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Collaborative positioning for swarms:A brief survey of vision,LiDAR and wireless sensors based methods

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Defence Technology（防务技术） 2024年第3期33卷 475-493页

作者： Zeyu Li Changhui jiang xiaobo Gu Ying Xu Feng zhou Jianhui cui College of Geodesy and Geomatics Shandong University of Science and TechnologyQingdao266590China Geoloc Laboratory Universite Gustave EiffelParis77454France School of Automation Guangdong University of TechnologyGuangzhou510006China

As positioning sensors,edge computation power,and communication technologies continue to develop,a moving agent can now sense its surroundings and communicate with other *** receiving spatial information from both its environment and other agents,an agent can use various methods and sensor types to localize *** its high flexibility and robustness,collaborative positioning has become a widely used method in both military and civilian *** paper introduces the basic fundamental concepts and applications of collaborative positioning,and reviews recent progress in the field based on camera,LiDAR(Light Detection and Ranging),wireless sensor,and their *** paper compares the current methods with respect to their sensor type,summarizes their main paradigms,and analyzes their evaluation ***,the paper discusses the main challenges and open issues that require further research.

关键词： Collaborative positioning Vision LiDAR Wireless sensors Sensor fusion

CA IX-targeted Ag_(2)S quantum dots bioprobe for NIR-II imaging-guided hypoxia tumor chemo-photothermal therapy

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Journal of Pharmaceutical Analysis 2024年第6期14卷 878-888页

作者： Xinyue cui Zhuang Hu Ruihan Li peng jiang Yongchang Wei Zilin Chen Department of Radiation and Medical Oncology Zhongnan Hospital of Wuhan University and School of Pharmaceutical SciencesWuhan UniversityWuhan430071China Key Laboratory of Combinatorial Biosynthesis and Drug Discovery Ministry of EducationHubei Province Engineering and Technology Research Center for Fluorinated PharmaceuticalsWuhan430071China

Hypoxia is the common characteristic of almost all solid tumors,which prevents therapeutic drugs from reaching the ***,the development of new targeted agents for the accurate diagnosis of hypoxia tumors is widely *** carbonic anhydrase IX(CA IX)is abundantly distributed on the hypoxia tumor cells,it is considered as a potential tumor biomarker.4-(2-Aminoethyl)benzenesulfonamide(ABS)as a CA IX inhibitor has inherent inhibitory activity and good targeting *** this study,Ag_(2)S quantum dots(QDs)were used as the carrier to prepare a novel diagnostic and therapeutic bioprobe(Ag_(2)S@polyethylene glycol(PEG)-ABS)through ligand exchange and amide condensation ***_(2)S@PEG-ABS can selectively target tumors by surface-modified ABS and achieve accurate tumor imaging by the near infrared-II(NIR-II)fluorescence characteristics of Ag_(2)S *** modification of Ag_(2)S QDs greatly improves its water solubility and stability,and therefore achieves high photothermal stability and high photothermal conversion efficiency(PCE)of 45.17%.Under laser irradiation,Ag_(2)S@PEG-ABS has powerful photothermal and inherent antitumor combinations on colon cancer cells(CT-26)in *** also has been proved that Ag_(2)S@PEG-ABS can realize the effective treatment of hypoxia tumors in vivo and show good ***,it is a new efficient integrated platform for the diagnosis and treatment of hypoxia tumors.

关键词： CA IX-targeted Hypoxia tumor combination therapy NIR-II imaging Photothermal effect

Antecedent snowmelt and orographic precipitation contributions to water supply of Pakistan disastrous floods,2022

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Advances in Climate Change Research 2024年第3期15卷 419-430页

作者： Yan WANG peng cui Chen-Di ZHANG Guo-Tao ZHANG Jian-Sheng HAO Xu YUAN Yao-Zhi jiang Lu WANG Key Laboratory of Land Surface Pattern and Simulation Institute of Geographic Sciences and Natural Resources ResearchChinese Academy of SciencesBeijing 100101China Key Laboratory of Mountain Hazards and Earth Surface Process Institute of Mountain Hazards and EnvironmentChinese Academy of SciencesChengdu 610299China Polar and Marine Research Institute College of Harbor and Coastal EngineeringJimei UniversityXiamen 361021China School of Resources and Environment University of Electronic Science and Technology of ChinaChengdu 610054China Hebei Province Tangshan Caofeidian Meteorological Bureau Tangshan 063000China

In 2022,the Pakistan witnessed the hottest spring and wettest summer in *** devastating floods inundated a large portion of Pakistan and caused enormous ***,the primary water source and its contributions to these unprecedented floods remain *** on the reservoir inflow measurements,Multi-Source Weighted-Ensemble Precipitation(MSWEP),the fifth generation ECMWF atmospheric reanalysis(ERA5)products,this study quantified the contributions of monsoon precipitation,antecedent snow-melts,and orographic precipitation enhancement to floods in *** found that the Indus experienced at least four inflow up-rushes,which was mainly supplied by precipitation and snowmelt;In upper Indus,abnormally high temperature continued to influence the whole summer and lead to large amounts of snowmelts which not only was a key water supply to the flood but also provided favorable soil moisture conditions for the latter *** July,the snowmelt has higher contributions than the precipitation to the streamflow of Indus River,with contribution value of more than 60%.Moreover,the snowmelt could still supply 20%-40%water to the lower Indus in July and August;The leading driver of 2022 mega-floods over the southern Pakistan in July and August was dominated by the precipitation,where terrain disturbance induced precipitation account to approximately 33%over the southern *** results help to understand the mechanisms of flood formation,and to better predict future flood risks over complex terrain regions.

关键词： Extreme heavy rainfall Snowmelt Orographic precipitation Floods Pakistan

TRPM2 Mediates Hepatic Ischemia–Reperfusion Injury via Ca^(2+) -Induced Mitochondrial Lipid Peroxidation through Increasing ALOX12 Expression

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Research 2024年第1期2023卷 351-368页

作者： Cheng Zhong Jing Yang Yiyin Zhang Xiaoxiao Fan Yang Fan Ning Hua Duguang Li Shengxi Jin Yirun Li peng Chen Yongle Chen xiaobo Cai Yi Zhang Linhua jiang Wei Yang Peilin Yu Hui Lin Department of General Surgery Sir Run Run Shaw HospitalSchool of MedicineZhejiang UniversityHangzhouP.R.China Department of Biophysics and Department of Neurology of the Fourth Affiliated Hospital Zhejiang University School of MedicineHangzhou 310000P.R.China Department of Physiology and Pathophysiology and Sino-UK Joint Laboratory of Brain Function and Injury of Henan Province Xinxiang Medical University453003 XinxiangHenanP.R.China School of Biomedical Sciences Faculty of Biological SciencesUniversity of LeedsLS29JT LeedsUK Department of Toxicology and Department of Medical Oncology of Second Affiliated Hospital Zhejiang University School of MedicineHangzhouP.R.China Zhejiang Engineering Research Center of Cognitive Healthcare Sir Run Run Shaw HospitalSchool of MedicineZhejiang UniversityHangzhou 310020P.R.China College of Biomedical Engineering and Instrument Science Zhejiang UniversityHangzhou 310058P.R.China

Hepatic ischemia–reperfusion(IR)injury is a serious clinical problem that complicates liver resection and *** recent advances in understanding of the pathophysiology of hepatic IR injury,effective interventions and therapeutics are still ***,we examined the role of transient receptor potential melastatin 2(TRPM2),a Ca^(2+)-permeable,non-selective cation channel,in mediating hepatic IR *** data showed that TRPM2 deficiency attenuated IR-induced liver dysfunction,inflammation,and cell death in ***,RNA sequencing analysis indicated that TRPM2-induced IR injury occurs via ferroptosis-related ***,as a ferroptosis inducer,(1S,3R)-RSL3 treatment induced mitochondrial dysfunction in hepatocytes and a TRPM2 inhibitor suppressed ***,TRPM2-mediated calcium influx caused mitochondrial calcium accumulation via the mitochondrial Ca^(2+)-selective uniporter and increased the expression level of arachidonate 12-lipoxygenase(ALOX12),which results in mitochondrial lipid peroxidation during hepatic IR ***,hepatic IR injury-induced ferroptosis was obviously relieved by a TRPM2 inhibitor or calcium depletion,both in vitro and in ***,these findings demonstrate a crucial role for TRPM2-mediated ferroptosis in hepatic IR injury via increased Ca^(2+)-induced ALOX12 expression,indicating that pharmacological inhibition of TRPM2 may provide an effective therapeutic strategy for hepatic IR injury-related diseases,such as during liver resection and transplantation.

关键词： TRPM2 Lipid Hepatic

Prophylactic treatment of Lacticaseibacillus paracasei K56 ameliorates asthma by regulating short-chain fatty acid production and Treg differentiation

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Food Science and Human Wellness 2024年

作者： Jiaqi cui Yanfei Hong Wei-Hsien Liu Wen Zhao Xinmei Nan Xuekai Shang Yalan Li Haotian Feng Qiuyue jiang Weilian Hung Guiying peng Inner Mongolia Yili Industrial Group Co.， Ltd. Department of Immunology and Microbiology， School of Life Sciences， Beijing University of Chinese Medicine

Many studies have shown that the development of allergic asthma is associated with intestinal microbiota dysbiosis. Based on the gut-lung axis theory， probiotic intervention may be a potential strategy for respiratory diseases. Lacticaseibacillus paracasei K56 was reported to regulate gut microbiota in mice. However， its effect on allergic asthma has not been reported. In this study， we investigated the effect of the K56 on ovalbumin-induced asthma and its possible mechanisms. Our results showed that K56 reduced asthma symptoms and inflammatory cell infiltration in the lung of asthmatic mice. And K56 regulated the differentiation of helper T cells in the lung and intestine. Results from 16S rRNA gene sequencing showed that K56 prophylaxis significantly elevated the richness of Akkermansia and Burkholderia. Meanwhile， K56 abrogated the decrease in the levels of short-chain fatty acids (SCFAs) in the feces. In addition， a rebound in the mRNA expression of the SCFA receptors was observed after K56 prophylaxis. Notably， the regulatory T cell (Treg) frequencies and the FFAR3 levels were positively correlated. These results suggest that K56 could attenuate asthma， possibly by modulating the intestinal microbiota and regulating Treg differentiation through SCFA metabolized. Our study showed that K56 may be used as a probiotic to prevent pulmonary inflammation and dysbiosis of the intestinal microbiota in allergic asthma.

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Homoharringtonine promotes heart allograft acceptance by enhancing regulatory T cells induction in a mouse model

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Chinese Medical Journal 2024年第12期137卷 1453-1464页

作者： Xia Qiu Hedong Zhang Zhouqi Tang Yuxi Fan Wenjia Yuan Chen Feng Chao Chen pengcheng cui Yan cui Zhongquan Qi Tengfang Li Yuexing Zhu Liming Xie Fenghua peng Tuo Deng Xin jiang Longkai peng Helong Dai Medical College Guangxi UniversityNanningGuangxi 530004China Department of Kidney Transplantation Center of Organ TransplantationThe Second Xiangya Hospital of Central South UniversityChangshaHunan 410011China National Clinical Research Center for Metabolic Diseases and Department of Metabolism and EndocrinologyThe Second Xiangya Hospital of Central South UniversityChangshaHunan 410011China Department of Organ Transplantation The Fifth Clinical Medical College of Henan University of Chinese Medicine(Zhengzhou People’s Hospital)ZhengzhouHenan 450000China

Background:Homoharringtonine(HHT)is an effective anti-inflammatory,anti-viral,and anti-tumor protein synthesis inhibitor that has been applied ***,we explored the therapeutic effects of HHT in a mouse heart transplant ***:Healthy C57BL/6 mice were used to observe the toxicity of HHT in the liver,kidney,and hematology.A mouse heart transplantation model was constructed,and the potential mechanism of HHT prolonging allograft survival was evaluated using Kaplan-Meier analysis,immunostaining,and bulk RNA sequencing *** HHT-T cell crosstalk was modeled ex vivo to further verify the molecular mechanism of HHT-induced regulatory T cells(Tregs)***:HHT inhibited the activation and proliferation of T cells and promoted their apoptosis ex *** of 0.5 mg/kg HHT for 10 days significantly prolonged the mean graft survival time of the allografts from 7 days to 48 days(P<0.001)without non-immune *** allografts had long-term survival after continuous HHT treatment for 28 *** significantly reduced lymphocyte infiltration in the graft,and interferon-γ-secreting CD4^(+)and CD8^(+)T cells in the spleen(P<0.01).HHT significantly increased the number of peripheral Tregs(about 20%,P<0.001)and serum interleukin(IL)-10 *** downregulated the expression of T cell receptor(TCR)signaling pathway-related genes(CD4,H2-Eb1,TRAT1,and CD74)and upregulated the expression of IL-10 and transforming growth factor(TGF)-βpathway-related genes and Treg signature genes(CTLA4,Foxp3,CD74,and ICOS).HHT increased CD4^(+)Foxp3^(+)cells and Foxp3 expression ex vivo,and it enhanced the inhibitory function of inducible ***:HHT promotes Treg cell differentiation and enhances Treg suppressive function by attenuating the TCR signaling pathway and upregulating the expression of Treg signature genes and IL-10 levels,thereby promoting mouse heart allograft *** findings may have therapeutic implications for organ tr

关键词： Heart transplantation Homoharringtonine Immunosuppressive agents T-lymphocytes,Regulatory Graft acceptance

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支持增量式编程的多模态网络环境

电子学报 2024年第4期52卷 1230-1238页

作者：崔子熙田乐崔鹏帅胡宇翔伊鹏邬江兴中国人民解放军战略支援部队信息工程大学信息技术研究所河南郑州450001

当前,多模态网络编程模型与底层硬件紧耦合、强相关,导致网络程序呈现扁平化和单片化特征.因此,持续开发模态程序效率低下且极易出错,制约了网元设备的可用性和可靠性.为此,本文提出面向多模态网络的编程环境(PINet’s Programming Envi... 详细信息

当前,多模态网络编程模型与底层硬件紧耦合、强相关,导致网络程序呈现扁平化和单片化特征.因此,持续开发模态程序效率低下且极易出错,制约了网元设备的可用性和可靠性.为此,本文提出面向多模态网络的编程环境(PINet’s Programming Environment,PPE),支持增量式开发网络协议与功能.基于“巨型交换机”思想,PPE提出了一种平台无关的编程模型及语言,支持模块化编程和跨平台移植,通过模块单元的灵活组合提高网络程序的开发效率.同时,针对上述模型设计了前后端分离的编译系统框架.该系统自动化解析并组合分布式的模态程序,通过优化报文处理逻辑自动适配硬件资源约束.实验结果表明,在不影响硬件性能的基础上,PPE能够降低20%的程序开发量,同时引入编译时延和资源开销在合理范围内.

关键词：编程模型多模态网络可编程数据平面模块化增量式编程网络模态

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钢筋混凝土环境中负载型阻锈剂的研究进展

材料导报 2024年第2期38卷 104-117页

作者：徐宁杨恒熊传胜崔征蒋鹏刘璨南京水利科学研究院水文水资源与水利工程科学国家重点实验室青岛理工大学土木工程学院南京瑞迪高新技术有限公司

阻锈剂技术是抑制混凝土中钢筋锈蚀的重要途径，但传统阻锈剂的应用仍然面临功能单一、与混凝土的兼容性不佳、环保性和有效性难以兼顾等问题。将阻锈剂装载入载体中，以载体负载阻锈剂(Carrier-loaded corrosion inhibitor, CLCI)的形... 详细信息

阻锈剂技术是抑制混凝土中钢筋锈蚀的重要途径，但传统阻锈剂的应用仍然面临功能单一、与混凝土的兼容性不佳、环保性和有效性难以兼顾等问题。将阻锈剂装载入载体中，以载体负载阻锈剂(Carrier-loaded corrosion inhibitor, CLCI)的形式将阻锈剂“间接”掺入混凝土，能够在避免阻锈剂原有缺陷的基础上，发挥载体的特有功能。本文围绕CLCI的离子固化、缓释效应、智能响应、pH自免疫系统、载体吸附效应等功能机制，结合CLCI对水泥基材料性能的影响，系统综述了CLCI的研究进展。最后，对其在混凝土中的研究和应用进行了展望，并提出了需要解决的问题，以期为CLCI在混凝土工程中的应用提供更多可能性。

关键词：负载型阻锈剂钢筋混凝土腐蚀智能响应缓释力学性能

Er^(3+)/Nd^(3+)/Tm^(3+)共掺碲酸盐玻璃近红外发射和能量传递机理

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光谱学与光谱分析 2024年第4期44卷 1171-1176页

作者：陈安民马飞云崔令江张鹏王传杰威海长和光导科技有限公司威海市光纤预制棒工程技术研究中心山东威海264200 哈尔滨工业大学(威海)材料科学与工程学院山东威海264209 宏安集团有限公司技术部山东威海264200

为满足通信网络飞速发展对密集波分复用系统(DWDM)传输容量需求的不断增加,对DWDM系统核心器件掺铒光纤放大器(EDFA)性能的要求也越来越高。碲酸盐玻璃因其具有稀土离子溶解度高,声子能量低和高折射率等优点已成为替代传统掺铒石英光纤... 详细信息

为满足通信网络飞速发展对密集波分复用系统(DWDM)传输容量需求的不断增加,对DWDM系统核心器件掺铒光纤放大器(EDFA)性能的要求也越来越高。碲酸盐玻璃因其具有稀土离子溶解度高,声子能量低和高折射率等优点已成为替代传统掺铒石英光纤的理想材料。掺稀土碲酸盐玻璃可以作为宽带光纤放大器的理想增益介质来实现信号有效放大,因此提高掺铒碲酸盐玻璃光谱性能并拓展其放大带宽对DWDM系统扩容具有重要意义。通过Er^(3+)、Nd^(3+)和Tm^(3+)共同掺杂提高碲酸盐玻璃的放大带宽以获得超宽带发光。Er^(3+)、Nd^(3+)和Tm^(3+)分别通过跃迁产生1.55、1.34和1.85μm波段的发光,且三个近红外发射波段基本相邻。采用三种离子共掺的方式,通过离子间发生能量传递(ET)来实现碲酸盐玻璃在连续光谱中的发光。在TeO_(2)-WO_(3)-ZnO-Na_(2)O-Er_(2)O_(3)碲酸盐玻璃中,先进行Er^(3+)/Nd^(3+)掺杂,分析Er^(3+)/Nd^(3+)间能量传递机理,得到Er_(2)O_(3)、Nd_(2)O_(3)掺杂浓度分别为1、0.1 mol%时玻璃发光强度较佳。再进行不同Tm^(3+)浓度下的Er^(3+)/Nd^(3+)/Tm^(3+)三种离子掺杂,最后采用高温熔融退火法制备得到热稳定性能良好的Er^(3+)/Nd^(3+)/Tm^(3+)掺杂碲酸盐玻璃。Er^(3+)、Nd^(3+)和Tm^(3+)间发生能量传递,在1250~2100 nm范围内产生了发光中心为1.3、1.5和1.8μm的三个波段发光,覆盖了整个O、E、S、C、L和U波段。1.5μm处的荧光半高宽(FWHM)增加到131.68 nm,1.8μm处的FWHM高达251.75 nm。详细分析了三种稀土掺杂时稀土离子之间的能量传递过程机理。光谱结果表明,当Er_(2)O_(3)、Nd_(2)O_(3)、Tm_(2)O_(3)掺杂浓度分别为1、0.1、0.2 mol%时,Er^(3+)/Nd^(3+)/Tm^(3+)三掺碲酸盐玻璃是超宽带光纤放大器设计的一种有效材料。

关键词：碲酸盐玻璃近红外发光能量传递热稳定性能