资料。

关键词：地震数据功率谱密度观测动态范围干扰分析

Advances in the Development of Gradient Scaffolds Made of Nano-Micromaterials for Musculoskeletal Tissue Regeneration

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NANO-MICRO LETTERS 2025年第1期17卷 1-46页

作者： Fang, Lei Lin, Xiaoqi Xu, Ruian Liu, Lu Zhang, Yu Tian, Feng Li, jiao jiao Xue, Jiajia Beijing Univ Chem Technol Beijing Lab Biomed Mat Beijing 100029 Peoples R China Beijing Univ Chem Technol State Key Lab Organ Inorgan Composites Beijing 100029 Peoples R China Univ Technol Sydney Fac Engn & IT Sch Biomed Engn Sydney NSW 2007 Australia

This review highlights the gradient variations in the structural composition of musculoskeletal tissues and comprehensively examines recent progress in the fabrication and application of biomimetic gradient scaffolds for musculoskeletal *** challenges and prospects of gradient scaffolds for clinical application are discussed. The intricate hierarchical structure of musculoskeletal tissues, including bone and interface tissues, necessitates the use of complex scaffold designs and material structures to serve as tissue-engineered substitutes. This has led to growing interest in the development of gradient bone scaffolds with hierarchical structures mimicking the extracellular matrix of native tissues to achieve improved therapeutic outcomes. Building on the anatomical characteristics of bone and interfacial tissues, this review provides a summary of current strategies used to design and fabricate biomimetic gradient scaffolds for repairing musculoskeletal tissues, specifically focusing on methods used to construct compositional and structural gradients within the scaffolds. The latest applications of gradient scaffolds for the regeneration of bone, osteochondral, and tendon-to-bone interfaces are presented. Furthermore, the current progress of testing gradient scaffolds in physiologically relevant animal models of skeletal repair is discussed, as well as the challenges and prospects of moving these scaffolds into clinical application for treating musculoskeletal injuries.

关键词： Gradient scaffolds Musculoskeletal tissues Advanced manufacturing Biomaterials Tissue regeneration

High-energy-density lithium manganese iron phosphate for lithium-ion batteries: Progresses, challenges, and prospects

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Journal of Energy Chemistry 2025年第1期100卷 1-17页

作者： bokun Zhang Xiaoyun Wang Shuai Wang Yan Li Libo Chen Handong jiao zhijing Yu Jiguo Tu State Key Laboratory of Advanced Metallurgy University of Science and Technology Beijing Research Institute for Intelligent Wearable Systems The Hong Kong Polytechnic University Institute of Advanced Structure Technology Beijing Institute of Technology

The soaring demand for smart portable electronics and electric vehicles is propelling the advancements in high-energy–density lithium-ion *** manganese iron phosphate (LiMnxFe1-xPO4) has garnered significant attention as a promising positive electrode material for lithium-ion batteries due to its advantages of low cost,high safety,long cycle life,high voltage,good high-temperature performance,and high energy *** LiMnxFe1-xPO4has made significant breakthroughs in the past few decades,there are still facing great challenges in poor electronic conductivity and Li-ion diffusion,manganese dissolution affecting battery cycling performance,as well as low tap *** review systematically summarizes the reaction mechanisms,various synthesis methods,and electrochemical properties of LiMnxFe1-xPO4to analyze reaction processes accurately and guide material ***,the main challenges currently faced are concluded,and the corresponding various modification strategies are discussed to enhance the reaction kinetics and electrochemical performance of LiMnxFe1-xPO4,including multi-scale particle regulation,heteroatom doping,surface coating,as well as microscopic morphology ***,in view of the current research challenges faced by intrinsic reaction processes,kinetics,and energy storage applications,the promising research directions are *** importantly,it is expected to provide key insights into the development of high-performance and stable LiMnxFe1-xPO4materials,to achieve practical energy storage requirements.

关键词： Lithium manganese iron phosphate High energy density Lithium-ion batteries Reaction mechanism Tap density

地震台站噪声水平和台网监测能力自动化程序的实现

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防灾减灾学报 2022年第3期38卷 42-47页

作者：胡宝慧张浩教智博雷凯悦黑龙江省地震局黑龙江哈尔滨150090

在Linux环境下,应用Perl、MATLAB脚本程序实现地震台站噪声水平和台网理论监测能力的自动计算和绘图。基于该套程序,可以从JOPENS记录下的台网小时波形文件实现任意单台噪声水平的快速计算和台网监测能力的快速估计。该自动处理程序自... 详细信息

在Linux环境下,应用Perl、MATLAB脚本程序实现地震台站噪声水平和台网理论监测能力的自动计算和绘图。基于该套程序,可以从JOPENS记录下的台网小时波形文件实现任意单台噪声水平的快速计算和台网监测能力的快速估计。该自动处理程序自使用以来,运行良好,对台网内仪器监测效能的提升起到了积极作用。

关键词：噪声水平监测能力计算方法自动化

SensFL:Privacy-Preserving Vertical Federated Learning with Sensitive Regularization

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Computer Modeling in Engineering & Sciences 2025年第1期142卷 385-404页

作者： Chongzhen Zhang zhichen Liu Xiangrui Xu Fuqiang Hu jiao Dai Baigen Cai Wei Wang School of Automation and Intelligence Beijing Jiaotong UniversityBeijing100044China Shuohuang Railway Development Co. Ltd.National Energy GroupCangzhou062350China Beijing Key Laboratory of Security and Privacy in Intelligent Transportation School of Computer Science and TechnologyBeijing Jiaotong UniversityBeijing100044China

In the realm of Intelligent Railway Transportation Systems,effective multi-party collaboration is crucial due to concerns over privacy and data *** Federated Learning(VFL)has emerged as a promising approach to facilitate such collaboration,allowing diverse entities to collectively enhance machine learning models without the need to share sensitive training ***,existing works have highlighted VFL’s susceptibility to privacy inference attacks,where an honest but curious server could potentially reconstruct a client’s raw data from embeddings uploaded by the *** vulnerability poses a significant threat to VFL-based intelligent railway transportation *** this paper,we introduce SensFL,a novel privacy-enhancing method to against privacy inference attacks in ***,SensFL integrates regularization of the sensitivity of embeddings to the original data into the model training process,effectively limiting the information contained in shared *** reducing the sensitivity of embeddings to the original data,SensFL can effectively resist reverse privacy attacks and prevent the reconstruction of the original data from the *** experiments were conducted on four distinct datasets and three different models to demonstrate the efficacy of *** results show that SensFL can effectively mitigate privacy inference attacks while maintaining the accuracy of the primary learning *** results underscore SensFL’s potential to advance privacy protection technologies within VFL-based intelligent railway systems,addressing critical security concerns in collaborative learning environments.

关键词： Vertical federated learning privacy defenses