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Optimal phase searching of PTS using modified genetic algorithm for PAPR reduction in OFDM systems

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Science China(Information Sciences) 2014年第6期57卷 54-64页

作者： CHEN Zhi ZHANG Shuai YANG Lin jia yingying LI ShaoQian National Key Laboratory of Science and Technology on Communications University of Electronic Science and Technology of China

In this paper,a novel genetic algorithm assisted partial transmit sequence(NGA-PTS)is proposed to reduce the peak-to-average power ratio(PAPR)of orthogonal frequency division multiplexing(OFDM).However,the search complexity of the optimum PTS(OPTS)scheme is too large for the typical number of ***,some artificial intelligence methods,such as genetic algorithm technique,and particle swarm optimization,are introduced to reduce the *** traditional GA-PTS(TGA-PTS)technique risks finding a suboptimal solution,how to avoid this disadvantage of TGA-PTS is an interest *** order to obtain a better suboptimal solution,a phase factor optimal pair technique and an abandon/introduction new chromosome technique are proposed in GA *** results show that the proposed scheme achieves a significant improvement over the TGA-PTS scheme in ***,by use of the inherent diversity of constellation for each OFDM candidate,in the receiver part,the proposed scheme enables data recovery without any side *** results show the efficiency of the proposed scheme.

关键词： orthogonal frequency division multiplexing(OFDM) genetic algorithm(GA) partial transmit sequences(PTS) peak-to-average power ratio(PAPR) side information(SI)

Thymine DNA glycosylase promotes transactivation of β-catenin/TCFs by cooperating with CBP

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Journal of Molecular Cell Biology 2014年第3期8卷 231-239页

作者： yingying jia Fen Nie Aiying Du Zhangcheng Chen Yuanbo Qin Tao Huang Xiaomin Song Lin Li State Key Laboratory of Molecular Biology Institute of Biochemistry and Cell Biology Shanghai Institutes for Biological Sciences Chinese Academy of SciencesShanghai 200031 China

Thymine DNA glycosylase CrDG）, an enzyme that initiates the repair of G/T and G/U mismatches, has been lately found crucial in em- bryonic development to maintain epigenetic stability and facilitate the active DNA demethylation. Here we report a novel role of TDG in Wnt signaling as a transcriptional coactivator of β-catenin/TCFs complex. Our data show that TDG binds to the transcriptional factor family LEF1/TCFs and potentiates β-catenin/TCFs transactivation, while TDG depletion suppresses Wnt3a-stimulated reporter activity or target gene transcription. Next, we show that CBP, a known coactivator, is also required for TDG function through forming a coopera- tive complex on target promoters. Moreover, there is an elevation of TDG levels in human colon cancer tissue, and knockdown of TDG inhibits proliferation of the colon cells. Overall, our results reveal that TDG, as a new coactivator, promotes β-catenin/TCFs transacti- vation and functionally cooperates with CBP in canonical Wnt signaUng.

关键词： TDG TCF CBP Wnt signaling transactivation

Exhumation history of the Huangshan granite pluton,southern Anhui Province:New insights from fission-track analysis

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Science China Earth Sciences 2011年第4期54卷 528-539页

作者： ZHENG Yong YU XinQi YUAN WanMing WANG De'En jiaNG GongBing ZHU DeLai WANG Cheng jia yingying State Key Laboratory of Geological Processes and Mineral Resources China University ofGeosciences Beijing 100083 China Institute of Geology and Geophysics Chinese Academy of Sciences Beijing 100029 China 332 Geological Team of Anhui Bureau of Geology and Mineral Resources Huangshan 245000 China World Heritage offices Huangshan Management Council Huangshan 245800 China

The dating of the uplift onset of the Huangshan pluton in the southern part of Anhui Province associated with the collision between paleo-Pacific Block and the Eurasian Block is a fundamental issue to better understand the uplift mechanisms and the regional tectonic evolution. Х^2 values of seven zircon fission track （ZFF） samples collected from the south part of the Huangshan pluton were all 〈5%. Based on the grain ages of four typical ZFr samples, three thermal overprints ranging in 113-123, 72-95 and 49-66 Ma were distinguished respectively using the binomial peak-fitting method in accordance with the tectonic thermal events after south China shifted into circum-Pacific tectonic region. Apatite fission track （AFT） study of the Huangshan pluton shows ages lie between 15±3 and 56±6 Ma with all Х^2 values 〉5%, and all are significantly younger than their host rock formation ages, indicating that the samples have experienced post-formation thermal history. Based on the AFT resuits and topography characteristics in the Huangshan pluton, three zones with different denudation intensities caused by the differential uplift of the fault blocks were recognized in this paper, indicating that denudation was driven by the increase in elevation significantly. Modeling of the AFT data shows that the earlier cooling phase took place in the early Cenozoic and involved 3.3, 3.8 and 6.0℃/Ma of cooling rates equivalent to the exhumation rates of 90, 104 and 167 m/Ma in different fault blocks. The last phase of cooling took place from -10 Ma with average cooling rate of -5.6℃/Ma, equivalent to average denudation rates of -156 m/Ma. The fission track results imply that the regional compression field plays an important role for the differential exhumation between individual fault blocks of the Huangshan pluton.

关键词： Huangshan pluton thermal overprints apatite fission track cooling fault block

Quantifying Hypochlorous Acid Concentration in Environmental Water Using Smartphone Colorimetry

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Journal of Analysis and Testing 2021年第4期5卷 360-369页

作者： Shuai He Hui Dong Yuanqiang Hao Yintang Zhang Yanli Zhou Fangyuan Zhang Jie Li yingying jia Guoqing Xiao Maotian Xu College of Materials Science and Engineering Xi’an University of Architecture and TechnologyXi’an 710055China Henan Key Laboratory of Biomolecular Recognition and Sensing College of Chemistry and Chemical EngineeringHenan Joint International Research Laboratory of Chemo/Biosensing and Early Diagnosis of Major DiseasesShangqiu Normal UniversityShangqiu 476000China

In this study,we developed an eff ective method to detect hypochlorite acid(HClO)by using methylene blue(MB)derivative(BPY1).BPY1 was selectively oxidized through HClO,and the solution color changed from colorless to *** the presence of HClO,the ultraviolet–visible(UV–vis)spectra and concentration of HClO had a linear relationship with a detection limit of 0.5μ***,a test paper for HClO monitoring was successfully prepared using the BPY1 probe,and the observed detection limit by the naked eye was estimated at 5μ***,using the BPY1 probe,HClO could also be detected through smartphone colorimetry,and the method showed a good recovery ranging from 98.7 to 104.0%for HClO detection in an actual water *** for developing countries,such a low-cost and highly sensitive detection method provides a simple and practical method for monitoring HClO in water.

关键词： Smartphone colorimetry RGB Test strips Hypochlorite acid Methylene blue

Epigenetic regulation in Wnt signaling

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Epigenetic regulation in Wnt signaling

中国生物化学与分子生物学会第十届会员代表大会暨全国学术会议

作者： yingying jia Zhenfei Li Fen Nie Lin Li State Key Laboratory of Molecular Biology Institute of Biochemistry and Cell BiologyShanghai Institutes for Biological SciencesChinese Academy of Sciences

The canonical Wnt signaling pathway controls and regulates many developmental processes through a complex of P-catenin and the HMG-box transcription factors of the LEF1/TCFs *** co-activators including histone modification enzymes are recruited into P-catenin·LEF1/ TCFs transcription complex at target gene promoters to facilitate gene *** we show that two novel

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南天山乌什前陆逆冲褶皱构造带的晚新生代构造地貌特征与地震活动

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地质科学 2010年第4期45卷 917-929页

作者：付碧宏贾营营中国科学院地质与地球物理研究所地球深部研究重点实验室北京100029

乌什逆冲断褶带位于南天山库车前陆逆冲褶皱构造带的西段,对该地区晚新生代构造活动的研究有利于加深对南天山前陆逆冲构造带的认识。本文通过对卫星遥感影像和DEM数据的解译分析,并结合研究区野外考察及典型地震反射剖面的分析,表明乌... 详细信息

乌什逆冲断褶带位于南天山库车前陆逆冲褶皱构造带的西段,对该地区晚新生代构造活动的研究有利于加深对南天山前陆逆冲构造带的认识。本文通过对卫星遥感影像和DEM数据的解译分析,并结合研究区野外考察及典型地震反射剖面的分析,表明乌什逆冲断褶带东部地貌演化受褶皱生长影响较为深刻,发育一系列由新到老的冲积扇和风口。台兰河中游河流阶地和冰碛物均被秋里塔格断层错断,阶地断距为3.1～6.7 m,台兰期冰碛物(M_2)断距约80 m。秋里塔格断裂第四纪以来水平缩短速率约为1.23～1.59 mm/a。西部地区发育一系列逆冲断层,并发育典型的活动断层陡坎。乌什凹陷地震活动也具有明显的西强东弱的特点,地震活动具有沿断层呈带状分布的特点。乌什逆冲断褶带位于南天山造山带东西构造的转换地带,地震活动西部明显强于东部,且具有呈带状沿南天山及其山前逆冲断裂带分布的特点。历史地震分析表明上个世纪以来该区域未有7级以上地震发生,但其西部地区6级以上地震频发,随着阿克苏地区区域经济的快速发展和人口的快速增长,乌什逆冲断褶带的地震活动性应该引起地质学家更加深入的关注和研究。

关键词：逆冲断裂褶皱构造地貌地震活动晚新生代南天山

Caprin-2 regulate constitutive LRP5/6 phosphorylation through the mitotic CDK14/Cyclin Y complex

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Caprin-2 regulate constitutive LRP5/6 phosphorylation throug...

中国生物化学与分子生物学会第十一次会员代表大会暨2014年全国学术会议

作者： Wang Wang Xin yingying jia Xiaomin Song Lin Li SIBCB

The Wnt/β-catenin signaling pathway has a crucial role in embryonic development,stemcell maintenance and human ***,we identified Caprin-2 as a positive regulatorin canonical Wnt signaling,which can facilitate the Wnt-stimulated LRP5/6 *** we further uncovered that Caprin-2 can not only promote the Wnt ligand-depended LRP5/6phosphorylation but also participate in the regulation of the constitutive(non-Wnt-induced)LRP5/6 *** constitutive LRP5/6 phosphorylationis mediated by a mitotic Cyclin Y/CDK14 complex that phosphorylates LRP6S1490in a cell cycle-dependent manner and this increases the receptiveness of cells for incomingWnt *** found that Caprin-2 can interact with the Cyclin Y/CDK14 complexand knockdown of Caprin-2 can dramatically disrupt the interaction between Cyclin Y *** accordance with this’the constitutive LRP5/6 phosphorylation is also inhibitedwhen Caprin-2 is knocked *** primary study shows that the expression level ofCaprin-2 is also cell ***,it is reasonable to speculate that Caprin-2 couldact as an important regulator for the function of Cyclin Y/CDK14 complex during G2/*** also crossed Caprin-2 knockout mouse with the mouse strains harboring knockoutallele of Cyclin Y and Cyclin Y ***,we expect to explore further the function ofCaprin-2 at the whole animal level in embryonic development,tumorigenesis and other aspectsof biological functions.

关键词： Caprin-2 Cyclin Y/CDK14 constitutive LRP5/6 phosphorylation

Late Miocene stepwise aridification in the Asian interior and the interplay between tectonics and climate

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Late Miocene stepwise aridification in the Asian interior an...

中国科学院地质与地球物理研究所2015年度（第15届）学术年会

作者： Jimin Sun Zhijun Gong Zhonghua Tian yingying jia Brian Windley Key Laboratory of Cenozoic Geology and Environment Institute of Geology and Geophysics Chinese Academy of Sciences CAS Center for Excellence in Tibetan Plateau Earth Sciences Department of Geology The University of Leicester

The mid-latitudinal central Asian continent is characterized by large sand deserts and Gobi(stony desert). In this context, it is of interest to study the timing and forcing mechanisms of aridification in the region. Here we present multiple geochemical climatic proxies from late Cenozoic strata in the Tarim Basin of northwestern China, a region sensitive to climatic change. The results yield long-term climatic records covering a time interval of 13.3 to2.5 Ma. We find that a general trend towards a dry climate was superimposed by two stepwise aridification events, the first lesser aridity phase occurred at 7–5.3 Ma and the second extreme aridity episode was initiated at 5.3 Ma. Based on the correlation between climatic change and regional tectonic events, we propose a mechanism to explain the climatic variations. The general long-term drying trend since the mid-Miocene was a response to global climatic cooling, while the stepwise aridification since the latest Miocene was controlled mainly by regional tectonic uplift.

关键词： Late Cenozoic Aridification Paleoclimate Forcing mechanism Central Asia

Synthesis of Functional Molecules based on Porphyrin and Azaporphyrin

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Synthesis of Functional Molecules based on Porphyrin and Aza...

中国化学会第四届卟啉与酞菁学术研讨会

作者： yingying jia Ling Xu Bangshao Yin Mingbo Zhou jianxin Song Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research(Ministry of Education) Key Laboratory of Application and Assemble of Organic Functional Molecules Hunan Normal University

Azaporphyrins have large delocalized π electron system similar to porphyrin and phthalocyanine *** compounds have been attracting considerable attention because of their potential applications such as solar cells,dyes,organic semiconductors and magnetic chemistry.β-β directly linked porphyrinazaporphyrin hybrid arrays [1] obtained by Suzuki-Miyaura cross-coupling reaction could be oxidized by DDQ and FeCl [2,3] to afford fused porphyrin-azaporphyrin *** photo-physical and electro-chemical properties of new compounds were examined by UV-visible spectroscopy and cyclic *** results reveal their triply linked tapes were different from those chain hybrids,such as broader Soret bands and Q-bands,its absorption to near infrared region and smaller HOMO-LUMO gap,which demonstrate that triply linked porphyrin-azaporphyrin arrays have larger π conjugate *** investigation on the synthesis of more elaborate π-extended porphyrin-azaporphyrin hybrid tapes is underway in our laboratory.

关键词： porphyrin-azaporphyrin array large π conjugate system