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Human-Machine Shared Lateral Control Strategy for Intelligent Vehicles Based on Human Driver Risk Perception Reliability

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Automotive Innovation 2024年第1期7卷 102-120页

作者： Dongjian Song Bing Zhu jian zhao Jiayi Han State Key Laboratory of Automotive Simulation and Control Jilin UniversityChangchun 130022China

Intelligent vehicle(Ⅳ)technology has developed rapidly in recent ***,achieving fully unmanned driving still presents numerous challenges,which means that human drivers will continue to play a vital role in vehicle operation for the foreseeable ***-machine shared driving,involving cooperation between a human driver and an automated driving system(AVS),has been widely regarded as a necessary stage for the development of *** onⅣdriving safety,this study proposed a human-machine shared lateral control strategy(HSLCS)based on the reliability of driver risk *** HSLCS starts by identifying the effective areas of driver risk perception based on eye *** establishes an anisotropic driving risk field,which serves as the foundation for the AVS to assess risk *** upon the cumulative and diminishing effects of risk perception,the proposed approach leverages the driver's risk perception effective area and converts the risk field into a representation aligned with the driver's ***,it quantifies the reliability of the driver's risk perception by using area-matching ***,based on the driver’s risk perception reliability and dif-ferences in lateral driving operation between the human driver and the AVS,the dynamic distribution of driving authority is achieved through a fuzzy rule-based system,and the human-machine shared lateral control is completed by using model predictive *** HSLCS was tested across various scenarios on a driver-in-the-loop test *** results show that the HSLCS can realize the synergy and complementarity of human and machine intelligence,effectively ensuring the safety ofⅣoperation.

关键词： Intelligent vehicle Human-machine shared driving Risk perception Driving authority distribution

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An aptamer-driven DNA nanodevice for improved delivery of synthetic immunostimulants

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Nano Research 2024年第10期17卷 9078-9083页

作者： Dejie Lu Zhenghan Di Lele Li jian zhao Li Zheng Guangxi Engineering Center in Biomedical Materials for Tissue and Organ Regeneration Collaborative Innovation Centre of Regenerative Medicine and Medical BioResource Development and ApplicationGuangxi Key Laboratory of Regenerative MedicineThe First Affiliated Hospital of Guangxi Medical UniversityGuangxi Medical UniversityNanning 530021China CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety National Center for Nanoscience and TechnologyBeijing 100190China

Efficient delivery of therapeutics to immune cells remains a formidable challenge for cancer *** this work,we demonstrate that an aptamer-driven DNA nanodevice,constructed through linkage of a synthetic immunostimulant(Toll-like receptor 9 agonist:CpG motif)to an aptamer,could significantly enhance the immunostimulatory activity by facilitating the uptake and retention of therapeutics in *** administration of the DNA nanodevice results in efficient tumor growth inhibition in both breast cancer and melanoma mouse *** studies suggest that the DNA nanodevice leads to reeducation of tumor-associated macrophages and ultimately to reversing the tumor immune *** strategy for aptamer-mediated and vehicle-free delivery of immunostimulatory oligonucleotides provides a potential platform for cancer immunotherapy.

关键词： aptamer immunostimulatory oligonucleotides DNA nanodevice tumor-associated macrophages cancer therapy

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Quantitative characterizations of anisotropic dynamic properties in organic-rich shale with different kerogen content

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Petroleum Science 2024年第2期21卷 855-865页

作者： jian-Yong Xie Yan-Ping Fang Xing-Hua Wu jian'er zhao Jun-Cheng Dai Jun-Xing Cao Ji-Xin Deng State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation Chengdu University of TechnologyChengdu610059SichuanChina Key Lab of Earth Exploration&Information Techniques of Ministry of Education Geophysical InstituteChengdu University of TechnologyChengdu610059SichuanChina PetroChina Southwest Oil&Gasfield Company Chengdu610017SichuanChina

Understanding the quantitative responses of anisotropic dynamic properties in organic-rich shale with different kerogen content(KC)is of great significance in hydrocarbon exploration and *** controlled experiments with a single variable is challenging for natural shales due to their high variations in components,diagenesis conditions,or pore *** employed the hot-pressing technique to construct 11 well-controlled artificial shale with varying *** artificial shale samples were successive machined into prismatic shape for ultrasonic measurements along different *** revealed bedding perpendicular P-wave velocities are more sensitive to the increasing KC than bedding paralleling velocities due to the preferential alignments of *** elastic stiffnesses except C_(13)are generally decreasing with the increasing KC,the variation of C_(1) and C_(33)on kerogen content are more sensitive than those of C_(44)and C_(66).Apparent dynamic mechanical parameters(v and E)were found to have linear correlation with the true ones from complete anisotropic equations independent of KC,which hold value towards the interpretation of well logs consistently across formations,Anisotropic mechanical parameters(ΔE and brittlenessΔB)tend to decrease with the reducing KC,withΔB showing great sensitivity to KC *** the range of low KC(10%)shale,compilation of data from natural organic rich-shales globally verified the similar systematic relationships that can be empirically used to predict the fraction of KC in shales.

关键词： Elastic properties Organic shale Anisotropy Kerogen content Physical modeling

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Highly selective adsorption of rhenium by amyloid-like protein material

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Science China(Technological Sciences) 2024年第5期67卷 1417-1430页

作者： MUHAMMAD Arif YANG QingMin KANWAL Aisha zhao jian NAWAZ Mohsan REN Hao YANG Peng Key Laboratory of Applied Surface and Colloid Chemistry Ministry of Education Xi’an Key Laboratory of Polymeric Soft Matter International Joint Research Center on Functional Fiber and Soft Smart TextileSchool of Chemistry and Chemical EngineeringShaanxi Normal UniversityXi’an710119China School of Chemistry and Chemical Engineering Northwestern Polytechnical UniversityXi’an710072China

Rhenium separation from molybdenum in molybdenite minerals and waste leachate has become an emerging *** this challenge,we prepared a set of protein-based alkylamine/alkylammonium salts complexes as extractants for selective uptake of rhenium from molybdenum,where the protein component turned into the insoluble amyloid-like structure when its internal disulfide bonds were reduced,namely phase-transition *** them,the phase-transited lysozyme and methyletrioctyleammonium chloride complex(PTL-N263)exhibited the most efficient adsorption at the alkaline condition for the electrostatic interaction between negatively charged metal ions with positively charged center(R_(4)N^(+))in N263,where negatively charged protein residues hindered the ion exchange of Cl^(-)in N263 for larger size Mo species(Mo_(7)O_(24)^(6-))than smaller size Re species(ReO^(4-)).The adsorption follows the Freundlich model and pseudo-second-order kinetics,which exhibits toplevel adsorption performance with a maximum adsorption capacity of 124 mg/g and a separation factor(β_(Re/Mo))of 2.78×10^(3)for *** adsorption capacity per unit area(57.2 mg/(g m^(2)))is 1.6–41 times higher than previously reported adsorbents,and the cost for adsorbing 1 g of Re(VII)is$1.07,indicating its industrial *** adsorption strategy can be applied to separating Re from Mo in binary solutions and industrial wastewater with other competing ions.

关键词： amyloid phase-transited lysozyme selective adsorption rhenium waste leachate solution

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The Synergized Quality Improvement Program in Teacher Education:A Policy for Improving the Quality of China's Rural Teachers

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ECNU Review of Education 2024年第2期7卷 442-452页

作者：赵健 School of Teacher Development East China Normal University3663 North Zhongshan RoadShanghai 200062China

Purpose This study elucidates the rationale,implementation,values,and challenges of the Synergized Quality Improvement Program in Teacher Education(SQIPTE)—the first policy specifically dedicated to the development of teaching staff since the founding of the People's Republic of ***/Approach/Methods After introducing the primary structure and rationale of the SQIPTE,this study reviews the existing data and research to explain why the program focuses on local normal colleges and determine how it could be implemented more *** In establishing group-based assistance under the principle of“1+M+N”(M≥N),the SQIPTE seeks to make normal colleges the primary force in the education of rural teachers and explores a collaborative operating mechanism to this *** suggests that this innovative program will provide new practical experience for the collaborative development and quality improvement of ***/Value This study reviews the SQIPTE as a new Chinese intervention to improve the quality of rural *** is strong evidence to suggest that this innovative program will inspire the construction of collaborative operating mechanisms incorporating multiple resources for teacher education systems across different areas.

关键词： Local normal college rural teacher Synergized Quality Improvement Program in Teacher Education teacher quality policy

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Mechanism underlying the effects of exercise against type 2 diabetes:A review on research progress

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World Journal of Diabetes 2024年第8期15卷 1704-1711页

作者： Chen-jian Peng Shuo Chen Su-Ying Yan jian-Ning zhao Zhi-Wen Luo Yuan Qian Guo-Liang zhao Department of Sports Medicine Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese MedicineNanjing 210022Jiangsu ProvinceChina Department of Sports Medicine Huashan HospitalFudan UniversityShanghai 200040China Department of Outpatient Nanjing Hospital of Chinese Medicine affiliated to Nanjing University of Chinese MedicineNanjing 210006Jiangsu ProvinceChina

Exercise has emerged as one of the important and effective non-drug therapies used for management of type 2 diabetes(T2D)in certain *** present report summarizes the latest findings from the research on the beneficial effect of exercise on *** objectives were to provide references for the theoretical study and the clinical practice of exercise-based management of T2D,in addition to identify the limitations of the existing literature,thereby provide direction for future research in this field.

关键词： Type 2 diabetes Diabetes Exercise Mechanism Inflammation

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In-situ U-Pb Dating of Quartz:A Preliminary Study

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Journal of Earth Science 2024年第2期35卷 726-728页

作者： Entao Liu jian-Xin zhao Songqi Pan Detian Yan Hua Wang Hubei Key Laboratory of Marine Geological Resources China University of GeosciencesWuhan 430074China Radiogenic Isotope Facility School of Earth and Environmental SciencesThe University of QueenslandBrisbane Qld 4072Australia PetroChina Research Institute of Petroleum Exploration&Development Beijing 100083China Key Laboratory of Tectonics and Petroleum Resources Ministry of EducationChina University of GeosciencesWuhan 430074China

CHALLENGES AND RESEARCH PROGRESS Recent advancements in analytical capabilities and the precision of measuring instruments in in-situ laser ablation mass spectrometry(LA-MC-ICPMS)have markedly broad ened the utility of the U-Pb isotopic *** progress has paved the way for accurately determining the ab solute ages of minerals with low uranium *** re cent years,in-situ U-Pb dating has witnessed rapid advance ments across diverse mineral types,encompassing calcite,dolo mite,fluorite,nacrite,anatase,and wolframite(Roberts et al.,2020).

关键词： dating minerals isotopic

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Role Dynamic Allocation of Human-Robot Cooperation Based on Reinforcement Learning in an Installation of Curtain Wall

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工程与科学中的计算机建模(英文) 2024年第1期138卷 473-487页

作者： Zhiguang Liu Shilin Wang jian zhao jianhong Hao Fei Yu School of Control and Mechanical Engineering Tianjin Chengjian UniversityTianjin300384China Comprehensive Business Department CATARC(Tianjin)Automotive Engineering Research Institute Co.Ltd.300339China School of Mechanical Engineering Hebei University of TechnologyTianjin300130China

A real-time adaptive roles allocation method based on reinforcement learning is proposed to improve humanrobot cooperation performance for a curtain wall installation *** method breaks the traditional idea that the robot is regarded as the follower or only adjusts the leader and the follower in *** this paper,a self-learning method is proposed which can dynamically adapt and continuously adjust the initiative weight of the robot according to the change of the ***,the physical human-robot cooperation model,including the role factor is ***,a reinforcement learningmodel that can adjust the role factor in real time is established,and a reward and actionmodel is *** role factor can be adjusted continuously according to the comprehensive performance of the human-robot interaction force and the robot’s Jerk during the repeated ***,the roles adjustment rule established above continuously improves the comprehensive *** of the dynamic roles allocation and the effect of the performance weighting coefficient on the result have been *** results show that the proposed method can realize the role adaptation and achieve the dual optimization goal of reducing the sum of the cooperator force and the robot’s Jerk.

关键词： Human-robot cooperation roles allocation reinforcement learning

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Magnetocaloric effect and phase transition critical behavior of La0.75Sr0.25Mn0.9Co0.1O3 compound synthesized under the high pressure

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Tungsten 2024年第03期6卷 621-632页

作者： Jing zhao Lei Gao jian-Jun zhao Wei Wei Hui-Qin Yun Ru Xing Huai-Jin Ma Xiang Jin Luo-Meng Chao School of Physical Science and Technology Key Laboratory of Magnetism and Magnetic Materials for Higher Education in Inner Mongolia Autonomous Region Baotou Teachers' College National Key Laboratory of Baiyunobo Rare Earth Resource Research and Comprehensive Utilization Baotou Research Institute of Rare Earths School of Physics and Electronic Information Inner Mongolia Normal University College of Science Inner Mongolia University of Science and Technology

In this study,a novel method is proposed for producing perovskite rare-earth manganese oxide magnetic refrigeration materials that exhibit superior properties compared to similar *** maximum magnetic entropy change values for this sample are 1.44 and 3.75 J·kg-1·K-1for magnetic fields of 2 and 7 T,***,its relative cooling power has been calculated to be 101.96 and 404.78 J·kg-1,indicating good *** results were obtained using the sample synthesized under a pressure of 4 GPa,and the sample has undergone a second phase *** critical behavior of the sample fits well with the mean field *** different magnetic fields,there is a significant overlap between the values of the maximum magnetic entropy change and the temperature-averaged entropy change,indicating that the refrigeration performance of the sample after high pressure can approach its maximum capability.

关键词： High-pressure synthesis Magnetocaloric effect Relative cooling power Magnetic phase transition

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Role of CD36 in central nervous system diseases

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Neural Regeneration Research 2024年第3期19卷 512-518页

作者： Min Feng Qiang Zhou Huimin Xie Chang Liu Mengru Zheng Shuyu Zhang Songlin Zhou jian zhao School of Health Science and Engineering University of Shanghai for Science and TechnologyShanghaiChina Department of Orthopedic Oncology Second Affiliated Hospital of Naval Medical UniversityShanghaiChina Key Laboratory of Neuroregeneration of jiangsu and Ministry of Education NMPA Key Laboratory for Research and Evaluation of Tissue Engineering Technology ProductsJiangsu Clinical Medicine Center of Tissue Engineering and Nerve Injury RepairCo-Innovation Center of NeuroregenerationNantong UniversityNantongJiangsu ProvinceChina Department of Stomatology Affiliated Hospital of Nantong UniversityNantongJiangsu ProvinceChina Medical College of Nantong University NantongJiangsu ProvinceChina

CD36 is a highly glycosylated integral membrane protein that belongs to the scavenger receptor class B family and regulates the pathological progress of metabolic ***36 was recently found to be widely expressed in various cell types in the nervous system,including endothelial cells,pericytes,astrocytes,and ***36 mediates a number of regulatory processes,such as endothelial dysfunction,oxidative stress,mitochondrial dysfunction,and inflammatory responses,which are involved in many central nervous system diseases,such as stroke,Alzheimer’s disease,Parkinson’s disease,and spinal cord ***36 antagonists can suppress CD36 expression or prevent CD36 binding to its ligand,thereby achieving inhibition of CD36-mediated pathways or ***,we reviewed the mechanisms of action of CD36 antagonists,such as Salvianolic acid B,tanshinone IIA,curcumin,sulfosuccinimidyl oleate,antioxidants,and small-molecule ***,we predicted the structures of binding sites between CD36 and *** sites can provide targets for more efficient and safer CD36 antagonists for the treatment of central nervous system diseases.

关键词： animal experiments antagonists CD36 antagonist central nervous system diseases clinical trial curcumin microRNA salvianolic acid B small-molecule drugs sulfosuccinimidyl oleate

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