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Do nocturnal birds use acoustic and visual cues to avoid predation by bats?

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Integrative Zoology 2024年第3期19卷 524-537页

作者： Lixin GONG huan WU Zhiqiang WANG Hui WU jiang feng Tinglei jiang Jilin Provincial Key Laboratory of Animal Resource Conservation and Utilization Northeast Normal UniversityChangchunChina Key Laboratory of Vegetation Ecology of Education Ministry Institute of Grassland ScienceNortheast Normal UniversityChangchunChina College of Life Science Jilin Agricultural UniversityChangchunChina

Anti-predation strategies are critical to animal survival and are fundamental to deciphering predator–prey *** an important defense strategy,sensory predator detection(such as through acoustic and visual cues)enables animals to assess predation risk and execute predator-avoidance behavior;however,there are limited studies on the anti-predation behavior of nocturnal *** prey of bats provides an excellent representative system for examining the anti-predation behavior of nocturnal ***,we broadcasted different types of echolocation calls of the bird-eating bat Ia io to two wild passerine birds,namely,Zosterops japonicus and Sinosuthora webbiana,that are preyed upon by ***,and presented the birds with individual bats under different light *** results showed that both bird species were able to perceive the low-frequency audible portion of the bats’echolocation calls;however,they did not exhibit escape responses to the acoustic *** the dark and under moonlit conditions,both bird species were unable to respond to active bats at close range and the birds only exhibited evasive flight behavior when bats approached or touched *** results suggest that nocturnal passerine birds may not be able to use acoustic or visual cues to detect bats and adopt evasive maneuvers to avoid *** work suggests that bat predation pressure may not elicit primary predator-avoidance responses in nocturnal passerine *** results provide new insights into the anti-predation behavior of nocturnal animals.

关键词： anti-predation behavior nocturnal animals sensory cues sensory defenses

高速列车牵引传动系统综合仿真平台的分析与设计

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铁道学报 2012年第2期34卷 21-26页

作者：冯江华王坚李江红南车株洲电力机车研究所有限公司湖南株洲412001

本文介绍CRH2型高速列车牵引传动系统结构和工作原理,对基于多学科协同仿真的高速列车综合仿真平台进行分析和研究。利用支持UML的Rational Rose工具进行完整的系统需求分析,介绍仿真平台的组成及各部分功能,提出基于HLA-RTI和反射内存... 详细信息

本文介绍CRH2型高速列车牵引传动系统结构和工作原理,对基于多学科协同仿真的高速列车综合仿真平台进行分析和研究。利用支持UML的Rational Rose工具进行完整的系统需求分析,介绍仿真平台的组成及各部分功能,提出基于HLA-RTI和反射内存网的混合网络系统架构,并基于该平台对CRH2型高速列车进行综合仿真试验,验证仿真平台的有效性。

关键词：高速列车仿真 HLA-RTI 反射内存网

Efficient ammonia electrosynthesis from nitrate via a three-step relay mechanism

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Science China Chemistry 2024年第1期67卷 319-320页

作者： Haifeng jiang Gao-feng Chen Haihui Wang Beijing Key Laboratory for Membrane Materials and Engineering Department of Chemical EngineeringTsinghua UniversityBeijing 100084China Department of Colloid Chemistry Max-Planck Institute of Colloids and InterfacesPotsdam 14476Germany School of Chemistry and Chemical Engineering South China University of TechnologyGuangzhou 510640China

Electrocatalytically converting nitrate waste to value-added ammonia(NO3−RR)is beneficial to environmental restoration and an attractive candidate for green ammonia production[1].However,developing NO_(3)^(-)RR in an energy-saving way remains a significant challenge due to the slow kinetics inherent in multi-step electron and proton transfer,making previous investigations for NO_(3)^(-)RR generally operate at a large overpotential(<-0.2 V versus reversible hydrogen electrode(RHE))to achieve optimal efficiency and industrial current for NH3 synthesis[2].

关键词： ammonia nitrate kinetics

Emerging role of exosomes in ulcerative colitis: Targeting NOD-like receptor family pyrin domain containing 3 inflammasome

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World Journal of Gastroenterology 2024年第6期30卷 527-541页

作者： Xin Li Li-jiang Ji Kai-Di feng hua huang Mei-Rou Liang Shi-Jin Cheng Xiu-Dong Meng School of Basic Medicine Guizhou University of Traditional Chinese MedicineGuiyang 550025Guizhou ProvinceChina Department of Anorectal Surgery Changshu Hospital Affiliated to Nanjing University of Chinese MedicineChangshu 215500Jiangsu ProvinceChina College of Traditional Chinese Medicine Tianjin University of Traditional Chinese MedicineTianjin 301617China

Ulcerative colitis(UC)is a chronic recurrent inflammatory bowel *** ongoing advances in our understanding of UC,its pathogenesis is yet unelu-cidated,underscoring the urgent need for novel treatment strategies for patients with *** are nanoscale membrane particles that mediate intercellular communication by carrying various bioactive molecules,such as proteins,RNAs,DNA,and *** NOD-like receptor family pyrin domain containing 3(NLRP3)inflammasome is a cytosolic tripartite protein complex whose activation induces the maturation and secretion of proinflammatory cytokines interleukin-1β(IL-1β)and IL-18,triggering the inflammatory response to a pathogenic agent or *** evidence suggests that exosomes are new modulators of the NLRP3 inflammasome,with vital roles in the pathological process of ***,recent evidence is reviewed on the role of exosomes and NLRP3 inflammasome in ***,the dual role of exosomes on NLRP3 inflammasome and the effect of NLRP3 inflammasome on exosome secretion are ***,an outlook on the directions of exosome-NLRP3 inflammasome crosstalk research in the context of UC is proposed and areas of further research on this topic are high-lighted.

关键词： Ulcerative colitis Exosomes Inflammasome Evidence Therapeutics

Counteracting effects on ENSO induced by ocean chlorophyll interannual variability and tropical instability wave-scale perturbations in the tropical Pacific

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Science China Earth Sciences 2024年第2期67卷 387-404页

作者： Rong-hua ZHANG feng TIAN Qidong SHI Xiujun WANG Tongwen WU School of Marine Sciences Nanjing University of Information Science and TechnologyNanjing210044China Laoshan Laboratory Qingdao266237China Key Laboratory of Ocean Circulation and Waves Institute of OceanologyChinese Academy of SciencesQingdao266071China University of Chinese Academy of Sciences Beijing101408China Faculty of Geographical Sciences Beijing Normal UniversityBeijing100875China Earth System Modeling and Prediction Centre China Meteorological AdministrationBeijing100081China

Large perturbations in chlorophyll(Chl)are observed to coexist at interannual and tropical instability wave(TIW)scales in the tropical Pacific;at present,their combined effects on El Ni?o-Southern Oscillation(ENSO)through ocean biologyinduced heating(OBH)feedbacks are not understood ***,a hybrid coupled model(HCM)for the atmosphere and ocean physics-biogeochemistry(AOPB)in the tropical Pacific is adopted to quantify how ENSO can be modulated by Chl perturbations at interannual and TIW scales,individually or collectively,*** HCM-based sensitivity experiments demonstrate a counteracting effect on ENSO:the bio-climate feedback due to large-scale Chl interannual variability acts to damp ENSO through its impact on upper-ocean stratification and vertical mixing,whereas that due to TIW-scale Chl perturbations tends to amplify *** ENSO simulations are sensitively dependent on the ways Chl effects are represented at these different scales,it is necessary to adequately take into account these related differential Chl effects in climate modeling.A bias source for ENSO simulations is illustrated that is related with the Chl effects in the tropical Pacific,adding in a new insight into interactions between the climate system and ocean ecosystem on different scales in the *** results reveal a level of complexity of ENSO modulations resulting from Chl effects at interannual and TIW scales,which are associated with ocean biogeochemical processes and their interactions with physical processes in the tropical Pacific.

关键词： Ocean chlorophyll Bio-climate feedbacks Interannual variability Tropical instability waves Counteracting effects A hybrid coupled model

Microneedle patch loaded with ferritin-nanocaged doxorubicin for locally targeted drug delivery and efficient skin cancer treatment

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Particuology 2024年第5期88卷 282-289页

作者： feng Li Yuan Yang hua Yue Shuang Wang Xiao Zhang Wei Wei State Key Laboratory of Biochemical Engineering Institute of Process EngineeringChinese Academy of SciencesBeijing100190China Key Laboratory of Biopharmaceutical Preparation and Delivery Chinese Academy of SciencesBeijing100190China School of Chemical Engineering University of Chinese Academy of SciencesBeijing100049China

Ferritin has emerged as a promising nanocarrier for delivering therapeutic agents to ***,the limited drug loading and the off-target impacts after systemic administration remain challenges for cancer treatment with ferritin-based ***,we develop a microneedle patch loaded with ferritin-nanocaged doxorubicin(DoxFe@Fn/MN)for skin cancer ***,doxorubicin(Dox)is encapsulated in ferritin(Fn)using an iron core-assisted strategy,which results in a 3.4-fold increase in Dox loading compared to the direct loading ***,a polyvinyl alcohol-based microneedle(MN)patch is used for the transdermal delivery of DoxFe@Fn,enabling targeted tumour accumulation of DoxFe@Fn and preventing off-target *** released DoxFe@Fn can bind to CD71 highly expressed on skin cancer cells,facilitating its *** a result,the DoxFe@Fn/MN therapy presents a robust antitumour effect in a melanoma tumour model,showing its potential as a promising therapeutic modality for skin cancer treatment.

关键词： Ferritin Microneedle Skin cancer Drug delivery

Cisplatin-based miRNA delivery strategy inspired by the circCPNE1/miR-330-3p pathway for oral squamous cell carcinoma

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Acta Pharmaceutica Sinica B 2024年第6期14卷 2748-2760页

作者： hua-yang Fan Ming-da Zhao Hong-jie jiang Zhen-wei Yu Yu-jiang Fan Xin-hua Liang Ya-ling Tang Yong Sun State Key Laboratory of Oral Diseases&National Center for Stomatology&National Clinical Research Center for Oral Diseases&Department of Oral and Maxillofacial Surgery West China Hospital of StomatologySichuan UniversityChengdu 610041China National Engineering Research Center for Biomaterials Sichuan UniversityChengdu 610065China State Key Laboratory of Oral Diseases&National Center for Stomatology&National Clinical Research Center for Oral Diseases&Department of Oral Pathology West China Hospital of StomatologySichuan UniversityChengdu 610041China

Circular RNAs(circRNAs)are ideal biomarkers of oral squamous cell carcinoma(OSCC)because of their highly stable closed-loop structure,and they can act as microRNA(miRNA)sponges to regulate OSCC *** analyzing clinical samples,we identified circCPNE1,a dysregulated circRNA in OSCC,and its expression level was negatively correlated with the clinical stage of OSCC ***-of-function assays revealed the tumor-suppressive effect of circCPNE1,which was then identified as a miR-330-3p ***-330-3p was recognized as a tumor promoter in multiple studies,consistent with our finding that it could promote the proliferation,migration,and invasion of OSCC *** results indicated that selective inhibition of miR-330-3p could be an effective strategy to inhibit OSCC ***,we designed cationic polylysine-cisplatin prodrugs to deliver antagomiR-330-3p(a miRNA inhibitory analog)via electrostatic interactions to form PP@miR nanoparticles(NPs).Paratumoral administration results revealed that PP@miR NPs effectively inhibited subcutaneous tumor progression and achieved partial tumor elimination(2/5),which confirmed the critical role of miR-330-3p in OSCC *** findings provide a new perspective for the development of OSCC treatments.

关键词： Oral squamous cell carcinoma CircRNA MiRNA sponge Antagomir MiRNA delivery Cisplatin-based nanoparticles Drug delivery systems Tumor elimination

蜂窝夹层板动力分析的Hamilton体系与辛算法

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航空学报 2006年第2期27卷 236-240页

作者：罗恩黄伟江姜凤华中山大学应用力学与工程系广东广州510275 广州市建筑科学研究院广东广州510440

将蜂窝夹层板动力分析从Lagrange体系改换为Hamilton体系。通过作者早已提出的一条简单而统一的新途径,建立了蜂窝夹层板动力学的相空间非传统Hamilton变分原理,并从该原理推导出相应的Ham-ilton正则方程、边界条件与初始条件。然后基... 详细信息

将蜂窝夹层板动力分析从Lagrange体系改换为Hamilton体系。通过作者早已提出的一条简单而统一的新途径,建立了蜂窝夹层板动力学的相空间非传统Hamilton变分原理,并从该原理推导出相应的Ham-ilton正则方程、边界条件与初始条件。然后基于这种相空间非传统Hamilton变分原理,提出蜂窝夹层板动力响应分析的辛空间有限元-时间子域法,算例的数值结果表明,这种新方法的计算精度与效率都明显高于国际上常用的Wilson-θ法和Newmark-β法。

关键词：蜂窝夹层板 Hamilton体系相空间非传统Hamilton变分原理动力响应分析辛空间有限元-时间子域法

Extrusion 3D printing of carbon nanotube-assembled carbon aerogel nanocomposites with high electrical conductivity

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Nano Materials Science 2024年第3期6卷 312-319页

作者： Lukai Wang Jing Men Junzong feng Yonggang jiang Liangjun Li Yijie Hu Jian feng Science and Technology on Advanced Ceramic Fibers and Composites Laboratory College of Aerospace Science and EngineeringNational University of Defense Technology109 De Ya RdChangshaHunan410073PR China

Carbon nanotubes(CNTs)with high aspect ratio and excellent electrical conduction offer huge functional improvements for current carbon ***,there remains a major challenge for achieving the on-demand shaping of carbon aerogels with tailored micro-nano structural textures and geometric ***,a facile extrusion 3D printing strategy has been proposed for fabricating CNT-assembled carbon(CNT/C)aerogel nanocomposites through the extrusion printing of pseudoplastic carbomer-based inks,in which the stable dispersion of CNT nanofibers has been achieved relying on the high viscosity of carbomer *** extrusion printing,the chemical solidification through polymerizing RF sols enables 3D-printed aerogel nanocomposites to display high shape fidelity in macroscopic *** from the micro-nano scale assembly of CNT nanofiber networks and carbon nanoparticle networks in composite phases,3D-printed CNT/C aerogels exhibit enhanced mechanical strength(fracture strength,0.79 MPa)and typical porous structure characteristics,including low density(0.220 g cm^(-3)),high surface area(298.4 m^(2)g^(-1)),and concentrated pore diameter distribution(~32.8nm).More importantly,CNT nanofibers provide an efficient electron transport pathway,imparting 3D-printed CNT/C aerogel composites with a high electrical conductivity of 1.49 S cm^(-1).Our work would offer feasible guidelines for the design and fabrication of shape-dominated functional materials by additive manufacturing.

关键词： Carbon aerogel Extrusion 3D printing Carbon nanotube Electrical conductivity Rheology