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Comparison of the hygrothermal performance of two light-framed timber structure buildings under different operation modes

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2024年第1期25卷 18-35页

作者： Wanqing XU Yucong XUE jiang lu Yifan FAN Xiaoyu luO College of Civil Engineering and Architecture Zhejiang UniversityHangzhou310058China International Research Center for Green Building and Low-Carbon City International CampusZhejiang UniversityJiaxing314400China School of Civil Engineering and Architecture Zhejiang University of Science and TechnologyHangzhou310023China

Light-framed timber structure(LTS)buildings have been highly valued in recent years due to their low-carbon ***,the applicability of the building envelope is closely related to indoor and outdoor *** hot summer and cold winter(HSCW)climate zone in China has high humidity and great temperature variation throughout the year,resulting in distinct outdoor environments in different *** indoor environment is greatly affected by energy-consumption patterns and window-opening habits,which largely depend upon the regulation operations of *** these interrelated factors lead to extremely complex boundary conditions on each side of the building *** the structures of LTS buildings are applicable in this climate zone,therefore,needs to be carefully *** this study,two LTS buildings with different envelopes were established in Haining,China,situated in the HSCW climate zone,and selected as the study *** operation modes were adopted to create a variety of indoor *** each condition,the processes of heat and moisture transfer within the building envelopes and the indoor environment were monitored and *** comparison indicated that the building envelope with high moisture storage and insulation ability maintained a relatively stable indoor environment,especially when the environment changed ***,if the outdoor environment was equable(e.g.,relative humidity within the range of 30%–60%)or intermittent energy consumption modes were adopted,the building envelope with a low thermal inertia index and weak moisture-buffering ability performed better because it enabled a faster response of the indoor environment to air ***,a high risk of moisture accumulation between the thermal insulation layer and other materials with a large water vapour transfer resistance factor was also identified,suggesting a higher requirement for the vapour insulation of the env

关键词： Light-framed timber structure(LTS)buildings In-situ experiment Typical operation mode Indoor environment Heatand moisture transfer

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Emerging role of regulated cell death in intestinal failure-associated liver disease

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Hepatobiliary & Pancreatic Diseases International 2024年第3期23卷 228-233页

作者： Si-Yang Cheng lu jiang Ying Wang Wei Cai Department of Pediatric Surgery Xinhua HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200092China Shanghai Key Laboratory of Pediatric Gastroenterology and Nutrition Shanghai 200092China Shanghai Institute for Pediatric Research Shanghai 200092China Division of Pediatric Gastroenterology and Nutrition Xinhua HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200092China

Intestinal failure-associated liver disease(IFALD)is a common complication of long-term parenteral nutrition that is associated with significant morbidity and *** is mainly characterized by cholestasis in children and steatohepatitis in ***,there is no effective approach to prevent or reverse the *** cell death(RCD)represents a fundamental biological paradigm that determines the outcome of a variety of liver *** cell death is reclassified into several types,based on the mechanisms and morphological *** evidence has linked different modes of RCD,such as apoptosis,necroptosis,ferroptosis,and pyroptosis to the pathogenesis of liver *** studies have shown that different modes of RCD are present in animal models and patients with *** the pathogenic roles of cell death may help uncover the underlying mechanisms and develop novel therapeutic strategies in *** this review,we discuss the current knowledge on how RCD may link to the pathogenesis of *** highlight examples of cell death-targeted interventions aiming to attenuate the disease,and provide perspectives for future basic and translational research in the field.

关键词： Parenteral nutrition Apoptosis Necroptosis Cholestasis Steatosis

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Emerging Chemicals in China:Historical Development,Current Situation,and Future Outlook

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Environment & Health 2024年第4期2卷 180-188页

作者： Yawei Wang lu jiang Guibin jiang State Key Laboratory of Environmental Chemistry and Ecotoxicology Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China University of Chinese Academy of Sciences Beijing 100049China Hubei Key Laboratory of Environmental and Health Effects of Persistent Toxic Substances School of Environment and HealthJianghan UniversityWuhan 430056China

There has been a widespread international consensus to enhance the regulation of emerging chemicals in the 21st *** substantial implementation work conducted over the past two decades has established a strong foundation for the control of emerging chemicals across the ***,distinct challenges confront countries and regions due to the ever-evolving diverse national ***,as a developing nation and a major consumer of chemicals,is encountering particularly severe *** Perspective presents an overview encompassing the historical progression,current circumstances,and challenges confronted by China with regard to emerging *** central goal of these efforts is to prioritize the control of emerging chemicals and actively establish a monitoring ***,it is necessary to develop a multistakeholder environmental risk prevention and control ***,comprehensive efforts to enhance green substitution practices and active engagement of governance initiatives will be required.

关键词： Emerging chemicals New pollutants Problems and challenges Control suggestions Chinese solution

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The Effect and Mechanism of Fructus lycii on Improvement of Exercise Fatigue Using a Network Pharmacological Approach with in vitro Experimental Verification

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Biomedical and Environmental Sciences 2024年第1期37卷 42-53页

作者： JI Xiao Ning LIU Zhao Ping ZHANG Chao Zheng CHEN Min LIANG jiang lu jiang ZHANG Lei National Resource Center for Chinese Materia Medica China Academy of Chinese Medical SciencesBeijing 100700China China National Center for Food Safety Risk Assessment Beijing 100022China Chinese Center for Disease Control and Prevention Beijing 102206China

Objective This study aimed to investigate the effect and underlying mechanism of Fructus lycii in improving exercise *** A network pharmacological approach was used to explore potential mechanisms of action of Fructus *** muscle C2C12 cells and immunofluorescence were employed to verify the effect and mechanism of the representative components in Fructus lycii predicted by network pharmacological *** Six potential active components,namely quercetin,β-sitosterol,stigmasterol,7-Omethylluteolin-6-C-beta-glucoside_qt,atropine,and glycitein,were identified to have potency in improving exercise fatigue via multiple pathways,such as the PI3K-Akt,neuroactive ligand-receptor interaction,IL-17,TNF,and MAPK signaling *** immunofluorescence results indicated that quercetin,a significant active component in Fructus lycii,increased the mean staining area of 2-NBDG,TMRM,and MitoTracker,and decreased the area of CellRox compared to the ***,the protein expression levels of p-38 MAPK,p-MAPK,p-JNK,p-PI3K,and p-AKT markedly increased after quercetin *** Fructus lycii might alleviate exercise fatigue through multiple components and *** these,quercetin appears to improve exercise fatigue by enhancing energy metabolism and reducing oxidative *** PI3K-AKT and MAPK signaling pathways also appear to play a role in this process.

关键词： Fructus lycii Exercise fatigue Network pharmacology

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Gut microbiota in gastrointestinal diseases:Insights and therapeutic strategies

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World Journal of Gastroenterology 2024年第39期30卷 4329-4332页

作者： lu jiang Jian-Gao Fan Department of Pediatric Gastroenterology and Nutrition Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai 200092China Department of Gastroenterology Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai 200092China

Considering the bidirectional crosstalk along the gut-liver axis,gut-derived microorganisms and metabolites can be released into the liver,potentially leading to liver *** this editorial,we comment on several studies published in the recent issue of the World Journal of *** focus specifically on the roles of gut microbiota in selected gastrointestinal(GI)diseases that are prevalent,such as inflammatory bowel disease,metabolic dysfunction-associated steatotic liver disease,and hepatitis B virus-related portal *** the past few decades,findings from both preclinical and clinical studies have indicated an association between compositional and metabolic changes in the gut microbiota and the pathogenesis of the aforementioned GI ***,studies elucidating the mechanisms underlying the host-microbiota interactions remain *** purpose of this editorial is to summarize current findings and provide insights regarding the context-specific roles of gut ***,the discovery of microbiome-based biomarkers may facilitate disease diagnosis and the development of personalized medicine.

关键词： Gut microbiota Inflammatory bowel disease Metabolic dysfunction-associated steatotic liver disease Hepatitis B virus Portal hypertension

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Factors contributing to the oxygen concentration over the Qinghai-Tibetan Plateau and its contribution rate calculation

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Science China Earth Sciences 2024年第2期67卷 497-509页

作者： Peijun SHI Ying ZHANG Yanqiang CHEN Wenquan ZHU Xiaokang HU Heyi YANG lu jiang Yonggui MA Haiping TANG State Key Laboratory of Earth Surface Processes and Resource Ecology Beijing Normal UniversityBeijing100875China Key Laboratory of Environmental Change and Natural Disaster Ministry of EducationBeijing Normal UniversityBeijing100875China The Institute for Disaster Management and Reconstruction Sichuan UniversityChengdu610065China Academy of Plateau Science and Sustainability People’s Government of Qinghai Province&Beijing Normal UniversityXining810016China

A decline in atmospheric oxygen concentration is projected in the 21st century given the background of global *** Qinghai-Tibetan Plateau is located at a high altitude,and thus,it faces a hypoxia challenge;however,knowledge of the factors contributing to its atmospheric oxygen concentration is still ***,we conducted joint observations of ecosystem oxygen production and carbon sinks and near-surface atmospheric oxygen concentrations on the Qinghai-Tibetan Plateau and meteorological elements at Beijing Fangshan *** seasonal differences and statistical methods,we calculated the relative contribution rates of vegetation to changes in atmospheric oxygen *** results indicate that solar radiation,atmospheric humidity,and ecosystem oxygen consumption and production have a significant impact on the atmospheric oxygen concentration,and the impact shows temporal and spatial *** significantly impacts the oxygen concentration,with a contribution rate of 16.7%–24.5%,which is underestimated in existing *** findings provide important insights into the factors that influence atmospheric oxygen concentration and highlight the contribution of *** better understand the oxygen dynamics of the Qinghai-Tibetan Plateau,we recommend further field observations of soil respiration and vegetation photosynthesis to clarify the contributions of carbon storage,carbon sinks and other factors to the near-surface atmospheric oxygen concentration.

关键词： Qinghai-Tibetan Plateau Oxygen concentration Relative contribution rate Air temperature Vegetation

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A Multimodal Critical Discourse Analysis of Lingnan Cultural Promotional Videos on Social Media

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Journal of Contemporary Educational Research 2024年第4期8卷 59-68页

作者： lu jiang School of Translation Studies Jinan UniversityZhuhai 519070Guangdong ProvinceChina

In recent years,more and more directors of culture and tourism have taken part in the promotion of local cultural tourism by cross-dressing,talent shows,and pushing their limits on self-media *** study investigates short videos of Lingnan culture promoted by directors general and deputy directors general of the Culture,Radio,Television,Tourism,and Sports Bureau of counties and cities in Guangdong Province on social media by the method of multimodal critical discourse *** analysis of 33 videos shows that Lingnan culture is a domineering and confident culture,historical culture,graceful and elegant culture,and vibrant and active *** and confident culture is embedded in the utterances and behaviors of the directors general or deputy directors general in the *** culture is realized through the conversation with historical figures through time *** and elegant culture is constructed in the depiction of sceneries and the depiction of characters’*** and active culture is represented in the depiction of the characters’actional process and analytical process.

关键词： Lingnan culture Multimodal critical discourse analysis Promotional videos TikTok WeChat

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双桨双舵内倾船型的横甩失稳运动预报研究

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船舶力学 2024年第9期28卷 1307-1316页

作者：储纪龙顾民鲁江中国船舶科学研究中心江苏无锡214082

目前国际海事组织(IMO)已经发布了第二代完整稳性衡准骑浪/横甩直接稳性评估方法的最终指南,如何准确高效地数值预报骑浪/横甩运动是目前骑浪/横甩直接稳性评估方法中亟待解决的关键问题。本文构建一个纵荡-横荡-垂荡-横摇-纵摇-首摇六... 详细信息

目前国际海事组织(IMO)已经发布了第二代完整稳性衡准骑浪/横甩直接稳性评估方法的最终指南,如何准确高效地数值预报骑浪/横甩运动是目前骑浪/横甩直接稳性评估方法中亟待解决的关键问题。本文构建一个纵荡-横荡-垂荡-横摇-纵摇-首摇六自由度运动耦合的数学模型,该数学模型首先在纵荡-横荡-横摇-首摇四自由度操纵性数学模型基础上考虑垂荡和纵摇运动的影响,采用基于加强积分的切片法求解垂荡和纵摇运动的幅值和相位,可以有效解决尾浪中高航速船舶直接耐波性时域计算容易发散的问题;其次,船舶在波浪中的Froude-Krylov力和绕射力是通过对船体平均湿表面进行压力积分获得的。同时,在数学模型中还考虑非线性水动力导数、静水横倾产生的水动力和非线性横摇阻尼等因素。在螺旋桨推力和舵力模型中考虑由于波浪粒子速度和船舶速度共存产生的水动升力的影响,舵力模型中还加入了垂荡、纵摇运动对波浪中双舵实时出入水导致的舵力动态变化。最后,以双桨双舵的ONR内倾船型为研究对象,开展尾斜浪中骑浪/横甩数值预报,分析船-波的初始相对位置对船舶骑浪/横甩运动的影响。计算结果表明,文中建立的六自由度骑浪/横甩数学模型具有足够的计算精度,可以用于骑浪/横甩的直接稳性评估。

关键词：第二代完整稳性衡准直接稳性评估横甩内倾船

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外资进入的碳排放效应及其对碳达峰的影响

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气候变化研究进展 2024年第2期20卷 205-219页

作者：曹翔姜璐于洋海南大学国际商学院海口570228

在不断压缩外资准入“负面清单”的大背景下,进一步引进外资究竟会如何影响双碳目标的实现?为回答这一问题,使用2001—2019年省份-行业的碳排放数据,并结合《外商投资产业指导目录》以及《中西部地区外商投资优势产业目录》,构建双重差... 详细信息

在不断压缩外资准入“负面清单”的大背景下,进一步引进外资究竟会如何影响双碳目标的实现?为回答这一问题,使用2001—2019年省份-行业的碳排放数据,并结合《外商投资产业指导目录》以及《中西部地区外商投资优势产业目录》,构建双重差分模型研究了外资准入政策的碳排放效应、作用机制、异质性及其与碳达峰的关系。结果表明:外资准入政策显著降低了碳排放水平,且该政策主要通过促进能源结构清洁化实现碳减排;外资准入政策对东部地区碳排放无显著影响,对中部地区和北方地区碳排放具有显著的抑制作用,而对西部地区和南方地区碳排放有显著的促进作用;相较于高碳排放行业,该政策对非高碳排放行业的碳减排作用更为突出;拓展分析发现,外资进入规模与碳排放量存在着“倒U型”曲线关系,且中国绝大多数省份大多数行业尚未跨过拐点。因此,进一步放松外资准入政策、持续推进能源结构清洁化并根据地区及行业异质性制定差异化的“负面清单”等可助力双碳目标的实现。

关键词：外资准入政策碳排放双重差分法分省分行业 “倒U型”曲线

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伊伐布雷定在儿童心血管疾病中的应用进展

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中国当代儿科杂志 2024年第7期26卷 782-788页

作者：蒋露(综述) 孙慧超(审校) 重庆医科大学附属儿童医院心血管科/国家临床重点专科/儿童发育疾病研究教育部重点实验室/国家儿童健康与疾病临床医学研究中心/儿童发育重大疾病国家国际科技合作基地重庆400014

伊伐布雷定作为特异性I_(f)电流抑制剂,因其在降低心率的同时不影响心肌收缩力和血压,已广泛应用于成人慢性心力衰竭的治疗,并且在多种快速性心律失常中亦展现出良好的治疗效果。但伊伐布雷定在儿童心血管疾病的应用还有很多限制,该文... 详细信息

伊伐布雷定作为特异性I_(f)电流抑制剂,因其在降低心率的同时不影响心肌收缩力和血压,已广泛应用于成人慢性心力衰竭的治疗,并且在多种快速性心律失常中亦展现出良好的治疗效果。但伊伐布雷定在儿童心血管疾病的应用还有很多限制,该文就目前国内外关于伊伐布雷定治疗儿童心血管疾病的研究进展进行综述,以期为儿童心血管医生提供指导。

关键词：心力衰竭伊伐布雷定心律失常心脏移植儿童

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