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Enhanced flow injection analysis for measurements of S-nitrosothiols species in biological samples using highly selective amperometric nitric oxide sensor

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Chinese Chemical Letters 2012年第2期23卷 229-232页

作者： chun Cui Huang Hui bo Shao Key Laboratory of Cluster Science Ministry of Education of ChinaSchool of ChemistryBeijing Institute of TechnologyBeijing 100081China

A highly selective nitric oxide（NO） sensor is fabricated and applied to devise an enhanced flow injection analysis（FIA） system for S-nitrosothiols（RSNOs） measurement in biological *** NO sensor is prepared using a polytetrafluoroethylene（PTFE） gas-permeable membrane loaded with Teflon AF？ solution,a copolymer of tetrafluoroethylene and 2,2-bis（trifluoroethylene）-4,5-difluoro -l,3-dioxole,to improve *** method is much simpler and possesses good performance over a wide range of RSNOs *** deviation for three parallel measurements of blood plasma is 4.0%.The use of the gas sensing configuration as the detector enhances selectivity of the FIA measurement *** less selective electrochemical detectors that do not use PTFE/Teflon type outer membranes.

关键词： Enhanced FIA method Plasma RSNOs Highly selective NO sensor

In situ prepared Al-Si alloy matrix composites reinforced by γ-Al_2O_3p

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Journal of University of Science and Technology Beijing 2007年第3期14卷 276-279页

作者： Lan jiang bo jiang Zhaofei Wang Yue Wang Ji Liu School of Materials and Metallurgy Northeastern University Shenyang 110004 China School of Environmental and Biological Science ＆ Technology Dalian University of Technology Dalian 116024 China

A γ-Al2O3 particles reinforced Al-Si alloy matrix composite was fabricated by adding NH4Al（SO4）2 to molten aluminum alloy. TEM observation shows that in-situ γ-Al2O3 particles are generally spherical and uniformly distributed in the matrix. The results of dry sliding wear tests show that the wear resistance of the composites increases with increasing mass fraction, and the volume loss is considerably lesser than that of the matrix and is lesser than that of the composites by adding γ-Al2O3 particles directly.

关键词： aluminum matrix composite in-situ γ-Al2O3 particles microstructure wear behavior

The surge-like eruption of a miniature filament

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Research in Astronomy and Astrophysics 2012年第3期12卷 300-312页

作者： Jia-Yan Yang Yun-chun jiang Dan Yang Yi Bi bo Yang Rui-Sheng Zheng Jun-Chao Hong National Astronomical Observatories / Yunnan Observatory Chinese Academy of Sciences Kunming 650011 China Key Lab-oratory for the Structure and Evolution of Celestial Objects Chinese Academy of Sciences Kunming 650011 China Graduate University of Chinese Academy of Sciences Beijing 100049 China

We report on the rare eruption of a miniature Hα filament that took the form of a surge. The filament first underwent a full development within 46 min and then began to erupt 9 min later, followed by a compact, impulsive X-ray class M2.2 flare with a two-ribbon nature only at the early eruption phase. During the eruption, its top rose, whereas the two legs remained rooted in the chromosphere and showed little swelling perpendicular to the rising direction. This led to a surge-like eruption with a narrow angular extent. Similar to the recent observations for standard and blowout X- ray jets by Moore et al., we thus define it as a ＂blowout Hα surge.＂ Furthermore, our observations showed that the eruption was associated with （1） a coronal mass ejection guided by a pre-existing streamer, （2） abrupt, significant, and persistent changes in the photospheric magnetic field around the filament, and （3） a sudden disappearance of a small pore. These observations thus provide evidence that a blowout surge is a small- scale version of a large-scale filament eruption in many aspects. Our observations further suggest that at least part of the Hα surges belong to blowout-type cases, and the exact distinction between the standard and blowout Hα surges is important in understanding their different origins and associated eruptive phenomena.

关键词： Sun: activity—Sun: filaments—Sun: flares—Sun: magnetic field—Sun: coronal mass ejections (CMEs)

Exploring the Feasibility of Machine Learning to Predict Risk Stratification Within 3 Months in Chest Pain Patients with Suspected NSTE-ACS

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Biomedical and Environmental Sciences 2023年第7期36卷 625-634页

作者： ZHENG Zhi Chang YUAN Wei WANG Nian jiang bo MA chun Peng AI Hui WANG Xiao NIE Shao Ping Cardiovascular Medicine Department Beijing Bo’ai HospitalChina Rehabilitation Research CenterCapital Medical UniversityBeijing 100068China Center for Coronary Artery Disease Beijing Anzhen HospitalCapital Medical UniversityBeijing 100029China Respiratory Medicine Department Beijing Friendship Hospital Affiliated of Capital Medical UniversityBeijing 100050China School of Computer Science and Engineering Beihang UniversityBeijing 100191China Department of Cardiology the First Hospital of QinhuangdaoHebei Medical UniversityQinhuangdao 066001HebeiChina

Objective We aimed to assess the feasibility and superiority of machine learning(ML)methods to predict the risk of Major Adverse Cardiovascular Events(MACEs)in chest pain patients with *** Enrolled chest pain patients were from two centers,Beijing Anzhen Emergency Chest Pain Center Beijing bo’ai Hospital,China Rehabilitation Research *** classifiers were used to develop ML ***,Precision,Recall,F-Measure and AUC were used to assess the model performance and prediction effect compared with HEART risk scoring ***,ML model constructed by Naïve Bayes was employed to predict the occurrence of *** According to learning metrics,ML models constructed by different classifiers were superior over HEART(History,ECG,Age,Risk factors,&Troponin)scoring system when predicting acute myocardial infarction(AMI)and all-cause ***,according to ROC curves and AUC,ML model constructed by different classifiers performed better than HEART scoring system only in prediction for *** the five ML algorithms,Linear support vector machine(SVC),Naïve Bayes and Logistic regression classifiers stood out with all Accuracy,Precision,Recall and F-Measure from 0.8 to 1.0 for predicting any event,AMI,revascularization and all-cause death(***≤0.78),with AUC from 0.88 to 0.98 for predicting any event,AMI and revascularization(***≤0.85).ML model developed by Naïve Bayes predicted that suspected acute coronary syndrome(ACS),abnormal electrocardiogram(ECG),elevated hs-cTn I,sex and smoking were risk factors of *** Compared with HEART risk scoring system,the superiority of ML method was demonstrated when employing Linear SVC classifier,Naïve Bayes and *** method could be a promising method to predict MACEs in chest pain patients with NSTE-ACS.

关键词： Machine learning MACEs Chest pain Suspected NSTE-ACS

Comparative analysis of DNA-SIP and magnetic-nanoparticle mediated isolation (MMI) on unraveling dimethoate degraders

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Frontiers of Environmental Science & Engineering 2024年第1期18卷 59-69页

作者： Luning Lian Yi Xing Dayi Zhang Longfei jiang Mengke Song bo jiang School of Energy and Environmental Engineering University of Science&Technology BeijingBeijing 100083China Beijing Key Laboratory of Resource-oriented Treatment of Industrial Pollutants University of Science&Technology BeijingBeijing 100083China National Environmental and Energy Science and Technology International Cooperation Base University of Science&Technology BeijingBeijing 100083China College of New Energy and Environment Jilin UniversityChangchun 130021China Guangzhou Institute of Geochemistry Chinese Academy of SciencesGuangzhou 510640China College of Natural Resources and Environment South China Agricultural UniversityGuangzhou 510642China National Engineering Laboratory for Site Remediation Technologies Beijing 100015China

Microorganisms are crucial in the bioremediation of organophosphorus pesticides. However, most functional microorganisms (> 99%) are yet to be cultivated. This study applied two cultivation-independent approaches, DNA-SIP and magnetic-nanoparticle mediated isolation (MMI), to identify the functional microorganisms in degrading dimethoate in agricultural soils. MMI identified five dimethoate degraders: Pseudomonas, Bacillus, Ramlibacter, Arthrobacter, and Rhodococcus, whereas DNA-SIP identified three dimethoate degraders: Ramlibacter, Arthrobacter, and Rhodococcus. Also, MMI showed higher resolution than DNA-SIP in identifying functional microorganisms. Two organic phosphohydrolase (OPH) genes: ophC2 and ophB, were involved in dimethoate metabolism, as revealed by DNA-SIP and MMI. The degradation products of dimethoate include omethoate, O,O,S-trimethyl thiophosphorothioate, N-methyl-2-sulfanylacetamide, O,O-diethyl S-hydrogen phosphorodithioate, O,O,O-trimethyl thiophosphate, O,O,S-trimethyl thiophosphorodithioate, and O,O,O-trimethyl phosphoric. This study emphasizes the feasibility of using SIP and MMI to explore the functional dimethoate degraders, expanding our knowledge of microbial resources with cultivation-independent approaches.

关键词： Stable isotope probing(SIP) Magnetic-nanoparticle mediated isolation(MMI) Dimethoate Biodegradation Cultivation-independent approach

Complete Hypersurfaces with Constant Laguerre Scalar Curvature in R^n

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Acta Mathematica Sinica,English Series 2016年第6期32卷 715-724页

作者： Jian bo FANG Feng jiang LI School of Mathematics and Statistics Chuxiong Normal University Department of Mathematics Yunnan Normal University

Let x ： M^n-1→ R^n be an umbilical free hypersurface with non-zero principal curvatures. Two basic invariants of M under the Laguerre transformation group of Rn are Laguerre form C and Laguerre tensor L. In this paper, we prove the following theorem： Let M be an （n-1）-dimensional （n 〉 3） complete hypersurface with vanishing Laguerre form and with constant Laguerre scalar curvature R in R^n, denote the trace-free Laguerre tensor by L = L -1/n-1tr（L）· Id. If supM ｜｜L｜｜=0,then M is Laguerre equivalent to a Laguerre isotropic hypersurface; and if supM ｜｜L^-｜｜≡√（n-1）（n-2）R/ （n-1）（n-2）（n-3） , M isLaguerre equivalent to the hypersurface x^- ： H^1× S^n-2 → R^n.

关键词： Laguerre isoparametric hypersurface Laguerre second fundamental form Laguerre metric Laguerre form parallel Laguerre form

Some Developments in Nielsen Fixed Point Theory

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Acta Mathematica Sinica,English Series 2018年第1期34卷 91-102页

作者： bo Ju jiang Xue Zhi ZHAO School of Mathematical Sciences Peking University Department of Mathematics Capital Normal University

We give a brief survey of some developments in Nielsen fixed point theory. After a look at early history and a digress to various generalizations, we confine ourselves to several topics on fixed points of self-maps on manifolds and polyhedra. Special attention is paid to connections with geometric group theory and dynamics, as well as some formal approaches.

关键词： Fixed points Nielsen theory

Know Thy Enemy:Untangling the Mysteries of Neuropathic Pain

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Neuroscience Bulletin 2021年第11期37卷 1639-1641页

作者： Mahar Fatima Chia chun Hor bo Duan Department of Molecular Cellularand Developmental BiologyUniversity of MichiganAnn ArborMI48109USA

Acute pain plays an important physiological role as a warning system for the ***,in many patients,nerve danlage leads to neuropathic pain that can last for years and disrupts their quality of ***.

关键词： Acute pain patients

An Accelerated Stochastic Mirror Descent Method

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Journal of the Operations Research Society of China 2024年第3期12卷 549-571页

作者： bo-Ou jiang Ya-Xiang Yuan LSEC ICMSECAMSSChinese Academy of SciencesBeijing100190China Department of Mathematics University of Chinese Academy of SciencesBeijing100049China

Driven by large-scale optimization problems arising from machine learning,the development of stochastic optimization methods has witnessed a huge *** types of methods have been developed based on vanilla stochastic gradient descent ***,for most algorithms,convergence rate in stochastic setting cannot simply match that in deterministic *** understanding the gap between deterministic and stochastic optimization is the main goal of this ***,we are interested in Nesterov acceleration of gradient-based *** our study,we focus on acceleration of stochastic mirror descent method with implicit regularization *** that the problem objective is smooth and convex or strongly convex,our analysis prescribes the method parameters which ensure fast convergence of the estimation error and satisfied numerical performance.

关键词： Large-scale optimization Variance reduction Mirror descent Acceleration Independent sampling Importance sampling