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Analytical model of friction behavior during polymer scratching with conical tip

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Friction 2019年第5期7卷 466-478页

作者： Chengkai jiang han jiang Jianwei ZhanG Guozheng KANG Applied Mechanics and Structure Safety Key Laboratory of Sichuan Province School of Mechanics and Engineering Southwest Jiaotong University

To investigate the effects of the contact geometry, interfacial friction, and substrate recovery on the behavior of polymer scratching using a conical tip, an analytical model is proposed. The normal stress acting on the contact surface between the tip and the substrate is described as a function of the included angle θ, representing the angle between two planes across the axis of the conical tip, and the attack angle β, representing the angle between the conical surface and the substrate material surface. The effects of the rear contact geometry on the scratch friction between the tip and substrate, represented by recovery angle φ, owing to the instantaneous elastic recovery of the polymer substrate, are also introduced. Validated by the experimental and numerical results from the literature, the proposed analytical model can describe well the scratch coefficient of friction(SCOF), which is defined as the ratio of the tangential force to the normal force. Meaningful guidance is provided to understand the scratch friction behavior.

关键词： polymer scratch contact geometry elastic recovery scratch coefficient of friction

Experimental study on the coupling effect of pore-fracture system and permeability controlled by stress in high-rank coal

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Frontiers of Earth Science 2023年第1期17卷 135-144页

作者： jiang han Caifang WU Lu CHENG Key Laboratory of Coalbed Methane Resources and Reservoir Formation(Ministry of Education of China) China University of Mining and TechnologyXuzhou 221116China School of Resources and Geoscience China University of Mining and TechnologyXuzhou 221116China China United Coalbed Methane Corporation Ltd.Beijing 100016China

During the coalbed methane(CBM)exploitation,the reservoir permeability can be affected by the effective stress that varies with the reservoir fluid pressure,which is a complex,dynamic and significant engineering *** analyze the response characteristics of the pore-fracture system by the changing stress,this work simulated reservoir and fluid pressures during the exploitation by adjusting confining pressure and displacement *** sensitivity experiments under different effective stresses were conducted to systematically study the stage variation characteristics of porosity and permeability of *** results show that the permeability decreases exponentially with the increase in effective stress,consistent with previous ***,the porosity shows a V-shaped trend,which is different from the traditional understanding that it would decrease continuously with rising effective *** variation characteristics(of porosity and permeability above)therefore result in a phased porosity sensitivity of coal permeability(PPS).Moreover,the stress sensitivity of the samples was evaluated using the permeability damage rate method(MPDR)and the stress sensitivity coefficient method(MCSS),both of which showed that it ranges from the degree of strong to extremely *** the effective stress is lower than 5–6 MPa,the stress sensitivity of the coal reservoir drops rapidly with effective stress rising;when it is higher than 5–6 MPa,the change in stress sensitivity tends to flatten out,and the stress sensitivity coefficient(CSS)goes down slowly with rising effective ***,suggestions are proposed for the drainage scheme of CBM wells based on the experimental results.

关键词： stress sensitivity porosity sensitivity permeability high-rank coal effective stress

Cutting Force Fluctuation Suppression and Error Homogenization of Noncircular Gear Hobbing Based on the Tool Shifting Method

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Chinese Journal of Mechanical Engineering 2023年第4期36卷 167-179页

作者： Dazhu Li jiang han Xiaoqing Tian Lian Xia Institute of Artificial Intelligence Anhui Polytechnic UniversityWuhu 241000China CIMS Institute Hefei University of TechnologyHefei 230009China

The current research on noncircular hobbing mainly focuses on the linkage model and motion ***,the intermittent cutting characteristics of hobbing would increase uncertainties in the manufacturing *** this paper,a hobbing machining model with tool-shifting characteristics was proposed to solve the problems of cutting force fluctuation and inconsistency of tooth profile envelope accuracy at different positions of the pitch curve in noncircular gear *** on the unit cutting force coefficient method,the undeformed chip volume generated by interrupted cutting was used to characterize the fluctuation trend of the hobbing *** fluctuation characteristics of the cutting force generated by different hobbing models were compared and *** the equivalent gear tooth and hob slotting numbers,an analysis model of the tooth profile envelope error of the noncircular gear was ***,the tooth profile envelope errors at different positions of the pitch curve were compared and analyzed based on the constructed *** transmission structure of the electronic gearbox was constructed based on the proposed hobbing model,and the hobbing experiment was conducted based on the selfdeveloped noncircular gear CNC hobbing *** paper proposes a hobbing method that can effectively suppress the fluctuation of the peak and whole circumference cutting force and reduce the maximum envelope error of the whole circumference gear teeth.

关键词： Noncircular gear Gear hobbing Cutting force Envelope error Machining model

Efficacy and safety of rituximab therapy for systemic lupus erythematosus:a systematic review and meta-analysis

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2012年第9期13卷 731-744页

作者： Lan LAN Fei han jiang-hua CHEN Department of Kidney Disease Center the First Affiliated Hospital School of Medicine Zhejiang University Hangzhou 310003 China

Objective:To review the efficacy and safety of rituximab therapy for systemic lupus erythematosus(SLE).Methods:We searched for randomized controlled trails and observational studies that evaluated the effect of rituximab based on the systemic lupus erythematosus disease activity index(SLEDAI),British Isles lupus assessment group index(BILAG),urine protein levels,and the prednisolone dose,and had adequate data to calculate the mean,standard deviation(SD),and 95% confidence intervals,and to systematically review and meta-analyze observational studies with fixed effects model or random effects ***:We included 2 randomized controlled studies and 19 observational clinical *** summarized the data from the 19 observational studies,analyzed the heterogeneity of the literature,and then used fixed effect model or random effect model for statistical *** SLEDAI,BILAG,and urine protein levels and the prednisolone dosage were decreased after rituximab treatment,and the decreases in the BILAG,urine protein levels,and the prednisolone dose were found to be significant(P<0.05),when compared with baseline ***'s adverse effects generally could be controlled with an effective dosing ***:Although there are still controversies about rituximab's treatment on SLE,but our study had showed that rituximab had favorable effects on refractory *** long-term efficacy and safety of rituximab require further study.

关键词： Systemic lupus erythematosus Rituximab Meta-analysis

Nanocatalytic bacteria disintegration reverses immunosuppression of colorectal cancer

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National Science Review 2022年第11期9卷 208-222页

作者： han jiang Yuedong Guo Zhiguo Yu Ping Hu Jianlin Shi State Key Laboratory of High Performance Ceramics and Superfine Microstructures Shanghai Institute of Ceramics Chinese Academy of SciencesResearch Unit of Nanocatalytic Medicine in Specific Therapy for Serious Disease Chinese Academy of Medical Sciences Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of Sciences Shanghai Tenth People's Hospital Shanghai Frontiers Science Center of Nanocatalytic Medicine School of Medicine Tongji University

Tumor-associated bacteria(TAB) play a critically important role in regulating the microenvironment of a tumor, which consequently greatly deteriorates the therapeutic effects by chemo-and radiotherapy deactivation and, more considerably, leads to substantial immunosuppression. On the contrary, herein we propose a nanocatalytic tumor-immunotherapeutic modality based on the bacteria disintegration by bacteria-specific oxidative damage under magnetic hyperthermia for highly effective immune response activation-promoted tumor regression. A monodispersed and superparamagnetic nanocatalytic medicine modified by arginyl-glycyl-aspartic acid(RGD) and(3-carboxypropyl)triphenylphosphonium bromide(TPP), named as MNP-RGD-TPP herein, has been synthesized, which features selective accumulation at the TAB by the electrostatic affinity, enabling effective TAB disintegration by the nanocatalytic Fenton reaction producing abundant cytotoxic hydroxyl radicals in situ under alternating magnetic field-induced hyperthermia. More importantly, the lipopolysaccharide has been metabolically secreted from the destructed TAB as pathogen-associated molecular patterns(PAMPs) to M1-polarize tumor-associated macrophages(TAMs) and promote the maturation of dendritic cells(DCs) for innate immuno-response activation of TAMs, followed by cytotoxic T lymphocytes awakening under the PAMPs presentation by the mature DCs against tumor cells. The integrated innate and adaptive immunity activations based on this TAB-promoted nanocatalytic immunomedicine, instead of magnetic heating-induced hyperthermia or the released Fe2+/Fe3+Fenton agent, has been found to achieve excellent therapeutic efficacy in an orthotopic colorectal cancer model, demonstrating the great potential of such an integrated immunity strategy in clinical tumor immunotherapy.

关键词： tumor-associated bacteria nanocatalytic bacteria disintegration immunosuppressive reversal colorectal cancer immunotherapy

Dynamic Modeling and Analysis ofWind Turbine Blade of Piezoelectric Plate Shell

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Sound & Vibration 2019年第1期53卷 14-24页

作者： Yinhu Qiao Chunyan Zhang jiang han School of Mechanical Engineering College Anhui Science and Technology UniversityFengyang233100China School of Mechanical Engineering Hefei University of TechnologyHefei230000China

This paper presents a theoretical analysis of vibration control technology of wind turbine blades made of piezoelectric intelligent *** design of the blade structure,which is made from piezoelectric material,is approximately equivalent to a flat shell *** differential equations of piezoelectric shallow shells for vibration control are derived based on piezoelectric laminated shell *** this basis,wind turbine blades are simplified as elastic piezoelectric laminated *** establish the electromechanical coupling system dynamic model of intelligent structures and the dynamic equation of composite piezoelectric flat shell structures by analyzing simulations of active vibration *** results show that,under wind load,blade vibration is reduced upon applying the control voltage.

关键词： Wind-turbine blade smart structure laminated shallow shell dynamics modeling

Decoratable hybrid-film-patch stabilized Pickering emulsions and their catalytic applications

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Nano Research 2015年第8期8卷 2603-2610页

作者： Shenghua Ma Yinan Wang Kunpeng jiang Xiaojun han State Key Laboratory of Urban Water Resource and Environment School of Chemical Engineering and Technology Harbin Institute ofTechnology Harbin 150001 China

We demonstrated a method to fabricate functional hybrid film patches that were used to form Pickering emulsions （PEs）. The hybrid patches were made of carbon nanotubes, Fe3O4 nanoparticles, octadecyltrimethoxysilane, and poly（diallyldimethylammonium chloride）. The aqueous phase of the hybridpatch stabilized PEs can be easily separated by applying a magnetic field. The hybrid-film-patch stabilized PEs are extremely stable and lasted for eight months at room temperature. Furthermore, they are easily ruptured by adding ethanol, and regenerated by vortexing the patches in aqueous/oil mixtures, enabling the inner hydrophilic side of the patches to be easily modified with metal nanoparticles. As an example, palladium nanoparticles were embedded into the surface of the hybrid patches using an in situ reduction method. The Pd functionalized patch formed PEs showed an excellent catalytic performance for the hydrogenation of acetone with a yield of 99.5%. The same batch of Pd functionalized patches was recycled 13 times without loss of the catalytic activity. The hybrid-patch formed PEs have a great potential in the catalytic field.

关键词： Pickering emulsion hybrid film patches catalysis carbon nanotubes Fe3O4 nanoparticles

High-Speed and Low-Noise Gear Finishing by Gear Grinding and Honing:A Review

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Chinese Journal of Mechanical Engineering 2024年第5期37卷 19-39页

作者： Xiaoqing Tian Yukai Sun Weihao Mu Lian Xia jiang han School of Mechanical Engineering Hefei University of TechnologyHefei 230009China

Gears are important mechanical parts for transmitting power and play an increasingly important role in the machinery *** electric vehicle industry developed rapidly and became a vital development field of the automotive industry over the past few *** conversion of energy increases the requirements for electric vehicle transmissions,which promotes the development of high-speed and low-noise transmission *** paper elaborates on the research progress of high-speed and low-noise gear finishing ***,this review analyses the machining requirements,finishing,and specific machining technologies of high-speed and low-noise *** importance of gear grinding and honing in high-speed and low-noise gear machining is ***,the applications of gear grinding and honing in gear modification,error compensation,and texture control are ***,the role of precision machining technology in improving gear performance is ***,the design and processing methods of the modified tooth flank for gear modification are *** addition,the influence of tooth surface texture on noise is described,and the texture change methods are *** well-known open problems of gear finishing are finally identified,and some new research interests are also pointed *** review will provide valuable references for further research on gear finishing.

关键词： High-speed and low-noise gear Gear machining technology Gear finishing Tooth flank modification Tooth surface texture

g-C_(3)N_(4)/TiO_(2-X) heterojunction with high-efficiency carrier separation and multiple charge transfer paths for ultrasensitive SERS sensing

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Chinese Chemical Letters 2024年第10期35卷 524-529页

作者： Xin jiang han jiang Yimin Tang Huizhu Zhang Libin Yang Xiuwen Wang Bing Zhao College of Chemistry and Chemical Engineering Technology Innovation Center of Industrial Hemp for State Market RegulationQiqihar UniversityQiqihar 161006China College of Pharmacy Jjiamusi UniversityJjiamusi 154007China State Key Laboratory of Supramolecular Structure and Materials Jilin UniversityChangchun 130012China

The combination of interface engineering and defect engineering is a promising strategy for developing new semiconducting surface-enhanced Raman scattering(SERS)***,an organic/inorganic hybrid g-C_(3)N_(4)/TiO_(2-X)heterojunction with synchronous generation of strong interface effect and abundan surface oxygen vacancy(OV)defect was prepared by a simple sol-hydrothermal procedure with a help of *** to the improved substrate-to-molecule charge transfer(CT)from joint contribution of high efficiency carrier separation induced by strong interface coupling effect and multiple CT paths derived from abundant surface OV,g-C_(3)N_(4)/TiO_(2-X)substrate exhibits greatly enhanced SERS effect for non-resonan4-mercaptobenzoic acid(4-MBA)*** enhancement factor of g-C_(3)N_(4)/TiO_(2-X)substrate for 4-MBA i as high as 5.57×10^(6),and the substrate exhibits ultra-high stability and excellent spectral reproducibility More meaningfully,the developed g-C_(3)N_(4)/TiO_(2-X)heterojunction can be used to execute an ultrasensitive detection for antibiotic residues in real water system,even comprehensive evaluation of multi-componen residues.

关键词： SERS Semiconductor Heterojunction Surfacedefect Detection