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Early-phase changes of P-wave characteristics after circumferential pulmonary vein isolation

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Chinese Medical Journal 2013年第14期126卷 2607-2612页

作者： ZHAO Liang jiang wei-feng zhou Li LIUXu Department of Cardiology Shanghai Chest Hospital Shanghai Jiao Tong University Shanghai 200030 China

Background Circumferential pulmonary vein isolation （CPVI）, as the basal ablation strategy for treating atrial fibrillation （AF）, not only isolates the connection between the left atrium （LA） and the pulmonary veins （PVs）, but also induces extensive atrial endocardia damage. This could have an effect on the sinus pulse conduction in the LA and subsequently result in changes of P-wave characteristics of surface electrocardiogram （ECG）. Methods Fifty consecutive patients underwent CPVI for symptomatic drug-refractory paroxysmal AF. The 12-lead ECGs were recorded one day before CPVI and seven days after CPVI at sinus rhythm by a standard resting ECG device. Measured characteristics of the P-wave consisted of P-wave duration （PWD）, P-wave amplitude （PWA）, P-wave polarity （PWP）, P-wave notch, P-wave dispersion and P-wave index. Results After CPVI, a prevalent decrease of PWD, PWA, and P-wave dispersion was observed; a transition of P-wave polarity was observed in the leads of III, aVL and aVF. The rate of P-wave notch decreased significantly in all leads, especially in the leads of II, III, aVF and V3. Patients with sinus rhythm had a shorter P-wave dispersion and P-wave index and had a lower rate of P-wave notch compared with the patients with recurrent atrial tachyarrhythmia. Conclusion Observations from using the surface ECG showed that CPVI has instant effects on the electrical conduction in the LA, and several changes of P-wave characteristics associated with development olAF are improved by CPVI.

关键词： P-wave atrialfibrillation circumferentialpulmonary vein isolation

Relativistic Density-Dependent Hartree Approach for Nuclear Matter in the Chiral-Symmetry-Breaking Model

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Chinese Physics Letters 1996年第6期13卷 416-419页

作者： jiang wei-zhou ZHU Zhi-yuan QIU Xi-jun Shanghai Institute of Nuclear Research Chinese Academy of SciencesShanghai 201800 Department of Physics Shanghai UniversityShanghai 201800

A relativistic density-dependent Hartree approach in the chiral-symmetry-breaking field model has been developed for nuclear *** coupling constants of the relativistic Hartree-Lagrangian are made density dependence and obtained from the relativistic Brueckner-Bethe-Goldstone results of nuclear *** calculated saturation nuclear density,binding-energy and compressibility for nuclear matter are close to the empirical ones.

关键词： Hartree relativistic Chiral

Neutron Halos in the Excited States of Spherical Nuclei Near the β-Stable Line

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Communications in Theoretical Physics 2002年第10期38卷 470-474页

作者： REN Zhong-zhou jiang wei-zhou CAI Xiang-zhou ZHU Zhi-Yuan SHEN Wen-Qing Department of Physics Nanjing University Nanjing 210093 China Shanghai Institute of Nuclear Research the Chinese Academy of Sciences Shanghai 201800 China Center of Theoretical Nuclear Physics National Laboratory of Heavy Ion Accelerator Lanzhou 730000 China Shanghai Institute of Nuclear Research the Chinese Academy of Sciences Shanghai 201800 China Shanghai Institute of Nuclear Research the Chinese Academy of Sciences Shanghai 201800 China Center of Theoretical Nuclear Physics National Laboratory of Heavy Ion Accelerator Lanzhou 730000 China Shanghai Institute of Nuclear Research the Chinese Academy of Sciences Shanghai 201800 China Center of Theoretical Nuclear Physics National Laboratory of Heavy Ion Accelerator Lanzhou 730000 China

The newly discovered neutron halos in the excited states of nuclei 12B, 13C, and 209pb are studied by therelativistic mean-field theory. The calculated binding energies are very close to the experimental ones. The experimentally extracted root-mean-square radii of the last neutron with different occupations in nuclei are well reproduced bycalculations. New candidates for the neutron halos in excited states are predicted and are useful for further search ofneutron halos in the excited states of stable nuclei.

关键词： neutron halo, excited states, relativistic mean-field theory

Intermediate Mass Dilepton Production in an Expanding Baryon-rich Quark--Gluon Matter

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Chinese Physics Letters 2001年第2期18卷 199-201页

作者： HE Ze-Jun jiang wei-zhou zhou Wen-Jie ZHANG Jia-Ju Center of Theoretical Nuclear Physics National Laboratory of Heavy Ion AcceleratorLanzhou 730000 Shanghai Institute of Nuclear Research Chinese Academy of SciencesShanghai 201800

The intermediate mass dileptons from the quark phase,secondary hadronic processes and background sources have been studied based on a relativistic hydrodynamic *** to the effect of the phase boundary on the evolution of the system the contribution from the quark phase is much more important than that from secondary processes and is even comparable with that from background *** leads to a spectrum without the obvious humps of the hadronic phase contribution and the yield increasing with the incident energy of colliding *** is shown that the enhancement of dileptons is a signature for the formation of the quark--gluon plasma.

关键词： quark signature relativistic

Analysis of the role of dihydromyricetin derived from vine tea(Ampelopsis grossedentata)on multiple myeloma by activating STAT1/RIG-I axis

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Oncology Research 2024年第8期32卷 1359-1368页

作者： wei jiang MEI zhou Department of Hematology Shaoxing Shangyu People’s HospitalShaoxing312000China Department of Hematology Zhuji People’s HospitalShaoxing311800China

Multiple myeloma(MM)is a plasma cell malignancy and remains incurable as it lacks effective curative approaches;thus,novel therapeutic strategies are desperately *** study aimed to explore the therapeutic role of dihydromyricetin(DHM)in MM and explore its *** MM and normal plasma samples,human MM cell lines,and normal plasma cells were used for in vitro *** counting kit-8(CCK-8),flow cytometry,and trans-well assays were performed for the assessment of cell viability,apoptosis,migration,and invasion,*** real-time polymerase chain reaction(qRT-PCR)was employed to assess the mRNA expression of signal transducer and activator of transcription 1(STAT1)and retinoic acid-inducible gene I(RIG-I).Western blotting was employed to assess E-cadherin,N-cadherin,signal transducer,STAT1,p-STAT1,and RIG-I protein expression.A tumor xenograft model was used for in vivo ***,dihydromyricetin(DHM)dose-dependently restrained viability,apoptosis,migration,and invasion,and facilitated apoptosis of U266 *** DHM treatment,the Ecadherin level was increased and the N-cadherin level was decreased in U266 and RPMI-8226 cells,suggesting the inhibitory effects of DHM on epithelial-mesenchymal transition(EMT)in ***,the levels of p-STAT1/STAT1 and RIG-I were down-regulated in ***,the STAT1 inhibitor fludarabine undid the suppressive effect of DMH on the malignant characteristics of U266 ***,DHM inhibited MM tumor growth and EMT,and activated STAT1/RIG-I pathway in ***,this study first revealed that DHM can restrain EMT and tumor growth in MM by activating STAT1/RIG-I signaling,which provides a novel drug for the treatment of MM.

关键词： Dihydromyricetin Multiple myeloma Epithelial-mesenchymal transition Tumor growth

C-CORE:Clustering by Code Representation to Prioritize Test Cases in Compiler Testing

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Computer Modeling in Engineering & Sciences 2024年第5期139卷 2069-2093页

作者： wei zhou Xincong jiang Chuan Qin School of Electronic Information and Electrical Engineering Shanghai Jiao Tong UniversityShanghai200240China Hikvision Research Institute Hangzhou Hikvision Digital Technology Co.Ltd.Hangzhou310051China

Edge devices,due to their limited computational and storage resources,often require the use of compilers for program ***,ensuring the security and reliability of these compilers is of paramount importance in the emerging field of edge *** widely used testing method for this purpose is fuzz testing,which detects bugs by inputting random test cases into the target ***,this process consumes significant time and *** improve the efficiency of compiler fuzz testing,it is common practice to utilize test case prioritization *** researchers use machine learning to predict the code coverage of test cases,aiming to maximize the test capability for the target compiler by increasing the overall predicted coverage of the test ***,these methods can only forecast the code coverage of the compiler at a specific optimization level,potentially missing many optimization-related *** this paper,we introduce C-CORE(short for Clustering by Code Representation),the first framework to prioritize test cases according to their code representations,which are derived directly from the source *** approach avoids being limited to specific compiler states and extends to a broader range of compiler ***,we first train a scaled pre-trained programming language model to capture as many common features as possible from the test cases generated by a *** this pre-trained model,we then train two downstream models:one for predicting the likelihood of triggering a bug and another for identifying code representations associated with ***,we cluster the test cases according to their code representations and select the highest-scoring test case from each cluster as the high-quality test *** reduction in redundant testing cases leads to time *** evaluation results reveal that code representations are better at distinguishing test capabilities,and C-CORE significantly enhanc

关键词： Compiler testing test case prioritization code representation

Dilepton Production in an Expanding Hot Baryon-Rich Quark-Gluon Matter

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Chinese Physics Letters 1999年第12期16卷 879-881页

作者： jiang wei-zhou HE Ze-jun ZHU Zhi-yuan ZHANG Jia-ju Center of Theoretical Nuclear Physics National Laboratory of Heavy Ion AcceleratorLanzhou 730000 Institute of Nuclear Research Chinese Academy of SciencesShanghai 201800

Under thermodynamic equilibrium, the initial values of the quark-gluon system from relativistic nucleus-nucleus collisions are obtained. From these initial values we have studied the dilepton production on the basis of the relativistic hydrodynamic model, and found that with increasing incident energy a characteristic plateau indicating the formation of the quark-gluon plasma appears in the total yield.

关键词： relativistic quark lepton

Dilepton Production in an Expanding Hot Baryon-Rich Quark-Gluon Matter

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Chinese Physics Letters 1999年第4期16卷 259-261页

作者： He Ze-jun ZHANG Jia-ju jiang wei-zhou QIU Xi-jun LIU Bo Center of Theoretical Nuclear Physics National Laboratory of Heavy Ion AcceleratorLanzhou 730000 Institute of Nuclear Research Chinese Academy of SciencesShanghai 201800 Institute of High Energy Chinese Academy of SciencesBeijing 100039

From the full stopping scenario,a relativistic hydrodynamic model describing the evolution of the baryon-rich quark-gluon matter fire-cylinder has been *** on it,the rapidity Distribution of dileptons with intermediate invariant masses has been *** is found that the quark phase gives the dominant contribution to the dilepton spectrum due to the influence of the phase boundary on the evolution of the system,especially the dilepton yield is strongly suppressed with the increasing rapidity.

关键词： quark lepton invariant

Differential Game Model of Resource Extraction with Continuous and Dynamic Updating

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Journal of the Operations Research Society of China 2024年第1期12卷 51-75页

作者： Ovanes Petrosian Tihomirov Denis jiang-Jing zhou Hong-wei Gao School of Mathematics Harbin Institute of TechnologyHarbin150001HeilongjiangChina School of Automation Qingdao UniversityQingdao266071ShandongChina Faculty of Applied Mathematics and Control Processes Saint-Petersburg State UniversitySaint PetersburgRussia National Research University"High School of Economics" Saint-PetersburgRussia School of Mathematics and Statistics Qingdao UniversityQingdao266071ShandongChina

This paper is devoted to a new class of differential games with continuous and dynamic *** direct application of resource extraction in a case of dynamic and continuous updating is *** is proved that the optimal control(cooperative strategies)and feedback Nash equilibrium strategies uniformly converge to the corresponding strategies in the game model with continuous updating as the number of updating instants converges to *** results are presented for an optimal trajectory(cooperative trajectory),equilibrium trajectory and corresponding payoffs.

关键词： Differential games Dynamic updating Continuous updating Optimal control Feedback Nash equilibrium