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Belief reliability modeling and analysis for planetary reducer considering multi-source uncertainties and wear

Journal of Systems Engineering and Electronics 2021年第5期32卷 1246-1262页

作者： LI Yun jiang kaige ZENG Ting CHEN Wenbin LI Xiaoyang LI Deyong ZHANG Zhiqiang Beijing Spacecraft Manufacturing Co. LtdChina Academy of Space TechnologyBeijing 100094China School of Reliability and Systems Engineering Beihang UniversityBeijing 100191China Science and Technology on Reliability and Environmental Engineering Laboratory Beijing 100191China

The planetary reducer is a common type of transmission mechanism,which can provide high transmission accuracy and has been widely used,and it is usually required with high reliability of transmission characteristics in *** the manufacturing and usage stages of planetary reducers,uncertainties are ubiquitous and wear is inevitable,which affect the transmission characteristics and the reliability of planetary *** this paper,belief reliability modeling and analysis considering multi-uncertainties and wear are proposed for planetary ***,based on the functional principle and the influence of wear,the performance margin degradation model is established using the hysteresis error as the key performance parameter,where the degradation is mainly caused by the accumulated *** that,multi-source uncertainties are analyzed and quantified separately,including manufacturing errors,uncertainties in operational and environmental conditions,and uncertainties in performance ***,the belief reliability model is established based on the performance margin degradation model.A case study of a planetary reducer is applied and the reliability sensitivity analysis is implemented to show the practicability of the proposed *** results show that the proposed method can provide some suggestions to the design and manufacturing phases of the planetary reducer.

关键词： belief reliability planetary reducer performance margin wear multi-source uncertainty

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HCCDB v2.0:Decompose Expression Variations by Single-cell RNA-seq and Spatial Transcriptomics in HCC

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Genomics, Proteomics & Bioinformatics 2024年第1期22卷 131-142页

作者： Ziming jiang Yanhong Wu Yuxin Miao kaige Deng Fan Yang Shuhuan Xu Yupeng Wang Renke You Lei Zhang Yuhan Fan Wenbo Guo Qiuyu Lian Lei Chen Xuegong Zhang Yongchang Zheng Jin Gu Eight-Year Program of Clinical Medicine Peking Union Medical College HospitalChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100006China MOE Key Laboratory of Bioinformatics BNRIST Bioinformatics DivisionInstitute for Precision Medicine&Department of AutomationTsinghua UniversityBeijing 100084China Department of Liver Surgery Peking Union Medical College HospitalChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100730China Fuzhou Institute for Data Technology Fuzhou 350207China University of Michigan-Shanghai Jiao Tong University Joint Institute Shanghai Jiao Tong UniversityShanghai 200240China Department of Automation Shanghai Jiao Tong UniversityShanghai 200240China International Cooperation Laboratory on Signal Transduction Eastern Hepatobiliary Surgery InstituteSecond Military Medical UniversityShanghai 200438China National Center for Liver Cancer Shanghai 201805China

Large-scale transcriptomic data are crucial for understanding the molecular features of hepatocellular carcinoma(HCC).Integrated 15 transcriptomic datasets of HCC clinical samples,the first version of HCC database(HCCDB v1.0)was released in *** the meta-analysis of differentially expressed genes and prognosis-related genes across multiple datasets,it provides a systematic view of the altered biological processes and the inter-patient heterogeneities of HCC with high reproducibility and *** four years having passed,the database now needs integration of recently published ***,the latest single-cell and spatial transcriptomics have provided a great opportunity to decipher complex gene expression variations at the cellular level with spatial ***,we present HCCDB v2.0,an updated version that combines bulk,single-cell,and spatial transcriptomic data of HCC clinical *** dramatically expands the bulk sample size by adding 1656 new samples from 11 datasets to the existing 3917 samples,thereby enhancing the reliability of transcriptomic meta-analysis.A total of 182,832 cells and 69,352 spatial spots are added to the single-cell and spatial transcriptomics sections,respectively.A novel single-cell level and 2-dimension(sc-2D)metric is proposed as well to summarize cell type-specific and dysregulated gene expression *** are all graphically visualized in our online portal,allowing users to easily retrieve data through a user-friendly interface and navigate between different *** extensive clinical phenotypes and transcriptomic data in the database,we show two applications for identifying prognosis-associated cells and tumor *** v2.0 is available at http://***/database/hccdb2.

关键词： Hepatocellular carcinoma Database Integrative analysis Single-cell RNA sequencing Spatial transcriptomics

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F-CC调和映射的若干结果

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信阳师范学院学报（自然科学版） 2020年第1期33卷 31-36页

作者：冯书香蒋凯歌李静信阳师范学院数学与统计学院河南信阳464000 中山大学数学学院广东广州510275 南京理工大学理学院江苏南京210094

引入从黎曼流形到伪Hermitian流形间的F-CC调和映射的水平能量泛函.利用F-水平应力-能量张量的增长条件和该映射在无穷远点处的渐近条件得到一些刘维尔型结果.

关键词： F-CC调和映射刘维尔型定理 F-水平应力-能量张量

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Hadamard流形中子流形的p-调和函数的刘维尔型定理

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信阳师范学院学报（自然科学版） 2019年第1期32卷 11-16页

作者：韩英波蒋凯歌张倩玉信阳师范学院数学与统计学院河南信阳464000 中山大学数学学院广东广州510275 重庆人文科技学院机电与信息科学学院重庆401524

若Hadamard流形中的完备非紧可定向子流形具有有限全曲率且截面曲率非正,证明了当光滑函数u的Lp范数有限时,任何的p-调和函数一定是一个常数(p≥2).

关键词： p-调和函数刘维尔型定理子流形

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具有势函数的拟-F-调和映射的若干结果

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信阳师范学院学报（自然科学版） 2018年第1期31卷 5-10页

作者：韩英波蒋凯歌张倩玉信阳师范学院数学与统计学院河南信阳464000

引入了从光滑度量测度空间(M,g,e-φ(x)dvg)到黎曼流形中具有势函数的(弱)拟-F-调和映射的概念.在H和Bakry-mery Ricci张量的条件下,利用应力-能量张量证明了上述映射的刘维尔型定理.

关键词：具有势函数的(弱)拟-F-调和映射刘维尔型定理应力-能量张量

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坩埚高径比对泡生大尺寸蓝宝石单晶的影响

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深圳大学学报（理工版） 2016年第6期33卷 599-605页

作者：姜建伟刘凯歌彭小波李玲翟剑庞深圳大学电子科学与技术学院广东深圳518060 深圳大学机电与控制工程学院广东深圳518060 深圳大学光电工程学院广东深圳518060

研究了高径比分别为1.36和1.50的两组坩埚在炉体内的轴向、径向温度梯度和液流情况.在两组坩埚中进行晶体生长实验,将生长出来的晶体进行掏棒和切片,并对晶棒进行应力和气泡检测,对晶片进行位错和双晶摇摆曲线检测.对比理论计算和实验... 详细信息

研究了高径比分别为1.36和1.50的两组坩埚在炉体内的轴向、径向温度梯度和液流情况.在两组坩埚中进行晶体生长实验,将生长出来的晶体进行掏棒和切片,并对晶棒进行应力和气泡检测,对晶片进行位错和双晶摇摆曲线检测.对比理论计算和实验结果表明,当纵横温度变化近似一次函数,且纵横温度梯度作用下的固液面的夹角在45°~60°时,可以有效降低应力,减少开裂几率;当熔体内部只有一个涡旋的时候,可有效减少晶体气泡;坩埚高径比为1.36时,能有效降低位错密度,提高结晶性.

关键词：晶体学蓝宝石晶体泡生法温场模拟发光二极管衬底材料晶体缺陷

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乳酸菌固态发酵过程中麦麸组分的动态变化

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食品与生物技术学报 2024年第2期43卷 30-37页

作者：陈蒙慧江迪关二旗李萌萌刘远晓张凯歌卞科河南工业大学粮油食品学院河南郑州450001

麦麸是小麦加工的主要副产物,营养丰富且产量大,采用乳酸菌处理麦麸可提高其附加值。为明确乳酸菌发酵对麦麸各组分的影响,作者采用植物乳杆菌、鼠李糖乳杆菌、戊糖片球菌和布氏乳杆菌分别对麦麸进行固态发酵,在48 h内每隔8 h取样,分析... 详细信息

麦麸是小麦加工的主要副产物,营养丰富且产量大,采用乳酸菌处理麦麸可提高其附加值。为明确乳酸菌发酵对麦麸各组分的影响,作者采用植物乳杆菌、鼠李糖乳杆菌、戊糖片球菌和布氏乳杆菌分别对麦麸进行固态发酵,在48 h内每隔8 h取样,分析可溶性膳食纤维、粗蛋白质、淀粉、总酚、植酸等成分的质量分数及DPPH自由基清除能力的动态变化。结果表明,在麦麸基质中,4株乳酸菌在24 h内生长较为迅速;麦麸经乳酸菌发酵后可溶性膳食纤维质量分数显著提高,其中布氏乳杆菌发酵48 h后可溶性膳食纤维质量分数由4.72%增加至6.58%;随着发酵时间的增加,麦麸中淀粉质量分数逐渐降低,粗蛋白质量分数先增加后降低最后趋于稳定;植物乳杆菌在提高麦麸多酚质量分数方面有更好的效果,多酚质量分数由1.34 mg/g增加至3.86 mg/g,麦麸抗氧化活性显著增加;此外,乳酸菌发酵麦麸可显著降低其植酸质量分数。综合而言,植物乳杆菌和布氏乳杆菌在提高麦麸的营养特性方面具有较好的效果,可有效改善麦麸的综合利用价值。

关键词：麦麸乳酸菌固态发酵可溶性膳食纤维抗氧化活性

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微生物固态发酵麦麸的营养品质及其资源化利用的研究进展

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食品与发酵工业 2024年第4期50卷 337-346页

作者：张凯歌江迪万小乐关二旗李萌萌陈蒙慧唐浩洁卞科河南工业大学国家粮食和物资储备局粮油食品工程技术研究中心/河南省重点实验室河南郑州450001 河南工业大学粮油食品学院河南郑州450001 大连市检验检测认证技术服务中心辽宁大连116021

麦麸作为小麦加工的主要副产物,年产量超2000万t,其营养丰富,具有很高的应用潜力。但麦麸中存在植酸等抗营养素以及含量较高的不溶性膳食纤维,影响了麦麸生物活性物质的释放,导致其资源化综合利用受到一定限制。因此麦麸的改性处理成为... 详细信息

麦麸作为小麦加工的主要副产物,年产量超2000万t,其营养丰富,具有很高的应用潜力。但麦麸中存在植酸等抗营养素以及含量较高的不溶性膳食纤维,影响了麦麸生物活性物质的释放,导致其资源化综合利用受到一定限制。因此麦麸的改性处理成为研究热点,其中微生物发酵由于其高效、低成本、无污染等特点受到较高的关注。微生物固态发酵能够通过改善麦麸膳食纤维结构、降低抗营养因子水平、促进生物活性物质的释放、提高抗氧化能力来提高麦麸的营养品质和应用价值。该文综述了微生物发酵对麦麸生物活性物质释放、营养品质改善以及在全麦食品品质改善和饲料加工中动物生长性能、肠道健康、免疫调节等方面资源化利用的研究进展,以期为提高麦麸的综合利用率及附加值提供参考。

关键词：微生物固态发酵麦麸营养品质资源化利用

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Experimental Investigation on Compressive Properties of Fiber Recycled Aggregate Concrete

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Journal of Renewable Materials 2023年第11期11卷 3957-3975页

作者： Guiwu Lin kaige Liu Yuliang Chen Yunpeng Ji Rui jiang College of Civil Engineering and Architecture Guangxi University of Science and TechnologyLiuzhou545006China

This paper presents an experimental study to explore the compressive properties of fiber recycled aggregate concrete.A total of 75 specimens with the replacement rate of recycled coarse aggregate and fiber type were conducted under a uniaxial compressive *** failure modes,stress-strain whole curves,peak stress,peak strain,and energy dissipation capacity were systematically observed and *** results indicate that steel fiber has the best modification effect on energy dissipation capacity and the toughness index of recycled concrete,corresponding to the enhancement of 81.75% and 22.90% on *** addition of polyvinyl alcohol fiber can effectively improve the compressive strength and energy dissipation capacity of recycled aggregate concrete by 28.49% and 29.43% on average,*** compressive strength and energy dissipation capacity of recycled aggregate concrete is increased by an average of 16.5% and 24.4% by incorporating carbon *** energy dissipation capacity of recycled aggregate concrete is increased by an average of 13.5% with the incorporation of polypropylene ***,the addition of carbon fiber results in a slight reduction of toughness by 16.97%,and the effect of polyvinyl alcohol fiber on the energy dissipation capacity is ***,with the increase in replacement rate,the compressive strength and the energy dissipation capacity of recycled coarse aggregate concrete with fiber decreased,and toughness first decreased and then ***,based on the analysis of test data,a segment-based stress-strain model of fiber recycled aggregate concrete was proposed,which shows good agreement with the test results.

关键词： Recycled aggregate concrete fiber compressive properties energy dissipation toughness

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Bidirectional differentiation of BMSCs induced by a biomimetic procallus based on a gelatin-reduced graphene oxide reinforced hydrogel for rapid bone regeneration

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Bioactive Materials 2021年第7期6卷 2011-2028页

作者： Delong Jiao Ao Zheng Yang Liu Xiangkai Zhang Xiao Wang Jiannan Wu Wenjun She kaige Lv Lingyan Cao Xinquan jiang Department of Prosthodontics Shanghai Engineering Research Center of Advanced Dental Technology and MaterialsShanghai Key Laboratory of Stomatology&Shanghai Research Institute of StomatologyNational Clinical Research Center for Oral DiseasesShanghai Ninth People’s HospitalCollege of StomatologyShanghai Jiao Tong University School of MedicineChina The State Key Laboratory of Bioreactor Engineering East China University of Science and Technology130 Meilong RoadShanghai 200237China

Developmental engineering strategy needs the biomimetic composites that can integrate the progenitor cells,biomaterial matrices and bioactive signals to mimic the natural bone healing process for faster healing and reconstruction of segmental bone *** prepared the gelatin-reduced graphene oxide(GOG)and constructed the composites that mimicked the procallus by combining the GOG with the photo-crosslinked gelatin *** biological effects of the GOG-reinforced composites could induce the bi-differentiation of bone marrow stromal cells(BMSCs)for rapid bone *** proper ratio of GOG in the composites regulated the composites’mechanical properties to a suitable range for the adhesion and proliferation of ***,the GOG-mediated bidirectional differentiation of BMSCs,including osteogenesis and angiogenesis,could be activated through Erk1/2 and AKT *** methyl vanillate(MV)delivered by GOG also contributed to the bioactive signals of the biomimetic procallus through priming the osteogenesis of *** the repair of the calvarial defect in vivo,the initial hypoxic condition due to GOG in the composites gradually transformed into a well-vasculature robust situation with the bi-differentiation of BMSCs,which mimicked the process of bone healing resulting in the rapid bone *** an inorganic constituent,GOG reinforced the organic photo-crosslinked gelatin hydrogel to form a double-phase biomimetic procallus,which provided the porous extracellular matrix microenvironment and bioactive signals for the bi-directional differentiation of *** show a promised application of the bio-reduced graphene oxide in biomedicine with a developmental engineering strategy.

关键词： Biomimetic procallus Bio-reduced graphene oxide Photo-crosslinked gelatin hydrogel Methyl vanillate Developmental engineering

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