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Shining in the dark:the big world of small peptides in plants

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aBIOTECH 2023年第3期4卷 238-256页

作者： Yan-Zhao feng Qing-feng Zhu jiao Xue Pei Chen Yang yu Guangdong Key Laboratory of Crop Germplasm Resources Preservation and Utilization Key Laboratory of South China Modern Biological Seed IndustryMinistry of Agriculture and Rural AffairsAgro-Biological Gene Research CenterGuangdong Academy of Agricultural SciencesGuangzhou 510640China

Small peptides represent a subset of dark matter in plant *** differential expression patterns and modes of action,small peptides act as important regulators of plant growth and devel*** the past 20 years,many small peptides have been identified due to technical advances in genome sequencing,bioinformatics,and chemical *** this article,we summarize the classifi-cation of plant small peptides and experimental strategies used to identify them as well as their potential use in agronomic *** review the biological functions and molecular mechanisms of small peptides in plants,discuss current problems in small peptide research and highlight future research directions in this *** review provides crucial insight into small peptides in plants and will contribute to a better understanding of their potential roles in biotechnology and agriculture.

关键词： Small peptide Biological function Regulatory mechanism Crop improvement

Microstructure and Properties of 3.5 vol.%TiBw/Ti6A14V Composite Tubes Fabricated by Hot-hydrostatic Extrusion

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Journal of Materials Science & Technology 2014年第7期30卷 710-714页

作者： Wencong Zhang Xueyan jiao Yang yu Jianlei Yang Yangju feng School of Materials Science and Engineering Harbin Institute of Technology at Weihai

Tubes of 3.5 vol,% TiB whiskers reinforced Ti6Al4V matrix composites （TiBw/Ti6Al4V） were successfully fabricated by a two-step hot-hydrostatic extrusion process：（3 extrusion at 1100 ℃ and subsequent near-β extrusion at 950℃. The dimensions of tubes were about 7 mm in diameter and 2 mm in thickness. A refined basket-weave structure in Ti6Al4V matrix was achieved at ambient temperature after the extrusion process. Besides, the original network structure formed by TiB whiskers synthesized was broken, while the TiB whiskers were preferentially aligned in the extruding direction. Meanwhile, a fibrous texture was evolved finally, resulting from partial dynamic recrystallization during the β extrusion and the involvement of α phase during the near-β extrusion. The tensile and compressive tests results showed that both the strength and ductility of the tubes were significantly improved. In particular, the tubes exhibited good mechanical properties at elevated temperatures.

关键词： Titanium matrix composites (TMCs) T/B whiskers Hot-hydrostatic extrusion Tube Microstructure Mechanical properties

Temperature and thermodynamic deformation analysis of the rotors on a twin screw multiphase pump with high gas volume fractions

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2011年第9期12卷 720-730页

作者： Tie-yu GAO Dong-fang YANG feng CAO Jin-cheng jiao School of Energy and Power Engineering Xi'an Jiaotong University Xi'an 710049 China

The pressure increasing process within a twin screw multiphase pump, under the condition of high gas volume fractions (GVFs), induces large temperature and pressure changes that cause the rotors to deform. Rotor deformations heavily influence the backflow of the multiphase fluid through clearances within the twin screw multiphase pump and these deformations may even lead to pump failures. An accurate temperature and pressure distribution on the screw rotors need be obtained before the deformation analysis can be carried out. By means of small temperature and pressure sensors embedded into the groove at the root of the rotors, the temperatures of 12 points on the rotors and the pressure distributions of a twin screw multiphase pump under high GVFs conditions were recorded. Temperature test results were adopted to perform a heat transfer analysis for determining the temperature distribution on the screw rotors. Then deformation analyses, including thermal deformation, force deformation, and total deformation, were conducted according to the pressure and temperature distributions. Deformation analysis for different materials was also conducted under the same boundary conditions. A material was suggested for the manufacturing of rotors in a twin screw multiphase pump under the condition of high gas volume fractions.

关键词： Multiphase pump Twin screw rotor Thermal deformation Finite element analysis

Type Ⅰ neurofibromatosis with spindle cell sarcoma: A case report

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World Journal of Clinical Cases 2019年第19期7卷 3104-3110页

作者： yu Zhang jiao-jiao Chao Xiu-feng Liu Shu-Kui Qin BaYi Hospital Affiliated to Nanjing University of Chinese Medicine Nanjing University of Chinese MedicineNanjing 210000Jiangsu ProvinceChina Department of Oncology BaYi Hospital Affiliated to Nanjing University of Chinese MedicineNanjing 210000Jiangsu ProvinceChina

BACKGROUND Neurofibromatosis type Ⅰ(NF1) is the most frequent subtype of neurofibromatosis. Its related tumor-suppressor syndromes are characterized by a predisposition to multiple tumor types and other disorder presentations. In addition, the incidence of tumors is much higher in patients with neurofibromatosis type Ⅰ. However, there are very few reports at home and abroad on this topic. Here, we present a case of NF1 with spindle cell *** SUMMARY A 50-year-old male was found to have a right axillary mass for 20 *** examination found cafe-au-lait spots on many parts of the skin,rounded nodules in the skin, a bulge in the right armpit, touching a lump(10 cm× 6 cm, hard, unclear boundary, poor mobility, local tenderness). The anterior side of the thigh felt weakened on the opposite side;in the right groin a swollen lymph node(hard, clear border, good mobility, local tenderness). According to the results of positron emission tomography/computed tomography, puncture pathology and immunohistochemistry, genetic testing, a diagnosis of NF1 with spindle cell sarcoma was confirmed. According to the genetic testing result, the patient was given a targeted treatment with *** Surgery, chemotherapy and radiotherapy are the main treatment methods of NF1. However, with the continuous progress of molecular biology research,molecular targeted therapy may bring benefits for patients.

关键词： Neurofibromatosis Type Ⅰ Spindle cell sarcoma Targeted therapy Crizotinib Case report

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荷载与结构设计原理课程的教学改革探讨

教育教学论坛 2019年第28期 95-96页

作者：白晓红郭二伟赵果焦燏烽陈茜河南科技大学土木工程学院

荷载与结构设计原理课程是土木工程专业基础课,由于课程特点给实际教、学的过程都带来了困难。笔者在自身教学实践的基础上提出了提高教学质量的几项具体措施,通过对教学内容、教学方法、教学手段的调整、优化,并将改革措施落实到教材... 详细信息

荷载与结构设计原理课程是土木工程专业基础课,由于课程特点给实际教、学的过程都带来了困难。笔者在自身教学实践的基础上提出了提高教学质量的几项具体措施,通过对教学内容、教学方法、教学手段的调整、优化,并将改革措施落实到教材建设中,可有效提高教学效果,激发学生的积极性和创造性。

关键词：荷载与结构设计原理课程特点教学改革教材建设

Efficient Pd-Catalyzed C-H Oxidative Bromination of Arenes with Dimethyl Sulfoxide and Hydrobromic Acid

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Chinese Journal of Chemistry 2020年第11期38卷 1245-1251页

作者： Yizhi yuan yujie Liang Shihui Shi yu-feng Liang Ning jiao State Key Laboratory of Natural and Biomimetic Drugs School of Pharmaceutical SciencesPeking UniversityXue Yuan Rd.38Beijing 100191China State Key Laboratory of Organometallic Chemistry Shanghai Institute of Organic ChemistryChinese Academy of SciencesShanghai 200062China

of main observation and conclusion We have developed an efficient Pd-catalyzed directed C-H bromination protocol,in which dimethyl sulfoxide(DMSO)is employed as oxidant with hydrobromic add aqueous solution(HBr(aq))as bromide *** DMSO/HBr(aq)system,which is novelly and efficiently utilized in transition-metal catalyzed C-H activation,illustrates its practicability by the operational simplicity,inexpensive and readily available starting materials,and high bromide-atom economy.

关键词： catalyzed bromide simplicity

纯镁复合硅烷/植酸载锌膜层的细胞相容性实验研究

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口腔颌面外科杂志 2018年第1期28卷 14-20页

作者：明堃李德超李慕勤王心彧张慧明焦玉凤佳木斯大学口腔医学院黑龙江佳木斯154007 佳木斯大学黑龙江省高校生物医学材料重点实验室黑龙江佳木斯154007 佳木斯大学基础医学院生命科学实验中心黑龙江佳木斯154007

目的:制备纯镁复合硅烷/植酸载锌膜层,希望可以改善纯镁的耐腐蚀性及其细胞生物相容性。方法:制备纯镁阳极氧化、阳极氧化-硅烷处理、阳极氧化-硅烷/植酸双复合处理及硅烷/植酸双复合载Zn试样,采用扫描电镜观察涂层表面形貌,并进行分析... 详细信息

目的:制备纯镁复合硅烷/植酸载锌膜层,希望可以改善纯镁的耐腐蚀性及其细胞生物相容性。方法:制备纯镁阳极氧化、阳极氧化-硅烷处理、阳极氧化-硅烷/植酸双复合处理及硅烷/植酸双复合载Zn试样,采用扫描电镜观察涂层表面形貌,并进行分析元素,通过CCK-8检测细胞增殖和黏附能力,激光共聚焦检测细胞黏附形态。结果:纯镁阳极氧化表面存在微孔,复合处理起到封孔的作用,载不同浓度锌增加了细胞增殖和黏附能力,其中阳极氧化-硅烷/植酸双复合载Zn 20 g/L可防止细胞液浸入,生物相容性最佳。结论:纯镁阳极氧化-硅烷/植酸双复合载Zn 20 g/L膜层,细胞增长和形态铺展最好,明显促进了成骨细胞在材料表面的增殖、黏附能力及其生物功能表达。

关键词：纯镁阳极氧化硅烷/植酸锌含量细胞相容性

负载黄芪多糖的Span-PEG微泡的抑菌和超声造影效果

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精细化工中间体 2019年第4期49卷 31-34页

作者：宋立梅张杰张慧明王欣焦玉凤佳木斯大学

利用声振空化法制备负载黄芪多糖的Span-PEG微泡,考察其抑菌以及超声成像效果.实验结果表明,所制备的Span-PEG复合微泡平均粒径为595.3 nm、Zeta电位为-18.8 mV,Span-PEG复合微泡中黄芪多糖负载率为(8.60±0.24)%.Span-PEG复合微泡对大... 详细信息

利用声振空化法制备负载黄芪多糖的Span-PEG微泡,考察其抑菌以及超声成像效果.实验结果表明,所制备的Span-PEG复合微泡平均粒径为595.3 nm、Zeta电位为-18.8 mV,Span-PEG复合微泡中黄芪多糖负载率为(8.60±0.24)%.Span-PEG复合微泡对大肠杆菌和金黄色葡萄球菌具有抑菌作用,且效果随Span-PEG复合微泡浓度的增加而增强.Span-PEG复合微泡在家兔体内心脏、肾脏和子宫均具有显著的超声显影效果.

关键词：黄芪多糖超声造影剂抑菌超声成像

应急一体化管理、区域竞争力与城市韧性提升路径研究

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灾害学 2025年第1期40卷 146-152页

作者：窦路遥魏凤邓阿妹辛竹琳冯宇中国科学院武汉文献情报中心湖北武汉430071 中国科学院大学经济与管理学院信息资源管理系北京100190 科技大数据湖北省重点实验室湖北武汉430071 重庆大学经济与工商管理学院重庆400044

城市韧性建设关键在应急一体化管理和区域竞争力。有助于城市群高质量发展和减少灾害损失。该文基于组态思维整合应急一体化管理和区域竞争力9个相关要素,探讨影响城市韧性提升的多重并发因素和复杂因果机制。研究发现:①应急一体化管... 详细信息

城市韧性建设关键在应急一体化管理和区域竞争力。有助于城市群高质量发展和减少灾害损失。该文基于组态思维整合应急一体化管理和区域竞争力9个相关要素,探讨影响城市韧性提升的多重并发因素和复杂因果机制。研究发现:①应急一体化管理从成本可控性、资源协同性和政策支持性上影响城市韧性的提升,形成突发事件的事前预防、事中调配和事后恢复的逻辑闭环;而区域竞争力也分别从经济、发展、交易、生活层面上实现对城市韧性的综合描述。②高城市韧性组态分为强竞争力预防型、损失应激预防型、营商优化建设型、宜居持续建设型、政策支持拔高型,低城市韧性组态分为管理效能欠缺型和应急损失过度型。③在受损可控的范围内,灾害损失的出现反而可能在应急实践中促进韧性提升;过高的管理型支出会出现管理无效率的可能,而过低的管理型支出会出现管理失调的可能,都会产生抑制城市韧性的效果。

关键词：应急一体化管理区域竞争力城市韧性 fsQCA