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Multi-functional vanadium dioxide integrated metamaterial for terahertz wave manipulation

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Chinese Physics B 2020年第9期29卷 331-336页

作者： jian-xing zhao jian-Lin Song Yao Zhou Rui-Long zhao Yi-Chao Liu jian-Hong Zhou School of Photoelectric Engineering Changchun University of Science and TechnologyChangchun 130022China Key Laboratory of Optoelectric Measurement and Optical Information Transmission Technology of Ministry of Education Changchun University of Science and TechnologyChangchun 130022China

We proposed a vanadium dioxide(VO2)-integrated multi-functional metamaterial structure that consists of three metallic grating layers and two VO2 films separated by SiO2 dielectric *** proposed structure can be flexibly switched among three states by adjusting temperature,incident direction,and *** state 1,the incident wave is strongly transmitted and perfectly converted to its orthogonal polarization *** state 2,the incident wave is perfectly *** state 3,incident wave is totally reflected *** working frequency of the multi-functional metamaterial can be arbitrarily tuned within a broad pass *** believe that our findings are beneficial in designing temperature-controlled metadevices.

关键词： metamaterial vanadium dioxide multi-functionality

Switching between the Functions of Half-Wave Plate and Quarter-Wave Plate Simply by Using a Vanadium Dioxide Film in a Terahertz Metamaterial

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Chinese Physics Letters 2020年第6期37卷 35-39页

作者： jian-xing zhao jian-Lin Song Yao Zhou Yi-Chao Liu jian-Hong Zhou School of Photoelectric Engineering Changchun University of Science and TechnologyChangchun 130022China Key Laboratory of Optoelectric Measurement and Optical Information Transmission Technology(Ministry of Education) Changchun University of Science and TechnologyChangchun 130022China

We propose a switchable THz metamaterial that can be switched between two functions of half-wave plate and quarter-wave *** two switchable functions can be simply achieved by inserting a VO2 film in the metamaterial ***-difference time-domain(FDTD)simulation results show that the proposed metamaterial can convert x-polarized incident wave to y-polarized reflected wave when VO2 is at metal phase,and convert x-polarized wave to circularly polarized wave when VO2 is at insulator *** metamaterial performs well in the two functions,i.e.,the same broad working frequency band and near perfect polarization *** switching effect originates from the switchable Fabry-Perot cavity length induced by the phase change of *** believe that our findings provide a reference in designing switchable metamaterials.

关键词： polarized wave circular

Val 70, Phe 72 and the last seven amino acid residues of C-terminal are essential to the function of norepinephrine transporter

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Cell Research 1998年第4期8卷 311-315页

作者： LIU YAN HONG FANG HUANG jian FEI jian xing zhao QUANG BAO GU WOLFGANG SCHWARZ LI HE GUO (Shanghai Institute of Cell Biology, Chinese Academy of Sciences, Shanghai 200031, China)(Max-Plank Institute for Biophysik, Kennedy allee 70,60596 Frankfurt/M G Max-Plank Institute for Biophysik Kennedy allee 70 Frankfurt/M 60596 Germany

The norepinephrine transporter(NET) is a member of the Na+/Cl- dependent neurotransmitter transporter family and constitutes the target of several clinically important antidepressants. To delineate the critical amino acid residues and the function of C-terminal in regulating transport activity of NET, here we constructed two site mutants (V70F, F72V; V70I, F72V) and one C-terminal truncated mutant (△611-617). The wild type and mutants of NET were expressed in Xenopus oocytes by injection of their cRNA. We found that all of these mutants lost their transport activity. These results indicate that the amino acid residues of V70 and F72 3 and the last seven amino acids of C-terminal are essential to the transport activity of NET.

关键词： Norepinephrine transporter neurotransmitter uptake mutagenesis

Association between intra-pancreatic fat deposition and diseases of the exocrine pancreas: A narrative review

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World Journal of Gastroenterology 2025年第2期31卷 27-41页

作者： Jing Ye jian-Guo Wang Rong-Qiang Liu Qiao Shi Wei-xing Wang Department of General Surgery Renmin Hospital of Wuhan UniversityWuhan 430060Hubei ProvinceChina Department of Pancreatic Surgery Renmin Hospital of Wuhan UniversityWuhan 430060Hubei ProvinceChina

Intrapancreatic fat deposition(IPFD)has garnered increasing attention in recent *** prevalence of IPFD is relatively high and associated with factors such as obesity,age,and ***,the pathophysiological mechanisms underlying IPFD remain unclear,with several potential contributing factors,including oxida-tive stress,alterations in the gut microbiota,and hormonal *** was found to be highly correlated with the occurrence and prognosis of exocrine pan-creatic *** imaging techniques remain the primary diagnostic approach for IPFD,an expanding array of biomarkers and clinical scoring systems have been identified for screening ***,effective treatments for IPFD are not available;however,existing medications,such as glucagon-like peptide-1 receptor agonists,and new therapeutic approaches explored in animal models have shown considerable potential for managing this *** paper reviews the pathogenesis of IPFD,its association with exocrine pancreatic disea-ses,and recent advancements in its diagnosis and treatment,emphasizing the significant clinical relevance of IPFD.

关键词： Intrapancreatic fat deposition Pancreatic steatosis Nonalcoholic fatty pancreas disease Pancreatitis Pancreatic cancer

Loss-of-function mutations of microRNA-142-3p promote ASH1L expression to induce immune evasion and hepatocellular carcinoma progression

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World Journal of Gastroenterology 2025年第1期31卷 126-145页

作者： xing-Hui Yu Yan Xie jian Yu Kun-Ning Zhang Zhou-Bo Guo Di Wang zhao-Xian Li Wei-Qi Zhang Yu-Ying Tan Li Zhang Wen-Tao jiang School of Medicine Nankai UniversityTianjin 300192China Tianjin Key Laboratory of Molecular Diagnosis and Treatment of Liver Cancer Tianjin First Center HospitalTianjin 300192China Department of Liver Transplantation Tianjin First Center HospitalTianjin 300192China First Central Clinical School Tianjin Medical UniversityTianjin 300192China

BACKGROUND Hepatocellular carcinoma(HCC)has been a pervasive malignancy throughout the world with elevated *** therapeutic targets are beneficial to treat and predict the ***,the exact molecular mechanisms leading to the progression of HCC are still *** has shown that the microRNA-142-3p level decreases in HCC,whereas bioinformatics analysis of the cancer genome atlas database shows the ASH1L expression increased among liver tumor *** this paper,we will explore the effects and mechanisms of microRNA-142-3p and ASH1L affect the prognosis of HCC patients and HCC cell bioactivity,and the association between *** To investigate the effects and mechanisms of microRNA-142-3p and ASH1L on the HCC cell bioactivity and prognosis of HCC *** In this study,we grouped HCC patients according to their immunohistochemistry results of ASH1L with pathological tissues,and retrospectively analyzed the prognosis of HCC ***,explored the roles and mechanisms of microRNA-142-3p and ASH1L by cellular and animal experiments,which involved the following experimental methods:Immunohistochemical staining,western blot,quantitative real-time-polymerase chain reaction,flow cytometric analysis,tumor xenografts in nude mice,*** statistical methods involved in this study contained t-test,one-way analysis of variance,theχ^(2)test,the Kaplan-Meier approach and the log-rank *** In this study,we found that HCC patients with high expression of ASH1L possess a more recurrence rate as well as a decreased overall survival ***1L promotes the tumorigenicity of HCC and microRNA-142-3p exhibits reduced expression in HCC tissues and interacts with ASH1L through targeting the ASH1L 3′untranslated ***,microRNA-142-3p promotes apoptosis and inhibits proliferation,invasion,and migration of HCC cell lines in vitro via *** the exploration mechanism,we found ASH1L may promote an immunosuppressive mi

关键词： Hepatocellular carcinoma MicroRNA-142-3p ASH1L Immune evasion Tumor immune microenvironment Apoptosis

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汽车自适应巡航系统的多性能指标控制算法

机械科学与技术 2018年第5期37卷 690-697页

作者：凌滨宋梦实邢键赵永辉东北林业大学机电工程学院哈尔滨150040

针对汽车自适应巡航控制系统的多性能指标不协调及不完善的问题,综合考虑汽车的多性能指标和汽车自身的驱动和制动能力,提出一种基于模型预测控制和最优控制的汽车自适应巡航控制算法。根据本车与前车之间的相互纵向运动学特性,建立离... 详细信息

针对汽车自适应巡航控制系统的多性能指标不协调及不完善的问题,综合考虑汽车的多性能指标和汽车自身的驱动和制动能力,提出一种基于模型预测控制和最优控制的汽车自适应巡航控制算法。根据本车与前车之间的相互纵向运动学特性,建立离散状态空间表达式,引入饱和函数,并以输出变量的加权平方和作为协调多性能指标的目标函数,最后将目标函数的求解问题转化为一维极值问题进行求解。仿真结果验证了算法对安全车距保持的有效性和协调多性能指标的可行性。

关键词：自适应巡航系统多性能指标模型预测控制约束函数

Prognostic model for esophagogastric variceal rebleeding after endoscopic treatment in liver cirrhosis: A Chinese multicenter study

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World Journal of Gastroenterology 2025年第2期31卷 85-101页

作者： Jun-Yi Zhan Jie Chen Jin-Zhong Yu Fei-Peng Xu Fei-Fei xing De-Xin Wang Ming-Yan Yang Feng xing jian Wang Yong-Ping Mu Cell Biology Laboratory Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghai 201203China Institute of Liver Diseases Shanghai Academy of Chinese MedicineShanghai 201203China Clinical Key Laboratory of Traditional Chinese Medicine of Shanghai Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghai 201203China Key Laboratory of Liver and Kidney Disease of the Ministry of Education Shanghai University of Traditional Chinese MedicineShanghai 201203China Department of Gastroenterology and Hepatology Zhongshan Hospital Affiliated to Fudan UniversityShanghai 200032China Shanghai Institute of Liver Disease Fudan UniversityShanghai 200032China Evidence-Based Medicine Center Fudan UniversityShanghai 200032China Department of Gastrointestinal Endoscopy Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghai 201203China Department of Hepatology Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghai 201203China

BACKGROUND Rebleeding after recovery from esophagogastric variceal bleeding(EGVB)is a severe complication that is associated with high rates of both incidence and *** its clinical importance,recognized prognostic models that can effectively predict esophagogastric variceal rebleeding in patients with liver cirrhosis are *** To construct and externally validate a reliable prognostic model for predicting the occurrence of esophagogastric variceal *** This study included 477 EGVB patients across 2 cohorts:The derivation cohort(n=322)and the validation cohort(n=155).The primary outcome was rebleeding events within 1 *** least absolute shrinkage and selection operator was applied for predictor selection,and multivariate Cox regression analysis was used to construct the prognostic *** validation was performed with bootstrap *** assessed the discrimination,calibration and accuracy of the model,and performed patient risk *** Six predictors,including albumin and aspartate aminotransferase concentrations,white blood cell count,and the presence of ascites,portal vein thrombosis,and bleeding signs,were selected for the rebleeding event prediction following endoscopic treatment(REPET)*** predicting rebleeding within 1 year,the REPET model ex-hibited a concordance index of 0.775 and a Brier score of 0.143 in the derivation cohort,alongside 0.862 and 0.127 in the validation ***,the REPET model revealed a significant difference in rebleeding rates(P<0.01)between low-risk patients and intermediate-to high-risk patients in both *** We constructed and validated a new prognostic model for variceal rebleeding with excellent predictive per-formance,which will improve the clinical management of rebleeding in EGVB patients.

关键词： Esophagogastric variceal bleeding Variceal rebleeding Liver cirrhosis Prognostic model Risk stratification Secondary prophylaxis

HPM Absorption Caused by Self-action Phenomenon in the Lower Ionosphere

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HPM Absorption Caused by Self-action Phenomenon in the Lower...

IEEE 2005 International Symposium on Microwave, Antenna, Propagation and EMC Technologies for Wireless Communications

作者： Shao Ying Niu Zhong-xia Yang jian-hong xing zhao-wei Cao Jin-kun (Department of communication and engineering, Information Engineering University, ZhengZhou 450002, China)

-HPM may cause many non-linear effects when it propagates in the ionosphere. HPM self-action phenomenon is one of the nonlinear effects which could influence HPM propagation notably. This paper analys

关键词： HPM, D layer, Absorption, Selfaction.

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基于模糊PID的汽车防抱死制动系统

计算机仿真 2018年第10期35卷 166-170,192页

作者：凌滨宋梦实邢键赵永辉东北林业大学机电工程学院黑龙江哈尔滨150040

针对以往汽车防抱死制动系统的控制性能不稳定、响应速度慢、控制精度低等问题,传统的逻辑门限控制算法以及单一的模糊控制算法和PID控制算法难以满足系统的要求,因此采用模糊控制算法与PID控制算法相结合的控制方法设计了一种基于滑移... 详细信息

针对以往汽车防抱死制动系统的控制性能不稳定、响应速度慢、控制精度低等问题,传统的逻辑门限控制算法以及单一的模糊控制算法和PID控制算法难以满足系统的要求,因此采用模糊控制算法与PID控制算法相结合的控制方法设计了一种基于滑移率的ABS控制器,并设计了路面识别系统,使汽车能够在不同的路面上自动选择最佳滑移率。利用Matlab/Simulink进行仿真,并与PID控制进行对比。仿真结果表明,模糊PID控制算法在响应速度、稳定性以及控制精度上都优于PID控制算法。

关键词：防抱死制动系统路面识别模糊控制