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Effects of chronic exposure to nonylphenol on locomotor activity and social behavior in zebrafish(Danio rerio)

Journal of Environmental Sciences 2010年第9期22卷 1435-1440页

作者： Jigang Xia,Cuijuan Niu ,Xuejiao Pei Ministry of Education Key Laboratory of Biodiversity Science and Ecological Engineering,College of Life Sciences,beijing normal university,100875 beijing,china. [a] Ministry of Education Key Laboratory of Biodiversity Science Ecological Engineering College of Life Sciences Beijing Normal University 100875 Beijing China

Nonylphenol （NP）, a xenoestrogen ubiquitously found in aquatic ecosystems, is of high environmental concern. The present work assessed the effects of exposure to NP on locomotor activity and social behavior in male and female zebrafish （Danio rerio）, to evaluate the possible hazard of NP to fish behavior and to pursue a potential biomarker of NP contamination. Fish were randomly divided into six groups. Five groups were receiving 0.1, 1, 10, 50 and 100 μg/L nominal concentrations of NP for 60 days, respectively. A sixth control group was given the same treatment as the other five groups, but no NP. Locomotor activity, aggressive behavior, group preference and leaving shoal were examined. NP exposure showed marked influence on locomotor activity of the male zebrafish, whereas that of the female was not significantly affected by NP. Aggressive behavior and group preference were significantly affected by NP exposure in both male and female groups. Locomotor activity and aggressive behavior of the male and group preference of both male and female zebrafish were clearly inhibited at 100 μg/L NP. No significant alteration in leaving shoal was observed under NP exposure. The results suggested that changes in locomotor activity and aggressive behavior of the male and group preference of both male and female may be used as an ecologically relevant integrative biomarker of NP contamination.

关键词： chronic toxicity nonylphenol biomarker zebrafish

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Multiplicity of Periodic Solutions of Duffing Equations with Jumping Nonlinearities

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Acta Mathematicae Applicatae Sinica 2002年第3期18卷 513-522页

作者： Zai-hong WangDepartment of mathematics, Capital normal university, beijing 100037, china Department of mathematics Capital Normal University Beijing China

We provide sufficient conditions for the existence and multiplicity of subharrnonic solutions for Duffing's equations with jumping nonlinearities.

关键词： Periodic solution. Jumping nonlinearity PS-condition

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MAPK signal pathways in the regulation of cell proliferation in mammalian cells

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Cell Research 2002年第1期12卷 9-18页

作者： WEI ZHANG, Hui Tu LIU The Key Laboratory of Cell Proliferation and Regulation Biology of Ministry of Education, College of Life Sciences, beijing normal university, beijing 100875, china 1The Key Laboratory of Cell Proliferation and Regulation Biology of Ministry of Education College of Life Sciences Beijing Normal University Beijing 100875 China 1The Key Laboratory of Cell Proliferation and Regulation Biology of Ministry of Education College of Life Sciences Beijing Normal University Beijing 100875 China

MAPK families play an important role in complex cellular programs like proliferation, differentiation, development, transformation, and apoptosis. At least three MAPI(families have been characterized: extracellular signal-regulated kinase (ERK), Jun kinase (JNK/SAPK) and p38 MAPK. The above effects are fulfilled by regulation of cell cycle engine and other cell proliferation related proteins. In this paper we discussed their functions and cooperation with other signal pathways in regulation of cell proliferation.

关键词： MAPK ER.K JNK/SPAK p38 cell proliferation cross-talk.

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Solvation effects on brain uptakes of isomers of ^(99m)Tc brain imaging agents

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Chinese Science Bulletin 2002年第21期47卷 1786-1791页

作者： JIA Hongmei, MA Xiaohui, WANG Cunxin & LIU Boli1. Department of Chemistry, beijing normal university, beijing 100875, china 2. Center for Biomedical Engineering, beijing Polytechnic university, beijing 100022, china 1. Department of Chemistry Beijing Normal University Beijing 100875 China 2. Center for Biomedical Engineering Beijing Polytechnic University Beijing 100022 China

Analysis of electrostatic hydration free energies of the isomers of the 99mTc-BAT and 99mTc-DADT complexes is carried out using the computer simulation technique. The results show that not only a correlation exists between the logarithm of the brain uptake and the electrostatic hydration free energy for the isomers of 99mTc-brain radiopharmaceu-ticals, but also a linear relationship exists between the logarithm of the ratio of the brain uptake of the syn isomer to that of the anti one and the difference between the electrostatic hydration free energy of the syn-isomer and that of the anti one. Furthermore, the investigation on the important factors influencing the brain uptakes of 99mTc-radiophar-maceuticals and the reasons of the different biodistribution of the isomers of the 99mTc-complexes is explored at the molecular level. The results may provide a reference for the rational drug design of brain imaging agents.

关键词： 99mTc-brain imaging agent isomer brain uptake electro-static hydration free energy.

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Quenched moderate deviations principle for random walk in random environment

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Science china mathematics 2010年第8期53卷 1947-1956页

作者： HONG WenMing 1 & WANG HuaMing 1,2 1 Key Laboratory of mathematics and Complex Systems of Ministry of Education & School of Mathematical Sciences,beijing normal university,beijing 100875,china 2 Department of Basic Courses,Business College,beijing Union university,beijing 100025,china 1. Key Laboratory of mathematics and Complex Systems of Ministry of Education & School of Mathematical Sciences Beijing Normal University Beijing 100875 China2. Department of Basic Courses Business College Beijing Union University Beijing 100025 China

We derive a quenched moderate deviations principle for the one-dimensional nearest random walk in random environment,where the environment is assumed to be stationary and *** approach is based on hitting time decompos... 详细信息

关键词： random walk in random environment moderate deviations principle hitting time

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Relativist ic Corrections to the Thermal Sunyaev-Zel'dovich Power Spectrum

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Chinese Journal of Astronomy and Astrophysics 2003年第5期3卷 410-414页

作者： Hai-Ning LiNational Astronomical Observatories, Chinese Academy of Sciences, beijing 100012 lhnDepartment of Astronomy, beijing normal university, beijing 100875 National Astronomical Observatories CAS NAOC Beijing 100012 China []Department of Astronomy Beijing Normal University Beijing 100875

We present a quantitative estimate of the relativistic corrections to thethermal SZ power spectrum produced by the energetic electrons in massive clusters. The correctionsare well within 10% for current experiments with working frequencies below ν 350 GHz. Moreover, the corrections appear to be slightlysmaller at higher l or smaller angular scales. We conclude that there is no need to include therelativistic corrections in the theoretical study of the SZ power spectrum especially at lowfrequencies unless the SZ power spectrum is used for precision cosmology.

关键词： cosmic microwave background cosmology: theory galaxies: clusters: general

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Attractive Behavior for a Logistic Population with Age-Dependent Reproduction

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Communications in Nonlinear Science and Numerical Simulation 1998年第1期3卷 6+8+10+7+9-6+8+10+7+9页

作者： Haiyang HUANG and Laifu LIU (Dept. of Math. beijing normal university, beijing, 100875, china) E-mail: hhywsg@*** Department of mathematics Beijing Normal University Beijing 100875 China

１ＩｎｔｒｏｄｕｃｔｉｏｎＡｓｗｅｋｎｏｗ，ｔｈｅＬｏｇｉｓｔｉｃｍｏｄｅｌｆｏｒｍｅｄＮ′＝ｒ（１－Ｎ／Ｋ）Ｎｗａｓａｆｕｎｄａｍｅｎｔａｌｍｏｄｅｌｏｆｂｉｏｌｏｇｉｃａｌｐｏｐｕｌａｔｉｏｎｄｙｎａｍｉｃｓｗ... 详细信息

１ＩｎｔｒｏｄｕｃｔｉｏｎＡｓｗｅｋｎｏｗ，ｔｈｅＬｏｇｉｓｔｉｃｍｏｄｅｌｆｏｒｍｅｄＮ′＝ｒ（１－Ｎ／Ｋ）Ｎｗａｓａｆｕｎｄａｍｅｎｔａｌｍｏｄｅｌｏｆｂｉｏｌｏｇｉｃａｌｐｏｐｕｌａｔｉｏｎｄｙｎａｍｉｃｓｗｉｔｈｄｅｎｓｉｔｙｄｅｐｅｎｄｅ...

关键词： Logistic model age dependence attractive behavior

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COSMIC PLASMA DYNAMO

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空间科学学报 2002年第4期22卷 289-299页

作者： YANG Zhiliang(Astronomy Department, beijing normal university, beijing 100875) AstronomyDepartment BeijingNormalUniversity 北京 100875

A new dynamo model based on the polarization of plasma is presented in this *** the Maxwell equations in a moving medium, a magnetization vector can be causedwith Rongon current. The steady solar magnetic field is solved from the equations. Onthe assumption that the meridianal flow is ignored, the distribution of magnetic field isput out. In the model, there is no additional parameter considered. The intensity ofmagnetic field inside the sun ranges from 1-6T. The surface magnetic field around thepole is in the order of 1×10-3T, at low latitude the calculated surface magnetic fieldhas the order of 1×10-2 T. The maximum magnetic field is around 30° in latitude.

关键词：太阳风发动机模型等离子体磁场强度

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Some Characterizations of Weighted Herz-type Hardy Spaces and Their Applications

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Acta Mathematica Sinica,English Series 1997年第1期13卷 45-58页

作者： Lu Shanzhen (Department of mathematics,beijing normal university,beijing,100875,china)(E-mail:lusz@***)Yang Dachun (Department of mathematics,beijing normal university,Beijin9,100875,china)(E-mail:dcyang@***) Department of mathematics Beijing Normal University 100875 Beijing China

In this paper,the authors first establish some new real-variable characterizations of Herz- type Hardy spaces Hqα,p（ω1;ω2）and HKqα,P（ω1;ω2）,where ω1,ω2 ∈A1-weight,1 详细信息

In this paper,the authors first establish some new real-variable characterizations of Herz- type Hardy spaces Hqα,p（ω1;ω2）and HKqα,P（ω1;ω2）,where ω1,ω2 ∈A1-weight,1

关键词： Herz space Herz-type Hardy space Potential operator

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Weighted estimates for the multilinear singular integral operators with non-smooth kernels

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Science china mathematics 2011年第3期54卷 587-602页

作者： HU GuoEn1 & LU ShanZhen2 1Department of Applied mathematics, Zhengzhou Information Science and Technology Institute, Zhengzhou 450002, china 2Department of mathematics, beijing normal university, beijing 100875, china 1. Department of Applied mathematics Zhengzhou Information Science and Technology Institute Zhengzhou 450002 China2. Department of Mathematics Beijing Normal University Beijing 100875 China

In this paper, by sharp function estimates and certain weak type endpoint estimates, the authors establish some weighted norm inequalities with Ap weights for the multilinear singular integral operators with non-smoot... 详细信息

关键词： approximation to the identity weighted norm inequality singular integral operator non-smooth kernel Calderón-Zygmund decomposition

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