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Changes in Climate Factors and Extreme Climate Events in South China during 1961-2010

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Advances in Climate Change Research 2013年第1期4卷 1-11页

作者： DU Yao-Dong AI Hui DUAN Hai-Lai HU Ya-Min WANG Xian-Wei HE jian WU Hong-yu WU Xiao-Xuan Regional Climate Center of South China Center of Integrated Geographic Information Analysis School of Geography and Planning/Guangdong Key Laboratory for Urbanization and Geo-Simulation Sun Yat-Sen University

Daily climate data at 110 stations during 1961-2010 were selected to examine the changing characteristics of climate factors and extreme climate events in South China. The annual mean surface air temperature has increased significantly by 0.16℃ per decade, most notably in the Pearl River Delta and in winter. The increase rate of the annual extreme minimum temperature (0.48℃ per decade) is over twice that of the annual extreme maximum temperature (0.20℃ per decade), and the increase of the mean temperature is mainly the result of the increase of the extreme minimum temperature. The increase rate of high-temperature days (1.1 d per decade) is close to the decrease rate of low-temperature days (-1.3 d per decade). The rainfall has not shown any significant trend, but the number of rainy days has decreased and the rain intensity has increased. The regional mean sunshine duration has a significant decreasing trend of -40.9 h per decade, and the number of hazy days has a significant increasing trend of 6.3 d per decade. The decrease of sunshine duration is mainly caused by the increase of total cloud, not by the increase of hazy days in South China. Both the regional mean pan evaporation and mean wind speed have significant decreasing trends of -65.9 mm per decade and -0.11 m s-1 per decade, respectively. The decrease of both sunshine duration and mean wind speed plays an important role in the decrease of pan evaporation. The number of landing tropical cyclones has an insignificant decreasing trend of -0.6 per decade, but their intensities show a weak increasing trend. The formation location of tropical cyclones landing in South China has converged towards 10-19°N, and the landing position has shown a northward trend. The date of the first landfall tropical cyclone postpones 1.8 d per decade, and the date of the last landfall advances 3.6 d per decade, resulting in reduction of the typhoon season by 5.4 d per decade.

关键词： climate factors extreme climate events climate change South China

Multidisciplinary team therapy for left giant adrenocortical carcinoma: A case report

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World Journal of Clinical Cases 2021年第20期9卷 5737-5743页

作者： Zheng Zhou Hong-Mei Luo jian Tang Wu-Jun Xu Bin-Hui Wang Xu-Hui Peng Heng Tan Li Liu Xiang-Yang Long yu-De Hong Xiao-Bin Wu jian-Ping Wang Bai-Qi Wang Hai-Hui Xie Yong Fang Yong Luo Rong Li Yi Wang Department of Urology The Second Affiliated HospitalUniversity of South ChinaHengyang 421001Hunan ProvinceChina Department of Histology and Embryology Clinical Anatomy and Reproductive Medicine Application InstituteUniversity of South ChinaHengyang 421001Hunan ProvinceChina Department of Endocrinology The Second Affiliated Hospital of University of South ChinaHengyang 421001Hunan ProvinceChina Department of Oncology The Second Affiliated HospitalUniversity of South ChinaHengyang 421001Hunan ProvinceChina Department of Radiotherapy The Second Affiliated HospitalUniversity of South ChinaHengyang 421001Hunan ProvinceChina Department of Pathology The Second Affiliated HospitalUniversity of South ChinaHengyang 421001Hunan ProvinceChina Department of ICU The Second Affiliated HospitalUniversity of South ChinaHengyang 421001Hunan ProvinceChina Department of Clinical Pharmacy The Second Affiliated HospitalUniversity of South ChinaHengyang 421001Hunan ProvinceChina

BACKGROUND Adrenocortical carcinoma(ACC)is a rare malignant epithelial tumor originating from adrenocortical cells that carries a very poor *** or inoperable diseases are often considered incurable,and treatment remains a *** for advanced cases such as ACC complicated with renal venous cancer thrombus,there are few cumulative cases in the *** SUMMARY The patient in this case was a 39-year-old middle-aged male who was admitted to the hospital for more than half a month due to dizziness and chest *** tomography(CT)findings after admission revealed a left retroperitoneal malignant space-occupying lesion,but the origin of the formation of the left renal vein cancer thrombus remained to be *** was speculated that it originated from the left adrenal gland,perhaps a retroperitoneal source,and left adrenal mass+left nephrectomy+left renal vein tumor thrombus removal+angioplasty were performed under general *** pathology results indicated a diagnosis of *** steroid therapy was *** 3 mo after surgery,abdominal CT reexamination revealed multiple enlarged retroperitoneal lymph nodes and multiple low-density shadows in the liver,and palliative radiotherapy and mitotane were administered,considering the possibility of *** patient is currently being followed *** ACC is a highly malignant *** if the tumor is removed surgically,there is still the possibility of *** mitotane and adjuvant chemoradiotherapy have certain benefits for patients,but they cannot fully offset the poor prognosis of this disease.

关键词： Adrenocortical carcinoma Ki-67 Multidisciplinary team Cancer thrombus Mitotane Case report

丙烯腈-苯乙烯共聚物对聚甲醛的热稳定化作用

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高等学校化学学报 2015年第9期36卷 1853-1858页

作者：刘经纬郭朝霞于建清华大学化工系先进材料教育部重点实验室北京100084

研究了丙烯腈-苯乙烯(AS)共聚物对聚甲醛(POM)的热稳定化作用.结果表明,在动态混炼条件下,添加少量的AS共聚物可使POM的熔体稳定性和熔融滞留时间明显增大,AS最优添加质量分数为3%;在静态加热条件下,AS的加入可使POM在升温过程中的分解... 详细信息

研究了丙烯腈-苯乙烯(AS)共聚物对聚甲醛(POM)的热稳定化作用.结果表明,在动态混炼条件下,添加少量的AS共聚物可使POM的熔体稳定性和熔融滞留时间明显增大,AS最优添加质量分数为3%;在静态加热条件下,AS的加入可使POM在升温过程中的分解温度显著提高,在恒温过程中的失重率明显降低.在动态或静态条件下,AS共聚物对POM热稳定性的贡献效果一致,并且同时加入AS和三聚氰胺对POM的热稳定性改善更为显著.红外分析结果表明,AS对POM的热稳定化作用源于分子链上的氰基对甲醛的有效吸收.

关键词：聚甲醛丙烯腈-苯乙烯共聚物热稳定性

新型平板式固体氧化物燃料电池的开发和性能分析

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动力工程 2008年第6期28卷 949-954页

作者：王玉璋于建国惠宇翁史烈上海交通大学机械与动力工程学院动力机械及工程国家教育部重点实验室上海200240

利用商业数值分析软件和试验获得的电池各部件材料性能数据,改进了用于分析固体氧化物燃料电池(SOFC)单电池内部复杂物理过程的软件包.应用该软件包,得到了设计的新型高效平板式SOFC单电池内部各气体组分浓度、温度、电势、电流及电流... 详细信息

利用商业数值分析软件和试验获得的电池各部件材料性能数据,改进了用于分析固体氧化物燃料电池(SOFC)单电池内部复杂物理过程的软件包.应用该软件包,得到了设计的新型高效平板式SOFC单电池内部各气体组分浓度、温度、电势、电流及电流密度等参数的分布规律.分析结果表明:在高燃料利用率情况下,阳极内组分扩散引起的浓度极化损失是影响电池性能的重要因素之一.该新型结构电池可有效改善电池的密封性,但其电解质需要较高的最大离子传导率.

关键词：能源系统工程固体氧化物燃料电池传热传质电化学反应电流场

Texture branch network for chronic kidney disease screening based on ultrasound images

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Frontiers of Information Technology & Electronic Engineering 2020年第8期21卷 1161-1170页

作者： Peng-yi HAO Zhen-yu XU Shu-yuan TIAN Fu-li WU Wei CHEN jian WU Xiao-nan LUO College of Computer Science and Technology Zhejiang University of TechnologyHangzhou 310023China Tongde Hospital of Zhejiang Province Hangzhou 310012China The First Affiliated Hospital Zhejiang UniversityHangzhou 310003China College of Computer Science and Technology Zhejiang UniversityHangzhou 310027China Real Doctor AI Research Center Zhejiang UniversityHangzhou 310027China Institute of Artificial Intelligence Guilin University of Electronic TechnologyGuilin 541004China

Chronic kidney disease(CKD) is a widespread renal disease throughout the world. Once it develops to the advanced stage, serious complications and high risk of death will follow. Hence, early screening is crucial for the treatment of CKD. Since ultrasonography has no side effects and enables radiologists to dynamically observe the morphology and pathological features of the kidney, it is commonly used for kidney examination. In this study,we propose a novel convolutional neural network(CNN) framework named the texture branch network to screen CKD based on ultrasound images. This introduces a texture branch into a typical CNN to extract and optimize texture features. The model can automatically generate texture features and deep features from input images, and use the fused information as the basis of classification. Furthermore, we train the base part of the network by means of transfer learning, and conduct experiments on a dataset with 226 ultrasound images. Experimental results demonstrate the effectiveness of the proposed approach, achieving an accuracy of 96.01% and a sensitivity of 99.44%.

关键词： Chronic kidney disease Ultrasound Texture branch network Transfer learning

A Genetic Linkage Map of Brassica campestris ***. pekinensis (syn. B. rapa L. ssp. pekinensis)

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Agricultural Sciences in China 2003年第1期2卷 49-55页

作者： yu Shuan-cang, WANG Yong-jian and ZHENG Xiao-yingBeijing Vegetable Research Center, Beijing 100089 , P. R. China

A molecular genetic map of Chinese cabbage was constructed with a 102 recombinant inbred (RI) population from a cross of two cultivated Chinese cabbage lines 177 and 276, using AFLP and RAPD markers. 352 markers including 265 AFLP markers and 87 RAPD markers were integrated into 17 linkage groups. It covered a total of 2 665. 7 cM with an average interval of 7. 6 cM. AFLP marker is efficient for map construction while it easily forms clusters to cause big gaps in map. A total of 13.92 % abnormal segregation markers distributed in the map. The molecular genetic map is fundamental for gene localization, comparative genomics, and QTL mapping of important agronomic traits.

关键词： Brassica campestris L. ssp. pekinensis(syn. B. rapa L. ssp. pekinensis) Genetic linkage map AFLP RAPD

Nomograms for pre-and postoperative prediction of long-term survival among proximal gastric cancer patients: A large-scale,single-center retrospective study

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World Journal of Clinical Cases 2019年第21期7卷 3419-3435页

作者： Qi-yue Chen Zhi-Liang Hong Qing Zhong Zhi-yu Liu Xiao-Bo Huang Si-Jin Que Ping Li jian-Wei Xie Jia-Bin Wang jian-Xian Lin Jun Lu Long-Long Cao Mi Lin Ru-Hong Tu Chao-Hui Zheng Chang-Ming Huang Department of Gastric Surgery Fujian Medical University Union HospitalFuzhou 350001Fujian ProvinceChina Department of General Surgery Fujian Medical University Union HospitalFuzhou 350001Fujian ProvinceChina Key Laboratory of the Ministry of Education of Gastrointestinal Cancer Fujian Medical UniversityFuzhou 350001Fujian ProvinceChina Fujian Key Laboratory of Tumor Microbiology Fujian Medical UniversityFuzhou 350001Fujian ProvinceChina

BACKGROUND The incidence of proximal gastric cancer(GC)is increasing,and methods for the prediction of the long-term survival of proximal GC patients have not been well *** To develop nomograms for the prediction of long-term survival among proximal GC *** Between January 2007 and June 2013,we prospectively collected and retrospectively analyzed the medical records of 746 patients with proximal GC,who were divided into a training set(n=560,75%)and a validation set(n=186,25%).A Cox regression analysis was used to identify the preoperative and postoperative risk factors for overall survival(OS).RESULTS Among the 746 patients examined,the 3-and 5-year OS rates were 66.1%and 58.4%,*** the training set,preoperative T stage(cT),N stage(cN),CA19-9,tumor size,ASA core,and 3-to 6-mo weight loss were incorporated into the preoperative nomogram to predict the *** addition to these variables,lymphatic vascular infiltration(LVI),postoperative tumor size,T stage,N stage,blood transfusions,and complications were incorporated into the postoperative *** calibration curves used to determine the OS probability fit *** the training set,the preoperative nomogram achieved a C-index of 0.751[95%confidence interval(CI):0.732-0.770]in predicting OS and accurately stratified the patients into four prognostic subgroups(5-year OS rates:86.8%,73.0%,43.72%,and 20.9%,P<0.001).The postoperative nomogram had a C-index of 0.758 in predicting OS and accurately stratified the patients into four prognostic subgroups(5-year OS rates:82.6%,74.3%,45.9%,and 18.9%,P<0.001).CONCLUSION The nomograms accurately predicted the pre-and postoperative long-term survival of proximal GC patients.

关键词： Proximal gastric cancer Preoperative Nomogram Prediction Prognosis

The Convex-cost Production Planning Disruption Recovery Problem and The Steepest Descent Method

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The Convex-cost Production Planning Disruption Recovery Prob...

Overexpression of TIMP-1 mediated by recombinant adenovirus in hepatocellular carcinoma cells inhibits proliferation and invasion in vitro

第四届运筹学及其应用国际研讨会

作者： jian Yang Xiang-Tong Qi Gang yu Department of Industrial and Manufacturing Engineering New Jersey Institute of Technology Newark NJ 07102 Department of Management Science and Information Systems Red McCombs School of Business University of Texas at Austin Austin TX 78712

＜正＞We study the problem of recovering a production plan after disruptions. Disruptions may be caused by internal and external factors such as inclement weather,power failures,market change,machine breakdowns,supply shortages,workers unavailability,and *** these disruptions can be treated as cost disruptions and demand *** the involved cost functions are convex,demand disruptions are easy to *** present the steepest descent method and find that it is more suitable than the pre-existing incremental method to tackle cost disruptions,especially when the disruptions are limited within the first or last few ***,even for the initial production planning problem, the steepest descent method is a competitive alternative to the incremental method.

关键词： Inventory/production Uncertainty Deterministic Production/scheduling Planning Networks/graphs Applications

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Hepatobiliary & Pancreatic Diseases International 2006年第3期5卷 409-415页

作者： Dong Xia Lu-Nan Yan jian-Guo Xie yu Tong Mao-Lin Yan Xin-Ping Wang Ming-Man Zhang Lan-Ying Zhao Department of General Surgery West China Hospital Sichuan University Chengdu 610041 China.

BACKGROUND: Matrix metalloproteinases (MMPs) and its natural tissue inhibitors of metalloproteinases (TIMPs) are involved in cancer progression. This study was undertaken to determine the effects of overexpression of TIMP-1 on human hepatocellular carcinoma (HCC) cell growth, proliferation,and invasion. METHODS: Employing the efficient AdEasy?system, recombinant adenovirus AdTIMP-1 containing full-length cDNA of TIMP-1 was generated by homologous recombination and amplified in 293 cells. Then, human HCC cell line (HepG2) underwent gene transfection to overexpress TIMP-1 (so-called HepG-T cells). The mRNA and protein expressions of TIMP-1 were detected with RTPCR and Western blotting, respectively. The ultrastructure was observed with a transmission electron microscope and the proliferation of HepG-T cells was determined by MTT assay and growth curve. The potential of in vitro invasion was measured with Millicell Chamber. RESULTS: The resulting AdTIMP-1 and HepG-T cells were generated and the expression of TIMP-1 was detected in vitro. The cell proliferation curves and MTT assay showed HepG-T cells’ growth, and proliferation were obviously inhibited. The invasion across Matrigel-coated filters was significantly decreased compared with controls. The suppression rate of HepG-2 cells with AdhTIMP-1 transfection was 50%, and AdhTIMP-1 transfection inhibited by more than 91.6% of the invasion into the Matrigel-coated filter (P<0.01). CONCLUSIONS: TIMP-1 overexpression results in the suppression of proliferative and invasive potential of HepG2 cells in vitro. This study demonstrates the potential role of TIMP-1 as a target for liver cancer gene therapy and has laid a foundation for further study on its anticancer function.

关键词： tissue inhibitor of metalloproteinase hepatocellular carcinoma proliferation invasion gene therapy